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meclofenamic acid and Hypertension, Pulmonary

meclofenamic acid has been researched along with Hypertension, Pulmonary in 16 studies

Meclofenamic Acid: A non-steroidal anti-inflammatory agent with antipyretic and antigranulation activities. It also inhibits prostaglandin biosynthesis.
meclofenamic acid : An aminobenzoic acid that is anthranilic acid in which one of the hydrogens attached to the nitrogen is replaced by a 2,6-dichloro-3-methylphenyl group. A non-steroidal anti-inflammatory drug, it is used as the sodium salt for the treatment of dysmenorrhoea (painful periods), osteoarthritis and rheumatoid arthritis.

Hypertension, Pulmonary: Increased VASCULAR RESISTANCE in the PULMONARY CIRCULATION, usually secondary to HEART DISEASES or LUNG DISEASES.

Research Excerpts

ExcerptRelevanceReference
"We wanted to assess the respective roles of arachidonic acid products and nitric oxide in the modulation of pulmonary hypertension in chronically hypoxic rats."3.68Attenuation of chronic hypoxic pulmonary hypertension in rats by cyclooxygenase products and by nitric oxide. ( Barer, G; Howard, P; Kapeller, K; Russell, P; Wright, C, 1993)

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-19908 (50.00)18.7374
1990's6 (37.50)18.2507
2000's2 (12.50)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Wideman, RF1
Bowen, OT1
Erf, GF1
Gee, MH2
Perkowski, SZ2
Havill, AM2
Flynn, JT2
Snapper, JR3
Bernard, GR1
Hinson, JM1
Hutchison, AA1
Loyd, JE2
Ogletree, ML5
Brigham, KL5
Begley, CJ1
Meyrick, BO2
Newman, JH1
Russell, P1
Wright, C1
Kapeller, K1
Barer, G1
Howard, P1
Wong, J2
Vanderford, PA2
Fineman, JR2
Soifer, SJ2
Chang, R1
Eddahibi, S1
Raffestin, B1
Pham, I1
Launay, JM1
Aegerter, P1
Sitbon, M1
Adnot, S1
Lu, W1
Lefferts, PL1
Thabes, JS1
Kaye, AD1
De Witt, BJ1
Anwar, M1
Smith, DE1
Feng, CJ1
Kadowitz, PJ1
Nossaman, BD1
Weir, EK1
Will, DH1
Alexander, AF1
McMurtry, IF2
Looga, R1
Reeves, JT1
Grover, RF1
Ashmore, RC1
Rodman, DM1
Sato, K1
Webb, SA1
O'Brien, RF1
Stelzner, TJ1

Trials

1 trial available for meclofenamic acid and Hypertension, Pulmonary

ArticleYear
Broiler pulmonary hypertensive responses during lipopolysaccharide-induced tolerance and cyclooxygenase inhibition.
    Poultry science, 2009, Volume: 88, Issue:1

    Topics: Animals; Chickens; Cyclooxygenase Inhibitors; Hypertension, Pulmonary; Lipopolysaccharides; Male; Me

2009

Other Studies

15 other studies available for meclofenamic acid and Hypertension, Pulmonary

ArticleYear
Role of prostaglandins and leukotrienes in complement-initiated lung vascular injury.
    Chest, 1983, Volume: 83, Issue:5 Suppl

    Topics: Animals; Catechols; Complement Activation; Epoprostenol; Hypertension, Pulmonary; Hypoxia; Leukocyte

1983
Role of intrapulmonary release of eicosanoids and superoxide anion as mediators of pulmonary dysfunction and endothelial injury in sheep with intermittent complement activation.
    Circulation research, 1983, Volume: 53, Issue:5

    Topics: Animals; Capillary Permeability; Chemotaxis, Leukocyte; Complement Activation; Endothelium; Hyperten

