Page last updated: 2024-10-30

mechlorethamine and Mediastinal Neoplasms

mechlorethamine has been researched along with Mediastinal Neoplasms in 47 studies

nitrogen mustard : Compounds having two beta-haloalkyl groups bound to a nitrogen atom, as in (X-CH2-CH2)2NR.

Mediastinal Neoplasms: Tumors or cancer of the MEDIASTINUM.

Research Excerpts

ExcerptRelevanceReference
"9 years, range, 1-15 years) received the AIEOP-MH 1983 Hodgkin disease protocol of low-dose radiation therapy (20-25 Gy), with three cycles of adriamycin, bleomycin, vinblastine, and imidazole carboxamide (ABVD) for children with early-stage and favorable disease, and with alternating cycles of an eight non-cross-resistant drug combination regimen (nitrogen mustard, vincristine, procarbazine, and prednisone [MOPP]/ABVD) for 6 months for those with bulky and unfavorable disease."5.07Treatment of pediatric Hodgkin disease tailored to stage, mediastinal mass, and age. An Italian (AIEOP) multicenter study on 215 patients. ( Bontempi, N; Burnelli, R; Carli, M; Comelli, A; Di Tullio, MT; Pileri, S; Rosati, D; Sotti, G; Testi, AM; Vecchi, V, 1993)
"Eighty patients presented with Hodgkin's disease and a mediastinal mass greater than one third the greatest chest diameter on chest radiograph."2.68Alternating MOPP and ABVD chemotherapy plus mantle-field radiation therapy in patients with massive mediastinal Hodgkin's disease. ( Bastian, AW; DeVita, VT; Duffey, PL; Glatstein, E; Hubbard, SM; Ihde, DC; Jaffe, ES; Longo, DL; Wilson, WH; Wittes, RE; Young, RC, 1997)
"We reviewed all reported cases of Burkitt's lymphoma and/or Burkitt's leukemia (BLL) occurring following therapy for Hodgkin's disease."2.39Burkitt's lymphoma-leukemia in patients treated for Hodgkin's disease. ( Cooper, DL; Levy, A; Salloum, E; Tallini, G, 1996)
"Of the 13 cases, 5 were Hodgkin's disease (HD), and 8 were non-Hodgkin's lymphoma (NHL)."1.33[Clinical analysis of reactive thymic hyperplasia following chemotherapy for childhood malignant lymphoma]. ( Ling, JY; Sun, XF; Wang, ZH; Xia, Y; Zhen, ZJ, 2006)
"Management of Hodgkin's disease (HD) and large mediastinal adenopathy (LMA) usually includes intensive chemotherapy (CT) with or without radiation therapy (XT) regardless of stage."1.29Hodgkin's disease with a mediastinal mass greater than 10 cm: results of four different treatment approaches. ( Allen, PK; Besa, P; Cabanillas, F; Cox, JD; Hagemeister, FB; McLaughlin, P; Preti, A; Rodriguez, A; Swan, F, 1994)
"Between 1980 and 1988, 48 patients with Hodgkin's disease who had large mediastinal masses were treated at Stanford University."1.29Hodgkin's disease with bulky mediastinal involvement: effective management with combined modality therapy. ( Behar, RA; Hoppe, RT; Horning, SJ, 1993)
