meclofenamic acid has been researched along with Arthritis, Rheumatoid in 14 studies
Meclofenamic Acid: A non-steroidal anti-inflammatory agent with antipyretic and antigranulation activities. It also inhibits prostaglandin biosynthesis.
meclofenamic acid : An aminobenzoic acid that is anthranilic acid in which one of the hydrogens attached to the nitrogen is replaced by a 2,6-dichloro-3-methylphenyl group. A non-steroidal anti-inflammatory drug, it is used as the sodium salt for the treatment of dysmenorrhoea (painful periods), osteoarthritis and rheumatoid arthritis.
Arthritis, Rheumatoid: A chronic systemic disease, primarily of the joints, marked by inflammatory changes in the synovial membranes and articular structures, widespread fibrinoid degeneration of the collagen fibers in mesenchymal tissues, and by atrophy and rarefaction of bony structures. Etiology is unknown, but autoimmune mechanisms have been implicated.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Forty patients with active rheumatoid arthritis were entered into a single-blind study of 12-weeks' duration to compare the efficacy and tolerance of 100 mg sodium meclofenamate 3-times daily and 250 mg naproxen twice daily." | 9.05 | Clinical therapeutic trial of sodium meclofenamate and naproxen in rheumatoid arthritis, with comments on the use of placebos in clinical trials. ( Buchanan, WW; Grace, EM; Mewa, A; Rooney, PJ, 1983) |
| "A double-blind crossover study was conducted in 15 patients with classical definite rheumatoid arthritis to compare the effect of sodium meclofenamate (300 mg daily) with placebo and indomethacin (100 mg daily)." | 9.04 | Comparison of sodium meclofenamate and indomethacin in rheumatoid arthritis. ( El-Ghobarey, AF; MacLeod, MM; Rennie, JA; Reynolds, PN, 1977) |
| "Forty patients with active rheumatoid arthritis were entered into a single-blind study of 12-weeks' duration to compare the efficacy and tolerance of 100 mg sodium meclofenamate 3-times daily and 250 mg naproxen twice daily." | 5.05 | Clinical therapeutic trial of sodium meclofenamate and naproxen in rheumatoid arthritis, with comments on the use of placebos in clinical trials. ( Buchanan, WW; Grace, EM; Mewa, A; Rooney, PJ, 1983) |
| "A double-blind crossover study was conducted in 15 patients with classical definite rheumatoid arthritis to compare the effect of sodium meclofenamate (300 mg daily) with placebo and indomethacin (100 mg daily)." | 5.04 | Comparison of sodium meclofenamate and indomethacin in rheumatoid arthritis. ( El-Ghobarey, AF; MacLeod, MM; Rennie, JA; Reynolds, PN, 1977) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 13 (92.86) | 18.7374 |
| 1990's | 1 (7.14) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Grace, EM | 1 |
| Mewa, A | 1 |
| Rooney, PJ | 1 |
| Buchanan, WW | 1 |
| Petrick, TJ | 1 |
| Black, ME | 1 |
| Dunky, A | 1 |
| Mattern, H | 1 |
| Eberl, R | 1 |
| Palmer, DG | 1 |
| Barbezat, GO | 1 |
| Gibbins, BL | 1 |
| Grennan, DM | 1 |
| Lum, J | 1 |
| Myers, DB | 1 |
| Wilson, K | 1 |
| Gowans, JD | 1 |
| Willkens, RF | 1 |
| Vreede, P | 1 |
| Flanagan, AD | 1 |
| Abruzzo, JL | 1 |
| Rennie, JA | 1 |
| MacLeod, MM | 1 |
| Reynolds, PN | 1 |
| El-Ghobarey, AF | 1 |
| Mullin, GT | 1 |
| Pincus, T | 1 |
| Marcum, SB | 1 |
| Callahan, LF | 1 |
| Adams, RF | 1 |
| Barber, J | 1 |
| Barth, WF | 1 |
| Gordon, GV | 1 |
| Huston, JW | 1 |
| Polk, JR | 1 |
| Whelton, JC | 1 |
| Koup, JR | 1 |
| Thomas, D | 1 |
| Tucker, E | 1 |
| Black, A | 1 |
| Ruderman, M | 1 |
| Dixon, JA | 1 |
| Kinkel, A | 1 |
9 trials available for meclofenamic acid and Arthritis, Rheumatoid
| Article | Year |
|---|---|
Clinical therapeutic trial of sodium meclofenamate and naproxen in rheumatoid arthritis, with comments on the use of placebos in clinical trials.
