mechlorethamine has been researched along with Pregnancy in 62 studies
nitrogen mustard : Compounds having two beta-haloalkyl groups bound to a nitrogen atom, as in (X-CH2-CH2)2NR.
Pregnancy: The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH.
Excerpt | Relevance | Reference |
---|---|---|
"A case of human fetal renal maldevelopment following the administration of nitrogen mustard, vincristine, procarbazine, and prednisone in early pregnancy for therapy of Hodgkin's disease is reported." | 3.65 | Fetal renal malformation following treatment of Hodgkin's disease during pregnancy. ( Mellman, WJ; Mennuti, MT; Shepard, TH, 1975) |
"The association between Hodgkin's disease and pregnancy is rare." | 2.38 | [Hodgkin's disease and pregnancy. 3 case reports and a review of the literature]. ( Abboud, J; Chahine, G; Nasnas, R; Nasrallah, T, 1993) |
"Twelve women (12%) experienced 13 miscarriages after a median of 50 months (range, 13-120) from the end of therapy." | 1.38 | Impact of different treatment approaches on pregnancy outcomes in 99 women treated for Hodgkin lymphoma. ( Alfò, M; Annechini, G; Cavalieri, E; De Sanctis, V; Enrici, RM; Filippone, FR; Minniti, G; Muni, R; Osti, MF; Pulsoni, A; Valeriani, M, 2012) |
"Hodgkin's disease was diagnosed in a 12-year old boy and a 2-year old his sister whose mother had been treated with repeated cycles of nitrogen mustard for optic neuritis." | 1.30 | [Hodgkin's disease in two children of mother treated with nitrogranulogen]. ( Armata, J; Balwierz, W; Eliasińska, A; Moryl-Bujakowska, A; Tacik, J, 1998) |
"The peak incidence of Hodgkin's disease occurs during the reproductive age, and its association with pregnancy is at a rate of between 1:1,000-1:6,000." | 1.28 | Maternal and foetal outcome following Hodgkin's disease in pregnancy. ( Degendorfer, P; Koren, G; Lishner, M; Panzarella, T; Sutcliffe, SB; Zemlickis, D, 1992) |
"7 of 8 with brain metastases treated by the same modality gave complete remission." | 1.27 | [Combination therapy of advanced choriocarcinoma--an analysis of 60 patients]. ( Cai, SM; Ding, YQ; Wang, RY, 1986) |
"Br." | 1.27 | [Pregnancy and fetal development after therapy of Hodgkin's disease]. ( Slanina, J; Spratler, J; Wannenmacher, M, 1985) |
"Persistent amenorrhea has occurred in 11 of 24 patients (46 percent) treated with MOPP alone or MOPP plus radiation excluding the pelvis." | 1.26 | Long-term follow up of ovarian function in women treated with MOPP chemotherapy for Hodgkin's disease. ( DeVita, VT; Hubbard, SM; Schilsky, RL; Sherins, RJ; Wesley, MN; Young, RC, 1981) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 47 (75.81) | 18.7374 |
1990's | 10 (16.13) | 18.2507 |
2000's | 3 (4.84) | 29.6817 |
2010's | 1 (1.61) | 24.3611 |