"Of 157 patients with Hodgkin's disease treated between 1970 and 1981 an assessment of the clinical course was possible in 134 cases."1.27[Recurrence in Hodgkin's disease: incidence, therapy and prognosis. (Experience with 134 patients)]. ( Denz, H; Huber, H; Lechleitner, M; Peer, L; Peschel, C, 1983)
"There was no significant difference in recurrence rates between patients without mediastinal mass and patients with a small mass, and in these patients adjuvant chemotherapy MOPP after radiotherapy showed an evident benefit in reducing the relapse rate."1.27Prognostic significance of large mediastinal involvement in Hodgkin's disease. ( Baccarani, M; Cantore, M; Dominici, G; Emiliani, E; Faedi, M; Fiacchini, M; Frezza, G; Lauria, F; Mazza, P; Sciascia, R, 1983)
"Of 244 patients with Hodgkin's disease, 126 (52%) had an abnormal mediastinum."1.27Observations on the treatment of mediastinal masses in Hodgkin's disease emphasizing site of failure. ( Chan, PY; Hintz, BL; Kagan, AR; McMahon, J; Nussbaum, H; Rao, AR; Ryoo, MC; Wollin, M, 1987)
"A case of recurrent Hodgkin's disease of the "sarcomatoid" or "syncytial variant" type was seen that occurred as an extension from the mediastinum to a previously uninvolved extranodal site (breast) and pericardium after treatment of classical nodular sclerosing Hodgkin's disease based in the lymph nodes."1.27Recurrent "syncytial variant" of Hodgkin's disease: an immunohistologic diagnosis. ( Blaustein, JC; Lewkow, L, 1987)
"94 patients with Hodgkin's disease PS I or II, treated during the period 1969-78 and followed until death, or from 33 to 136 months after initiation of therapy, were analysed."1.27Prognostic significance of tumour burden in Hodgkin's disease PS I and II. ( Nissen, NI; Specht, L, 1986)
"Thymic hyperplasia is a poorly understood, apparently benign process that may be confused with recurrent lymphoma."1.27Thymic hyperplasia masquerading as recurrent Hodgkin's disease: case report and review of the literature. ( Edington, H; Longo, DL; Pass, H; Roth, JA; Salwitz, J, 1986)
"A case of thymic Hodgkin's disease presenting with an anterior mediastinal mass is reported."1.27Cystic degeneration of thymic Hodgkin's disease following radiation therapy. ( Haas, A; Kim, HC; Lewis, R; Nosher, J; Sweeney, W, 1985)
"47 patients with advanced Hodgkin's disease (stage IIIB or IV) and mediastinal involvement, treated during the period 1969-78 and followed till death or from 36 to 126 months after initiation of therapy, were analysed."1.27Therapeutic implications of mediastinal involvement in advanced Hodgkin's disease. ( Nissen, NI; Specht, L; Walbom-Jørgensen, S, 1985)
"A 27 year old man with Hodgkin's disease experienced three separate episodes of chest pain, each occurring on the sixth day of a cycle of mustargen, oncovin, procarbazine, prednisone (MOPP) combination chermotherapy."1.26Unusual cardiac reaction to chemotherapy following mediastinal irradiation in a patient with Hodgkin's disease. ( Greenwald, ES; Grossman, J; Weinstein, P, 1976)