Topics: Adult; Aged; Arthritis, Rheumatoid; Clinical Trials as Topic; Female; Humans; Male; Meclofenamic Aci | 1983 |
Double-blind multicenter studies with meclofenamate sodium in the treatment of rheumatoid arthritis in the United States and Canada.
Topics: Adolescent; Adult; Aged; Arthritis, Rheumatoid; Canada; Clinical Trials as Topic; Double-Blind Metho | 1983 |
European double-blind multicenter study comparing meclofenamate sodium and indomethacin in the treatment of rheumatoid arthritis.
Topics: Adult; Aged; Arthritis, Rheumatoid; Clinical Trials as Topic; Double-Blind Method; Europe; Female; H | 1983 |
Meclofenamate sodium (meclomen) a new antiarthritic agent.
Topics: Arthritis, Rheumatoid; Aspirin; Clinical Trials as Topic; Humans; Indomethacin; Meclofenamic Acid; o | 1980 |
A single-blind crossover trial of the anti-inflammatory drug sodium meclofenamate and placebo, including an evaluation of hand grip and of lymphocyte responsiveness.
Topics: Adult; Aged; Arthritis, Rheumatoid; Clinical Trials as Topic; Female; Hand; Humans; Lymphocytes; Mal | 1981 |
Six-month, double-blind comparison of sodium meclofenamate ("Meclomen') with buffered aspirin in the treatment of rheumatoid arthritis.
Topics: Adrenal Cortex Hormones; Adult; Aged; Arthritis, Rheumatoid; Aspirin; Clinical Trials as Topic; Doub | 1981 |
Sodium meclofenamate ('Meclomen') in the treatment of rheumatoid arthritis: a double-blind comparison with aspirin and placebo.
Topics: Adolescent; Adult; Aged; Arthritis, Rheumatoid; Aspirin; Clinical Trials as Topic; Double-Blind Meth | 1981 |
Comparison of sodium meclofenamate and indomethacin in rheumatoid arthritis.
Topics: Adult; Aged; Arthritis, Rheumatoid; Clinical Trials as Topic; Double-Blind Method; Female; Humans; I | 1977 |
Sodium meclofenamate for rheumatoid arthritis: an early double-blind evaluation.
Topics: Adult; Aged; Arthritis, Rheumatoid; Aspirin; Clinical Trials as Topic; Drug Evaluation; Female; Huma | 1975 |
5 other studies available for meclofenamic acid and Arthritis, Rheumatoid
| Article | Year |
|---|---|
Long-term experience with meclofenamate sodium.
Topics: Adolescent; Adult; Aged; Arthritis, Rheumatoid; Female; Hip Joint; Humans; Joint Diseases; Knee Join | 1983 |
Correction: citation of paper by Dresner.
Topics: Arthritis, Rheumatoid; Humans; Meclofenamic Acid; ortho-Aminobenzoates; Osteoarthritis | 1981 |
Anti-inflammatory and antirheumatic drugs.
Topics: Anti-Inflammatory Agents; Arthritis, Rheumatoid; Meclofenamic Acid; ortho-Aminobenzoates; Osteoarthr | 1981 |
Longterm drug therapy for rheumatoid arthritis in seven rheumatology private practices: I. Nonsteroidal antiinflammatory drugs.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Aspirin; Female; Humans; Indomethaci | 1992 |
Plasma and synovial fluid meclofenamic acid concentrations in patients with rheumatoid arthritis of the knee.
Topics: Arthritis, Rheumatoid; Female; Humans; Knee Joint; Male; Meclofenamic Acid; Middle Aged; ortho-Amino | 1988 |