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meclizine and Motion Sickness

meclizine has been researched along with Motion Sickness in 28 studies

Meclizine: A histamine H1 antagonist used in the treatment of motion sickness, vertigo, and nausea during pregnancy and radiation sickness.

Motion Sickness: Disorder caused by motion. It includes sea sickness, train sickness, roller coaster rides, rocking chair, hammock swing, car sickness, air sickness, or SPACE MOTION SICKNESS. Symptoms include nausea, vomiting and/or dizziness.

Research Excerpts

ExcerptRelevanceReference
"The efficacy of transdermal scopolamine, oral meclizine, and placebo in protection against motion sickness was compared in a double-blind crossover study."7.67Transdermal scopolamine, oral meclizine, and placebo in motion sickness. ( Dahl, E; Lillevold, PE; Offer-Ohlsen, D; Sandvik, L, 1984)
"The meclizine group had lower VNRS scores in the PACU at 15 (P = ."6.73Meclizine in combination with ondansetron for prevention of postoperative nausea and vomiting in a high-risk population. ( Benfield, DA; Forrester, CM; Kelly, JA; Matern, CE; Pellegrini, JE, 2007)
"Meclizine, an antihistamine, has been widely used for prophylactic treatment and management of motion sickness."5.16Meclizine metabolism and pharmacokinetics: formulation on its absorption. ( Chow, MS; Lee, B; Pearce, D; Qian, S; Wang, Y; Wang, Z; Zhang, Q, 2012)
"The findings indicated that only the combination of promethazine + caffeine showed a statistically significant reduction in nausea and motion sickness severity, and an improvement in reaction time when compared with its placebo control."5.12Airsickness prevention in helicopter passengers. ( Curry, IP; Estrada, A; Fuller, DR; LeDuc, PA; Phelps, SE, 2007)
"12 neurologically normal adults were tested before and after administration of meclizine, an over-the-counter medication for motion sickness."3.70Physiological and behavioral effects of an antivertigo antihistamine in adults. ( Lauter, JL; Lynch, O; Schoeffler, L; Wood, SB, 1999)
" These cases were selected from a prior quantitative study in which three antihistamines (meclizine, cyclizine, dimenhydrinate) and three stimulants (pemoline, methylphenidate, dextroamphetamine) were tested in variable combinations (using a specific clinical method) for favorable responses by 100 children characterized by diagnostic evidence of learning disabilities and cerebellar-vestibular dysfunctioning."3.68Dramatic favorable responses of children with learning disabilities or dyslexia and attention deficit disorder to antimotion sickness medications: four case reports. ( Levinson, HN, 1991)
"The efficacy of transdermal scopolamine, oral meclizine, and placebo in protection against motion sickness was compared in a double-blind crossover study."3.67Transdermal scopolamine, oral meclizine, and placebo in motion sickness. ( Dahl, E; Lillevold, PE; Offer-Ohlsen, D; Sandvik, L, 1984)
"The meclizine group had lower VNRS scores in the PACU at 15 (P = ."2.73Meclizine in combination with ondansetron for prevention of postoperative nausea and vomiting in a high-risk population. ( Benfield, DA; Forrester, CM; Kelly, JA; Matern, CE; Pellegrini, JE, 2007)
"The case of a patient who treated withdrawal symptoms from trans-dermal scopolamine with meclizine is reported."1.35Withdrawal symptoms after discontinuation of transdermal scopolamine therapy: treatment with meclizine. ( Ezzo, DC; Patel, PN, 2009)

Research

Studies (28)

TimeframeStudies, this research(%)All Research%
pre-199017 (60.71)18.7374
1990's4 (14.29)18.2507
2000's4 (14.29)29.6817
2010's2 (7.14)24.3611
2020's1 (3.57)2.80

Authors

AuthorsStudies
Wibble, T1
Engström, J1
Verrecchia, L1
Pansell, T1
UNGER, HR1
MILCH, LJ1
Banting, J1
Meriano, T1
Patel, PN1
Ezzo, DC1
Wang, Z1
Lee, B1
Pearce, D1
Qian, S1
Wang, Y1
Zhang, Q1
Chow, MS1
RICHARDS, AB1
HUGHES, FW1
FORNEY, RB1
KAPLAN, I1
WOOD, CD6
GRAYBIEL, A7
MCDONOUGH, RG1
KENNEDY, RS2
OOSTERVELD, WJ1
LOOMIS, GR1
Paul, MA1
MacLellan, M1
Gray, G1
Forrester, CM1
Benfield, DA1
Matern, CE1
Kelly, JA1
Pellegrini, JE1
Estrada, A1
LeDuc, PA1
Curry, IP1
Phelps, SE1
Fuller, DR1
Deane, FR1
Brand, JJ1
Becker, G2
Goossens, H1
Seemann, K1
Souchon, F1
Weitz, T1
Dahl, E1
Offer-Ohlsen, D1
Lillevold, PE1
Sandvik, L1
Murray, JB1
Lauter, JL1
Lynch, O1
Wood, SB1
Schoeffler, L1
Knepton, J1
Levinson, HN1
Oenbrink, RJ1
Manno, JE1
Manno, BR1
Redetzki, HM1
Wood, MJ1
Mims, ME1
Kennedy, RE1
McDonough, RB1