Research

Studies (47)

TimeframeStudies, this research(%)All Research%
pre-199030 (63.83)18.7374
1990's10 (21.28)18.2507
2000's4 (8.51)29.6817
2010's2 (4.26)24.3611
2020's1 (2.13)2.80

Authors

AuthorsStudies
Zawati, I1
Adouni, O1
Finetti, P1
Manai, M2
Gamoudi, A1
Birnbaum, D1
Bertucci, F1
Mezlini, A1
Advani, RH1
Hong, F1
Fisher, RI1
Bartlett, NL1
Robinson, KS1
Gascoyne, RD1
Wagner, H1
Stiff, PJ1
Cheson, BD1
Stewart, DA1
Gordon, LI1
Kahl, BS1
Friedberg, JW1
Blum, KA1
Habermann, TM1
Tuscano, JM1
Hoppe, RT4
Horning, SJ3
Dunleavy, K1
Grant, C1
Eberle, FC1
Pittaluga, S1
Jaffe, ES2
Wilson, WH2
REWCASTLE, NB1
SMITH, JC1
KARNOFSKY, DA1
GONDOS, B1
REINGOLD, IM1
MATTOSO, LF1
STONE, DL1
Zhen, ZJ1
Sun, XF1
Xia, Y1
Wang, ZH1
Ling, JY1
Aleman, BM1
Raemaekers, JM1
Tomiŝiĉ, R1
Baaijens, MH1
Bortolus, R1
Lybeert, ML1
van der Maazen, RW1
Girinsky, T1
Demeestere, G1
Lugtenburg, P1
Lievens, Y1
de Jong, D1
Pinna, A1
Henry-Amar, M1
Advani, R1
Maeda, L1
Lavori, P1
Quon, A1
Hoppe, R1
Breslin, S1
Rosenberg, SA2
Denz, H1
Lechleitner, M1
Peschel, C1
Peer, L1
Huber, H1
Mazza, P1
Lauria, F1
Sciascia, R1
Emiliani, E1
Fiacchini, M1
Baccarani, M1
Frezza, G1
Dominici, G1
Cantore, M1
Faedi, M1
Hagemeister, FB5
Fuller, LM5
Sullivan, JA1
North, L1
Velasquez, W1
Conrad, FG1
McLaughlin, P3
Butler, JJ2
Shullenberger, CC1
Kantor, G1
Cosset, JM1
Masselot, J1
Coleman, CN1
Cox, RS1
Kaplan, HS1
Mauch, P1
Hellman, S2
Brusamolino, E1
Lazzarino, M1
Orlandi, E1
Canevari, A1
Morra, E1
Castelli, G1
Alessandrino, EP1
Pagnucco, G1
Astori, C1
Livraghi, A1
Preti, A1
Swan, F1
Rodriguez, A1
Besa, P1
Cox, JD1
Allen, PK1
Cabanillas, F2
Behar, RA1
Vecchi, V1
Pileri, S1
Burnelli, R1
Bontempi, N1
Comelli, A1
Testi, AM1
Carli, M1
Sotti, G1
Rosati, D1
Di Tullio, MT1
Gosselin, M1
Podgorsak, EB1
Evans, MD1
Pla, M1
Shenouda, G1
Grigoraki, V1
Lilienthal, F1
Touboul, E1
Gabarre, J1
Binet, JL1
Merle-Béral, H1
Salloum, E1
Tallini, G1
Levy, A1
Cooper, DL1
Longo, DL2
Glatstein, E1
Duffey, PL1
Young, RC1
Ihde, DC1
Bastian, AW1
Wittes, RE1
Hubbard, SM1
DeVita, VT1
Elconin, JH1
Roberts, KB1
Rizzieri, DA1
Vermont, C1
Clough, RW1
Kim, C1
Dodge, RK1
Prosnitz, LR1
Madoc-Jones, H1
Gamble, JF1
Sullivan, MP1
Fernandez, CH1
Gehan, EA1
Weinstein, P1
Greenwald, ES1
Grossman, J1
Ganesan, TS1
Oza, A1
Perry, N1
D'Ardenne, J1
Arnott, S1
Stansfeld, AG1
Shand, WS1
Wrigley, PF1
Lister, TA1
Djulbegovic, B1
Hendler, FJ1
Hamm, J1
Hadley, T1
Woodcock, TM1
Ferrant, A1
Hamoir, V1
Binon, J1
Michaux, JL1
Sokal, G1
North, LB2
Sullivan-Halley, JA1
Velasquez, WS1
Willett, CG1
Linggood, RM1
Leong, JC1
Miketic, LM1
Stracher, MA1
Skates, SJ1
Kushner, DC1
Ryoo, MC1
Kagan, AR1
Wollin, M1
Nussbaum, H1
Chan, PY1
Hintz, BL1
Rao, AR1
McMahon, J1
Blaustein, JC1
Lewkow, L1
Specht, L2
Nissen, NI2
Edington, H1
Salwitz, J1
Roth, JA1
Pass, H1
Kim, HC1
Nosher, J1
Haas, A1
Sweeney, W1
Lewis, R1
Walbom-Jørgensen, S1
Leslie, NT1
Mauch, PM1
Górecki, R1
Zajgner, J1
Wawrzeńczyk, B1
Lokich, JJ1
Levitt, SH1
Jones, TK1
Kilpatrick, SJ1
Bogardus, CR1
Bruneau, R1
Rubin, P1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Randomized Phase III Trial of ABVD Versus Stanford V (+/-) Radiation Therapy in Locally Extensive and Advanced Stage Hodgkin's Disease[NCT00003389]Phase 3854 participants (Actual)Interventional1999-06-17Completed
Phase III Randomized Trial of Adjuvant Involved-Field Radiotherapy vs No Adjuvant Therapy Following Remission Induction With MOPP/ABV Hybrid Chemotherapy in Patients With Stage III/IV Hodgkin's Disease[NCT00002462]Phase 3615 participants (Actual)Interventional1989-09-30Active, not recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

