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meclofenamic acid and Anasarca

meclofenamic acid has been researched along with Anasarca in 7 studies

Meclofenamic Acid: A non-steroidal anti-inflammatory agent with antipyretic and antigranulation activities. It also inhibits prostaglandin biosynthesis.
meclofenamic acid : An aminobenzoic acid that is anthranilic acid in which one of the hydrogens attached to the nitrogen is replaced by a 2,6-dichloro-3-methylphenyl group. A non-steroidal anti-inflammatory drug, it is used as the sodium salt for the treatment of dysmenorrhoea (painful periods), osteoarthritis and rheumatoid arthritis.

Research Excerpts

ExcerptRelevanceReference
"130 patients with edema as the sequel of a traumatic incident were selected for this study, 43 patients were treated with 300 mg N-(2,6-dichloro-m-tolyl)anthranilic acid, sodium salt (meclofenamate sodium, Meclomen) per day for one week, 44 patients received 600 mg oxyphenbutazone per day and 43 patients received placebo."5.05Meclofenamate sodium in the treatment of post-traumatic edema. Report of a controlled double-blind study. ( Honorato Pérez, J; Imizcoz Barriola, JL; Martí Massó, R, 1983)
"A topical preparation of meclofenamic acid (Meclomen) was tested for anti-inflammatory activity in a murine model of carrageenan footpad oedema."3.67The topical anti-inflammatory effects of a topical preparation of meclofenamic acid on carrageenan-induced footpad swelling in mice. ( Gilbertsen, RB; Gluckman, MI; Moniot, S; Schrier, DJ, 1987)
" When dosed orally the ID50s for 5b and 10b in CFE are 8."1.291,3,4-Oxadiazole, 1,3,4-thiadiazole, and 1,2,4-triazole analogs of the fenamates: in vitro inhibition of cyclooxygenase and 5-lipoxygenase activities. ( Bornemeier, DA; Boschelli, DH; Connor, DT; Dyer, RD; Kennedy, JA; Kuipers, PJ; Okonkwo, GC; Schrier, DJ; Wright, CD, 1993)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19905 (71.43)18.7374
1990's1 (14.29)18.2507
2000's1 (14.29)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Boschelli, DH1
Connor, DT1
Bornemeier, DA1
Dyer, RD1
Kennedy, JA1
Kuipers, PJ1
Okonkwo, GC1
Schrier, DJ2
Wright, CD1
Kalgutkar, AS1
Crews, BC1
Rowlinson, SW1
Marnett, AB1
Kozak, KR1
Remmel, RP1
Marnett, LJ1
Honorato Pérez, J1
Martí Massó, R1
Imizcoz Barriola, JL1
McLean, JR1
Gluckman, MI2
Fregnan, GB2
Subissi, A1
Torsello, AL2
Moniot, S1
Gilbertsen, RB1
Brunet, S1

Trials

1 trial available for meclofenamic acid and Anasarca

ArticleYear
Meclofenamate sodium in the treatment of post-traumatic edema. Report of a controlled double-blind study.
    Arzneimittel-Forschung, 1983, Volume: 33, Issue:4A

    Topics: Adolescent; Adult; Aged; Clinical Trials as Topic; Double-Blind Method; Edema; Female; Humans; Male;

1983

Other Studies

6 other studies available for meclofenamic acid and Anasarca

ArticleYear
1,3,4-Oxadiazole, 1,3,4-thiadiazole, and 1,2,4-triazole analogs of the fenamates: in vitro inhibition of cyclooxygenase and 5-lipoxygenase activities.
    Journal of medicinal chemistry, 1993, Jun-25, Volume: 36, Issue:13

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygenase Inhibitors; Edema; In Vitro Techniq

1993
Biochemically based design of cyclooxygenase-2 (COX-2) inhibitors: facile conversion of nonsteroidal antiinflammatory drugs to potent and highly selective COX-2 inhibitors.
    Proceedings of the National Academy of Sciences of the United States of America, 2000, Jan-18, Volume: 97, Issue:2

    Topics: 5,8,11,14-Eicosatetraynoic Acid; Amides; Animals; Anti-Inflammatory Agents, Non-Steroidal; Cell Line

2000
On the mechanism of the pharmacologic activity of meclofenamate sodium.
    Arzneimittel-Forschung, 1983, Volume: 33, Issue:4A

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Edema; Fever; Humans; Meclofenamic Acid; ortho-Ami

1983
Biological properties of a new non-steroidal anti-inflammatory drug: etoclofene.
    Il Farmaco; edizione scientifica, 1975, Volume: 30, Issue:5

    Topics: Analgesics; Animals; Anti-Inflammatory Agents; Arthritis; Aspirin; Edema; Female; Guinea Pigs; Indom

1975
The topical anti-inflammatory effects of a topical preparation of meclofenamic acid on carrageenan-induced footpad swelling in mice.
    The Journal of pharmacy and pharmacology, 1987, Volume: 39, Issue:1

    Topics: Administration, Oral; Administration, Topical; Animals; Anti-Inflammatory Agents; Carrageenan; Edema

1987
Local anti-inflammatory properties of etoclofene. A new fenamate derivative.
    Pharmacology, 1974, Volume: 11, Issue:4

    Topics: Administration, Oral; Administration, Topical; Animals; Anti-Inflammatory Agents; Aspirin; Benzyl Co

1974