medetomidine has been researched along with Pain in 27 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (7.41) | 18.7374 |
| 1990's | 19 (70.37) | 18.2507 |
| 2000's | 2 (7.41) | 29.6817 |
| 2010's | 4 (14.81) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Iranmanesh, F; Sakhaee, E; Samimi, AS | 1 |
| Dzikiti, BT; Fosgate, GT; Rioja, E; Stegmann, FG; Venter, FJ; Zeiler, GE | 1 |
| Bosmans, T; de Rooster, H; Duchateau, L; Goethals, K; Moons, CP; Polis, I; Porters, N | 1 |
| Bortolami, E; Murrell, JC; Slingsby, LS | 1 |
| Aithal, HP; Kinjavdekar, P; Singh, V | 1 |
| Herrero, JF; Molina, C | 1 |
| Kalso, EA; Kontinen, VK | 1 |
| Hämäläinen, MM; Pertovaara, A | 2 |
| Jyväsjärvi, E; Kauppila, T; Pertovaara, A; Taira, T; Tanila, H | 1 |
| Luukko, M; Pertovaara, A | 1 |
| Ozaki, GT; Penning, JP; Sabbe, MB; Yaksh, TL | 1 |
| Carlson, S; Hämäläinen, MM; Kauppila, T; Mecke, E; Pertovaara, A | 1 |
| Bravo, R; Herdegen, T; Pertovaara, A | 1 |
| Puke, MJ; Wiesenfeld-Hallin, Z | 1 |
| Benson, J; Branson, KR; Ko, JC; Thurmon, JC; Tranquilli, WJ | 1 |
| Brenner, GM; Stevens, CW | 1 |
| Pertovaara, A; Wei, H | 1 |
| Calcutt, NA; Chaplan, SR | 1 |
| Kalso, E; Kontinen, VK; Paananen, S | 1 |
| Guo, TZ; Kingery, WS; Maze, M; Poree, LR | 1 |
| Kauppila, T; Kemppainen, P; Pertovaara, A; Tanila, H | 1 |
| Kauppila, T; Kemppainen, P; Pertovaara, A | 1 |
| Jyväsjärvi, E; Kalso, E; Kauppila, T; Pertovaara, A | 1 |
| Bagley, J; Harris, S; Lin, BS; Lloyd, P; Messineo, E; Ossipov, MH | 1 |
| Vainio, O; Yliselä, E | 1 |
| Stenberg, D | 1 |
1 review(s) available for medetomidine and Pain
| Article | Year |
|---|---|
Physiological role of alpha 2-adrenoceptors in the regulation of vigilance and pain: effect of medetomidine.
Topics: Adrenergic alpha-Agonists; Anesthesia; Animals; Arousal; Cats; Humans; Hypnotics and Sedatives; Imidazoles; Medetomidine; Pain; Receptors, Adrenergic, alpha | 1989 |
3 trial(s) available for medetomidine and Pain
| Article | Year |
|---|---|
Evaluation of sedative, analgesic, physiological, and laboratory effects of two doses off medetomidine and xylazine in dromedary calves.
Topics: Analgesia; Animals; Camelus; Conscious Sedation; Hypnotics and Sedatives; Male; Medetomidine; Pain; Xylazine | 2019 |
Anaesthetic, analgesic and cardiorespiratory effects of intramuscular medetomidine-ketamine combination alone or with morphine or tramadol for orchiectomy in cats.
Topics: Analgesia; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthetics, Combined; Anesthetics, Dissociative; Animals; Carbon Dioxide; Cats; Drug Combinations; Drug Therapy, Combination; Injections, Intramuscular; Ketamine; Male; Medetomidine; Morphine; Orchiectomy; Oxygen; Pain; Tramadol; Treatment Outcome | 2014 |
Effect of bupivacaine on epidural analgesia produced by xylazine or medetomidine in buffaloes (Bubalus bubalis).
Topics: Analgesics; Animals; Buffaloes; Bupivacaine; Drug Interactions; Drug Therapy, Combination; Injections, Epidural; Male; Medetomidine; Pain; Time Factors; Xylazine | 2009 |
23 other study(ies) available for medetomidine and Pain
| Article | Year |
|---|---|
Prepubertal gonadectomy in cats: different injectable anaesthetic combinations and comparison with gonadectomy at traditional age.
Topics: Anesthesia; Anesthetics; Animals; Buprenorphine; Cats; Dexmedetomidine; Female; Injections, Intramuscular; Ketamine; Medetomidine; Orchiectomy; Ovariectomy; Pain; Random Allocation; Sexual Maturation | 2015 |
Methadone in combination with medetomidine as premedication prior to ovariohysterectomy and castration in the cat.