5-year Overall Survival

Overall survival is defined as the time from randomization to death or last known alive. The 5-year survival rate is the probability a patient survives 5 years. (NCT00003389)
Timeframe: Assessed every 2 months if patient is < 1 year from study entry, every 3 months for the second year, every 4 months for the third year, every 6 months for years 4 and 5, and yearly for 5 years

InterventionProportion of patients (Number)
Arm A (ABVD)0.88
Arm B (Stanford V)0.88

Failure-free Survival at 5 Years

"Failure-free survival is defined as the time from randomization to the earlier of progression/relapse or death. The 5-year failure-free survival is the probability a patient is failure-free and survives 5 years.~Progression is defined as an increase in size of 25% of the sum of the products of the pretreatment measurements or appearance of new lesions. Significant enlargement of the liver or spleen is evidence of progression. A significant increase in size is defined as > 2.0 cm in distance between costal margin and the inferior margin of either organ.~Relapse is defined as the re-appearance of any clinical evidence of Hodgkin's disease in a patient who has had a complete response. Relapse for partial responders is defined as progressive disease relative to disease status during the partial remission." (NCT00003389)
Timeframe: Assessed every 2 months if patient is < 1 year from study entry, every 3 months for the second year, every 4 months for the third year, every 6 months for years 4 and 5

InterventionProportion of patients (Number)
Arm A (ABVD)0.74
Arm B (Stanford V)0.71

Incidence of Second Cancers

Number of patients who developed second primary cancers (NCT00003389)
Timeframe: Assessed every 2 months if patient is < 1 year from study entry, every 3 months for the second year, every 4 months for the third year, every 6 months for years 4 and 5, and yearly for 5 years

Interventionparticipants (Number)
Arm A (ABVD)15
Arm B (Stanford V)19

Reviews

3 reviews available for mechlorethamine and Mediastinal Neoplasms

ArticleYear
Gray zone lymphoma: better treated like hodgkin lymphoma or mediastinal large B-cell lymphoma?
    Current hematologic malignancy reports, 2012, Volume: 7, Issue:3

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Dacarbazine; Doxorubicin; Hodgkin Disease

2012
Modality treatment in adult stage I-II Hodgkin's disease with large mediastinal masses: study of 30 cases and review of the literature.
    Nouvelle revue francaise d'hematologie, 1993, Volume: 35, Issue:4

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Female

1993
Burkitt's lymphoma-leukemia in patients treated for Hodgkin's disease.
    Cancer investigation, 1996, Volume: 14, Issue:6

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Burkitt Lymphoma; Cyclophosphamide

1996

Trials

8 trials available for mechlorethamine and Mediastinal Neoplasms

ArticleYear
Randomized Phase III Trial Comparing ABVD Plus Radiotherapy With the Stanford V Regimen in Patients With Stages I or II Locally Extensive, Bulky Mediastinal Hodgkin Lymphoma: A Subset Analysis of the North American Intergroup E2496 Trial.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2015, Jun-10, Volume: 33, Issue:17

