mechlorethamine has been researched along with Ovarian Neoplasms in 31 studies
nitrogen mustard : Compounds having two beta-haloalkyl groups bound to a nitrogen atom, as in (X-CH2-CH2)2NR.
Ovarian Neoplasms: Tumors or cancer of the OVARY. These neoplasms can be benign or malignant. They are classified according to the tissue of origin, such as the surface EPITHELIUM, the stromal endocrine cells, and the totipotent GERM CELLS.
| Excerpt | Relevance | Reference |
|---|---|---|
| " After a median follow-up of more than 6 years following MOPP (mechlorethamine/vincristine/procarbazine/prednisone) chemotherapy with or without radiotherapy, 5% of patients with Hodgkin's disease developed second primaries, 60% of which were leukemias." | 4.78 | Cytotoxic chemotherapy-induced second primary neoplasms: clinical aspects. ( Petru, E; Schmähl, D, 1991) |
| "Besides human 2008 ovarian cancer cells we also found that human lung (A549) and head and neck cancer cells (SCC 25) were transiently sensitized by cisplatin." | 1.29 | Factors influencing the drug sensitization of human tumor cells for in situ lipofection. ( Huang, L; Son, K, 1996) |
| "Of 602 patients treated for non-Hodgkin's lymphomas, 9 developed overt acute nonlymphocytic leukemia or preleukemia with refractory cytopenia and cytogenetic abnormalities of the bone marrow." | 1.27 | Risk of acute nonlymphocytic leukemia and preleukemia in patients treated with cyclophosphamide for non-Hodgkin's lymphomas. Comparison with results obtained in patients treated for Hodgkin's disease and ovarian carcinoma with other alkylating agents. ( Ersbøll, J; Keiding, N; Larsen, MS; Larsen, SO; Nissen, NI; Pedersen-Bjergaard, J; Philip, P; Schultz, H; Sørensen, HM, 1985) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 28 (90.32) | 18.7374 |
| 1990's | 3 (9.68) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| ULLERY, JC | 1 |
| MULLER, P | 1 |
| GOLDBERG, G | 1 |
| TOUSSAINT, P | 1 |
| MOORE, JG | 1 |
| BRANDKAMP, WW | 1 |
| BURNES, WL | 1 |
| THEISEN, H | 1 |
| GREEN, TH | 1 |
| COONRAD, EV | 1 |
| RUNDLES, RW | 1 |
| ANKENMAN, GJ | 1 |
| BALFOUR, J | 1 |
| MARK, JB | 1 |
| GOLDENBERG, IS | 1 |
| MONTAGUE, AC | 1 |
| SANSON, J | 1 |
| GRUHN, J | 1 |
| SHINGLETON, WW | 1 |
| PARKER, RT | 1 |
| BROWN, FE | 1 |
| WRIGHT, HK | 1 |
| LATHROP, JC | 1 |
| HRESCHCHYSHYN, MM | 1 |
| CONKLIN, JW | 1 |
| UPTON, AC | 1 |
| CHRISTENBERRY, KW | 1 |
| HORNTRICH, J | 1 |
| MASTERSON, JG | 1 |
| MILLER, SP | 1 |
| BRENNER, SM | 1 |
| ANDERMAN, LB | 1 |
| JOHNSON, WM | 1 |
| HOSMER, F | 1 |
| Cornbleet, MA | 1 |
| Leonard, RC | 1 |
| Smyth, JF | 1 |
| Presant, CA | 1 |
| Carr, D | 1 |
| Son, K | 1 |
| Huang, L | 1 |
| Johnson, LP | 1 |
| Rivkin, SE | 1 |
| Weber, EL | 1 |
| Bruntsch, U | 1 |
| Gallmeier, WM | 1 |
| Kolarić, K | 1 |
| Fuss, V | 1 |
| Maricić, Z | 1 |
| Petru, E | 1 |
| Schmähl, D | 1 |
| Frankfurt, OS | 1 |
| Pedersen-Bjergaard, J | 1 |
| Ersbøll, J | 1 |
| Sørensen, HM | 1 |
| Keiding, N | 1 |
| Larsen, SO | 1 |
| Philip, P | 1 |
| Larsen, MS | 1 |
| Schultz, H | 1 |
| Nissen, NI | 1 |
| Griffen, WO | 1 |
| Humphrey, L | 1 |
| Sosin, H | 1 |
| Smith, JP | 1 |
| Rutledge, F | 1 |
| Anderson, CB | 1 |
| Philpott, GW | 1 |
| Ferguson, TB | 1 |
3 reviews available for mechlorethamine and Ovarian Neoplasms
| Article | Year |
|---|---|
High-dose alkylating agent therapy: a review of clinical experiences.
