mechlorethamine has been researched along with Optic Neuritis in 1 studies
nitrogen mustard : Compounds having two beta-haloalkyl groups bound to a nitrogen atom, as in (X-CH2-CH2)2NR.
Optic Neuritis: Inflammation of the optic nerve. Commonly associated conditions include autoimmune disorders such as MULTIPLE SCLEROSIS, infections, and granulomatous diseases. Clinical features include retro-orbital pain that is aggravated by eye movement, loss of color vision, and contrast sensitivity that may progress to severe visual loss, an afferent pupillary defect (Marcus-Gunn pupil), and in some instances optic disc hyperemia and swelling. Inflammation may occur in the portion of the nerve within the globe (neuropapillitis or anterior optic neuritis) or the portion behind the globe (retrobulbar neuritis or posterior optic neuritis).
| Excerpt | Relevance | Reference |
|---|---|---|
| "Hodgkin's disease was diagnosed in a 12-year old boy and a 2-year old his sister whose mother had been treated with repeated cycles of nitrogen mustard for optic neuritis." | 1.30 | [Hodgkin's disease in two children of mother treated with nitrogranulogen]. ( Armata, J; Balwierz, W; Eliasińska, A; Moryl-Bujakowska, A; Tacik, J, 1998) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Armata, J | 1 |
| Balwierz, W | 1 |
| Tacik, J | 1 |
| Moryl-Bujakowska, A | 1 |
| Eliasińska, A | 1 |
1 other study available for mechlorethamine and Optic Neuritis
| Article | Year |
|---|---|
[Hodgkin's disease in two children of mother treated with nitrogranulogen].
Topics: Alkylating Agents; Child; Female; Hodgkin Disease; Humans; Male; Maternal Welfare; Mechlorethamine; | 1998 |