Page last updated: 2024-10-30

mechlorethamine and Testicular Neoplasms

mechlorethamine has been researched along with Testicular Neoplasms in 17 studies

nitrogen mustard : Compounds having two beta-haloalkyl groups bound to a nitrogen atom, as in (X-CH2-CH2)2NR.

Testicular Neoplasms: Tumors or cancer of the TESTIS. Germ cell tumors (GERMINOMA) of the testis constitute 95% of all testicular neoplasms.

Research Excerpts

ExcerptRelevanceReference
"Relative risks (RRs) of stomach cancer and the radiation-related excess relative risk (ERR) per gray were calculated by conditional logistic regression analysis."1.35Roles of radiation dose and chemotherapy in the etiology of stomach cancer as a second malignancy. ( Aleman, BM; Besseling, G; de Bruin, ML; de Wit, R; Gietema, JA; Hauptmann, M; Kerst, JM; Noordijk, EM; Ribot, JG; van 't Veer, MB; van den Belt-Dusebout, AW; van Leeuwen, FE, 2009)
"We report about two cases of cancer of the testis occurring 2 and 7 years after Hodgkin's disease treated with combined chemotherapy and radiation therapy."1.28[Cancer of the testis after Hodgkin's disease. Apropos of 2 cases]. ( Averous, M; Chevallier, P; Grasset, D; Guiter, J; Iborra, F; Lavabre-Bertrand, T; Rebillard, X; Robert, M, 1992)
"Primary testicular neoplasms are not common childhood tumors, comprising about 1% of all childhood malignancies [1]."1.26Childhood embryonal carcinoma of testis, report of two unusual cases, and the implication on clinical management. ( Chu, JY; DeMello, D; McElfresh, AE; O'Connor, DM; Razek, AA, 1978)
"An occult testicular tumor must be sought, but primary mediastinal germinal tumors constitute a true entity."1.25Primary malignant germinal tumors of the mediastinum. A study of 24 cases. ( Cox, JD, 1975)

Research

Studies (17)

TimeframeStudies, this research(%)All Research%
pre-199013 (76.47)18.7374
1990's3 (17.65)18.2507
2000's1 (5.88)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
van den Belt-Dusebout, AW1
Aleman, BM1
Besseling, G1
de Bruin, ML1
Hauptmann, M1
van 't Veer, MB1
de Wit, R1
Ribot, JG1
Noordijk, EM1
Kerst, JM1
Gietema, JA1
van Leeuwen, FE1
ANKENMAN, GJ1
BALFOUR, J1
DUFOUR, A1
ANDRE, P1
COVILL, FJ1
HORNTRICH, J1
Cornbleet, MA1
Leonard, RC1
Smyth, JF1
Varterasian, ML1
Aref, A1
Karanes, C1
Chu, JY1
O'Connor, DM1
DeMello, D1
Razek, AA1
McElfresh, AE1
Cox, JD1
Robert, M1
Averous, M1
Lavabre-Bertrand, T1
Iborra, F1
Chevallier, P1
Rebillard, X1
Guiter, J1
Grasset, D1
Feuer, EJ1
Kessler, LG1
Baker, SG1
Triolo, HE1
Green, DT1
Frei, E1
Kithier, K1
Lusher, J1
Brought, J1
Poulik, MD1
Du Priest, RW1
Fletcher, WS1
Pommatau, E1
Brunat, M1
Mayer, H1
Dargent, M1
Astrakhan, VI1
Garin, AM1
Vvedenskaia, NA1
Bychkov, MB1
Jacobs, EM1
Johnson, FD1
Wood, DA1

Reviews

1 review available for mechlorethamine and Testicular Neoplasms

ArticleYear
High-dose alkylating agent therapy: a review of clinical experiences.
    Cancer drug delivery, 1984,Summer, Volume: 1, Issue:3

    Topics: Alkylating Agents; Busulfan; Carcinoma, Bronchogenic; Carmustine; Dose-Response Relationship, Drug;

1984

Other Studies

16 other studies available for mechlorethamine and Testicular Neoplasms

ArticleYear
Roles of radiation dose and chemotherapy in the etiology of stomach cancer as a second malignancy.
    International journal of radiation oncology, biology, physics, 2009, Dec-01, Volume: 75, Issue:5

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Case-Control Studies; Cohort Studies; Combine

