mechlorethamine has been researched along with Nephrotic Syndrome in 41 studies
nitrogen mustard : Compounds having two beta-haloalkyl groups bound to a nitrogen atom, as in (X-CH2-CH2)2NR.
Nephrotic Syndrome: A condition characterized by severe PROTEINURIA, greater than 3.5 g/day in an average adult. The substantial loss of protein in the urine results in complications such as HYPOPROTEINEMIA; generalized EDEMA; HYPERTENSION; and HYPERLIPIDEMIAS. Diseases associated with nephrotic syndrome generally cause chronic kidney dysfunction.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Mechlorethamine has been assessed in 28 patients with idiopathic nephrotic syndrome previously treated with prednisone only." | 7.67 | [Effect of mechlorethamine in idiopathic nephrotic syndrome in childhood]. ( Canals, MJ; Cervera, A; Gómez Campderá, FJ; Gómez Campderá, J; López Gómez, JM; Luque, A; Morales, JL, 1984) |
| "Mechlorethamine has been assessed in 28 patients with idiopathic nephrotic syndrome previously treated with prednisone only." | 3.67 | [Effect of mechlorethamine in idiopathic nephrotic syndrome in childhood]. ( Canals, MJ; Cervera, A; Gómez Campderá, FJ; Gómez Campderá, J; López Gómez, JM; Luque, A; Morales, JL, 1984) |
| "Approximately 30% of children with focal segmental glomerulosclerosis enter remission following treatment with corticosteroids." | 2.38 | Immunosuppressive therapy in the nephrotic syndrome in children. ( Trompeter, RS, 1989) |
| "Children with systemic lupus erythematosus and nephritis may benefit from the addition of cytotoxic agents to their corticosteroid regime, although the indications for this are not clear, and controlled evidence is lacking." | 2.36 | Immunosuppressive agents in the treatment of the nephrotic syndrome and glomerulonephritis in children. ( Cameron, JS, 1979) |
| "The nephrotic syndrome is a rare complication of Hodgkin's disease." | 1.30 | [Clinical case of the month. The association of Hodgkin's disease and nephrotic syndrome]. ( Baron, F; Beguin, Y; Fassotte, MF; Fillet, G; Hermanne, JP, 1998) |
| "The association of Hodgkin's disease and minimal-change nephrotic syndrome is well established." | 1.29 | The successful treatment of recurrent nephrotic syndrome with the MOPP regimen in a patient with a remote history of Hodgkin's disease. ( Delmez, JA; Kissane, JM; Safdar, SH, 1994) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 35 (85.37) | 18.7374 |
| 1990's | 5 (12.20) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (2.44) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Yang, Y | 1 |
| Zhao, L | 1 |
| Xiao, L | 1 |
| Liang, Y | 1 |
| Wang, C | 1 |
| Fu, X | 1 |
| Zhu, X | 2 |
| Yuan, S | 1 |
| Zhu, J | 1 |
| Liu, Y | 1 |
| Li, J | 1 |
| Luo, J | 1 |
| Liu, F | 1 |
| Sun, L | 1 |
| KELLEY, VC | 1 |
| PANOS, TC | 1 |
| GREENMAN, L | 1 |
| WEIGAND, FA | 1 |
| DANOWSKI, TS | 1 |
| DURAND, P | 1 |
| DE TONI, E | 1 |
| WEST, CD | 1 |
| LAGRUE, G | 6 |
| FONTAINE, JL | 1 |
| SAMARCQ, P | 2 |
| FRITEL, D | 3 |
| MILLIEZ, P | 6 |