Topics: Alkylating Agents; Busulfan; Carcinoma, Bronchogenic; Carmustine; Dose-Response Relationship, Drug; | 1984 |
Cytotoxic chemotherapy-induced second primary neoplasms: clinical aspects.
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Female; Hod | 1991 |
The prognosis and management of recurrent abdominal malignancies.
Topics: Abdominal Neoplasms; Adolescent; Adult; Antineoplastic Agents; Bile Duct Neoplasms; Chemotherapy, Ca | 1969 |
28 other studies available for mechlorethamine and Ovarian Neoplasms
| Article | Year |
|---|---|
Treatment of pelvic malignancy.
Topics: Cobalt; Cobalt Radioisotopes; Female; Gold Radioisotopes; Humans; Mechlorethamine; Neoplasms; Nitrog | 1957 |
[Use of nitrogen mustard derivatives in palliative therapy of genital cancers with special reference to ovarian tumors in advanced stages].
Topics: Female; Genitalia; Genitalia, Female; Humans; Mechlorethamine; Neoplasms; Nitrogen Mustard Compounds | 1958 |
Evaluation of chemotherapy in ovarian and cervical cancer by tissue culture methods.
Topics: Antineoplastic Agents; Busulfan; Female; Humans; Mechlorethamine; Neoplasms; Nitrogen Mustard Compou | 1959 |
[Regression of a metastasizing disgerminoma by cytostatic drug therapy].
Topics: Cytostatic Agents; Dysgerminoma; Female; Humans; Mechlorethamine; Neoplasms; Nitrogen Mustard Compou | 1959 |
Hemisulfur mustard in the palliation of patients with metastatic ovarian carcinoma.
Topics: Antineoplastic Agents; Carcinoma, Ovarian Epithelial; Female; Humans; Mechlorethamine; Mustard Gas; | 1959 |
Mustard chemotherapy in ovarian carcinoma.
Topics: Antineoplastic Agents; Female; Humans; Mechlorethamine; Mustard Plant; Neoplasms; Nitrogen Mustard C | 1959 |
Nitrogen mustard in treatment of metastatic carcinoma of the testis.
Topics: Choriocarcinoma; Dysgerminoma; Female; Humans; Male; Mechlorethamine; Nitrogen Mustard Compounds; Ov | 1961 |
Cases from the medical grand rounds, Case 446 tumor perfusion. Massachusetts General Hospital.
Topics: Female; Hospitals, General; Humans; Massachusetts; Mechlorethamine; Neoplasms; Nitrogen Mustard Comp | 1959 |
INTRAPLEURAL MECHLORETHAMINE HYDROCHLORIDE THERAPY FOR MALIGNANT PLEURAL EFFUSION.
Topics: Breast Neoplasms; Drainage; Female; Humans; Lung Neoplasms; Lymphoma; Mechlorethamine; Neoplasm Meta | 1964 |
SPONTANEOUS ENDOGENOUS CLOSTRIDIAL SEPTICEMIA.
Topics: Antiemetics; Chloramphenicol; Clostridium; Clostridium perfringens; Diabetes Mellitus; Electrocardio | 1964 |
ABDOMINAL PERFUSION FOR CANCER CHEMOTHERAPY USING HYPOTHERMIA AND HYPERTHERMIA.
Topics: Abdomen; Antineoplastic Agents; Chemotherapy, Cancer, Regional Perfusion; Colonic Neoplasms; Cycloph | 1964 |
INTERNAL FLUID SHIFTS SECONDARY TO INTRAPERITONEAL NITROGEN MUSTARD.
