Page last updated: 2024-10-30

mechlorethamine and Prostatic Neoplasms

mechlorethamine has been researched along with Prostatic Neoplasms in 11 studies

nitrogen mustard : Compounds having two beta-haloalkyl groups bound to a nitrogen atom, as in (X-CH2-CH2)2NR.

Prostatic Neoplasms: Tumors or cancer of the PROSTATE.

Research Excerpts

ExcerptRelevanceReference
"Estramustine (EM) is a conjugate of estradiol and nor-nitrogen mustard (nor-HN2), which is effective in the treatment of prostate cancer."5.27Antiinvasive activity of estramustine on malignant MO4 mouse cells and on DU-145 human prostate carcinoma cells in vitro. ( De Bruyne, GK; Dragonetti, CH; Hartley-Asp, B; Mareel, MM; Rabaey, ML; Segers, JL; Storme, GA, 1988)
"Estracyt is a new drug for treatment of prostatic cancer, which is a molecule combining estradiol and nornitrogen mustard by a carbamate link."1.27[Pharmacology and metabolism of a new therapeutic drug for prostatic cancer "Estracyt"]. ( Shida, K; Yamanaka, H, 1984)
"Estramustine (EM) is a conjugate of estradiol and nor-nitrogen mustard (nor-HN2), which is effective in the treatment of prostate cancer."1.27Antiinvasive activity of estramustine on malignant MO4 mouse cells and on DU-145 human prostate carcinoma cells in vitro. ( De Bruyne, GK; Dragonetti, CH; Hartley-Asp, B; Mareel, MM; Rabaey, ML; Segers, JL; Storme, GA, 1988)

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19908 (72.73)18.7374
1990's0 (0.00)18.2507
2000's2 (18.18)29.6817
2010's1 (9.09)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Jones, GB1
Mitchell, MO1
Weinberg, JS1
D'Amico, AV1
Bubley, GJ1
Yu, Z1
Zhao, J1
Hua, Z1
Wang, X3
Wang, H1
Yu, JX1
DUNNING, WF2
CURTIS, MR1
Zhang, X1
Ling, MT1
Wong, YC1
Goodwin, WE1
Mims, MM1
Young, HH1
Yamanaka, H1
Shida, K1
Sander, S1
Mareel, MM1
Storme, GA1
Dragonetti, CH1
De Bruyne, GK1
Hartley-Asp, B1
Segers, JL1
Rabaey, ML1
Yagoda, A1
Pommatau, E1
Brunat, M1
Mayer, H1
Dargent, M1

Reviews

1 review available for mechlorethamine and Prostatic Neoplasms

ArticleYear
Proceedings: Non-hormonal cytotoxic agents in the treatment of prostatic adenocarcinoma.
    Cancer, 1973, Volume: 32, Issue:5

    Topics: Acid Phosphatase; Adenocarcinoma; Aniline Compounds; Bone Neoplasms; Cyclophosphamide; Evaluation St

1973

Other Studies

10 other studies available for mechlorethamine and Prostatic Neoplasms

ArticleYear
Towards enzyme activated antiprostatic agents.
    Bioorganic & medicinal chemistry letters, 2000, Sep-04, Volume: 10, Issue:17

    Topics: Antineoplastic Agents; Humans; Male; Prodrugs; Prostate-Specific Antigen; Prostatic Neoplasms

2000
Novel
    Chemical biology & drug design, 2017, Volume: 90, Issue:5

    Topics: beta-Galactosidase; Breast Neoplasms; Cell Line, Tumor; Enzyme Assays; Female; Halogenation; Humans;

2017
PROSTATE CANCER IN THE RAT.
    National Cancer Institute monograph, 1963, Volume: 12

    Topics: Androgens; Estradiol Congeners; Estrogens; Estrone; Humans; Male; Mechlorethamine; Neoplasms; Neopla

1963
COMPARATIVE RESPONSE OF A SPECTRUM OF TRANSPLANTABLE RAT NEOPLASMS TO NITROGEN MUSTARD, TRIETHYLENEMELAMINE, AND A GROUP OF BENZALDEHYDE MUSTARD DERIVATIVES.
    Cancer chemotherapy reports, 1964, Volume: 36

    Topics: Animals; Benzaldehydes; Carcinoma, Bronchogenic; Carcinoma, Hepatocellular; Female; Humans; Injectio

1964
Evidence of a novel antiapoptotic factor: role of inhibitor of differentiation or DNA binding (Id-1) in anticancer drug-induced apoptosis.
    Cancer science, 2007, Volume: 98, Issue:3

    Topics: Antineoplastic Agents; Apoptosis; Breast Neoplasms; Carcinoma, Hepatocellular; Catechin; Cell Line,

2007
Rhabdomyosarcoma of the prostate in a child; first 5-year survival. (Combined treatment by preoperative, local irradiation; actinomycin D; intra-arterial nitrogen mustard and hypothermia; radical surgery and ureterosigmoidostomy).
    Transactions of the American Association of Genito-Urinary Surgeons, 1967, Volume: 59

    Topics: Child, Preschool; Dactinomycin; Humans; Hypothermia, Induced; Injections, Intra-Arterial; Male; Mech

1967
[Pharmacology and metabolism of a new therapeutic drug for prostatic cancer "Estracyt"].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1984, Volume: 11, Issue:3

    Topics: Animals; Antineoplastic Agents; Estramustine; Estrone; Follicle Stimulating Hormone; Humans; Luteini

1984
[Estracyt treatment in prostatic neoplasms].
    Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 1976, Jan-10, Volume: 96, Issue:1

    Topics: Administration, Oral; Aged; Drug Evaluation; Estradiol; Estramustine; Humans; Injections, Intravenou

1976
Antiinvasive activity of estramustine on malignant MO4 mouse cells and on DU-145 human prostate carcinoma cells in vitro.
    Cancer research, 1988, Apr-01, Volume: 48, Issue:7

    Topics: Animals; Carcinoma; Cell Movement; Estradiol; Estramustine; Humans; Male; Mechlorethamine; Mice; Mic

1988
Complete regression of metastatic tumors of the adult with antimitotic treatment.
    Journal of surgical oncology, 1974, Volume: 6, Issue:1

    Topics: Adolescent; Adult; Antineoplastic Agents; Choriocarcinoma; Cyclophosphamide; Dactinomycin; Female; F

1974