| CHU, TC | 1 |
| STIRPARO, JA | 1 |
| WU, C | 2 |
| TALAMO, RC | 1 |
| CRAWFORD, JD | 1 |
| ISASA, FA | 1 |
| COLDBECK, JH | 1 |
| BARIETY, J | 3 |
| SAFAR, M | 1 |
| HESSE, JC | 1 |
| ANAGNOSTOPOULOS, T | 1 |
| PERLINSKA SCHNEIDER, L | 1 |
| GUTKA, A | 1 |
| TAYLOR, RD | 2 |
| LAROCHE, C | 1 |
| CORCORAN, AC | 1 |
| PAGE, IH | 1 |
| Soyka, LF | 1 |
| Gómez Campderá, FJ | 1 |
| López Gómez, JM | 1 |
| Cervera, A | 1 |
| Gómez Campderá, J | 1 |
| Canals, MJ | 1 |
| Morales, JL | 1 |
| Luque, A | 1 |
| Schoeneman, MJ | 1 |
| Spitzer, A | 1 |
| Greifer, I | 1 |
| Rose, GM | 1 |
| Delmez, JA | 1 |
| Safdar, SH | 1 |
| Kissane, JM | 1 |
| Arumugam, R | 1 |
| Watson, AR | 1 |
| Tune, BM | 1 |
| Mendoza, SA | 1 |
| Baron, F | 1 |
| Hermanne, JP | 1 |
| Fassotte, MF | 1 |
| Beguin, Y | 1 |
| Fillet, G | 1 |
| Cameron, JS | 1 |
| Fine, BP | 1 |
| Munoz, R | 1 |
| Uy, CS | 1 |
| Ty, A | 1 |
| Imiela, J | 1 |
| Nowaczyk, M | 1 |
| Małecki, R | 1 |
| Górski, A | 1 |
| Trompeter, RS | 1 |
| Wang, XZ | 1 |
| Cheng, CX | 1 |
| Gordillo-Paniagua, G | 1 |
| Mora-Muñoz, A | 1 |
| Herrera-Garnica, J | 1 |
| Gordillo-de Anda, R | 1 |
| Muñoz-Arizpe, R | 1 |
| Habib, R | 1 |
| Levy, M | 1 |
| Lokich, JJ | 1 |
| Galvanek, EG | 1 |
| Moloney, WC | 1 |
| de ndrade, DF | 1 |
| Paolucci, AA | 1 |
| Pimenta, L | 1 |
| Orsini, A | 1 |
| Pierron, H | 1 |
| Unal, D | 1 |
| Nowak, S | 1 |
| Bodalski, J | 1 |
| Margolis, A | 1 |
| Michalak, A | 1 |
| Jacquillat, C | 1 |
2 reviews available for mechlorethamine and Nephrotic Syndrome
| Article | Year |
|---|---|
Immunosuppressive agents in the treatment of the nephrotic syndrome and glomerulonephritis in children.
Topics: Azathioprine; Child; Chlorambucil; Cyclophosphamide; Glomerulonephritis; Humans; Immunosuppressive A | 1979 |
Immunosuppressive therapy in the nephrotic syndrome in children.
Topics: Adrenal Cortex Hormones; Child; Child, Preschool; Chlorambucil; Cyclophosphamide; Cyclosporins; Glom | 1989 |
1 trial available for mechlorethamine and Nephrotic Syndrome
| Article | Year |
|---|---|
Nitrogen mustard therapy and nephrotic syndrome.
Topics: Alkylating Agents; Child, Preschool; Drug Resistance; Female; Humans; Infant; Male; Mechlorethamine; | 1996 |
38 other studies available for mechlorethamine and Nephrotic Syndrome
| Article | Year |
|---|---|
Chlormethine Hydrochloride is Not Inferior to Tacrolimus in Treating Steroid-Resistant Nephrotic Syndrome.
Topics: Adult; Drug Resistance; Female; Humans; Male; Mechlorethamine; Nephrotic Syndrome; Remission Inducti | 2018 |
The nephrotic syndrome in children. I. Clinical response to nitrogen mustard therapy.
Topics: Child; Humans; Infant; Mechlorethamine; Nephrosis; Nephrotic Syndrome; Nitrogen Mustard Compounds | 1952 |
Therapy of the nephrotic syndrome: sodium restriction, dextran, and corticotropin (ACTH) alone or combined with nitrogen mustard.
Topics: Adrenocorticotropic Hormone; Dextrans; Ions; Mechlorethamine; Nephrosis; Nephrotic Syndrome; Nitroge | 1955 |
Treatment of nephrotic syndrome in children.
