Page last updated: 2024-10-30

mechlorethamine and Skin Ulcer

mechlorethamine has been researched along with Skin Ulcer in 5 studies

nitrogen mustard : Compounds having two beta-haloalkyl groups bound to a nitrogen atom, as in (X-CH2-CH2)2NR.

Skin Ulcer: An ULCER of the skin and underlying tissues.

Research Excerpts

Excerpt	Relevance	Reference
" Thiosulfate dosing studies showed that a molar excess of at least 200:1 (Na2S2O3:HN2) was required for significant antidotal activity."	1.27	Efficacy of sodium thiosulfate as a local antidote to mechlorethamine skin toxicity in the mouse. ( Alberts, DS; Dorr, RT; Soble, M, 1988)

5 other studies available for mechlorethamine and Skin Ulcer

Article	Year
PAINTING TREATMENT OF NITROGEN MUSTARD IN MYCOSIS FUNGOIDES. Dermatologica, 1965, Volume: 130 Topics: Drug Therapy; Erythema; Fever; Geriatrics; Humans; Hypersensitivity; Hypersensitivity, Delayed; Hype	1965
The healing of resistant skin ulcers after treatment with nitrogen mustard; a preliminary note. The American journal of the medical sciences, 1948, Volume: 216, Issue:3 Topics: Humans; Mechlorethamine; Mustard Plant; Nitrogen; Skin Ulcer; Ulcer; Wound Healing	1948
Histiocytosis X with unusual facial and axillary ulceration responding to topical nitrogen mustard. Journal of the Royal Society of Medicine, 1982, Volume: 75, Issue:4 Topics: Adult; Axilla; Facial Dermatoses; Histiocytosis, Langerhans-Cell; Humans; Male; Mechlorethamine; Ski	1982
[Lymphomatoid granulomatosis]. Annales de dermatologie et de venereologie, 1982, Volume: 109, Issue:9 Topics: Humans; Lymphomatoid Granulomatosis; Male; Mechlorethamine; Middle Aged; Skin Diseases; Skin Ulcer	1982
Efficacy of sodium thiosulfate as a local antidote to mechlorethamine skin toxicity in the mouse. Cancer chemotherapy and pharmacology, 1988, Volume: 22, Issue:4 Topics: Animals; Dose-Response Relationship, Drug; Female; Mechlorethamine; Mice; Mice, Inbred BALB C; Skin;	1988