2009
Nitrogen mustard in treatment of metastatic carcinoma of the testis.
    Canadian journal of surgery. Journal canadien de chirurgie, 1961, Volume: 4

    Topics: Choriocarcinoma; Dysgerminoma; Female; Humans; Male; Mechlorethamine; Nitrogen Mustard Compounds; Ov

1961
[APROPOS OF THE TREATMENT OF TUMORS OF THE TESTICLE].
    Journal d'urologie et de nephrologie, 1963, Volume: 69

    Topics: Castration; Choriocarcinoma; Dactinomycin; Female; Humans; Lung Neoplasms; Lymphatic Metastasis; Mal

1963
Teratoma of the testis treated with nitrogen mustard.
    Guy's Hospital reports, 1955, Volume: 104, Issue:1

    Topics: Humans; Male; Mechlorethamine; Neoplasms; Nitrogen Mustard Compounds; Teratoma; Testicular Neoplasms

1955
[Successful therapy of a metastasizing seminoma with nitrogen mustard N-oxide].
    Therapie der Gegenwart, 1960, Volume: 99

    Topics: Dysgerminoma; Female; Humans; Male; Mechlorethamine; Neoplasms; Neoplasms, Germ Cell and Embryonal;

1960
A blood stem cell transplant in a person with concomitant Hodgkin disease and testicular carcinoma.
    Bone marrow transplantation, 1997, Volume: 19, Issue:8

    Topics: Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Germinoma; Hematopoietic

1997
Childhood embryonal carcinoma of testis, report of two unusual cases, and the implication on clinical management.
    Medical and pediatric oncology, 1978, Volume: 4, Issue:2

    Topics: Castration; Child, Preschool; Chlorambucil; Cyclophosphamide; Dactinomycin; Doxorubicin; Humans; Inf

1978
Primary malignant germinal tumors of the mediastinum. A study of 24 cases.
    Cancer, 1975, Volume: 36, Issue:3

    Topics: Adolescent; Adult; Choriocarcinoma; Dysgerminoma; Humans; Male; Mechlorethamine; Mediastinum; Middle

1975
[Cancer of the testis after Hodgkin's disease. Apropos of 2 cases].
    Journal d'urologie, 1992, Volume: 98, Issue:3

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Dacarbazine; Doxorubicin; Dysgermi

1992
The impact of breakthrough clinical trials on survival in population based tumor registries.
    Journal of clinical epidemiology, 1991, Volume: 44, Issue:2

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cisplatin; Clinical Trials as Topic; Hodg

1991
Current status and new vistas in combination chemotherapy.
    The Mount Sinai journal of medicine, New York, 1985, Volume: 52, Issue:6

    Topics: Antineoplastic Combined Chemotherapy Protocols; Child; Combined Modality Therapy; Hodgkin Disease; H

1985
Effect of therapy on the serum level of alpha-1 fetoprotein in embryonal cell carcinoma.
    The Journal of pediatrics, 1972, Volume: 81, Issue:1

    Topics: Alpha-Globulins; Child, Preschool; Cyclophosphamide; Dactinomycin; Fetal Proteins; Humans; Immunodif

1972
Chemotherapy of testicular germinal tumors.
    Oncology, 1973, Volume: 28, Issue:2

    Topics: Alkylating Agents; Antineoplastic Agents; Chlorambucil; Cyclophosphamide; Dactinomycin; Dysgerminoma

1973
Complete regression of metastatic tumors of the adult with antimitotic treatment.
    Journal of surgical oncology, 1974, Volume: 6, Issue:1

    Topics: Adolescent; Adult; Antineoplastic Agents; Choriocarcinoma; Cyclophosphamide; Dactinomycin; Female; F

1974
[Chemotherapy in the terminal stages of tumors].
    Voprosy onkologii, 1968, Volume: 14, Issue:6

    Topics: Alkylating Agents; Bone Neoplasms; Cyclophosphamide; Dysgerminoma; Lymphatic Metastasis; Lymphoma, L

1968
Stage 3 metastatic malignant testicular tumors. Treatment with intermittent and combined chemotherapy.
    Cancer, 1966, Volume: 19, Issue:11

    Topics: Adult; Dactinomycin; Dysgerminoma; Humans; Idoxuridine; Lung Neoplasms; Male; Mechlorethamine; Metho

1966