Topics: Adrenocorticotropic Hormone; Child; Hyperthermia, Induced; Infant; Mechlorethamine; Nephrosis; Nephr | 1955 |
Use of combined hormone and mechlorethamine (nitrogen mustard) therapy in lipoid nephrosis.
Topics: Adrenocorticotropic Hormone; Child; Humans; Infant; Mechlorethamine; Nephrosis, Lipoid; Nephrotic Sy | 1958 |
[Treatment of nephrotic syndromes with nitrogen mustards].
Topics: Mechlorethamine; Nephrotic Syndrome; Nitrogen Mustard Compounds | 1961 |
[Nitrogen mustard in chronic nephrotic syndrome].
Topics: Mechlorethamine; Nephrotic Syndrome; Nitrogen Mustard Compounds | 1959 |
[Nephrotic syndrome. Current concept. Our experience in its treatment, especially with nitrogen mustards].
Topics: Mechlorethamine; Nephrotic Syndrome; Nitrogen Mustard Compounds | 1960 |
[Nitrogen mustard in the treatment of the nephrotic syndrome of chronic glomerulonephritis].
Topics: Chronic Disease; Glomerulonephritis; Mechlorethamine; Nephrotic Syndrome; Nitrogen Mustard Compounds | 1959 |
[Nitrogen mustard in treatment of nephrotic syndrome of chronic glomerulonephritis].
Topics: Chronic Disease; Glomerulonephritis; Mechlorethamine; Nephrotic Syndrome; Nitrogen Mustard Compounds | 1959 |
Trimethadione nephrosis treated with cortisone and nitrogen mustard.
Topics: Anticonvulsants; Cortisone; Humans; Mechlorethamine; Nephrosis; Nephrotic Syndrome; Trimethadione | 1963 |
[DIAGNOSTIC AND THERAPEUTIC MANAGEMENT OF THE NEPHROTIC SYNDROMES OF INFANCY].
Topics: Adrenal Cortex Hormones; Anti-Bacterial Agents; Antibiotics, Antitubercular; Blood Protein Disorders | 1963 |
EXPERIENCE WITH ALKYLATING AGENTS IN THE TREATMENT OF CHILDREN WITH THE NEPHROTIC SYNDROME.
Topics: Alkylating Agents; Child; Cyclophosphamide; Humans; Mechlorethamine; Nephrotic Syndrome; Proteinuria | 1963 |
[THE NEPHROTIC SYNDROME OF "RHEUMATOID PURPURA"].
Topics: Abdomen; Abdomen, Acute; Abdominal Cavity; Child; Chlorambucil; Diagnosis; Glomerulonephritis; Hemat | 1964 |
[TREATMENT OF THE IDIOPATHIC NEPHROTIC SYNDROME IN CHILDREN].
Topics: Adrenal Cortex Hormones; Anti-Bacterial Agents; Antibiotics, Antitubercular; Child; Chlorothiazide; | 1964 |
[NITROGRANULOGEN IN THE TREATMENT OF NEPHROTIC SYNDROME].
Topics: Drug Therapy; Humans; Mechlorethamine; Nephrotic Syndrome; Nitrogen Mustard Compounds | 1965 |
Nephrotic syndrome: treatment with ACTH and nitrogen mustard.
Topics: Adrenocorticotropic Hormone; Glomerulonephritis; Humans; Mechlorethamine; Nephrosis; Nephrotic Syndr | 1955 |
[The treatment of nephrotic syndromes with nitrogen mustards].
Topics: Humans; Mechlorethamine; Nephrotic Syndrome; Nitrogen Mustard Compounds | 1960 |
[Treatment of the nephrotic syndrome with nitrogen mustard].
Topics: Humans; Mechlorethamine; Nephrotic Syndrome; Nitrogen Mustard Compounds | 1962 |
Treatment of the nephrotic syndrome with nitrogen mustard.
Topics: Glomerulonephritis; Mechlorethamine; Nephrotic Syndrome; Nitrogen Mustard Compounds | 1950 |
The nephrotic syndrome: current concepts in diagnosis and therapy advantages of alternate day steroid regimen.
Topics: Alkylating Agents; Anti-Bacterial Agents; Child; Child, Preschool; Ethacrynic Acid; Humans; Hydralaz | 1967 |
[Effect of mechlorethamine in idiopathic nephrotic syndrome in childhood].