Topics: Abdominal Neoplasms; Animals; Body Fluids; Dogs; Female; Fluid Shifts; Hematocrit; Humans; Injection | 1964 |
PERFUSION CHEMOTHERAPY FOR GYNECOLOGICAL MALIGNANCY.
Topics: Adenocarcinoma; Carcinoma, Squamous Cell; Chemotherapy, Cancer, Regional Perfusion; Fallopian Tube N | 1963 |
EXPERIENCES WITH CHEMOTHERAPY IN GYNECOLOGIC CANCER.
Topics: Antineoplastic Agents; Biomedical Research; Chlorambucil; Cyclophosphamide; Dactinomycin; Female; Ge | 1964 |
FURTHER OBSERVATIONS ON LATE SOMATIC EFFECTS OF RADIOMIMETIC CHEMICALS AND X-RAYS IN MICE.
Topics: Aging; Busulfan; Cataract; Female; Humans; Leukemia; Leukemia, Myeloid; Longevity; Lung Neoplasms; L | 1965 |
[Successful therapy of a metastasizing seminoma with nitrogen mustard N-oxide].
Topics: Dysgerminoma; Female; Humans; Male; Mechlorethamine; Neoplasms; Neoplasms, Germ Cell and Embryonal; | 1960 |
The adjuvant chemotherapy study in cancer of the ovary.
Topics: Biomedical Research; Chemotherapy, Adjuvant; Female; Humans; Mechlorethamine; Neoplasms; Nitrogen Mu | 1962 |
Combination therapy with cobalt-60 and chlorambucil in the treatment of disseminated ovarian carcinomatosis.
Topics: Carcinoma; Chlorambucil; Cobalt; Cobalt Radioisotopes; Combined Modality Therapy; Female; Humans; Me | 1962 |
Dysgerminoma treated with nitrogen mustard.
Topics: Dysgerminoma; Female; Humans; Mechlorethamine; Nitrogen Mustard Compounds; Ovarian Neoplasms | 1952 |
Amphotericin B (Fungizone R) enhancement of nitrogen mustard uptake by human tumor cells.
Topics: Amphotericin B; Biological Transport; Carcinoma, Squamous Cell; Carrier Proteins; Cells, Cultured; C | 1980 |
Factors influencing the drug sensitization of human tumor cells for in situ lipofection.
Topics: Animals; Antineoplastic Agents; Bleomycin; Cation Exchange Resins; Chloramphenicol O-Acetyltransfera | 1996 |
Palliation in malignant pleural effusion.
Topics: Adenocarcinoma; Adult; Aged; Breast Neoplasms; Drainage; Female; Hodgkin Disease; Humans; Lung Neopl | 1975 |
[Chemotherapy of the ovarian carcinoma (author's transl)].
Topics: Altretamine; Antineoplastic Agents; Chlorambucil; Cisplatin; Cyclophosphamide; Doxorubicin; Drug The | 1977 |
[Experience with intracavital administration of nitrogen mustard in the treatment of malignant pleural effusions].
Topics: Adult; Aged; Breast Neoplasms; Bronchial Neoplasms; Female; Humans; Male; Mechlorethamine; Middle Ag | 1975 |
Decreased stability of DNA in cells treated with alkylating agents.
Topics: Alkylating Agents; Antibodies, Monoclonal; Antibody Specificity; Deoxyribonucleases; DNA Damage; DNA | 1990 |
Risk of acute nonlymphocytic leukemia and preleukemia in patients treated with cyclophosphamide for non-Hodgkin's lymphomas. Comparison with results obtained in patients treated for Hodgkin's disease and ovarian carcinoma with other alkylating agents.
Topics: Acute Disease; Adolescent; Adult; Aged; Alkylating Agents; Antineoplastic Combined Chemotherapy Prot | 1985 |
Chemotherapy in the treatment of cancer of the ovary.
Topics: Adenocarcinoma; Adenocarcinoma, Mucinous; Cyclophosphamide; Cystadenocarcinoma; Dactinomycin; Female | 1970 |
The treatment of malignant pleural effusions.
Topics: Adenocarcinoma; Adolescent; Adult; Aged; Breast Neoplasms; Carcinoma, Small Cell; Carcinoma, Squamou | 1974 |