meclofenamic acid has been researched along with Arrhythmias, Cardiac in 4 studies
Meclofenamic Acid: A non-steroidal anti-inflammatory agent with antipyretic and antigranulation activities. It also inhibits prostaglandin biosynthesis.
meclofenamic acid : An aminobenzoic acid that is anthranilic acid in which one of the hydrogens attached to the nitrogen is replaced by a 2,6-dichloro-3-methylphenyl group. A non-steroidal anti-inflammatory drug, it is used as the sodium salt for the treatment of dysmenorrhoea (painful periods), osteoarthritis and rheumatoid arthritis.
Arrhythmias, Cardiac: Any disturbances of the normal rhythmic beating of the heart or MYOCARDIAL CONTRACTION. Cardiac arrhythmias can be classified by the abnormalities in HEART RATE, disorders of electrical impulse generation, or impulse conduction.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The intravenous administration of either aspirin, (in doses of 1 and 3 mg/kg) sodium meclofenamate (1 and 3 mg/kg) or indomethacin (1 and 3 mg/kg) markedly reduced ventricular arrhythmias (VT and VF) induced by coronary artery ligation in anaesthetised rats." | 7.67 | The effect of aspirin, indomethacin and sodium meclofenamate on coronary artery ligation arrhythmias in anaesthetized rats. ( Fagbemi, SO, 1984) |
| "The intravenous administration of either aspirin, (in doses of 1 and 3 mg/kg) sodium meclofenamate (1 and 3 mg/kg) or indomethacin (1 and 3 mg/kg) markedly reduced ventricular arrhythmias (VT and VF) induced by coronary artery ligation in anaesthetised rats." | 3.67 | The effect of aspirin, indomethacin and sodium meclofenamate on coronary artery ligation arrhythmias in anaesthetized rats. ( Fagbemi, SO, 1984) |
| "Cardiac arrhythmias are a major factor in the occurrence of morbidity and sudden death in patients with cardiovascular disease." | 1.72 | TRPM4 inhibition by meclofenamate suppresses Ca2+-dependent triggered arrhythmias. ( Hendrikx, L; Jacobs, G; Kecskés, M; Kerselaers, S; Lehnart, SE; Nilius, B; Oosterlinck, W; Philippaert, K; Pinto, S; Pironet, A; Priori, SG; Segal, A; Van Den Broeck, E; Vandewiele, F; Vennekens, R; Verelst, J; Voets, T; Wegener, J, 2022) |
| "The incidence of ventricular tachycardia was reduced from 75% to 25% (P<0." | 1.30 | Delayed protection against ventricular arrhythmias by monophosphoryl lipid-A in a canine model of ischaemia and reperfusion. ( György, K; Papp, JG; Parratt, JR; Rastegar, MA; Végh, A, 1999) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (25.00) | 18.7374 |
| 1990's | 1 (25.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 2 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Heijman, J | 1 |
| Dobrev, D | 1 |
| Vandewiele, F | 1 |
| Pironet, A | 1 |
| Jacobs, G | 1 |
| Kecskés, M | 1 |
| Wegener, J | 1 |
| Kerselaers, S | 1 |
| Hendrikx, L | 1 |
| Verelst, J | 1 |
| Philippaert, K | 1 |
| Oosterlinck, W | 1 |
| Segal, A | 1 |
| Van Den Broeck, E | 1 |
| Pinto, S | 1 |
| Priori, SG | 1 |
| Lehnart, SE | 1 |
| Nilius, B | 1 |
| Voets, T | 1 |
| Vennekens, R | 1 |
| Fagbemi, SO | 1 |
| Végh, A | 1 |
| György, K | 1 |
| Rastegar, MA | 1 |
| Papp, JG | 1 |
| Parratt, JR | 1 |
4 other studies available for meclofenamic acid and Arrhythmias, Cardiac
| Article | Year |
|---|---|
Molecular determinants and therapeutic potential of focal ectopic activity: more than meets the Iti.
Topics: Arrhythmias, Cardiac; Calcium; Humans; Meclofenamic Acid; TRPM Cation Channels | 2022 |
TRPM4 inhibition by meclofenamate suppresses Ca2+-dependent triggered arrhythmias.
Topics: Animals; Arrhythmias, Cardiac; Calcium; Meclofenamic Acid; Mice; Myocytes, Cardiac; Tachycardia, Ven | 2022 |
The effect of aspirin, indomethacin and sodium meclofenamate on coronary artery ligation arrhythmias in anaesthetized rats.
Topics: Animals; Anti-Inflammatory Agents; Arrhythmias, Cardiac; Aspirin; Coronary Vessels; Disease Models, | 1984 |
Delayed protection against ventricular arrhythmias by monophosphoryl lipid-A in a canine model of ischaemia and reperfusion.
Topics: Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Arterial Occlusive Diseases; Coronary Vessels | 1999 |