Topics: Child; Child, Preschool; Chlorambucil; Cyclophosphamide; Drug Tolerance; Female; Glomerulosclerosis, | 1984 |
Nitrogen mustard therapy in children with frequent-relapsing nephrotic syndrome and steroid toxicity.
Topics: Child, Preschool; Female; Glucocorticoids; Humans; Infant; Male; Mechlorethamine; Nephrotic Syndrome | 1983 |
Therapy for the child with nephrotic syndrome.
Topics: Adrenal Cortex Hormones; Child; Chlorambucil; Cyclophosphamide; Humans; Mechlorethamine; Nephrotic S | 1982 |
The successful treatment of recurrent nephrotic syndrome with the MOPP regimen in a patient with a remote history of Hodgkin's disease.
Topics: Antineoplastic Combined Chemotherapy Protocols; Hodgkin Disease; Humans; Male; Mechlorethamine; Midd | 1994 |
Nitrogen mustard therapy of pediatric nephrotic syndrome.
Topics: Alkylating Agents; Child; Drug Resistance; Humans; Mechlorethamine; Nephrosis, Lipoid; Nephrotic Syn | 1996 |
[Clinical case of the month. The association of Hodgkin's disease and nephrotic syndrome].
Topics: Adult; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineop | 1998 |
Nitrogen mustard therapy in children with nephrotic syndrome unresponsive to corticosteroid therapy.
Topics: Biopsy; Child; Child, Preschool; Female; Humans; Male; Mechlorethamine; Nephrotic Syndrome; Predniso | 1976 |
[Successful nitrogranulogen treatment of severe nephrotic syndrome in glomerulonephritis--case report].
Topics: Drug Therapy, Combination; Female; Glomerulonephritis, Membranoproliferative; Humans; Kidney Glomeru | 1992 |
[Observations on traditional Chinese medicine and Western medicine therapy in treating 124 nephrotic syndrome patients and controls].
Topics: Adolescent; Child; Cyclophosphamide; Drug Therapy, Combination; Female; Humans; Male; Mechlorethamin | 1986 |
[Nitrogen mustard as an alternative therapy in children with idiopathic nephrotic syndrome and recurrent infections].
Topics: Bacterial Infections; Child; Child, Preschool; Humans; Male; Mechlorethamine; Nephrotic Syndrome; Pr | 1988 |
[Nephropathies of rheumatoid purpura in children. Clinical and anatomical study of 60 cases].
Topics: Adolescent; Child; Child, Preschool; Chlorambucil; Diagnosis, Differential; Female; Fluorescent Anti | 1972 |
Nephrosis of Hodgkin disease. An immune complex-induced lesion.
Topics: Antigen-Antibody Complex; Basement Membrane; Biopsy; Blood Urea Nitrogen; Body Weight; Capillaries; | 1973 |
[Recovery of normal ultrastructure in 2 cases of primary glomerulonephritis with diffuse extra-membranous deposits].
Topics: Adult; Basement Membrane; Biopsy; Chlorambucil; Female; Glomerulonephritis; Glucocorticoids; Hematur | 1968 |
[Treatment of nephrotic syndrome with nitrogen mustard].
Topics: Adolescent; Adult; Child; Child, Preschool; Female; Humans; Male; Mechlorethamine; Nephrotic Syndrom | 1967 |
[Attempt at treatment of idiopathic nephrotic syndrome in children by brief cortisone therapy eventually alternated with an immunodepressor therapy].
Topics: Adolescent; Age Factors; Child; Child, Preschool; Chlorambucil; Drug Synergism; Female; Humans; Male | 1968 |
[Attempts of the use of cytostatic agents in some forms of glomerulonephritis in children].
Topics: Adolescent; Antineoplastic Agents; Azathioprine; Child; Child, Preschool; Chlorambucil; Chronic Dise | 1969 |
[Extended chemotherapy of nephrotic syndromes and of certain glomerular nephropathies].
Topics: Chlorambucil; Glomerulonephritis; Humans; Mechlorethamine; Nephrotic Syndrome | 1965 |