Page last updated: 2024-10-30

mechlorethamine and Lymphoma, Non-Hodgkin

mechlorethamine has been researched along with Lymphoma, Non-Hodgkin in 176 studies

nitrogen mustard : Compounds having two beta-haloalkyl groups bound to a nitrogen atom, as in (X-CH2-CH2)2NR.

Lymphoma, Non-Hodgkin: Any of a group of malignant tumors of lymphoid tissue that differ from HODGKIN DISEASE, being more heterogeneous with respect to malignant cell lineage, clinical course, prognosis, and therapy. The only common feature among these tumors is the absence of giant REED-STERNBERG CELLS, a characteristic of Hodgkin's disease.

Research Excerpts

ExcerptRelevanceReference
"To determine the long-term outcome of patients presenting with synchronous lymphoma and severe liver dysfunction and to describe the outcome of patients treated with initial mechlorethamine-based therapy used as a bridge to more conventional chemotherapy."3.72Therapeutic options in patients with lymphoma and severe liver dysfunction. ( Ansell, SM; Colgan, JP; Fonseca, R; Ghobrial, IM; Habermann, TM; Inwards, DJ; Markovic, SN; Micallef, IN; Pereira, DL; Porrata, LF; White, WL; Witzig, TE; Wolf, RC, 2004)
"Fourteen had Hodgkin's and four non-Hodgkin's lymphoma."2.68Prevention of irreversible chemotherapy-induced ovarian damage in young women with lymphoma by a gonadotrophin-releasing hormone agonist in parallel to chemotherapy. ( Avivi, I; Ben-Shahar, M; Blumenfeld, Z; Epelbaum, R; Haim, N; Linn, S, 1996)
"The response rate and survival in diffuse histiocytic lymphoma have improved since the first study."2.64Chemotherapy of non-Hodgkin's lymphoma: 10 years' experience in the Southwest Oncology Group. ( Coltman, CA; Jones, SE; Luce, JK; McKelvey, EM; Moon, TE, 1977)
"Malignant lymphoma is classified into the following five major categories: aggressive lymphoma, indolent B-lymphoma, Hodgkin's disease, T-lymphoblastic lymphoma and adult T-cell leukemia-lymphoma (ATL)."2.39[Recent progress in the chemotherapy of malignant lymphoma]. ( Tobinai, K, 1995)
"Chemotherapy of malignant lymphomas has accomplished a significant progress during the two decades."2.38[Current status of chemotherapy in the treatment of malignant lymphomas]. ( Hayashi, K; Kimura, I; Mizuta, J; Murashima, M; Ohnoshi, T; Tada, A; Tagawa, S; Ueno, K, 1989)
"Seventy-five Hodgkin lymphoma and non-Hodgkin lymphoma patients and a control group of 257 fertile men."1.40Impact of lymphoma treatments on spermatogenesis and sperm deoxyribonucleic acid: a multicenter prospective study from the CECOS network. ( Auger, J; Berthaut, I; Brugnon, F; Bujan, L; Daudin, M; Hennebicq, S; Moinard, N; Rives, N; Saias, J; Szerman, E; Walschaerts, M, 2014)
"Of the 13 cases, 5 were Hodgkin's disease (HD), and 8 were non-Hodgkin's lymphoma (NHL)."1.33[Clinical analysis of reactive thymic hyperplasia following chemotherapy for childhood malignant lymphoma]. ( Ling, JY; Sun, XF; Wang, ZH; Xia, Y; Zhen, ZJ, 2006)
"We followed-up 33 patients with non-Hodgkin's lymphoma or with Hodgkin's disease during the years 1987-1997 who were referred for semen cryopreservation."1.31Follow-up of sperm concentration and motility in patients with lymphoma. ( Botchan, A; Hauser, R; Paz, G; Tal, R; Yavetz, H; Yogev, L, 2000)
"Patients treated for Hodgkin's disease and non-Hodgkin lymphomas were followed for 5 years after start of therapy."1.30Five-year follow-up of saliva in patients treated for lymphomas. ( Keinànen, S; Laine, P; Lindqvist, C; Meurman, JH; Pyrhönen, S; Teerenhovi, L, 1997)
"The occurrence of HIV associated non-Hodgkin's lymphoma (NHL) is a well recognized event."1.29Hodgkin's disease and non-Hodgkin's lymphoma in an HIV positive patient. ( Brody, J; Goh, JC; Kaplan, MH; Koduru, P; Lichtman, SM; Susin, M, 1993)
"More than 50% of patients with non Hodgkin's lymphomas (NHL) are long-term survivors."1.29[Semen preservation and gonadal toxicity in the treatment of non Hodgkin lymphoma. Experience at the Gustave-Roussy Institute from 1980 to 1993]. ( Auger, J; Bendahmane, B; Decaudin, D; Koscielny, S; Munck, JN; Naccache, P, 1996)
"The frequency of chromosome aberrations in the peripheral blood of patients successfully treated for Hodgkin's disease (HD) and non-Hodgkin's lymphoma is compared with that seen in age-matched haematologically normal subjects."1.28Chromosome aberrations following cytotoxic therapy in patients in complete remission from lymphoma. ( Clark, RE; Jacobs, A; Jones, BM; White, AD, 1992)
"Patients with diffuse histiocytic lymphoma who achieved a histologically proven complete remission after 6 months of treatment without maintenance have remained disease-free whereas those with nodular poorly differentiated lymphocytic and diffuse well-differentiated lymphocytic lymphomas have demonstrated a pattern of continuous late recurrence."1.25Non-Hodgkin's lymphoma: patterns of relapse from complete remission after combination chemotherapy. ( Canellos, GP; Chabner, BA; DeVita, VT; Schein, PS; Young, RC, 1975)

