mechlorethamine has been researched along with Optic Nerve Diseases in 2 studies
nitrogen mustard : Compounds having two beta-haloalkyl groups bound to a nitrogen atom, as in (X-CH2-CH2)2NR.
Optic Nerve Diseases: Conditions which produce injury or dysfunction of the second cranial or optic nerve, which is generally considered a component of the central nervous system. Damage to optic nerve fibers may occur at or near their origin in the retina, at the optic disk, or in the nerve, optic chiasm, optic tract, or lateral geniculate nuclei. Clinical manifestations may include decreased visual acuity and contrast sensitivity, impaired color vision, and an afferent pupillary defect.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The first child had hydrocephalus with an enhancing mass at the hypothalamus which followed the optic radiation to include the lateral geniculate body and medial temporal lobe." | 2.38 | Chemotherapeutic treatment of extensive optic pathway tumors in infants. ( Kretschmar, CS; Linggood, RM, 1991) |
| "This case of optic neuropathy is supposed to be a rare example of involvement of the 2nd cranial nerve due to vinca alkaloids." | 1.27 | Transient optic neuropathy secondary to MOPP chemotherapy in Hodgkin's disease: report of a case. ( Guidelli Guidi, S; Maccolini, E; Oddo Bravetti, G; Serra, L; Vecchi, V, 1984) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (50.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Vecchi, V | 1 |
| Maccolini, E | 1 |
| Oddo Bravetti, G | 1 |
| Guidelli Guidi, S | 1 |
| Serra, L | 1 |
| Kretschmar, CS | 1 |
| Linggood, RM | 1 |
1 review available for mechlorethamine and Optic Nerve Diseases
| Article | Year |
|---|---|
Chemotherapeutic treatment of extensive optic pathway tumors in infants.
Topics: Antineoplastic Combined Chemotherapy Protocols; Ascites; Astrocytoma; Cerebrospinal Fluid Shunts; Ci | 1991 |
1 other study available for mechlorethamine and Optic Nerve Diseases
| Article | Year |
|---|---|
Transient optic neuropathy secondary to MOPP chemotherapy in Hodgkin's disease: report of a case.
Topics: Antineoplastic Combined Chemotherapy Protocols; Child; Female; Hodgkin Disease; Humans; Mechloretham | 1984 |