mechlorethamine has been researched along with Skin Diseases in 40 studies
nitrogen mustard : Compounds having two beta-haloalkyl groups bound to a nitrogen atom, as in (X-CH2-CH2)2NR.
Skin Diseases: Diseases involving the DERMIS or EPIDERMIS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Ten patients with advanced stage (TNM IIB-IVB) mycosis fungoides were treated with a combination chemotherapy program consisting of bleomycin and methotrexate weekly, doxorubicin every 3 weeks, and topical nitrogen mustard daily (BAM-M)." | 7.67 | Treatment of advanced stage mycosis fungoides with bleomycin, doxorubicin, and methotrexate with topical nitrogen mustard (BAM-M). ( Adelstein, DJ; Davis, BR; Hines, JD; Zakem, MH, 1986) |
| "Ten patients with advanced stage (TNM IIB-IVB) mycosis fungoides were treated with a combination chemotherapy program consisting of bleomycin and methotrexate weekly, doxorubicin every 3 weeks, and topical nitrogen mustard daily (BAM-M)." | 3.67 | Treatment of advanced stage mycosis fungoides with bleomycin, doxorubicin, and methotrexate with topical nitrogen mustard (BAM-M). ( Adelstein, DJ; Davis, BR; Hines, JD; Zakem, MH, 1986) |
| "Cutaneous manifestations of Hodgkin's disease are relatively uncommon." | 2.38 | Hodgkin's disease presenting in the skin: case report and review of the literature. ( Hayes, TG; Rabin, VR; Rosen, T; Zubler, MA, 1990) |
| " Adverse events (AE) were recorded in 43." | 1.72 | Chlormethine Gel is Efficient and Safe in Mycosis Fungoides Skin Lesions. ( Dalamaga, M; Koumourtzis, M; Lampadaki, K; Papadavid, E, 2022) |
| "Skin lesions in Langerhans cell histiocytosis (LCH) are often painful and difficult to treat." | 1.31 | Long term follow up of topical mustine treatment for cutaneous langerhans cell histiocytosis. ( Atherton, DA; Harper, JI; Hoeger, PH; Nanduri, VR; Pritchard, J, 2000) |
| "However, presently there is no specific treatment for chemical burns of partial thickness." | 1.30 | Early nonsurgical removal of chemically injured tissue enhances wound healing in partial thickness burns. ( Ben-Bassat, H; Breiterman, S; Chaouat, M; Eldad, A; Palanker, D; Weinberg, A, 1998) |
| "Clinical course or treatment for granulomatous fungoides mycosis or classical fungoid mycosis." | 1.30 | [Granulomatous mycosis fungoides histologically simulating cutaneous sarcoidosis]. ( Croué, A; François, S; Maillard, H; Verret, JL, 1998) |
| "In 16 children with multisystem Langerhans cell histiocytosis (mean age 22 months, range 5 to 36 months) severe symptomatic skin involvement was treated with topical nitrogen mustard (mechlorethamine hydrochloride)." | 1.28 | Topical nitrogen mustard: an effective treatment for cutaneous Langerhans cell histiocytosis. ( Atherton, DJ; Broadbent, V; Pritchard, J; Sheehan, MP, 1991) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 21 (52.50) | 18.7374 |
| 1990's | 9 (22.50) | 18.2507 |
| 2000's | 3 (7.50) | 29.6817 |
| 2010's | 4 (10.00) | 24.3611 |
| 2020's | 3 (7.50) | 2.80 |
| Authors | Studies |
|---|---|
| Koumourtzis, M | 2 |
| Lampadaki, K | 2 |
| Dalamaga, M | 2 |
| Papadavid, E | 2 |
| Nikolaou, V | 1 |
| Marinos, L | 1 |
| Patsatsi, A | 1 |
| Georgiou, E | 1 |
| Stratigos, A | 1 |
| Bui, AN | 1 |