Research

Studies (176)

TimeframeStudies, this research(%)All Research%
pre-1990126 (71.59)18.7374
1990's33 (18.75)18.2507
2000's12 (6.82)29.6817
2010's3 (1.70)24.3611
2020's2 (1.14)2.80

Authors

AuthorsStudies
Zimmerman, K1
Walsh, KA1
Ferrari, JT1
Keuler, NS1
Atherton, MJ1
Lenz, JA1
Wehkamp, U1
Jost, M1
Gosmann, J1
Grote, U1
Bernard, M1
Stadler, R1
Bujan, L1
Walschaerts, M1
Brugnon, F1
Daudin, M1
Berthaut, I1
Auger, J2
Saias, J1
Szerman, E1
Moinard, N1
Rives, N1
Hennebicq, S1
HUNTER, OB1
EICHENLAUB, FJ1
OLIVO, MA1
WINTROBE, MM4
HUGULEY, CM2
SHERRY, M1
Cronin, PA1
Myers, E1
Redmond, HP1
O'Reilly, S1
Kirwan, WO1
GOODMAN, LS2
Fenn, JE1
Udelsman, R1
NARDI, FL1
KLIMA, R1
HORNISCHER, R1
SIEVERS, K1
HARWERTH, HG1
MEYER, OO1
KAWAMURA, H1
ITANO, T1
SKINNER, EF1
ISBELL, H1
CARR, D1
INTROZZI, P1
MARINONE, G1
BEATTIE, JW1
HOWELLS, LH1
HOCHMAN, A2
ICKOWICZ, M1
SOROKIN, NM1
EBERHARD, R1
GAJARDO, M1
RATH, CE1
THOMSON, TJ1
HAASE, S1
RATZKOWSKI, A1
SPAIN, DM1
DI PIETRO, S2
BERNARD, J3
MATHE, G2
WEIL, M3
LOVISETTO, P1
CASTELLANO, M1
LAMBERS, K1
JACKSON, K1
McGREW, E1
COLE, WH1
WINKLER, JW1
ROOSA, RA1
DELAMATER, ED1
KRASOVSKII, II1
IAKOVLEV, AM1
BELLELLI, L1
SPEAR, PW1
PATNO, ME1
WATSON, JI1
WILKINSON, RD1
CRAIG, GE1
MOLANDER, DW1
ZEZZANETO, L1
SOERENSEN, B1
SALIBA, AM1
GRECCHI, R1
SMITH, JC1
CREPALDI, G1
PARPAJOLA, A1
MURPHY, WT1
BILGE, N1
MCALISTER, WH1
MARGULIS, AR1
BURNINGHAM, RA1
RESTREPO, A1
PUGH, RP1
BROWN, EB1
SCHLOSSMAN, SF1
KHURI, PD1
LESSNER, HE1
HARRINGTON, WJ1
DIAMANDOPOULOS, GT1
SMITH, EB1
KRESS, MB1
HIRSCHFELD, JH1
TANIDA, T1
FUJIMORI, M1
SAKAUCHI, G1
IZUO, M1
ABE, C1
MORITA, S1
NASHIMOTO, T1
ISHIKAWA, S1
SADMITSU, H1
KAWAI, T1
PAPAC, RJ1
WOOD, DA2
IRIARTE, P1
JAGASIA, H1
THURMAN, WG1
KARNOFSKY, DA2
HUTCHISON, JL1
CLARKSON, B1
VANDERVELDE, SL1
HOVORKA, JJ1
BROCKHOUSE, JP1
ROBINSON, BE1
HOYNE, RM1
HALNAN, KE1
MORROW, LB1
ANDERSON, RE1
CLIFFORD, P1
BHARDWAJ, BV1
WHITTAKER, LR1
MELANDRI, F1
PATRONCINI, F1
PRADHAN, SN1
WEST, WL1
RABENKO, J2
CORREA URQUIZA, LM1
