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mechlorethamine and Pulmonary Edema

mechlorethamine has been researched along with Pulmonary Edema in 9 studies

nitrogen mustard : Compounds having two beta-haloalkyl groups bound to a nitrogen atom, as in (X-CH2-CH2)2NR.

Pulmonary Edema: Excessive accumulation of extravascular fluid in the lung, an indication of a serious underlying disease or disorder. Pulmonary edema prevents efficient PULMONARY GAS EXCHANGE in the PULMONARY ALVEOLI, and can be life-threatening.

Research Excerpts

ExcerptRelevanceReference
"All rabbits died of respiratory failure with pulmonary edema, and although chemotherapy decreased the number of neutrophils in the lungs by greater than 90%, it did not influence survival time or extravascular lung water content."1.27Oxygen-induced lung microvascular injury in neutropenic rabbits and lambs. ( Bland, RD; Hazinski, TA; Raj, JU, 1985)
"Acute edematous lung injury is associated with a marked increase in the number of granulocytes in the alveoli and microvasculature of the lung."1.26Granulocytes mediate acute edematous lung injury in rabbits and in isolated rabbit lungs perfused with phorbol myristate acetate: role of oxygen radicals. ( McMurtry, I; Repine, JE; Shasby, DM; Shasby, SS; Tate, RM; Vanbenthuysen, KM, 1982)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19908 (88.89)18.7374
1990's1 (11.11)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
CUTRONA, E1
CATANIA, E2
Raj, JU2
Bland, RD3
Shasby, DM2
Vanbenthuysen, KM1
Tate, RM1
Shasby, SS1
McMurtry, I1
Repine, JE2
Fox, RB1
Harada, RN1
Carlton, DP1
Albertine, KH1
Cho, SC1
Lont, M1
Basadre, JO1
Sugi, K1
Traber, DL1
Traber, LD1
Niehaus, GD1
Herndon, DN1
Winn, R1
Maunder, R1
Chi, E1
Harlan, J1
Hazinski, TA1

Other Studies

9 other studies available for mechlorethamine and Pulmonary Edema

ArticleYear
[Oxidation-reduction processes, acute adrenaline-induced pulmonary edema and nitrogen mustard].
    Rivista di patologia e clinica, 1960, Volume: 15

    Topics: Epinephrine; Mechlorethamine; Nitrogen Mustard Compounds; Oxidation-Reduction; Pulmonary Edema

1960
[Experimental studies on the effect of nitrogen mustard in acute pulmonary edema produced by adrenalin].
    Rivista di patologia e clinica, 1959, Volume: 14

    Topics: Epinephrine; Mechlorethamine; Nitrogen Mustard Compounds; Pulmonary Edema

1959
Neutrophil depletion does not prevent oxygen-induced lung injury in rabbits.
    Chest, 1983, Volume: 83, Issue:5 Suppl

    Topics: Agranulocytosis; Animals; Hemodynamics; Mechlorethamine; Neutropenia; Oxygen; Pulmonary Edema; Rabbi

1983
Granulocytes mediate acute edematous lung injury in rabbits and in isolated rabbit lungs perfused with phorbol myristate acetate: role of oxygen radicals.
    The American review of respiratory disease, 1982, Volume: 125, Issue:4

    Topics: Agranulocytosis; Animals; Free Radicals; Granulocytes; Granulomatous Disease, Chronic; Lung; Lung In

1982
Reduction of the edema of acute hyperoxic lung injury by granulocyte depletion.
    Journal of applied physiology: respiratory, environmental and exercise physiology, 1982, Volume: 52, Issue:5

    Topics: Animals; Granulocytes; Hyperbaric Oxygenation; Leukocyte Count; Lung; Mechlorethamine; Oxygen; Preme

1982
Role of neutrophils in lung vascular injury and edema after premature birth in lambs.
    Journal of applied physiology (Bethesda, Md. : 1985), 1997, Volume: 83, Issue:4

    Topics: Alkylating Agents; Animals; Animals, Newborn; Blood Gas Analysis; Extravascular Lung Water; Female;

1997
The effect of leukocyte depletion on smoke inhalation injury in sheep.
    Surgery, 1988, Volume: 104, Issue:2

    Topics: Animals; Burns, Inhalation; Capillary Permeability; Hemodynamics; Leukopenia; Lymph; Mechlorethamine

1988
Neutrophil depletion does not prevent lung edema after endotoxin infusion in goats.
    Journal of applied physiology (Bethesda, Md. : 1985), 1987, Volume: 62, Issue:1

    Topics: 6-Ketoprostaglandin F1 alpha; Animals; Blood Pressure; Blood Proteins; Body Water; Cardiac Output; E

1987
Oxygen-induced lung microvascular injury in neutropenic rabbits and lambs.
    Journal of applied physiology (Bethesda, Md. : 1985), 1985, Volume: 58, Issue:3

    Topics: Agranulocytosis; Animals; Blood Pressure; Capillary Permeability; Cardiac Output; Hydroxyurea; Lung;

1985