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meclofenamic acid and Brain Neoplasms

meclofenamic acid has been researched along with Brain Neoplasms in 4 studies

Meclofenamic Acid: A non-steroidal anti-inflammatory agent with antipyretic and antigranulation activities. It also inhibits prostaglandin biosynthesis.
meclofenamic acid : An aminobenzoic acid that is anthranilic acid in which one of the hydrogens attached to the nitrogen is replaced by a 2,6-dichloro-3-methylphenyl group. A non-steroidal anti-inflammatory drug, it is used as the sodium salt for the treatment of dysmenorrhoea (painful periods), osteoarthritis and rheumatoid arthritis.

Brain Neoplasms: Neoplasms of the intracranial components of the central nervous system, including the cerebral hemispheres, basal ganglia, hypothalamus, thalamus, brain stem, and cerebellum. Brain neoplasms are subdivided into primary (originating from brain tissue) and secondary (i.e., metastatic) forms. Primary neoplasms are subdivided into benign and malignant forms. In general, brain tumors may also be classified by age of onset, histologic type, or presenting location in the brain.

Research Excerpts

ExcerptRelevanceReference
" The orally bioavailable modulators of gap junctions meclofenamate and tonabersat break this paracrine loop, and we provide proof-of-principle that these drugs could be used to treat established brain metastasis."1.43Carcinoma-astrocyte gap junctions promote brain metastasis by cGAMP transfer. ( Boire, A; Chen, Q; Cross, JR; Er, EE; Jacob, L; Jin, X; Lopez-Soto, A; Massagué, J; Patwa, R; Shah, H; Valiente, M; Xu, K, 2016)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (50.00)24.3611
2020's2 (50.00)2.80

Authors

AuthorsStudies
Xiao, L1
Li, X1
Mu, Z1
Zhou, J1
Zhou, P1
Xie, C1
Jiang, S1
Schneider, M1
Vollmer, L1
Potthoff, AL1
Ravi, VM1
Evert, BO1
Rahman, MA1
Sarowar, S1
Kueckelhaus, J1
Will, P1
Zurhorst, D1
Joseph, K1
Maier, JP1
Neidert, N1
d'Errico, P1
Meyer-Luehmann, M1
Hofmann, UG1
Dolf, A1
Salomoni, P1
Güresir, E1
Enger, PØ1
Chekenya, M1
Pietsch, T1
Schuss, P1
Schnell, O1
Westhoff, MA1
Beck, J1
Vatter, H1
Waha, A1
Herrlinger, U1
Heiland, DH1
Chen, Q1
Boire, A1
Jin, X1
Valiente, M1
Er, EE1
Lopez-Soto, A1
Jacob, L1
Patwa, R1
Shah, H1
Xu, K1
Cross, JR1
Massagué, J1
Cui, Q1
Shi, H1
Ye, P1
Li, L1
Qu, Q1
Sun, G2
Lu, Z1
Huang, Y1
Yang, CG1
Riggs, AD1
He, C1
Shi, Y1

Other Studies

4 other studies available for meclofenamic acid and Brain Neoplasms

ArticleYear
FTO Inhibition Enhances the Antitumor Effect of Temozolomide by Targeting MYC-miR-155/23a Cluster-MXI1 Feedback Circuit in Glioma.
    Cancer research, 2020, 09-15, Volume: 80, Issue:18

    Topics: Alpha-Ketoglutarate-Dependent Dioxygenase FTO; Animals; Antineoplastic Agents, Alkylating; Basic Hel

2020
Meclofenamate causes loss of cellular tethering and decoupling of functional networks in glioblastoma.
    Neuro-oncology, 2021, 11-02, Volume: 23, Issue:11

    Topics: Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Glioblastoma; Humans; In Vitro Techniques; Me

2021
Carcinoma-astrocyte gap junctions promote brain metastasis by cGAMP transfer.
    Nature, 2016, 05-26, Volume: 533, Issue:7604

    Topics: Animals; Astrocytes; Benzamides; Benzopyrans; Brain Neoplasms; Breast Neoplasms; Cadherins; Cell Lin

2016
m
    Cell reports, 2017, 03-14, Volume: 18, Issue:11

    Topics: Adenosine; Alpha-Ketoglutarate-Dependent Dioxygenase FTO; Animals; Base Sequence; Brain Neoplasms; C

2017