mechlorethamine has been researched along with Primary Ovarian Insufficiency in 4 studies
nitrogen mustard : Compounds having two beta-haloalkyl groups bound to a nitrogen atom, as in (X-CH2-CH2)2NR.
Primary Ovarian Insufficiency: Cessation of ovarian function after MENARCHE but before the age of 40, without or with OVARIAN FOLLICLE depletion. It is characterized by the presence of OLIGOMENORRHEA or AMENORRHEA, elevated GONADOTROPINS, and low ESTRADIOL levels. It is a state of female HYPERGONADOTROPIC HYPOGONADISM. Etiologies include genetic defects, autoimmune processes, chemotherapy, radiation, and infections. The most commonly known genetic cause is the expansion of a CGG repeat to 55 to 199 copies in the 5' untranslated region in the X-linked FMR1 gene.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (25.00) | 18.2507 |
| 2000's | 3 (75.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Tempone, A | 1 |
| Giuseppe, L | 1 |
| Attilio, G | 1 |
| Edoardo, DN | 1 |
| Loredana, G | 1 |
| Cristina, L | 1 |
| Vincenzo, L | 1 |
| van Beek, RD | 1 |
| van den Heuvel-Eibrink, MM | 1 |
| Laven, JS | 1 |
| de Jong, FH | 1 |
| Themmen, AP | 1 |
| Hakvoort-Cammel, FG | 1 |
| van den Bos, C | 1 |
| van den Berg, H | 1 |
| Pieters, R | 1 |
| de Muinck Keizer-Schrama, SM | 1 |
| Clark, ST | 1 |
| Radford, JA | 1 |
| Crowther, D | 1 |
| Swindell, R | 1 |
| Shalet, SM | 1 |
2 trials available for mechlorethamine and Primary Ovarian Insufficiency
| Article | Year |
|---|---|
Ovarian function after cancer treatment in young women affected by Hodgkin disease (HD).
Topics: Adolescent; Adult; Amenorrhea; Anti-Mullerian Hormone; Antineoplastic Combined Chemotherapy Protocol | 2007 |
Gonadal function following chemotherapy for Hodgkin's disease: a comparative study of MVPP and a seven-drug hybrid regimen.
Topics: Adolescent; Adult; Amenorrhea; Antineoplastic Combined Chemotherapy Protocols; Chlorambucil; Doxorub | 1995 |
2 other studies available for mechlorethamine and Primary Ovarian Insufficiency
| Article | Year |
|---|---|
Ovarian function preservation in patients under chemotherapy treatment.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Cryopreservation; Cyclophosphamide; Female; F | 2008 |
Anti-Mullerian hormone is a sensitive serum marker for gonadal function in women treated for Hodgkin's lymphoma during childhood.
Topics: Adolescent; Adult; Age Factors; Age of Onset; Anti-Mullerian Hormone; Antineoplastic Combined Chemot | 2007 |