Reviews

2 reviews available for meclizine and Motion Sickness

ArticleYear
Sea State Green.
    Journal of special operations medicine : a peer reviewed journal for SOF medical professionals, 2016,summer, Volume: 16, Issue:2

    Topics: Acupressure; Antiemetics; Cholinergic Antagonists; Dopamine Antagonists; Emergency Medical Technicia

2016
Psychophysiological aspects of motion sickness.
    Perceptual and motor skills, 1997, Volume: 85, Issue:3 Pt 2

    Topics: Administration, Cutaneous; Dextroamphetamine; Histamine H1 Antagonists; Humans; Meclizine; Motion Si

1997

Trials

12 trials available for meclizine and Motion Sickness

ArticleYear
The effects of meclizine on motion sickness revisited.
    British journal of clinical pharmacology, 2020, Volume: 86, Issue:8

    Topics: Eye Movements; Humans; Meclizine; Motion Sickness

2020
Meclizine metabolism and pharmacokinetics: formulation on its absorption.
    Journal of clinical pharmacology, 2012, Volume: 52, Issue:9

    Topics: Absorption; Adult; Area Under Curve; Biological Availability; Chemistry, Pharmaceutical; Cross-Over

2012
Motion-sickness medications for aircrew: impact on psychomotor performance.
    Aviation, space, and environmental medicine, 2005, Volume: 76, Issue:6

    Topics: Adult; Aerospace Medicine; Aircraft; Antiemetics; Canada; Dimenhydrinate; Female; Humans; Male; Mecl

2005
Meclizine in combination with ondansetron for prevention of postoperative nausea and vomiting in a high-risk population.
    AANA journal, 2007, Volume: 75, Issue:1

    Topics: Adult; Drug Therapy, Combination; Elective Surgical Procedures; Female; Humans; Male; Meclizine; Mid

2007
Airsickness prevention in helicopter passengers.
    Aviation, space, and environmental medicine, 2007, Volume: 78, Issue:4

    Topics: Acoustic Stimulation; Adolescent; Adult; Aircraft; Antiemetics; Health Surveys; Humans; Male; Mecliz

2007
Effect of drugs in altering susceptibility to motion sickness in aerobatics and the slow rotation room.
    Aerospace medicine, 1967, Volume: 38, Issue:8

    Topics: Adolescent; Adult; Aerospace Medicine; Antiemetics; Cyclizine; Dextroamphetamine; Humans; Male; Mecl

1967
[Prevention of motion sickness with a transdermal therapeutic system containing scopolamine. A randomized, comparative double-blind study in the German Federal Navy].
    Deutsche medizinische Wochenschrift (1946), 1984, Dec-07, Volume: 109, Issue:49

    Topics: Administration, Topical; Adolescent; Adult; Double-Blind Method; Humans; Male; Meclizine; Motion Sic

1984
Evaluation of a new antinauseant drug for the prevention of motion sickness.
    Aviation, space, and environmental medicine, 1977, Volume: 48, Issue:9

    Topics: Administration, Oral; Adolescent; Adult; Antiemetics; Clinical Trials as Topic; Dose-Response Relati

1977
Evaluation of antimotion sickness drug side effects on performance.
    Aviation, space, and environmental medicine, 1985, Volume: 56, Issue:4

    Topics: Adolescent; Adult; Aerospace Medicine; Arousal; Clinical Trials as Topic; Cyclizine; Dextroamphetami

1985
Evaluation of sixteen anti-motion sickness drugs under controlled laboratory conditions.
    Aerospace medicine, 1968, Volume: 39, Issue:12

    Topics: Adolescent; Adult; Amphetamine; Antiemetics; Benzamides; Chlorpromazine; Clinical Trials as Topic; C

1968
A comparison of effectiveness of some antimotion sickness drugs using recommended and larger than recommended doses as tested in the slow rotation room. NSAM-945.
    Research report. Naval School of Aviation Medicine (U.S.), 1965

    Topics: Benzamides; Clinical Trials as Topic; Dextroamphetamine; Humans; Male; Meclizine; Motion Sickness; P

1965
Side effects of some antimotion sickness drugs as measured by psychomotor test and questionnaires.
    Aerospace medicine, 1966, Volume: 37, Issue:4

