Page last updated: 2024-10-30

meclofenamic acid and Coronary Disease

meclofenamic acid has been researched along with Coronary Disease in 7 studies

Meclofenamic Acid: A non-steroidal anti-inflammatory agent with antipyretic and antigranulation activities. It also inhibits prostaglandin biosynthesis.
meclofenamic acid : An aminobenzoic acid that is anthranilic acid in which one of the hydrogens attached to the nitrogen is replaced by a 2,6-dichloro-3-methylphenyl group. A non-steroidal anti-inflammatory drug, it is used as the sodium salt for the treatment of dysmenorrhoea (painful periods), osteoarthritis and rheumatoid arthritis.

Coronary Disease: An imbalance between myocardial functional requirements and the capacity of the CORONARY VESSELS to supply sufficient blood flow. It is a form of MYOCARDIAL ISCHEMIA (insufficient blood supply to the heart muscle) caused by a decreased capacity of the coronary vessels.

Research Excerpts

ExcerptRelevanceReference
"The effects of the inhibitors on reactive hyperemia resulting from 5-, 10-, 15-, and 20-second occlusions and the dilation resulting from 90-second exposure to 8% O2 were also examined."1.26Prostaglandins and the control of blood flow in the canine myocardium. ( Hintze, TH; Kaley, G, 1977)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19905 (71.43)18.7374
1990's2 (28.57)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Lefer, AM2
Araki, H1
Okamatsu, S1
Alexander, RW1
Kent, KM1
Pisano, JJ1
Keiser, HR1
Cooper, T1
Hintze, TH1
Kaley, G1
Ogletree, ML2
Grover, GJ1
Hedberg, A1
Vegh, A1
Szekeres, L1
Parratt, JR1
Thames, MD1
Minisi, AJ1

Other Studies

7 other studies available for meclofenamic acid and Coronary Disease

ArticleYear
Beneficial actions of a free radical scavenger in traumatic shock and myocardial ischemia.
    Circulatory shock, 1981, Volume: 8, Issue:3

    Topics: Animals; Arachidonic Acids; Butylated Hydroxytoluene; Cats; Coronary Disease; Creatine Kinase; Femal

1981
Regulation of postocclusive hyperemia by endogenously synthesized prostaglandins in the dog heart.
    The Journal of clinical investigation, 1975, Volume: 55, Issue:6

    Topics: Adenosine; Animals; Coronary Circulation; Coronary Disease; Coronary Vessels; Cyclooxygenase Inhibit

1975
Prostaglandins and the control of blood flow in the canine myocardium.
    Circulation research, 1977, Volume: 40, Issue:3

    Topics: Adenosine; Angiotensin II; Animals; Arachidonic Acids; Blood Pressure; Coronary Circulation; Coronar

1977
Influence of nonsteroidal anti-inflammatory agents on myocardial ischemia in the cat.
    The Journal of pharmacology and experimental therapeutics, 1976, Volume: 197, Issue:3

    Topics: Animals; Anti-Inflammatory Agents; Aorta, Thoracic; Aspirin; Blood Pressure; Cats; Coronary Disease;

1976
Direct myocardial effects of the thromboxane A2/prostaglandin H2 agonists U-46619 and SQ 26,655 under ischemic and nonischemic conditions.
    Pharmacology, 1990, Volume: 41, Issue:1

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Coronary Circulation; C

1990
Protective effects of preconditioning of the ischaemic myocardium involve cyclo-oxygenase products.
    Cardiovascular research, 1990, Volume: 24, Issue:12

    Topics: Animals; Coronary Disease; Cyclooxygenase Inhibitors; Dogs; Electrocardiography; Female; Heart Rate;

1990
Reflex responses to myocardial ischemia and reperfusion. Role of prostaglandins.
    Circulation, 1989, Volume: 80, Issue:6

    Topics: Afferent Pathways; Animals; Coronary Disease; Dogs; Heart; Indomethacin; Kidney; Mechanoreceptors; M

1989