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meclizine and Dementia

meclizine has been researched along with Dementia in 1 studies

Meclizine: A histamine H1 antagonist used in the treatment of motion sickness, vertigo, and nausea during pregnancy and radiation sickness.

Dementia: An acquired organic mental disorder with loss of intellectual abilities of sufficient severity to interfere with social or occupational functioning. The dysfunction is multifaceted and involves memory, behavior, personality, judgment, attention, spatial relations, language, abstract thought, and other executive functions. The intellectual decline is usually progressive, and initially spares the level of consciousness.

Research Excerpts

ExcerptRelevanceReference
" Dementia was induced in mice by intacerebroventricular administration of streptozotocin (STZ) followed by treatment with meclizine, a PXR agonist, and subsequently exposed to the Morris water maze test and biochemical and histopathological analysis to evaluate the effect on cognition."7.96Meclizine ameliorates memory deficits in streptozotocin-induced experimental dementia in mice: role of nuclear pregnane X receptors. ( Chahal, SK; Madan, J; Singh, H; Sodhi, RK, 2020)
" Dementia was induced in mice by intacerebroventricular administration of streptozotocin (STZ) followed by treatment with meclizine, a PXR agonist, and subsequently exposed to the Morris water maze test and biochemical and histopathological analysis to evaluate the effect on cognition."3.96Meclizine ameliorates memory deficits in streptozotocin-induced experimental dementia in mice: role of nuclear pregnane X receptors. ( Chahal, SK; Madan, J; Singh, H; Sodhi, RK, 2020)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's1 (100.00)2.80

Authors

AuthorsStudies
Singh, H1
Sodhi, RK1
Chahal, SK1
Madan, J1

Other Studies

1 other study available for meclizine and Dementia

ArticleYear
Meclizine ameliorates memory deficits in streptozotocin-induced experimental dementia in mice: role of nuclear pregnane X receptors.
    Canadian journal of physiology and pharmacology, 2020, Volume: 98, Issue:6

    Topics: Animals; Brain; Dementia; Disease Models, Animal; Female; Glutathione; Interleukin-1beta; Male; Mecl

2020