Topics: Analgesia; Analgesics, Opioid; Anesthesia, General; Animals; Cat Diseases; Cats; Drug Therapy, Combination; Female; Hysterectomy; Male; Medetomidine; Methadone; Orchiectomy; Ovariectomy; Pain; Premedication | 2015 |
The influence of the time course of inflammation and spinalization on the antinociceptive activity of the alpha2-adrenoceptor agonist medetomidine.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-Agonists; Analgesics; Analysis of Variance; Animals; Behavior, Animal; Carrageenan; Dose-Response Relationship, Drug; Electric Stimulation; Hindlimb; Inflammation; Male; Medetomidine; Pain; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-2; Reflex; Spinal Cord Injuries; Time Factors | 2006 |
Differential modulation of alpha 2-adrenergic and mu-opioid spinal antinociception by neuropeptide FF.
Topics: Adrenergic alpha-Agonists; Analgesics, Opioid; Animals; Dose-Response Relationship, Drug; Drug Synergism; Imidazoles; Male; Medetomidine; Morphine; Naltrexone; Narcotic Antagonists; Neuropeptides; Oligopeptides; Pain; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Receptors, Opioid, mu; Spinal Cord; Time Factors | 1995 |
Spinal potentiation and supraspinal additivity in the antinociceptive interaction between systemically administered alpha 2-adrenoceptor agonist and cocaine in the rat.
Topics: Adrenergic alpha-Agonists; Analgesics, Non-Narcotic; Analysis of Variance; Animals; Cocaine; Drug Synergism; Hot Temperature; Imidazoles; Male; Medetomidine; Pain; Rats; Rats, Wistar; Spinal Cord; Tail | 1994 |
Activation of alpha 2-adrenergic receptors decreases nerve trauma-induced afferent barrage but not autotomy.
Topics: Adrenergic alpha-2 Receptor Agonists; Afferent Pathways; Animals; Denervation; Electric Stimulation; Imidazoles; Injections, Intraperitoneal; Male; Medetomidine; Movement; Pain; Phrenic Nerve; Rats; Rats, Wistar; Self Mutilation; Spinal Cord; Tibial Nerve; Wounds and Injuries | 1995 |
Influence of an experimental peripheral mononeuropathy on the responses of medial bulboreticular neurons to noxious skin stimulation and the modulation of the responses by an alpha 2-adrenoceptor agonist in the rat.
Topics: Adrenergic alpha-Agonists; Analysis of Variance; Animals; Dose-Response Relationship, Drug; Electrophysiology; Hyperalgesia; Imidazoles; Medetomidine; Medulla Oblongata; Neurons; Pain; Rats; Rats, Wistar; Receptors, Adrenergic, beta-2; Reference Values; Sciatic Nerve; Skin | 1993 |
Spinal and systemic action of the alpha 2 receptor agonist dexmedetomidine in dogs. Antinociception and carbon dioxide response.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Anesthesia, Epidural; Anesthesia, Spinal; Animals; Body Temperature; Carbon Dioxide; Dogs; Dose-Response Relationship, Drug; Forelimb; Heart Rate; Hindlimb; Imidazoles; Infusions, Intravenous; Infusions, Parenteral; Medetomidine; Motor Activity; Naloxone; Pain; Receptors, Adrenergic, alpha-2; Respiration | 1994 |
Dissociation of the alpha 2-adrenergic antinociception from sedation following microinjection of medetomidine into the locus coeruleus in rats.
Topics: Adrenergic alpha-Antagonists; Animals; Decerebrate State; Formaldehyde; Hypnotics and Sedatives; Imidazoles; Locus Coeruleus; Male; Medetomidine; Microinjections; Motor Activity; Pain; Pain Measurement; Rats; Rats, Wistar; Spinal Cord | 1994 |
Induction and suppression of immediate-early genes in the rat brain by a selective alpha-2-adrenoceptor agonist and antagonist following noxious peripheral stimulation.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Behavior, Animal; Brain; DNA-Binding Proteins; Early Growth Response Protein 1; Gene Expression Regulation; Genes, fos; Genes, jun; Imidazoles; Immediate-Early Proteins; Male; Medetomidine; Pain; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-jun; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha; Spinal Cord; Thalamus; Transcription Factors | 1993 |
The differential effects of morphine and the alpha 2-adrenoceptor agonists clonidine and dexmedetomidine on the prevention and treatment of experimental neuropathic pain.
Topics: Adrenergic alpha-Agonists; Animals; Clonidine; Imidazoles; Male; Medetomidine; Morphine; Motor Activity; Pain; Rats; Rats, Sprague-Dawley; Sciatic Nerve; Self Mutilation | 1993 |
The rostroventromedial medulla is not involved in alpha 2-adrenoceptor-mediated antinociception in the rat.
