Page last updated: 2024-10-30

meclizine and Edema

meclizine has been researched along with Edema in 5 studies

Meclizine: A histamine H1 antagonist used in the treatment of motion sickness, vertigo, and nausea during pregnancy and radiation sickness.

Edema: Abnormal fluid accumulation in TISSUES or body cavities. Most cases of edema are present under the SKIN in SUBCUTANEOUS TISSUE.

Research Excerpts

ExcerptRelevanceReference
"Paw edema was induced with DvL in control animals, and in animals pretreated with glucocorticoid or with blockers of histamine, nitric oxide synthase, cyclooxygenase, platelet activating factor (PAF), bradykinin and lipoxygenase."3.79Neutrophil-infiltrated paw edema induced by mannose-binding Dioclea violacea lectin. ( Assreuy, AM; Cavada, BS; de Alencar, NM; do Nascimento, KS; Martins, JL; Mota, MR; Rodrigues, NV, 2013)
" The antihistamine meclizine and the mixed anti histamine/anti-5-HT antagonist cyproheptadine reduced the anaphylactic reaction by 55 and 84% respectively, in non-boosted animals and were less effective against edema induced by 1 microgram antigen in boosted animals."3.68Interference of antihistamines and anti-allergic drugs with antigen-induced paw edema in boosted and unboosted mice. ( Amorim, CZ; Cordeiro, RS; Vargaftig, BB, 1992)
" The edematogenic reaction appeared 5 min after the intraplantar injection of ovalbumin, peaked at 30 min after the antigenic challenge, and decreased thereafter."3.68Effect of PAF-acether antagonists on active anaphylactic mouse paw edema. ( Amorim, CZ; Cordeiro, RS; Henriques, MG; Vargaftig, BB; Weg, VB, 1991)
"The ability of allergens to induce hyperalgesia in immunoglobulin E (IgE)-sensitized rats was investigated."1.32Combined action of vasoactive amines and bradykinin mediates allergen-evoked thermal hyperalgesia in rats. ( Calixto, JB; Cordeiro, RS; e Silva, PM; Lavich, TR; Martins, MA, 2003)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (60.00)18.2507
2000's1 (20.00)29.6817
2010's1 (20.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
de Alencar, NM1
Mota, MR1
Rodrigues, NV1
Martins, JL1
do Nascimento, KS1
Assreuy, AM1
Cavada, BS1
Lavich, TR1
Cordeiro, RS4
Calixto, JB1
e Silva, PM1
Martins, MA2
Amorim, CZ2
Vargaftig, BB2
Henriques, MG1
Weg, VB1
Castro-Faria-Neto, HC1
Bozza, PT1
Perez, SA1
Correa-Da-Silva, AC1
Lima, MC1
Cruz, HN1
Sousa, MV1
Morhy, L1

Other Studies

5 other studies available for meclizine and Edema

ArticleYear
Neutrophil-infiltrated paw edema induced by mannose-binding Dioclea violacea lectin.
    Pharmacological reports : PR, 2013, Volume: 65, Issue:1

    Topics: Animals; Anti-Inflammatory Agents; Binding Sites; Cytokines; Dexamethasone; Dioclea; Disease Models,

2013
Combined action of vasoactive amines and bradykinin mediates allergen-evoked thermal hyperalgesia in rats.
    European journal of pharmacology, 2003, Feb-21, Volume: 462, Issue:1-3

    Topics: Allergens; Animals; Bradykinin; Bradykinin Receptor Antagonists; Cyproheptadine; Dinitrophenols; Dos

2003
Interference of antihistamines and anti-allergic drugs with antigen-induced paw edema in boosted and unboosted mice.
    European journal of pharmacology, 1992, Jun-17, Volume: 216, Issue:3

    Topics: Analysis of Variance; Anaphylaxis; Animals; Drug Interactions; Edema; Histamine H1 Antagonists; Immu

1992
Effect of PAF-acether antagonists on active anaphylactic mouse paw edema.
    Lipids, 1991, Volume: 26, Issue:12

    Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Acetophenones; Anaphylaxis; Animals; A

1991
Pro-inflammatory activity of enterolobin: a haemolytic protein purified from seeds of the Brazilian tree Enterolobium contortisiliquum.
    Toxicon : official journal of the International Society on Toxinology, 1991, Volume: 29, Issue:9

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygenase Inhibitors; Dose-Response Relations

1991