| Puleo, AE | 1 |
| Canales, AL | 1 |
| Jacobsen, ED | 1 |
| LeBoeuf, NR | 1 |
| Schlinsog, AS | 1 |
| Kreft, B | 1 |
| Marsch, WC | 1 |
| Tewari-Singh, N | 1 |
| Jain, AK | 1 |
| Inturi, S | 1 |
| White, CW | 1 |
| Agarwal, R | 1 |
| OSBORNE, ED | 1 |
| JORDON, JW | 1 |
| Sharma, M | 1 |
| Pant, SC | 1 |
| Pant, JC | 1 |
| Vijayaraghavan, R | 1 |
| Lindahl, LM | 1 |
| Fenger-Grøn, M | 1 |
| Iversen, L | 1 |
| VILANOVA, X | 2 |
| PINOL, J | 2 |
| FOLBERTH, S | 1 |
| MAZZINI, MA | 1 |
| MOM, AM | 1 |
| GARCIA, S | 1 |
| JAKSO, G | 2 |
| SIPOS, K | 2 |
| THIERS, H | 1 |
| COLOMB, D | 1 |
| FAYOLLE, J | 1 |
| ARCADIO, F | 1 |
| LIBANSKY, J | 1 |
| TRAPL, J | 1 |
| LEDER, M | 1 |
| Kenar, L | 1 |
| Karayilanoğlu, T | 1 |
| Yuksel, A | 1 |
| Gunhan, O | 1 |
| Kose, S | 1 |
| Kurt, B | 1 |
| Thivolet, J | 1 |
| Cambazard, F | 1 |
| Euvrard, S | 1 |
| Hermier, M | 1 |
| Kanitakis, J | 1 |
| Nethercott, JR | 1 |
| Murray, AH | 1 |
| Medwidsky, W | 1 |
| Chalvardjian, A | 1 |
| Lemarchand-Venencie, F | 1 |
| Saurat, JH | 1 |
| Brandt, F | 1 |
| Lipman, M | 1 |
| Taylor, JR | 1 |
| Halprin, KM | 1 |
| Wallach, D | 1 |
| Mayaud, C | 1 |
| Palangié, A | 1 |
| Cottenot, F | 1 |
| Forssman, T | 1 |
| Fluhr, J | 1 |
| Djawari, D | 1 |
| Gloor, M | 1 |
| Rumpelt, HJ | 1 |
| Wormser, U | 2 |
| Brodsky, B | 2 |
| Green, BS | 1 |
| Arad-Yellin, R | 1 |
| Nyska, A | 1 |
| Smith, KJ | 1 |
| Smith, WJ | 1 |
| Hamilton, T | 1 |
| Skelton, HG | 1 |
| Graham, JS | 1 |
| Okerberg, C | 1 |
| Moeller, R | 1 |
| Hackley, BE | 1 |
| Eldad, A | 1 |
| Weinberg, A | 1 |
| Breiterman, S | 1 |
| Chaouat, M | 1 |
| Palanker, D | 1 |
| Ben-Bassat, H | 1 |
| Maillard, H | 1 |
| Croué, A | 1 |
| François, S | 1 |
| Verret, JL | 1 |
| Hoeger, PH | 1 |
| Nanduri, VR | 1 |
| Harper, JI | 1 |
| Atherton, DA | 1 |
| Pritchard, J | 2 |
| Reich, R | 1 |
| Pascher, F | 1 |
| Zachariae, C | 1 |
| Larsen, CS | 1 |
| Kaltoft, K | 1 |
| Deleuran, B | 1 |
| Larsen, CG | 1 |
| Thestrup-Pedersen, K | 1 |
| Smith, SP | 1 |
| Konnikov, N | 1 |
| Sheehan, MP | 1 |
| Atherton, DJ | 1 |
| Broadbent, V | 1 |
| Hayes, TG | 1 |
| Rabin, VR | 1 |
| Rosen, T | 1 |
| Zubler, MA | 1 |
| Zakem, MH | 1 |
| Davis, BR | 1 |
| Adelstein, DJ | 1 |
| Hines, JD | 1 |
| Weigand, DA | 1 |
| Schubert, B | 1 |
| Bazex, J | 1 |
| Baumgartner, G | 1 |
| Duschet, P | 1 |
| Schwarz, T | 1 |
| Partsch, H | 1 |
| Gschnait, F | 1 |
| Stacher, A | 1 |
| Kind, LS | 1 |
| Petersen, WA | 1 |
1 review available for mechlorethamine and Skin Diseases
| Article | Year |
|---|---|
Hodgkin's disease presenting in the skin: case report and review of the literature.
Topics: Antineoplastic Combined Chemotherapy Protocols; Eczema; Hodgkin Disease; Humans; Male; Mechlorethami | 1990 |
1 trial available for mechlorethamine and Skin Diseases
| Article | Year |
|---|---|
Chlormethine gel is effective for the treatment of skin lesions in patients with early- and late-stage mycosis fungoides in clinical practice.
Topics: Combined Modality Therapy; Humans; Mechlorethamine; Mycosis Fungoides; Skin Diseases; Skin Neoplasms | 2022 |
38 other studies available for mechlorethamine and Skin Diseases
| Article | Year |
|---|---|
Chlormethine Gel is Efficient and Safe in Mycosis Fungoides Skin Lesions.
