meclofenamic acid has been researched along with Alzheimer Disease in 1 studies
Meclofenamic Acid: A non-steroidal anti-inflammatory agent with antipyretic and antigranulation activities. It also inhibits prostaglandin biosynthesis.
meclofenamic acid : An aminobenzoic acid that is anthranilic acid in which one of the hydrogens attached to the nitrogen is replaced by a 2,6-dichloro-3-methylphenyl group. A non-steroidal anti-inflammatory drug, it is used as the sodium salt for the treatment of dysmenorrhoea (painful periods), osteoarthritis and rheumatoid arthritis.
Alzheimer Disease: A degenerative disease of the BRAIN characterized by the insidious onset of DEMENTIA. Impairment of MEMORY, judgment, attention span, and problem solving skills are followed by severe APRAXIAS and a global loss of cognitive abilities. The condition primarily occurs after age 60, and is marked pathologically by severe cortical atrophy and the triad of SENILE PLAQUES; NEUROFIBRILLARY TANGLES; and NEUROPIL THREADS. (From Adams et al., Principles of Neurology, 6th ed, pp1049-57)
| Excerpt | Relevance | Reference |
|---|---|---|
| " Thirteen of the NSAIDs and the enantiomers of flurbiprofen were then tested in acute dosing studies in amyloid beta protein precursor (APP) transgenic mice, and plasma and brain levels of Abeta and the drug were evaluated." | 1.32 | NSAIDs and enantiomers of flurbiprofen target gamma-secretase and lower Abeta 42 in vivo. ( Das, P; Eriksen, JL; Golde, TE; Jessing, KW; Koo, EH; McLendon, DC; Ozols, VV; Sagi, SA; Smith, TE; Weggen, S; Zavitz, KH, 2003) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Eriksen, JL | 1 |
| Sagi, SA | 1 |
| Smith, TE | 1 |
| Weggen, S | 1 |
| Das, P | 1 |
| McLendon, DC | 1 |
| Ozols, VV | 1 |
| Jessing, KW | 1 |
| Zavitz, KH | 1 |
| Koo, EH | 1 |
| Golde, TE | 1 |
1 other study available for meclofenamic acid and Alzheimer Disease
| Article | Year |
|---|---|
NSAIDs and enantiomers of flurbiprofen target gamma-secretase and lower Abeta 42 in vivo.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid Precursor Protein Secretases; Animals; Anti-Inflam | 2003 |