meclofenamic acid has been researched along with Blood Pressure, High in 21 studies
Meclofenamic Acid: A non-steroidal anti-inflammatory agent with antipyretic and antigranulation activities. It also inhibits prostaglandin biosynthesis.
meclofenamic acid : An aminobenzoic acid that is anthranilic acid in which one of the hydrogens attached to the nitrogen is replaced by a 2,6-dichloro-3-methylphenyl group. A non-steroidal anti-inflammatory drug, it is used as the sodium salt for the treatment of dysmenorrhoea (painful periods), osteoarthritis and rheumatoid arthritis.
| Excerpt | Relevance | Reference |
|---|---|---|
| " sar1gly8AII, abolished the hypertensive response to acute ureteral obstruction, and pretreatment with 2 mg/kg of either indomethacin (n=6) or meclofenamate (n=3), 15 min before obstruction, prevented the hyperemic response." | 3.66 | Prostaglandin-mediated hyperemia and renin-mediated hypertension during acute ureteral obstruction. ( Aisenbrey, G; Burke, TJ; Cadnapaphornchai, P; McDonald, KM; Schrier, RW, 1978) |
| "The hypertension is accompanied by increases in plasma renin activity and can be prevented with intravenous L-arginine administration." | 1.29 | Long-term cardiovascular role of nitric oxide in conscious rats. ( Brands, MW; Hu, L; Manning, RD, 1994) |
| "Our recent observation that the chronic administration of indomethacin (3." | 1.28 | Resistance of the renal biosynthesis of prostaglandin E2 to the inhibitory effect of indomethacin in the rat in vivo. ( Falardeau, P; Hui, R, 1990) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 12 (57.14) | 18.7374 |
| 1990's | 8 (38.10) | 18.2507 |
| 2000's | 1 (4.76) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Pearson, JT | 1 |
| Shirai, M | 1 |
| Yokoyama, C | 1 |
| Tsuchimochi, H | 1 |
| Schwenke, DO | 1 |
| Shimouchi, A | 1 |
| Kangawa, K | 1 |
| Tanabe, T | 1 |
| Ciccone, CD | 1 |
| Zambraski, EJ | 1 |
| Imaizumi, T | 1 |
| Takeshita, A | 1 |
| Ashihara, T | 1 |
| Nakamura, M | 1 |
| Sirén, AL | 1 |
| Weber, PC | 1 |
| Scherer, B | 1 |
| Siess, W | 1 |
| Held, E | 1 |
| Schnermann, J | 1 |
| Chrysant, SG | 2 |
| Mandal, AK | 1 |
| Nordquist, JA | 1 |
| Takase, H | 1 |
| Dohi, Y | 1 |
| Kojima, M | 1 |
| Sato, K | 1 |
| Schricker, K | 1 |
| Hamann, M | 1 |
| Kaissling, B | 1 |
| Kurtz, A | 1 |
| Martínez, FJ | 1 |
| Villa, E | 1 |
| García-Robles, R | 1 |
| Romero, JC | 2 |
| Hu, L | 1 |
| Manning, RD | 1 |
| Brands, MW | 1 |
| Munoz-Garcia, R | 1 |
| Maeso, R | 1 |
| Rodrigo, E | 1 |
| Navarro, J | 1 |
| Ruilope, LM | 1 |
| Casal, MC | 1 |
| Cachofeiro, V | 1 |
| Lahera, V | 1 |
| Krier, JD | 1 |
| Cadnapaphornchai, P | 1 |
| Aisenbrey, G | 1 |
| McDonald, KM | 1 |
| Burke, TJ | 1 |
| Schrier, RW | 1 |
| Tobian, L | 1 |
| O'Donnell, M | 1 |
| Ganguli, M | 1 |
| Levy, JV | 1 |
| Luthin, DR | 1 |
| Cline, WH | 1 |
| Hui, R | 1 |
| Falardeau, P | 2 |
| Martineau, A | 1 |
| Woods, LL | 1 |
| Roman, RJ | 1 |
| Kaldunski, ML | 1 |
| Mattson, DL | 1 |
| Mistry, M | 1 |
| Nasjletti, A | 1 |
1 review available for meclofenamic acid and Blood Pressure, High
| Article | Year |
|---|---|
Prostaglandin I2 and glucocorticoid-induced rise in arterial pressure in the rat.
Topics: Animals; Arachidonic Acids; Blood Pressure; Dexamethasone; Epoprostenol; Hypertension; Male; Meclofe | 1989 |
20 other studies available for meclofenamic acid and Blood Pressure, High
| Article | Year |
|---|---|
Alpha2-adrenoreceptor mediated sympathoinhibition of heart rate during acute hypoxia is diminished in conscious prostacyclin synthase deficient mice.