Topics: Antineoplastic Agents; Antineoplastic Agents, Alkylating; Humans; Mechlorethamine; Mycosis Fungoides | 2022 |
Cutaneous Langerhans Cell Histiocytosis Responsive to Topical Nitrogen Mustard.
Topics: Administration, Cutaneous; Aged; Aged, 80 and over; Alkylating Agents; Biopsy; Female; Histiocytosis | 2020 |
Cutaneous Langerhans cell histiocytosis - an indication for dermatological pharmacotherapy with topical nitrogen mustard.
Topics: Administration, Cutaneous; Adolescent; Dermatologic Agents; Hand Dermatoses; Histiocytosis, Langerha | 2018 |
Clinically-relevant cutaneous lesions by nitrogen mustard: useful biomarkers of vesicants skin injury in SKH-1 hairless and C57BL/6 mice.
Topics: Animals; Biomarkers; Disease Progression; Edema; Erythema; Irritants; Mechlorethamine; Mice; Mice, H | 2013 |
Nitrogen mustard therapy in cutaneous blastomatous disease.
Topics: Administration, Cutaneous; Humans; Mechlorethamine; Skin Diseases | 1947 |
Nitrogen and sulphur mustard induced histopathological observations in mouse visceral organs.
Topics: Animals; Chemical and Drug Induced Liver Injury; Chemical Warfare Agents; Female; Kidney Diseases; M | 2010 |
Topical nitrogen mustard therapy in patients with Langerhans cell histiocytosis.
Topics: Administration, Cutaneous; Adolescent; Adult; Child; Child, Preschool; Dermatitis, Irritant; Dermato | 2012 |
[Treatment of psoriasis, poikilodermatomyositis and erythroderma with nitrogen mustards].
Topics: Dermatitis, Exfoliative; Dermatomyositis; Humans; Mechlorethamine; Nitrogen Mustard Compounds; Pigme | 1952 |
[Bacon as therapeutic substance in pediatrics].
Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Child; Doxorubicin; Humans; Infant; Infan | 1953 |
[Nitrogen mustards in dermatology].
Topics: Dermatology; Mechlorethamine; Nitrogen Mustard Compounds; Skin Diseases | 1954 |
[Local administration of nitrogen mustard in some skin diseases].
Topics: Mechlorethamine; Nitrogen Mustard Compounds; Skin Diseases | 1956 |
[Local administration of nitrogen mustard in some skin diseases].
Topics: Mechlorethamine; Nitrogen Mustard Compounds; Skin Diseases | 1956 |
[Local administration of nitrogen mustard in some skin diseases].
Topics: Mechlorethamine; Nitrogen Mustard Compounds; Skin Diseases | 1956 |
[Local administration of nitrogen mustard in some skin diseases].
Topics: Mechlorethamine; Nitrogen Mustard Compounds; Skin Diseases | 1956 |
[Profuse lymphodermia; cure by combined cortisone & chloraminophen].
Topics: Chlorambucil; Cortisone; Disease; Lymph Nodes; Lymphatic Diseases; Mechlorethamine; Nitrogen Mustard | 1959 |
Chlorambucil in erythrodermia.
Topics: Chlorambucil; Dermatitis, Exfoliative; Humans; Mechlorethamine; Nitrogen Mustard Compounds; Skin Dis | 1960 |
[Nitrogen mustards in dermatology].
Topics: Dermatology; Mechlorethamine; Nitrogen Mustard Compounds; Skin Diseases | 1951 |
[Treatment of psoriasis, poikilodermatomyositis and erythrodermia with nitrogen mustards].
Topics: Mechlorethamine; Nitrogen Mustard Compounds; Pigmentation Disorders; Psoriasis; Skin Diseases | 1952 |
[Occupational skin diseases caused by nitrogen mustard].
Topics: Dermatitis; Dermatitis, Contact; Mechlorethamine; Nitrogen Mustard Compounds; Skin; Skin Diseases | 1952 |
Evaluation of protective ointments used against dermal effects of nitrogen mustard, a vesicant warfare agent.
Topics: alpha-Tocopherol; Animals; Chemical Warfare Agents; Chemoprevention; Chlorides; Dimethylpolysiloxane | 2005 |
[Isolated cutaneous Langerhans histiocytosis. Clinical and immunohistologic improvement after local application of nitrogen mustard].
Topics: Administration, Topical; Fluorescent Antibody Technique; Histiocytosis, Langerhans-Cell; Humans; Inf | 1984 |
Histiocytosis X in two adults. Treatment with topical mechlorethamine.