2020's | 1 (1.61) | 2.80 |
Authors | Studies |
---|---|
Clark, H | 1 |
Pereira Vera, B | 1 |
Zhang, Z | 1 |
Brayboy, LM | 1 |
De Sanctis, V | 1 |
Filippone, FR | 1 |
Alfò, M | 1 |
Muni, R | 1 |
Cavalieri, E | 1 |
Pulsoni, A | 1 |
Annechini, G | 1 |
Valeriani, M | 1 |
Osti, MF | 1 |
Minniti, G | 1 |
Enrici, RM | 1 |
DEUSCHLE, KW | 1 |
WIGGINS, WS | 1 |
ANDERSON, HE | 1 |
BISGARD, JD | 1 |
GREENE, AM | 1 |
WEBB, GA | 1 |
HENNESSY, JP | 1 |
ROTTINO, A | 1 |
DUFOUR, A | 1 |
ANDRE, P | 1 |
KOGA, K | 1 |
MAEDA, K | 1 |
SANTAMARIA, R | 1 |
GENEZZANI, E | 1 |
GRANATO, G | 1 |
HERTZ, R | 1 |
ROSS, GT | 3 |
LIPSETT, MB | 2 |
SULLI, G | 1 |
GOTTSCHEWSKI, GH | 2 |
HRESCHCHYSHYN, MM | 1 |
PLIESS, G | 1 |
NOLAN, JF | 1 |
COOK, EM | 1 |
DALLKE, WE | 1 |
HETTIG, RA | 1 |
ROBERTSON, GG | 1 |
CLINE, DT | 1 |
van Beek, RD | 1 |
van den Heuvel-Eibrink, MM | 1 |
Laven, JS | 1 |
de Jong, FH | 1 |
Themmen, AP | 1 |
Hakvoort-Cammel, FG | 1 |
van den Bos, C | 1 |
van den Berg, H | 1 |
Pieters, R | 1 |
de Muinck Keizer-Schrama, SM | 1 |
Müller, M | 2 |
Soukup, S | 1 |
Takacs, E | 1 |
Warkany, J | 1 |
Meyne, J | 1 |
Legator, MS | 1 |
Dein, RA | 1 |
Mennuti, MT | 2 |
Kovach, P | 1 |
Gabbe, SG | 1 |
Specht, L | 1 |
Hansen, MM | 1 |
Geisler, C | 1 |
Andrieu, JM | 2 |
Ochoa-Molina, ME | 2 |
Cunningham, J | 1 |
Mauch, P | 1 |
Rosenthal, DS | 1 |
Canellos, GP | 1 |
Schilsky, RL | 1 |
Sherins, RJ | 1 |
Hubbard, SM | 1 |
Wesley, MN | 1 |
Young, RC | 1 |
DeVita, VT | 1 |
Abboud, J | 1 |
Nasrallah, T | 1 |
Chahine, G | 1 |
Nasnas, R | 1 |
Tanaka, T | 1 |
Yamagami, T | 1 |
Oka, Y | 1 |
Nomura, T | 1 |
Sugiyama, H | 1 |
Brice, P | 1 |
Pautier, P | 1 |
Marolleau, JP | 1 |
Castaigne, S | 1 |
Gisselbrecht, C | 1 |
Anasiewicz, A | 1 |
Carlton, DP | 1 |
Albertine, KH | 1 |
Cho, SC | 1 |
Lont, M | 1 |
Bland, RD | 1 |
Armata, J | 1 |
Balwierz, W | 1 |
Tacik, J | 1 |
Moryl-Bujakowska, A | 1 |
Eliasińska, A | 1 |
Maslovsky, I | 1 |
Volchek, L | 1 |
Blumental, R | 1 |
Ducach, A | 1 |
Lugassy, G | 1 |
Avilés, A | 3 |
Neri, N | 1 |
Garrett, MJ | 1 |
Das, S | 1 |
Smith, JD | 1 |
Freedman, LS | 1 |
Johnson, SA | 1 |
Goldman, JM | 1 |
Hawkins, DF | 1 |
Sieber, SM | 1 |
Pascher, F | 1 |
Anderson, D | 1 |
McGregor, DB | 1 |
Purchase, IF | 1 |
Hodge, MC | 1 |
Cuthbert, JA | 1 |
Shepard, TH | 1 |
Mellman, WJ | 1 |
Díaz-Maqueo, JC | 1 |
Talavera, A | 1 |
Guzmán, R | 1 |
García, EL | 1 |
Zepeda, G | 1 |
Cruz, J | 1 |
Lishner, M | 1 |
Zemlickis, D | 1 |
Degendorfer, P | 1 |
Panzarella, T | 1 |
Sutcliffe, SB | 1 |
Koren, G | 1 |
Tournaye, H | 1 |
Camus, M | 1 |
Bollen, N | 1 |
Wisanto, A | 1 |
Van Steirteghem, AC | 1 |
Devroey, P | 1 |
Cai, SM | 1 |
Wang, RY | 1 |
Ding, YQ | 1 |
Sauer, MV | 1 |
Macaso, TM | 1 |
Ishida, EH | 1 |
Giudice, L | 1 |
Marshall, JR | 1 |
Buster, JE | 1 |