1983
Endotoxemia-induced leukopenia in sheep. Correlation with lung vascular permeability and hypoxemia but not with pulmonary hypertension.
    The American review of respiratory disease, 1983, Volume: 127, Issue:3

    Topics: Animals; Capillary Permeability; Endotoxins; Escherichia coli; Hypertension, Pulmonary; Hypoxia; Leu

1983
Modification of pulmonary responses to endotoxemia in awake sheep by steroidal and nonsteroidal anti-inflammatory agents.
    The American review of respiratory disease, 1984, Volume: 130, Issue:6

    Topics: Animals; Anti-Inflammatory Agents; Consciousness; Endotoxins; Escherichia coli; Hypertension, Pulmon

1984
Cyclooxygenase inhibition during phorbol-induced granulocyte stimulation in awake sheep.
    Journal of applied physiology: respiratory, environmental and exercise physiology, 1984, Volume: 56, Issue:4

    Topics: Animals; Consciousness; Cyclooxygenase Inhibitors; Granulocytes; Hypertension, Pulmonary; Hypoxia; I

1984
Effects of cyclooxygenase inhibitors on pulmonary vascular responses to endotoxin in unanesthetized sheep.
    Prostaglandins, leukotrienes, and medicine, 1982, Volume: 8, Issue:5

    Topics: Animals; Blood Pressure; Capillary Permeability; Cyclooxygenase Inhibitors; Endotoxins; Escherichia

1982
Attenuation of chronic hypoxic pulmonary hypertension in rats by cyclooxygenase products and by nitric oxide.
    The European respiratory journal, 1993, Volume: 6, Issue:10

    Topics: Amino Acid Oxidoreductases; Animals; Arachidonic Acid; Arginine; Blood Pressure; Dilatation; Dinopro

1993
Developmental effects of endothelin-1 on the pulmonary circulation in sheep.
    Pediatric research, 1994, Volume: 36, Issue:3

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Aging; Animals; Arginine; Endoth

1994
Endothelin-1 produces pulmonary vasodilation in the intact newborn lamb.
    The American journal of physiology, 1993, Volume: 265, Issue:4 Pt 2

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Animals, Newborn; Argin

1993
Treatment with 5-HT potentiates development of pulmonary hypertension in chronically hypoxic rats.
    The American journal of physiology, 1997, Volume: 272, Issue:3 Pt 2

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Cyclooxygenase Inhibito

1997
Cyclooxygenase products contribute to endothelin-induced pulmonary hypertension and altered lung mechanics in sheep.
    Pulmonary pharmacology & therapeutics, 1997, Volume: 10, Issue:2

    Topics: Animals; Blood Pressure; Cyclooxygenase Inhibitors; Endothelin-1; Endothelin-2; Endothelin-3; Endoth

1997
Analysis of responses of garlic derivatives in the pulmonary vascular bed of the rat.
    Journal of applied physiology (Bethesda, Md. : 1985), 2000, Volume: 89, Issue:1

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adamantane; Allyl Compounds; Ani

2000
Vascular hypertrophy in cattle susceptible to hypoxic pulmonary hypertension.
    Journal of applied physiology: respiratory, environmental and exercise physiology, 1979, Volume: 46, Issue:3

    Topics: Animals; Cattle; Hypertension, Pulmonary; Lung; Meclofenamic Acid; Muscle, Smooth; Prostaglandins E;

1979
Paradoxical constriction to platelets by arteries from rats with pulmonary hypertension.
    The American journal of physiology, 1991, Volume: 260, Issue:6 Pt 2

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Acetylcholine; Adenosine Diphosp

1991
Direct and indirect effects of leukotriene D4 on the lungs of unanesthetized sheep.
    Respiration; international review of thoracic diseases, 1987, Volume: 51, Issue:4

    Topics: 6-Ketoprostaglandin F1 alpha; Anesthesia; Animals; Arachidonate 5-Lipoxygenase; Blood Pressure; Fema

1987