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Chemotherapy, Adjuvant

2015
Involved-field radiotherapy for patients in partial remission after chemotherapy for advanced Hodgkin's lymphoma.
    International journal of radiation oncology, biology, physics, 2007, Jan-01, Volume: 67, Issue:1

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Combined Modalit

2007
Treatment of stage I and II mediastinal Hodgkin disease. A comparison of involved fields, extended fields, and involved fields followed by MOPP in patients staged by laparotomy.
    Radiology, 1981, Volume: 141, Issue:3

    Topics: Antineoplastic Combined Chemotherapy Protocols; Drug Therapy, Combination; Female; Hodgkin Disease;

1981
Treatment of pediatric Hodgkin disease tailored to stage, mediastinal mass, and age. An Italian (AIEOP) multicenter study on 215 patients.
    Cancer, 1993, Sep-15, Volume: 72, Issue:6

    Topics: Adolescent; Age Factors; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Child; Child, Pr

1993
Alternating MOPP and ABVD chemotherapy plus mantle-field radiation therapy in patients with massive mediastinal Hodgkin's disease.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1997, Volume: 15, Issue:11

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Child; Combined Modali

1997
New assessment of the prognostic significance of histopathology in Hodgkin's disease for laparotomy-negative stage I and stage II patients.
    Cancer, 1977, Volume: 39, Issue:5

    Topics: Adolescent; Adult; Clinical Trials as Topic; Drug Therapy, Combination; Female; Hodgkin Disease; Hum

1977
The adjuvant role of two cycles of MOPP and low-dose lung irradiation in stage IA through IIB Hodgkin's disease: preliminary results.
    International journal of radiation oncology, biology, physics, 1988, Volume: 14, Issue:4

    Topics: Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; Follow-Up Studies; Hodgkin

1988
Treatment of malignant superior vena caval obstruction. A randomized study.
    Cancer, 1969, Volume: 24, Issue:3

    Topics: Adenocarcinoma; Blood Pressure; Carcinoma; Carcinoma, Squamous Cell; Diuretics; Humans; Lymphoma; Ly

1969

Other Studies

36 other studies available for mechlorethamine and Mediastinal Neoplasms

ArticleYear
Adolescents and young adults with classical Hodgkin lymphoma in northern Tunisia: insights from an adult single-institutional study.
    Cancer radiotherapie : journal de la Societe francaise de radiotherapie oncologique, 2020, Volume: 24, Issue:3

    Topics: Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protoc

2020
SUBACUTE CEREBELLAR DEGENERATION WITH HODGKIN'S DISEASE.
    Archives of neurology, 1963, Volume: 9

    Topics: Ataxia; Cerebellar Diseases; Hodgkin Disease; Humans; Mechlorethamine; Mediastinal Neoplasms; Nerve

1963
RADIATION PNEUMONITIS. CASE REPORT OF BILATERAL REACTION AFTER UNILATERNAL IRRADIATION.
    The American review of respiratory disease, 1964, Volume: 89

    Topics: Child; Lymphatic Metastasis; Lymphoma; Lymphoma, Non-Hodgkin; Mechlorethamine; Mediastinal Neoplasms

1964
NONSURGICAL TREATMENT OF PULMONARY CANCER.
    Modern treatment, 1964, Volume: 1

    Topics: Adenocarcinoma, Bronchiolo-Alveolar; Adrenal Cortex Hormones; Alkylating Agents; Antineoplastic Agen

1964
MEDIASTINAL GANGLIONEUROBLASTOMA METASTASIZING TO SCALENE LYMPH NODES IN AN ADULT. REPORT OF A CASE AND REVIEW OF THE LITERATURE.
    The Journal of thoracic and cardiovascular surgery, 1964, Volume: 47

    Topics: Autopsy; Black People; Brain Neoplasms; Carcinoma; Carcinoma, Bronchogenic; Diagnosis, Differential;