Le Pors, P | 1 |
Tschupp, MJ | 1 |
de Queiroz, D | 1 |
Grosbois, B | 1 |
Lemoine, H | 1 |
Grall, JY | 1 |
Slanina, J | 1 |
Wannenmacher, M | 1 |
Spratler, J | 1 |
Shalet, SM | 1 |
Vaughan Williams, CA | 1 |
Whitehead, E | 1 |
Phillips, RF | 1 |
Van Thiel, DH | 1 |
Greenwald, ES | 1 |
Pommatau, E | 1 |
Brunat, M | 1 |
Mayer, H | 1 |
Dargent, M | 1 |
Baum, J | 1 |
Vaughan, J | 1 |
von Kreybig, T | 1 |
Horan, AH | 1 |
Skreb, N | 1 |
Haas, RJ | 1 |
Nagai, S | 1 |
Abiko, S | 1 |
Nakaya, K | 1 |
Numata, F | 1 |
Hayashi, N | 1 |
Robinson, E | 1 |
Ratzkowski, E | 1 |
Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
---|---|---|---|---|---|---|---|
Maternal Cancer Diagnosis and Treatment During Pregnancy:a Registry for Maternal, Fetal, and Neonatal Outcomes With Longitudinal Follow up of Child Development and Maternal Psychological Well Being[NCT02749474] | 400 participants (Anticipated) | Observational [Patient Registry] | 2003-07-31 | Recruiting | |||
[information is prepared from clinicaltrials.gov, extracted Sep-2024] |
7 reviews available for mechlorethamine and Pregnancy
Article | Year |
---|---|
[MEDICAL THERAPY OF MALIGNANT NEOPLASMS].
Topics: Antimetabolites; Antineoplastic Agents; Antiviral Agents; Blood Transfusion; Busulfan; Chlorambucil; | 1964 |
The reproductive potential of young men and women with Hodgkin's disease.
Topics: Adult; Amenorrhea; Antineoplastic Combined Chemotherapy Protocols; Congenital Abnormalities; Female; | 1984 |
[Hodgkin's disease and pregnancy. 3 case reports and a review of the literature].
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Biopsy; Bleomycin; Bone Marrow Examination; C | 1993 |
The action of antitumor agents: a double-edged sword?
Topics: Alkylating Agents; Animals; Antineoplastic Agents; Azathioprine; Burkitt Lymphoma; Choriocarcinoma; | 1977 |
Cancer chemotherapy. 3.
Topics: Abnormalities, Drug-Induced; Alkylating Agents; Allopurinol; Alopecia; Antimetabolites; Antineoplast | 1972 |
Immunosuppressive drugs in rheumatoid arthritis.
Topics: Arthritis, Rheumatoid; Azathioprine; Chlorambucil; Cyclophosphamide; Female; Humans; Immunosuppressi | 1969 |
[Carcinogenesis and teratogenesis. Comparative studies from the viewpoint of teratology].
Topics: Abnormalities, Drug-Induced; Alkylating Agents; Animals; Antineoplastic Agents; Carcinogens; Cycloph | 1970 |
55 other studies available for mechlorethamine and Pregnancy
Article | Year |
---|---|
MDR-1 function protects oocyte mitochondria against the transgenerational effects of nitrogen mustard exposure.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; Chemical Warfare Agents; Female; Loss of Fun | 2020 |
Impact of different treatment approaches on pregnancy outcomes in 99 women treated for Hodgkin lymphoma.