Topics: Administration, Topical; Adult; Aged; Female; Histiocytosis, Langerhans-Cell; Humans; Ilium; Male; M | 1983 |
[Topical therapy using nitrogen mustard (chlormethine hydrochlorate) for cutaneous manifestations of histiocytosis X (author's transl)].
Topics: Administration, Topical; Female; Histiocytosis, Langerhans-Cell; Humans; Infant; Male; Mechlorethami | 1982 |
Topical nitrogen mustard therapy in multicentric reticulohistiocytosis.
Topics: Administration, Topical; Arthritis; Humans; Male; Mechlorethamine; Middle Aged; Skin Diseases | 1982 |
[Lymphomatoid granulomatosis].
Topics: Humans; Lymphomatoid Granulomatosis; Male; Mechlorethamine; Middle Aged; Skin Diseases; Skin Ulcer | 1982 |
[Treatment of Langerhans-cell histiocytosis by oral cyclosporin A and topical nitrogen mustard].
Topics: Administration, Oral; Administration, Topical; Cyclosporine; Histiocytosis, Langerhans-Cell; Humans; | 1994 |
Protective effect of povidone-iodine ointment against skin lesions induced by sulphur and nitrogen mustards and by non-mustard vesicants.
Topics: Animals; Anti-Infective Agents, Local; Chemical Warfare Agents; Guinea Pigs; Irritants; Magnetic Res | 1997 |
Histopathologic and immunohistochemical features in human skin after exposure to nitrogen and sulfur mustard.
Topics: Autoantigens; Biomarkers; Carrier Proteins; Cell Adhesion Molecules; Collagen; Collagen Type XVII; C | 1998 |
Early nonsurgical removal of chemically injured tissue enhances wound healing in partial thickness burns.
Topics: Administration, Topical; Animals; Anti-Infective Agents, Local; Antineoplastic Agents, Alkylating; B | 1998 |
[Granulomatous mycosis fungoides histologically simulating cutaneous sarcoidosis].
Topics: Adult; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Diagnosis, | 1998 |
Long term follow up of topical mustine treatment for cutaneous langerhans cell histiocytosis.
Topics: Administration, Topical; Alkylating Agents; Child; Child, Preschool; Dermatologic Agents; Female; Fo | 2000 |
Topical treatment with povidone iodine reduces nitrogen mustard-induced skin collagenolytic activity.
Topics: Administration, Topical; Animals; Dermatologic Agents; Disease Models, Animal; Guinea Pigs; Irritant | 2002 |
Systemic reactions to topically applied drugs.
Topics: Administration, Topical; Adrenal Cortex Hormones; Adult; Aged; Boric Acids; Child; Child, Preschool; | 1978 |
Soluble IL2 receptor serum levels and epidermal cytokines in mycosis fungoides and related disorders.
Topics: Aged; Aged, 80 and over; Chemotaxis; Cytokines; Female; Humans; Male; Mechlorethamine; Middle Aged; | 1991 |
Eruptive epidermal cysts and multiple squamous cell carcinomas after therapy for cutaneous T-cell lymphoma.
Topics: Administration, Cutaneous; Carcinoma, Squamous Cell; Epidermal Cyst; Humans; Lymphoma, T-Cell, Cutan | 1991 |
Topical nitrogen mustard: an effective treatment for cutaneous Langerhans cell histiocytosis.
Topics: Administration, Topical; Child, Preschool; Drug Evaluation; Female; Histiocytosis, Langerhans-Cell; | 1991 |
Treatment of advanced stage mycosis fungoides with bleomycin, doxorubicin, and methotrexate with topical nitrogen mustard (BAM-M).
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Chemical and Drug Induced Li | 1986 |
Chemical warfare.
Topics: Chemical Warfare Agents; Humans; Mechlorethamine; Mustard Compounds; Mustard Gas; Skin Diseases | 1989 |
[Photochemotherapy of eyelid lesions].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Eyelid Diseases; Female; Hodgkin Disease; Huma | 1987 |
Lymphomatoid papulosis: remission following intravenously administered acyclovir.
Topics: Acyclovir; Antineoplastic Combined Chemotherapy Protocols; Hodgkin Disease; Humans; Injections, Intr | 1986 |
Concanavalin A in vivo: induction of hemorrhagic skin lesions (Arthus-like reactions) in mice.
Topics: Alpha-Globulins; Animals; Arabinose; Arthus Reaction; Chemical Precipitation; Glycosides; Hemorrhage | 1968 |