1964
LOW BACK PAIN: AN UNUSUAL CAUSE OF A COMMON COMPLAINT.
    JAMA, 1965, Jun-21, Volume: 192

    Topics: Back Pain; Drug Therapy; Hodgkin Disease; Humans; Low Back Pain; Lumbosacral Region; Mechlorethamine

1965
[Clinical analysis of reactive thymic hyperplasia following chemotherapy for childhood malignant lymphoma].
    Ai zheng = Aizheng = Chinese journal of cancer, 2006, Volume: 25, Issue:4

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Child; Child, Preschool; Daca

2006
Impact of positive positron emission tomography on prediction of freedom from progression after Stanford V chemotherapy in Hodgkin's disease.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2007, Sep-01, Volume: 25, Issue:25

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Disease Progression; Doxorubicin;

2007
[Recurrence in Hodgkin's disease: incidence, therapy and prognosis. (Experience with 134 patients)].
    Wiener klinische Wochenschrift, 1983, May-13, Volume: 95, Issue:10

    Topics: Antineoplastic Combined Chemotherapy Protocols; Hodgkin Disease; Humans; Mechlorethamine; Mediastina

1983
Prognostic significance of large mediastinal involvement in Hodgkin's disease.
    Scandinavian journal of haematology, 1983, Volume: 31, Issue:4

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Female

1983
[Advantages of thoracic CT scanning in the treatment of mediastinal lymphomas].
    Bulletin du cancer, 1982, Volume: 69, Issue:3

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Humans; Lymphoma; Mechlorethamine

1982
The management of stage I--II Hodgkin's disease with irradiation alone or combined modality therapy: the Stanford experience.
    Blood, 1982, Volume: 59, Issue:3

    Topics: Adult; Aged; Drug Therapy, Combination; Female; Follow-Up Studies; Hodgkin Disease; Humans; Lymph No

1982
Supradiaphragmatic Hodgkin's disease: is there a role for MOPP chemotherapy in patients with bulky mediastinal disease?
    International journal of radiation oncology, biology, physics, 1980, Volume: 6, Issue:7

    Topics: Drug Therapy, Combination; Hodgkin Disease; Humans; Mechlorethamine; Mediastinal Neoplasms; Predniso

1980
Early-stage Hodgkin's disease: long-term results with radiotherapy alone or combined radiotherapy and chemotherapy.
    Annals of oncology : official journal of the European Society for Medical Oncology, 1994, Volume: 5 Suppl 2

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cause of Death; Combin

1994
Hodgkin's disease with a mediastinal mass greater than 10 cm: results of four different treatment approaches.
    Annals of oncology : official journal of the European Society for Medical Oncology, 1994, Volume: 5 Suppl 2

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Combined Modality Ther

1994
Hodgkin's disease with bulky mediastinal involvement: effective management with combined modality therapy.
    International journal of radiation oncology, biology, physics, 1993, Apr-02, Volume: 25, Issue:5

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Combined Modalit

1993
A technique using parallel-opposed high energy electron beams for reirradiation of tumors near the spinal cord.
    International journal of radiation oncology, biology, physics, 1993, Dec-01, Volume: 27, Issue:5

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Female; Hodgkin Disease; Humans; Mechloretham

1993
Radiation dose selection in Hodgkin's disease patients with large mediastinal adenopathy treated with combined modality therapy.
    International journal of radiation oncology, biology, physics, 2000, Nov-01, Volume: 48, Issue:4

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Bleomyci

2000
Unusual cardiac reaction to chemotherapy following mediastinal irradiation in a patient with Hodgkin's disease.
    The American journal of medicine, 1976, Volume: 60, Issue:1

    Topics: Adult; Drug Therapy, Combination; Heart; Hodgkin Disease; Humans; Male; Mechlorethamine; Mediastinal

1976
Management of stage II Hodgkin's disease: 15 years experience at St. Bartholomew's Hospital.
    Annals of oncology : official journal of the European Society for Medical Oncology, 1992, Volume: 3, Issue:5