Topics: Abortion, Spontaneous; Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Congenital | 2012 |
The use of nitrogen mustard in the management of two pregnant lymphoma patients.
Topics: Disease Management; Fetus; Hodgkin Disease; Lymphoma; Mechlorethamine; Nitrogen Mustard Compounds; P | 1953 |
Metastatic chorionepithelioma of lung with nitrogen mustard therapy; preliminary report.
Topics: Choriocarcinoma; Female; Lung Neoplasms; Mechlorethamine; Nitrogen Mustard Compounds; Pregnancy; Tro | 1954 |
Adjuvant chemotherapy of choriocarcinoma. Presentation of 2 cases with 5 year survival.
Topics: Chemotherapy, Adjuvant; Choriocarcinoma; Female; Humans; Mechlorethamine; Nitrogen Mustard Compounds | 1962 |
HODGKIN'S DISEASE IN PREGNANCY.
Topics: Female; Hodgkin Disease; Mechlorethamine; Neoplasms; Pregnancy; Pregnancy Complications; Triethylene | 1963 |
[APROPOS OF THE TREATMENT OF TUMORS OF THE TESTICLE].
Topics: Castration; Choriocarcinoma; Dactinomycin; Female; Humans; Lung Neoplasms; Lymphatic Metastasis; Mal | 1963 |
[PRACTICAL ASPECTS OF CHEMOTHERAPY IN HYDATIDIFORM MOLE AND CHORIOCARCINOMA].
Topics: Anti-Bacterial Agents; Antineoplastic Agents; Choriocarcinoma; Cyclophosphamide; Desoxycorticosteron | 1963 |
ALKYLATION OF MYOSIN A AND MYOSIN B BY 2,2'-DICHLORO-N-METHYLDIETHYLAMINEHYDROCHLORIDE.
Topics: Adenosine Triphosphate; Alkylation; Chemical Phenomena; Chemistry; Chloramines; Chlorides; Female; H | 1963 |
CHEMOTHERAPY IN WOMEN WITH TROPHOBLASTIC DISEASE: CHORIOCARCINOMA, CHORIOADENOMA DESTRUENS, AND COMPLICATED HYDATIDIFORM MOLE.
Topics: Antineoplastic Agents; Choriocarcinoma; Cyclophosphamide; Dactinomycin; Female; Humans; Hydatidiform | 1964 |
[THE PATHOGENESIS OF VARIOUS EXTERNAL MALFORMATIONS AS A CONSEQUENCE OF EXOGENOUS STIMULI IN MAMMALS].
Topics: Abnormalities, Drug-Induced; Animals; Cyclophosphamide; Ectromelia; Female; Humans; Lagomorpha; Mamm | 1963 |
MAMMALIAN BLASTOPATHIOS DUE TO DRUGS.
Topics: Abnormalities, Drug-Induced; Animals; Cyclophosphamide; Female; Humans; Mammals; Mechlorethamine; Pr | 1964 |
EXPERIENCES WITH CHEMOTHERAPY IN GYNECOLOGIC CANCER.
Topics: Antineoplastic Agents; Biomedical Research; Chlorambucil; Cyclophosphamide; Dactinomycin; Female; Ge | 1964 |
[DEVELOPMENTAL DISORDER OF THE SKELETON CAUSED BY NITROGEN MUSTARD AND THE EFFECT OF VITAMIN E].
Topics: Abnormalities, Drug-Induced; Bone and Bones; Bone Development; Drug Hypersensitivity; Mechlorethamin | 1964 |
Metastatic pulmonary chorionepithelioma with recovery in two cases.
Topics: Choriocarcinoma; Cobalt; Cobalt Radioisotopes; Female; Lung Neoplasms; Mechlorethamine; Nitrogen Mus | 1955 |
Effects of nitrogen mustard injections on the embryos of pregnant rats.
Topics: Animals; Embryo, Mammalian; Embryo, Nonmammalian; Injections; Mechlorethamine; Nitrogen Mustard Comp | 1950 |
Anti-Mullerian hormone is a sensitive serum marker for gonadal function in women treated for Hodgkin's lymphoma during childhood.
