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meclizine and Disease Models, Animal

meclizine has been researched along with Disease Models, Animal in 9 studies

Meclizine: A histamine H1 antagonist used in the treatment of motion sickness, vertigo, and nausea during pregnancy and radiation sickness.

Disease Models, Animal: Naturally-occurring or experimentally-induced animal diseases with pathological processes analogous to human diseases.

Research Excerpts

ExcerptRelevanceReference
" Dementia was induced in mice by intacerebroventricular administration of streptozotocin (STZ) followed by treatment with meclizine, a PXR agonist, and subsequently exposed to the Morris water maze test and biochemical and histopathological analysis to evaluate the effect on cognition."7.96Meclizine ameliorates memory deficits in streptozotocin-induced experimental dementia in mice: role of nuclear pregnane X receptors. ( Chahal, SK; Madan, J; Singh, H; Sodhi, RK, 2020)
" Dementia was induced in mice by intacerebroventricular administration of streptozotocin (STZ) followed by treatment with meclizine, a PXR agonist, and subsequently exposed to the Morris water maze test and biochemical and histopathological analysis to evaluate the effect on cognition."3.96Meclizine ameliorates memory deficits in streptozotocin-induced experimental dementia in mice: role of nuclear pregnane X receptors. ( Chahal, SK; Madan, J; Singh, H; Sodhi, RK, 2020)
"Paw edema was induced with DvL in control animals, and in animals pretreated with glucocorticoid or with blockers of histamine, nitric oxide synthase, cyclooxygenase, platelet activating factor (PAF), bradykinin and lipoxygenase."3.79Neutrophil-infiltrated paw edema induced by mannose-binding Dioclea violacea lectin. ( Assreuy, AM; Cavada, BS; de Alencar, NM; do Nascimento, KS; Martins, JL; Mota, MR; Rodrigues, NV, 2013)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19901 (11.11)18.7374
1990's0 (0.00)18.2507
2000's1 (11.11)29.6817
2010's4 (44.44)24.3611
2020's3 (33.33)2.80

Authors

AuthorsStudies
Abrams, RPM1
Yasgar, A1
Teramoto, T1
Lee, MH1
Dorjsuren, D1
Eastman, RT1
Malik, N1
Zakharov, AV1
Li, W1
Bachani, M1
Brimacombe, K1
Steiner, JP1
Hall, MD1
Balasubramanian, A1
Jadhav, A1
Padmanabhan, R1
Simeonov, A1
Nath, A1
Jang, EH2
Bae, HD2
Jeon, Y2
Shin, DH2
Kang, S2
Lee, K2
Singh, H1
Sodhi, RK1
Chahal, SK1
Madan, J1
Matsushita, M1
Esaki, R1
Mishima, K1
Ishiguro, N1
Ohno, K1
Kitoh, H1
de Alencar, NM1
Mota, MR1
Rodrigues, NV1
Martins, JL1
do Nascimento, KS1
Assreuy, AM1
Cavada, BS1
Kishi, S1
Campanholle, G1
Gohil, VM2
Perocchi, F1
Brooks, CR1
Morizane, R1
Sabbisetti, V1
Ichimura, T1
Mootha, VK2
Bonventre, JV1
Offner, N1
Walker, JA1
Sheth, SA1
Fossale, E1
Gusella, JF1
MacDonald, ME1
Neri, C1
Källén, B1
Mottet, I1
Morgan, PR1

Other Studies

9 other studies available for meclizine and Disease Models, Animal

ArticleYear
Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors.
    Proceedings of the National Academy of Sciences of the United States of America, 2020, 12-08, Volume: 117, Issue:49

    Topics: Animals; Antiviral Agents; Artificial Intelligence; Chlorocebus aethiops; Disease Models, Animal; Dr

2020
Meclizine, a piperazine-derivative antihistamine, binds to dimerized translationally controlled tumor protein and attenuates allergic reactions in a mouse model.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2023, Volume: 157

    Topics: Animals; Biomarkers, Tumor; Disease Models, Animal; Histamine Antagonists; Hypersensitivity; Meclizi

2023
Meclizine, a piperazine-derivative antihistamine, binds to dimerized translationally controlled tumor protein and attenuates allergic reactions in a mouse model.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2023, Volume: 157

    Topics: Animals; Biomarkers, Tumor; Disease Models, Animal; Histamine Antagonists; Hypersensitivity; Meclizi

2023
Meclizine, a piperazine-derivative antihistamine, binds to dimerized translationally controlled tumor protein and attenuates allergic reactions in a mouse model.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2023, Volume: 157

    Topics: Animals; Biomarkers, Tumor; Disease Models, Animal; Histamine Antagonists; Hypersensitivity; Meclizi

2023
Meclizine, a piperazine-derivative antihistamine, binds to dimerized translationally controlled tumor protein and attenuates allergic reactions in a mouse model.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2023, Volume: 157

    Topics: Animals; Biomarkers, Tumor; Disease Models, Animal; Histamine Antagonists; Hypersensitivity; Meclizi

2023
Meclizine ameliorates memory deficits in streptozotocin-induced experimental dementia in mice: role of nuclear pregnane X receptors.
    Canadian journal of physiology and pharmacology, 2020, Volume: 98, Issue:6

    Topics: Animals; Brain; Dementia; Disease Models, Animal; Female; Glutathione; Interleukin-1beta; Male; Mecl

2020
Clinical dosage of meclozine promotes longitudinal bone growth, bone volume, and trabecular bone quality in transgenic mice with achondroplasia.
    Scientific reports, 2017, 08-07, Volume: 7, Issue:1

    Topics: Achondroplasia; Animals; Bone and Bones; Bone Development; Cancellous Bone; Disease Models, Animal;

2017
Neutrophil-infiltrated paw edema induced by mannose-binding Dioclea violacea lectin.
    Pharmacological reports : PR, 2013, Volume: 65, Issue:1

    Topics: Animals; Anti-Inflammatory Agents; Binding Sites; Cytokines; Dexamethasone; Dioclea; Disease Models,

2013
Meclizine Preconditioning Protects the Kidney Against Ischemia-Reperfusion Injury.
    EBioMedicine, 2015, Volume: 2, Issue:9

    Topics: Acute Kidney Injury; Adenosine Triphosphate; Animals; Cell Respiration; Cytochromes c; Deoxyglucose;

2015
Meclizine is neuroprotective in models of Huntington's disease.
    Human molecular genetics, 2011, Jan-15, Volume: 20, Issue:2

    Topics: Animals; Apoptosis; Caenorhabditis elegans; Cell Respiration; Disease Models, Animal; Drosophila mel

2011
Delivery outcome after the use of meclozine in early pregnancy.
    European journal of epidemiology, 2003, Volume: 18, Issue:7

    Topics: Abnormalities, Drug-Induced; Adolescent; Adult; Animals; Antiemetics; Body Mass Index; Disease Model

2003
The fate of the expected fusion zone in rat fetuses with experimentally-induced cleft palate - an ultrastructural study.
    Developmental biology, 1976, Jul-15, Volume: 51, Issue:2

    Topics: Animals; Cleft Palate; Disease Models, Animal; Epithelium; Female; Gestational Age; Meclizine; Palat

1976