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Combined Modalit

1992
Residual mediastinal mass after treatment of Hodgkin's disease: a decision analysis.
    Medical hypotheses, 1992, Volume: 38, Issue:2

    Topics: Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Decision Trees; Hodgkin D

1992
Combined modality therapy for mediastinal Hodgkin's disease. Prognostic significance of constitutional symptoms and size of disease.
    Cancer, 1985, Jan-15, Volume: 55, Issue:2

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carmustine; Comb

1985
Two cycles of MOPP and definitive radiotherapy for stage IIIA and IIIB Hodgkin's disease.
    Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer, 1989, Volume: 117

    Topics: Abdominal Neoplasms; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Fert

1989
Regression of mediastinal Hodgkin disease after therapy: evaluation of time interval.
    Radiology, 1987, Volume: 164, Issue:3

    Topics: Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Female; Follow-Up Studies

1987
Stage IA to IIB mediastinal Hodgkin's disease: three-dimensional volumetric assessment of response to treatment.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1988, Volume: 6, Issue:5

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Child; Dose-Response Relationship

1988
Observations on the treatment of mediastinal masses in Hodgkin's disease emphasizing site of failure.
    American journal of clinical oncology, 1987, Volume: 10, Issue:3

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Child; C

1987
Recurrent "syncytial variant" of Hodgkin's disease: an immunohistologic diagnosis.
    Human pathology, 1987, Volume: 18, Issue:7

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Female; Hodgkin Disease; Hu

1987
Prognostic significance of tumour burden in Hodgkin's disease PS I and II.
    Scandinavian journal of haematology, 1986, Volume: 36, Issue:4

    Topics: Antineoplastic Combined Chemotherapy Protocols; Hodgkin Disease; Humans; Mechlorethamine; Mediastina

1986
Thymic hyperplasia masquerading as recurrent Hodgkin's disease: case report and review of the literature.
    Journal of surgical oncology, 1986, Volume: 33, Issue:2

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Diagnosis, Differential; Hodgkin Disease

1986
Cystic degeneration of thymic Hodgkin's disease following radiation therapy.
    Cancer, 1985, Jan-15, Volume: 55, Issue:2

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Cysts; Diagnosis, Differential; Hodgkin Disea

1985
Therapeutic implications of mediastinal involvement in advanced Hodgkin's disease.
    Scandinavian journal of haematology, 1985, Volume: 35, Issue:2

    Topics: Antineoplastic Combined Chemotherapy Protocols; Follow-Up Studies; Hodgkin Disease; Humans; Mechlore

1985
Stage IA to IIB supradiaphragmatic Hodgkin's disease. Long-term survival and relapse frequency.
    Cancer, 1985, May-01, Volume: 55, Issue:9 Suppl

    Topics: Adolescent; Adult; Age Factors; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Presch

1985
The management of stage II Hodgkin's disease with a large mediastinal mass: a prospective program emphasizing irradiation.
    International journal of radiation oncology, biology, physics, 1985, Volume: 11, Issue:2

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Child; Combined Modality Therapy;

1985
Mechanisms of lymphorrhage into the serous cavities with description of a case.
    Polish medical journal, 1972, Volume: 11, Issue:5

    Topics: Adult; Anti-Bacterial Agents; Chylothorax; Chylous Ascites; Cyclophosphamide; Dexamethasone; Drainag

1972
The management of malignant pericardial effusions.
    JAMA, 1973, Jun-04, Volume: 224, Issue:10

    Topics: Angiography; Cardiac Tamponade; Fluorouracil; Gold; Heart Neoplasms; Humans; Lung; Mechlorethamine;

1973
The management of pleural effusions and chylothorax in lymphoma.
    Radiology, 1965, Volume: 85, Issue:6

    Topics: Adult; Chylothorax; Exudates and Transudates; Female; Humans; Leukemia, Lymphoid; Lymphoma, Large B-

1965