Topics: Analysis of Variance; Animals; Cerebellum; Clonidine; Dose-Response Relationship, Drug; Hot Temperature; Imidazoles; Lidocaine; Male; Medetomidine; Medulla Oblongata; Microinjections; Pain; Periaqueductal Gray; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-2; Reflex; Skin Temperature; Spinal Cord; Time Factors | 1993 |
Duration of analgesia induced by epidurally administered morphine and medetomidine in dogs.
Topics: Analgesia, Epidural; Analgesics; Animals; Dogs; Drug Combinations; Female; Imidazoles; Injections, Epidural; Medetomidine; Morphine; Motor Activity; Pain; Pain Measurement; Time Factors | 1993 |
Spinal administration of adrenergic agents produces analgesia in amphibians.
Topics: Analgesics, Non-Narcotic; Animals; Clonidine; Epinephrine; Imidazoles; Injections, Spinal; Medetomidine; Norepinephrine; Pain; Rana esculenta | 1996 |
Peripherally administered alpha2-adrenoceptor agonist in the modulation of chronic allodynia induced by spinal nerve ligation in the rat.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Dose-Response Relationship, Drug; Imidazoles; Ligation; Male; Medetomidine; Pain; Pain Measurement; Rats; Rats, Wistar; Spinal Nerves | 1997 |
Spinal pharmacology of tactile allodynia in diabetic rats.
Topics: 2-Amino-5-phosphonovalerate; Analgesics, Non-Narcotic; Analgesics, Opioid; Animals; Anti-Bacterial Agents; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Female; Imidazoles; Injections, Spinal; Medetomidine; Morphine; Pain; Quinoxalines; Rats; Rats, Sprague-Dawley; Spinal Cord; Streptozocin | 1997 |
The effects of the alpha2-adrenergic agonist, dexmedetomidine, in the spinal nerve ligation model of neuropathic pain in rats.
Topics: Adrenergic alpha-Agonists; Animals; Cold Temperature; Extremities; Hot Temperature; Imidazoles; Male; Medetomidine; Models, Biological; Pain; Peripheral Nerve Injuries; Peripheral Nervous System Diseases; Rats; Rats, Sprague-Dawley; Spinal Nerves | 1998 |
The analgesic potency of dexmedetomidine is enhanced after nerve injury: a possible role for peripheral alpha2-adrenoceptors.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Analgesics, Non-Narcotic; Animals; Dose-Response Relationship, Drug; Hyperalgesia; Imidazoles; Male; Medetomidine; Pain; Pain Threshold; Quinolizines; Rats; Rats, Sprague-Dawley; Spinal Nerves | 1998 |
Effect of systemic medetomidine, an alpha 2 adrenoceptor agonist, on experimental pain in humans.
Topics: Adrenergic alpha-Agonists; Adult; Dose-Response Relationship, Drug; Humans; Imidazoles; Male; Medetomidine; Pain; Sensory Thresholds | 1991 |
The effects of medetomidine, an alpha-2-adrenoceptor agonist, and cocaine on the tooth pulp-evoked jaw-opening reflex in cat.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Anesthesia; Animals; Cats; Cocaine; Dental Pulp; Dose-Response Relationship, Drug; Electric Stimulation; Electromyography; Imidazoles; Jaw; Medetomidine; Pain; Reflex | 1991 |
Involvement of supraspinal and spinal segmental alpha-2-adrenergic mechanisms in the medetomidine-induced antinociception.
Topics: Adrenergic alpha-Agonists; Afferent Pathways; Analgesics; Animals; Hot Temperature; Imidazoles; Mechanoreceptors; Medetomidine; Neurons, Afferent; Pain; Rats; Rats, Inbred Strains; Reaction Time; Receptors, Adrenergic, alpha; Reflex; Sensory Thresholds; Spinal Cord; Spinothalamic Tracts; Stress, Mechanical; Tail; Thalamus | 1991 |
Antinociceptive interaction between opioids and medetomidine: systemic additivity and spinal synergy.
Topics: Adrenergic alpha-Agonists; Analgesics, Opioid; Animals; Drug Interactions; Drug Synergism; Fentanyl; Imidazoles; Injections, Intravenous; Injections, Spinal; Male; Medetomidine; Meperidine; Morphine; Pain; Pain Measurement; Rats; Rats, Inbred Strains | 1990 |
Effects of medetomidine on the experimental auricular pain in dogs.
Topics: Adrenergic alpha-Agonists; Analgesics; Animals; Dogs; Double-Blind Method; Ear Diseases; Female; Imidazoles; Male; Medetomidine; Pain | 1989 |