Topics: Acute Disease; Adrenergic alpha-Antagonists; Animals; Blood Pressure; Cyclooxygenase Inhibitors; Cyt | 2007 |
Effects of phenoxybenzamine, metoprolol, captopril, and meclofenamate on cardiovascular function in deoxycorticosterone acetate hypertensive Yucatan miniature swine.
Topics: Animals; Blood Pressure; Captopril; Desoxycorticosterone; Female; Heart Rate; Hemodynamics; Hyperten | 1983 |
Salt loading augments vascular responses to indomethacin in stroke-prone SHR.
Topics: Alprostadil; Animals; Blood Pressure; Bradykinin; Drinking; Hypertension; Indomethacin; Meclofenamic | 1982 |
Differences in the central actions of arachidonic acid and prostaglandin F2 alpha between spontaneously hypertensive and normotensive rats.
Topics: Animals; Arachidonic Acids; Blood Pressure; Body Temperature; Dinoprost; Dose-Response Relationship, | 1982 |
Possible significance of renal prostaglandins for renin release and blood pressure control.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Animals; Arachidonic Acids; Blood Pressure; Carbazoles; Feedback; H | 1980 |
Renal functional and organic changes induced by salt and prostaglandin inhibition in spontaneously hypertensive rats.
Topics: Animals; Blood Pressure; Glomerular Filtration Rate; Hemodynamics; Hypertension; Kidney; Male; Meclo | 1980 |
Changes in the endothelial cyclooxygenase pathway in resistance arteries of spontaneously hypertensive rats.
Topics: Acetylcholine; Adenosine; Animals; Endothelium, Vascular; Hypertension; In Vitro Techniques; Male; M | 1994 |
Renal autacoids are involved in the stimulation of renin gene expression by low perfusion pressure.
Topics: Animals; Arginine; Blood Pressure; Drug Combinations; Gene Expression; Hypertension; Kidney; Male; M | 1994 |
Effect of nitric oxide and prostaglandins on renal function in insulin-resistant hypertensive dogs.
Topics: Acetylcholine; Animals; Arginine; Disease Models, Animal; Diuresis; Dogs; Fructose; Glomerular Filtr | 1993 |
Long-term cardiovascular role of nitric oxide in conscious rats.
Topics: Animals; Arginine; Blood Pressure; Dose-Response Relationship, Drug; Heart Rate; Hypertension; Kidne | 1994 |
Acute renal excretory actions of losartan in spontaneously hypertensive rats: role of AT2 receptors, prostaglandins, kinins and nitric oxide.
Topics: Adrenergic beta-Antagonists; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Bip | 1995 |
Systemic inhibition of nitric oxide and prostaglandins in volume-induced natriuresis and hypertension.
Topics: Animals; Blood Pressure; Body Weight; Cyclooxygenase Inhibitors; Diuresis; Dogs; Drug Interactions; | 1998 |
Effects of high salt intake and meclofenamate on arterial pressure and renal function in the spontaneously hypertensive rat.
Topics: Animals; Arteries; Blood Pressure; Glomerular Filtration Rate; Hypertension; Kidney; Male; Meclofena | 1979 |
Prostaglandin-mediated hyperemia and renin-mediated hypertension during acute ureteral obstruction.
Topics: Acute Disease; Angiotensin II; Animals; Dogs; Female; Hyperemia; Hypertension; Indomethacin; Kidney; | 1978 |
Relationship of prostaglandins and sodium in renal papilla in Kyoto hypertensive rats and during high sodium diets.
Topics: Age Factors; Animals; Diet; Hypertension; Indomethacin; Kidney Medulla; Meclofenamic Acid; Prostagla | 1978 |
Changes in systolic arterial blood pressure in normal and spontaneously hypertensive rats produced by acute administration of inhibitors of prostaglandin biosynthesis.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Animals; Benzothiazoles; Blood Pressure; Fenoprofen; Hypertension; | 1977 |
Evidence for enhanced inhibitory modulation by cyclooxygenase products of noradrenergic neurotransmission in the mesenteric vasculature of young spontaneously hypertensive rats.
Topics: Animals; Blood Pressure; Cocaine; Cyclooxygenase Inhibitors; Heart Rate; Hypertension; Indomethacin; | 1991 |
Resistance of the renal biosynthesis of prostaglandin E2 to the inhibitory effect of indomethacin in the rat in vivo.
Topics: Alprostadil; Animals; Circadian Rhythm; Dose-Response Relationship, Drug; Drug Resistance; Epoproste | 1990 |
Importance of prostaglandins in hypertension during reduced uteroplacental perfusion pressure.
Topics: Animals; Blood Pressure; Bridged Bicyclo Compounds, Heterocyclic; Dogs; Fatty Acids, Unsaturated; Fe | 1989 |
Influence of eicosanoids on renal function of DOCA-salt hypertensive rats.
Topics: Animals; Benzofurans; Body Water; Bridged Bicyclo Compounds, Heterocyclic; Desoxycorticosterone; Fat | 1988 |