mechlorethamine has been researched along with Retinoblastoma in 7 studies
nitrogen mustard : Compounds having two beta-haloalkyl groups bound to a nitrogen atom, as in (X-CH2-CH2)2NR.
Retinoblastoma: A malignant tumor arising from the nuclear layer of the retina that is the most common primary tumor of the eye in children. The tumor tends to occur in early childhood or infancy and may be present at birth. The majority are sporadic, but the condition may be transmitted as an autosomal dominant trait. Histologic features include dense cellularity, small round polygonal cells, and areas of calcification and necrosis. An abnormal pupil reflex (leukokoria); NYSTAGMUS, PATHOLOGIC; STRABISMUS; and visual loss represent common clinical characteristics of this condition. (From DeVita et al., Cancer: Principles and Practice of Oncology, 5th ed, p2104)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| KUPFER, C | 2 |
| PALOMINO DENA, F | 1 |
| Sevel, D | 1 |
| Sealy, R | 1 |
| Lawton, E | 1 |
| Lawhorn, TI | 1 |
| Stone, HH | 1 |
| Martin, JD | 1 |
| Mahaley, MS | 1 |
| Woodhall, B | 1 |
| Finklestein, JZ | 1 |
| Ekert, H | 1 |
| Isaacs, H | 1 |
| Higgins, G | 1 |
1 review available for mechlorethamine and Retinoblastoma
| Article | Year |
|---|---|
Chemotherapy in solid tumors of childhood.
Topics: Abdominal Neoplasms; Adolescent; Child; Child, Preschool; Cyclophosphamide; Dactinomycin; Eye Neopla | 1972 |
1 trial available for mechlorethamine and Retinoblastoma
| Article | Year |
|---|---|
Cooperative clinical trials. The Second Ticho Memorial Lecture.
Topics: Aged; Clinical Trials as Topic; Diabetic Retinopathy; Eye Diseases; Eye Neoplasms; Fluorescein Angio | 1975 |
5 other studies available for mechlorethamine and Retinoblastoma
| Article | Year |
|---|---|
Retinoblastoma treated with intravenous nitrogen mustard.
Topics: Mechlorethamine; Neuroectodermal Tumors, Primitive, Peripheral; Nitrogen Mustard Compounds; Retinobl | 1953 |
[Treatment of retinoblastoma in the first stage (endocular). Preliminary communication].
Topics: Communication; Mechlorethamine; Neoplasms; Neuroectodermal Tumors, Primitive, Peripheral; Nitrogen M | 1960 |
Retinoblastoma at Groote Schuur Hospital 1952-1972.
Topics: Cell Survival; Cells, Cultured; Child, Preschool; Cobalt Radioisotopes; Cyclophosphamide; Dactinomyc | 1973 |
Regional chemotherapeutic perfusion and infusion of brain and face tumors.
Topics: Adenocarcinoma; Ameloblastoma; Antineoplastic Agents; Astrocytoma; Brain Neoplasms; Carcinoma; Carci | 1967 |
Bone marrow metastases in children with solid tumors.
Topics: Bone Marrow Diseases; Bone Marrow Examination; Bone Neoplasms; Child; Cyclophosphamide; Dactinomycin | 1970 |