Topics: Adolescent; Adult; Age Factors; Age of Onset; Anti-Mullerian Hormone; Antineoplastic Combined Chemot | 2007 |
Does nitrogen mustard affect the foetus directly or secondarily by its effect on the mother?
Topics: Abnormalities, Drug-Induced; Animals; Female; Fetus; Mechlorethamine; Pregnancy; Pregnancy, Animal; | 1966 |
Chromosome changes in embryos treated with various teratogens.
Topics: Abnormalities, Drug-Induced; Animals; Chlorambucil; Chromosome Aberrations; Diet; Female; Hydroxyure | 1967 |
Clastogenic effects of transplacental exposure of mouse embryos to nitrogen mustard or cyclophosphamide.
Topics: Animals; Chromosome Aberrations; Cyclophosphamide; Female; Maternal-Fetal Exchange; Mechlorethamine; | 1983 |
Ovarian function in young women in long-term remission after treatment for Hodgkin's disease stage I or II.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Estrad | 1984 |
Menstrual cycle, pregnancies and offspring before and after MOPP therapy for Hodgkin's disease.
Topics: Adolescent; Adult; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Drug Thera | 1983 |
[Pregnancies and offspring after MOPP therapy].
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Female; Fertility; Fetus; Hodgkin | 1982 |
Long-term complications of MOPP chemotherapy in patients with Hodgkin's disease.
Topics: Adolescent; Adult; Antineoplastic Agents; Child; Child, Preschool; Drug Therapy, Combination; Female | 1982 |
Long-term follow up of ovarian function in women treated with MOPP chemotherapy for Hodgkin's disease.
Topics: Adolescent; Adult; Amenorrhea; Antineoplastic Agents; Female; Follow-Up Studies; Hodgkin Disease; Ho | 1981 |
The scid mutation in mice causes defects in the repair system for both double-strand DNA breaks and DNA cross-links.
Topics: Animals; Bleomycin; Cell Line; Cell Survival; DNA Damage; DNA Repair; Female; Male; Mechlorethamine; | 1993 |
Pregnancy after autologous bone marrow transplantation for malignant lymphomas.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Carmustine; Cyclophosphamide; Cyt | 1994 |
Teratogenic effects of chlormetine hydrochloride in rats.
Topics: Abnormalities, Drug-Induced; Animals; Antineoplastic Agents, Alkylating; Drug Evaluation, Preclinica | 1996 |
Role of neutrophils in lung vascular injury and edema after premature birth in lambs.
Topics: Alkylating Agents; Animals; Animals, Newborn; Blood Gas Analysis; Extravascular Lung Water; Female; | 1997 |
[Hodgkin's disease in two children of mother treated with nitrogranulogen].
Topics: Alkylating Agents; Child; Female; Hodgkin Disease; Humans; Male; Maternal Welfare; Mechlorethamine; | 1998 |
Persistent paraneoplastic neurologic syndrome after successful therapy of Hodgkin's disease.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Ataxia; Bleomycin; Combined Modality Therapy; | 2001 |
Hematological malignancies and pregnancy: a final report of 84 children who received chemotherapy in utero.
Topics: Acute Disease; Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Behavior; Bleomyci | 2001 |
Long term experience with combination chemotherapy in advanced Hodgkin's disease.
Topics: Adult; Antineoplastic Agents; Bleomycin; Drug Therapy, Combination; Female; Hodgkin Disease; Humans; | 1977 |
Pregnancy after chemotherapy for Hodgkin's disease.
Topics: Adolescent; Adult; Antineoplastic Agents; Child; Drug Administration Schedule; Drug Therapy, Combina | 1979 |
Congenital anomalies among children born of mothers receiving chemotherapy for gestational trophoblastic neoplasms.
Topics: Abnormalities, Drug-Induced; Antineoplastic Agents; Chlorambucil; Drug Therapy, Combination; Female; | 1976 |
Systemic reactions to topically applied drugs.