    Topics: Amphetamine; Benzamides; Chlorpromazine; Humans; Male; Meclizine; Motion Sickness; Placebos; Psychol

1966

Other Studies

14 other studies available for meclizine and Motion Sickness

ArticleYear
The efficacy of trilafon in potentiating bonamine motion sickness prophylaxis in dogs.
    Project report. USAF School of Aviation Medicine, 1959, Volume: 59, Issue:78

    Topics: Animals; Anti-Allergic Agents; Dogs; Histamine H1 Antagonists; Meclizine; Motion Sickness; Perphenaz

1959
Withdrawal symptoms after discontinuation of transdermal scopolamine therapy: treatment with meclizine.
    American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists, 2009, Nov-15, Volume: 66, Issue:22

    Topics: Administration, Cutaneous; Adult; Antiemetics; Female; Humans; Meclizine; Motion Sickness; Muscarini

2009
EVALUATION OF ANTI-MOTION SICKNESS DRUGS BY COMPONENT MEASUREMENTS OF NYSTAGMUS IN GUINEA PIGS.
    Current therapeutic research, clinical and experimental, 1963, Volume: 5

    Topics: Cyclizine; Dimenhydrinate; Electrodiagnosis; Guinea Pigs; Meclizine; Motion Sickness; Nystagmus, Pat

1963
MOTION SICKNESS ON RAILROADS.
    Industrial medicine & surgery, 1964, Volume: 33

    Topics: Benzamides; Child; Dimenhydrinate; Drug Therapy; Humans; Meclizine; Motion Sickness; Railroads; Stat

1964
EVALUATION OF SOME ANTIMOTION SICKNESS DRUGS ON THE SLOW ROTATION ROOM (NO. 1). NSAM-922.
    Research report. Naval School of Aviation Medicine (U.S.), 1965, Volume: 15

    Topics: Biomedical Research; Dextroamphetamine; Drug Therapy; Humans; Meclizine; Motion Sickness; Pharmacolo

1965
[THE ACTION OF 2 DRUGS FOR SEASICKNESS, ASSESSED FOR THEIR EFFECT ON VESTIBULAR EYE MOVEMENTS].
    Nederlands tijdschrift voor geneeskunde, 1965, May-01, Volume: 109

    Topics: Eye Movements; Histamine H1 Antagonists; Humans; Meclizine; Motion Sickness; Nystagmus, Pathologic

1965
Evaluation of meclizine hydrochloride in prevention of seasickness.
    Military medicine, 1955, Volume: 117, Issue:1

    Topics: Biomedical Research; Histamine H1 Antagonists; Humans; Meclizine; Motion Sickness

1955
Motion sickness and its prevention by drugs.
    Current medicine and drugs, 1967, Volume: 7, Issue:12

    Topics: Cyclizine; Diphenhydramine; Ear, Inner; Humans; Meclizine; Motion Sickness; Promethazine; Scopolamin

1967
Transdermal scopolamine, oral meclizine, and placebo in motion sickness.
    Clinical pharmacology and therapeutics, 1984, Volume: 36, Issue:1

    Topics: Administration, Oral; Adult; Double-Blind Method; Female; Humans; Male; Meclizine; Motion Sickness;

1984
Physiological and behavioral effects of an antivertigo antihistamine in adults.
    Perceptual and motor skills, 1999, Volume: 88, Issue:3 Pt 1

    Topics: Adult; Attention; Auditory Cortex; Auditory Perception; Electroencephalography; Evoked Potentials, A

1999
Prevention and treatment of space sickness in shuttle-orbiter missions.
    Aviation, space, and environmental medicine, 1979, Volume: 50, Issue:2

    Topics: Adult; Delayed-Action Preparations; Dimenhydrinate; Drug Combinations; Ephedrine; Humans; Meclizine;

1979
Dramatic favorable responses of children with learning disabilities or dyslexia and attention deficit disorder to antimotion sickness medications: four case reports.
    Perceptual and motor skills, 1991, Volume: 73, Issue:3 Pt 1

    Topics: Attention Deficit Disorder with Hyperactivity; Central Nervous System Stimulants; Child; Cyclizine;

1991
Another approach to motion sickness.
    Postgraduate medicine, 1991, Nov-01, Volume: 90, Issue:6

    Topics: Humans; Meclizine; Motion Sickness; Promethazine; Travel

1991
[Transdermally applied scopolamine for continuous prevention of motion sickness. Revival of a 150-year-old method].
    Schweizerische Rundschau fur Medizin Praxis = Revue suisse de medecine Praxis, 1985, Mar-12, Volume: 74, Issue:11

    Topics: Administration, Topical; Adult; Antiemetics; Double-Blind Method; Female; History, 15th Century; His

1985