Page last updated: 2024-10-30

mechlorethamine and Ovarian Diseases

mechlorethamine has been researched along with Ovarian Diseases in 9 studies

nitrogen mustard : Compounds having two beta-haloalkyl groups bound to a nitrogen atom, as in (X-CH2-CH2)2NR.

Ovarian Diseases: Pathological processes of the OVARY.

Research Excerpts

ExcerptRelevanceReference
"Fourteen had Hodgkin's and four non-Hodgkin's lymphoma."2.68Prevention of irreversible chemotherapy-induced ovarian damage in young women with lymphoma by a gonadotrophin-releasing hormone agonist in parallel to chemotherapy. ( Avivi, I; Ben-Shahar, M; Blumenfeld, Z; Epelbaum, R; Haim, N; Linn, S, 1996)
"The progeny of patients treated for Hodgkin's disease appear normal and no excess fetal wastage has been noted."1.28Gonadal status and reproductive function following treatment for Hodgkin's disease in childhood: the Stanford experience. ( Donaldson, SS; Ortin, TT; Shostak, CA, 1990)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19904 (44.44)18.7374
1990's4 (44.44)18.2507
2000's0 (0.00)29.6817
2010's1 (11.11)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Conway, JL1
Connors, JM1
Tyldesley, S1
Savage, KJ1
Campbell, BA1
Zheng, YY1
Hamm, J1
Pickles, T1
Dein, RA1
Mennuti, MT1
Kovach, P1
Gabbe, SG1
Whitehead, E2
Shalet, SM2
Jones, PH1
Beardwell, CG1
Deakin, DP1
Bokemeyer, C1
Schmoll, HJ1
van Rhee, J1
Kuczyk, M1
Schuppert, F1
Poliwoda, H1
Blumenfeld, Z2
Avivi, I1
Linn, S1
Epelbaum, R1
Ben-Shahar, M2
Haim, N2
Ritter, M1
Shen-Orr, Z1
Shariki, K1
Ortin, TT1
Shostak, CA1
Donaldson, SS1
Bakchine, H1
Brauner, R1
Thibaud, E1
Rappaport, R1
Flamant, F1
Griscelli, C1
Lemerle, J1
Schaison, G1
Schweisguth, O1
Zucker, JM1
Vaughan Williams, CA1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Ovarian Tissue Freezing For Fertility Preservation In Women Facing A Fertility Threatening Medical Diagnosis Or Treatment Regimen: A Study By The National Physicians Cooperative of the Oncofertility Consortium At Northwestern University[NCT00902720]Phase 425 participants (Anticipated)Interventional2009-05-31Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for mechlorethamine and Ovarian Diseases

ArticleYear
The reproductive potential of young men and women with Hodgkin's disease.
    Obstetrical & gynecological survey, 1984, Volume: 39, Issue:8

    Topics: Adult; Amenorrhea; Antineoplastic Combined Chemotherapy Protocols; Congenital Abnormalities; Female;

1984

Trials

2 trials available for mechlorethamine and Ovarian Diseases

ArticleYear
Prevention of irreversible chemotherapy-induced ovarian damage in young women with lymphoma by a gonadotrophin-releasing hormone agonist in parallel to chemotherapy.
    Human reproduction (Oxford, England), 1996, Volume: 11, Issue:8

    Topics: Adolescent; Adult; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Antineoplastic Combined

1996
Inhibin A concentrations in the sera of young women during and after chemotherapy for lymphoma: correlation with ovarian toxicity.
    American journal of reproductive immunology (New York, N.Y. : 1989), 1998, Volume: 39, Issue:1

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Combined Modality Ther

1998

Other Studies

6 other studies available for mechlorethamine and Ovarian Diseases

ArticleYear
Secondary Breast Cancer Risk by Radiation Volume in Women With Hodgkin Lymphoma.
    International journal of radiation oncology, biology, physics, 2017, 01-01, Volume: 97, Issue:1

    Topics: Adolescent; Adult; Analysis of Variance; Antineoplastic Agents; Antineoplastic Combined Chemotherapy

2017
Gonadal function after combination chemotherapy for Hodgkin's disease in childhood.
    Archives of disease in childhood, 1982, Volume: 57, Issue:4

    Topics: Adolescent; Antineoplastic Agents; Child; Child, Preschool; Drug Therapy, Combination; Female; Hodgk

1982
Long-term gonadal toxicity after therapy for Hodgkin's and non-Hodgkin's lymphoma.
    Annals of hematology, 1994, Volume: 68, Issue:3

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Cyclop

1994
Gonadal status and reproductive function following treatment for Hodgkin's disease in childhood: the Stanford experience.
    International journal of radiation oncology, biology, physics, 1990, Volume: 19, Issue:4

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Combined Modali

1990
[Chemotherapy and ovarian function. Retrospective analysis in 17 girls treated for malignant tumor or hematologic disease].
    Archives francaises de pediatrie, 1986, Volume: 43, Issue:8

    Topics: Adolescent; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Pre

1986
Pregnancy after chemotherapy induced ovarian failure.
    British medical journal (Clinical research ed.), 1985, Mar-23, Volume: 290, Issue:6472

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Female; Hodgkin Disease; Humans; Mechloretham

1985