Topics: Administration, Topical; Adrenal Cortex Hormones; Adult; Aged; Boric Acids; Child; Child, Preschool; | 1978 |
Dominant-lethal test results with known mutagens in two laboratories.
Topics: Animals; Cyclophosphamide; Embryo Implantation; Ethyl Methanesulfonate; Female; Fetal Death; Laborat | 1977 |
Fetal renal malformation following treatment of Hodgkin's disease during pregnancy.
Topics: Abnormalities, Drug-Induced; Abortion, Induced; Adult; Autopsy; Female; Fetus; Hodgkin Disease; Huma | 1975 |
Growth and development of children of mothers treated with chemotherapy during pregnancy: current status of 43 children.
Topics: Acute Disease; Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Behavior; Bleomyci | 1991 |
[Hodgkin's disease during pregnancy. Study of late effects in the newborn infants].
Topics: Abnormalities, Drug-Induced; Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Chrom | 1991 |
Maternal and foetal outcome following Hodgkin's disease in pregnancy.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Birth Weight; Case-Control Studies; Cesarean | 1992 |
In vitro fertilization techniques with frozen-thawed sperm: a method for preserving the progenitive potential of Hodgkin patients.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Cryopreservation; Embryo Transfer; Female; Fe | 1991 |
[Combination therapy of advanced choriocarcinoma--an analysis of 60 patients].
Topics: Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Choriocarcinoma; Combined Modality | 1986 |
Pregnancy following nonsurgical donor ovum transfer to a functionally agonadal woman.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Embryo Transfer; Estradiol; Female; Hodgkin D | 1987 |
[Twin pregnancy after iatrogenic menopause].
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Estrogens; Female; Hodgkin Disease; Humans; I | 1987 |
[Pregnancy and fetal development after therapy of Hodgkin's disease].
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Embryonic and Fetal Develop | 1985 |
Pregnancy after chemotherapy induced ovarian failure.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Female; Hodgkin Disease; Humans; Mechloretham | 1985 |
Cyclophosphamide and the pubertal testis.
Topics: Abortion, Therapeutic; Adolescent; Child; Child, Preschool; Female; Humans; Infant; Mechlorethamine; | 1973 |
Pregnancies after chemotherapy of trophoblastic neoplasms.
Topics: Abortion, Spontaneous; Abruptio Placentae; Antineoplastic Agents; Azo Compounds; Dactinomycin; Deafn | 1970 |
Complete regression of metastatic tumors of the adult with antimitotic treatment.
Topics: Adolescent; Adult; Antineoplastic Agents; Choriocarcinoma; Cyclophosphamide; Dactinomycin; Female; F | 1974 |
The suppression of inflammatory edema at the nidation site by sodium salicylate and nitrogen mustard in the rat.
Topics: Animals; Anti-Inflammatory Agents; Capillary Permeability; Decidua; Depression, Chemical; Dye Diluti | 1971 |
Does nitrogen mustard mimic the x-ray effects in any case?
Topics: Abnormalities, Drug-Induced; Animals; Brain; Eye; Eye Abnormalities; Female; In Vitro Techniques; Me | 1964 |
[The role of cytokinetically resting cells for the regeneration of an aplastic bone marrow. Autoradiographic studies on rat].
Topics: Animals; Animals, Newborn; Autoradiography; Bone Marrow; Bone Marrow Cells; Epithelium; Female; Hema | 1971 |
[Effect of antineoplastic agents on the ovarian function in the patient after excision of hydatidiform mole].
Topics: Adult; Female; Humans; Hydatidiform Mole; Mechlorethamine; Methotrexate; Ovary; Pregnancy | 1967 |
Chemotherapy and immunotherapy of a patient with choriocarcinoma.
Topics: Choriocarcinoma; Female; Freund's Adjuvant; Humans; Leukocytes; Mechlorethamine; Methotrexate; Middl | 1965 |