Ogawa, M1
Mandigers, CM1
Verdonck, LF1
Meijerink, JP1
Dekker, AW1
Schattenberg, AV1
Raemaekers, JM2
Hehn, ST1
Miller, TP2
MARTINEZ PENUELA, JM1
MASOUREDIS, SP1
LOW-BEER, BV1
BIERMAN, HR1
CHERNEY, LS1
SHIMKIN, MB1
BADER, DN1
LEVI, M1
MENE, G1
FERRI, A1
JOYEUX, R1
COURTY, A1
BERTRAND, L1
de LORENZO, J1
JANNINI, P1
BARENGHI, G1
ABOU SINNA, I1
BERTLICH, W1
HEITE, HJ1
GARCIA PEREZ, A1
QUINONES CARAVIA, PA1
KIELER, J1
Ghobrial, IM1
Wolf, RC1
Pereira, DL1
Fonseca, R1
White, WL1
Colgan, JP1
Habermann, TM1
Inwards, DJ1
Markovic, SN1
Ansell, SM1
Micallef, IN1
Porrata, LF1
Witzig, TE1
SAITA, G1
SWEITZER, SE1
CUMMING, HA1
McAFEE, GD1
CABY, F1
TSEVRENIS, H1
Wessels, G1
Bernard Hesseling, P1
Moser, EC1
Noordijk, EM3
Carde, P2
Tirelli, U3
Baars, JW1
Thomas, J3
Bron, D2
Meerwaldt, JH3
van Glabbeke, M2
Kluin-Nelemans, HC1
Zhen, ZJ1
Sun, XF1
Xia, Y1
Wang, ZH1
Ling, JY1
Bachmeyer, C1
Orlandini, V1
Aractingi, S1
BEN-ASHER, S1
MEYER, AH1
OVERMILLER, WC1
Shohat, B1
Gitter, S1
Lavie, D1
Klastersky, J1
Giustolisi, R1
Guglielmo, P1
Di Raimondo, F1
Milone, G1
Cacciola, E1
Jacquillat, C1
Khayat, D1
Desprez-Curely, JP1
Brocheriou, C1
Auclerc, G1
Chamseddine, N1
Dameshek, W2
Goodman, MJ1
Gilman, A1
McLennan, MT1
Coyne, J1
Dervan, P1
Portlock, CS1
Somers, R3
Keuning, JJ1
Delmer, A1
de Bock, R1
De Wolf-Peeters, C2
Keunig, JJ1
Sertoli, MR1
Santini, G2
Chisesi, T2
Congiu, AM1
Rubagotti, A1
Contu, A2
Salvagno, L2
Coser, P2
Porcellini, A2
Vespignani, M1
Longo, DL4
Duffey, PL2
Jaffe, ES3
Raffeld, M1
Hubbard, SM3
Fisher, RI6
Wittes, RE1
DeVita, VT8
Young, RC5
Tobinai, K2
Teodorovic, I2
Pittaluga, S2
Kluin-Nelemans, JC1
Hagenbeek, A2
Bijnens, L2
Peeters, CD1
Lichtman, SM1
Brody, J1
Kaplan, MH1
Susin, M1
Koduru, P1
Goh, JC1
Anderson, JR1
Vose, J1
Kessinger, A1
Jurcic, JG1
Koll, B1
Brown, AE1
Crown, JP1
Yahalom, J1
Gulati, SC1
Baxter, JD1
DiNubile, MJ1
Nagourney, RA1
Evans, SS1
Messenger, JC1
Su, YZ1
Weisenthal, LM1
Bokemeyer, C1
Schmoll, HJ1
van Rhee, J1
Kuczyk, M1
Schuppert, F1
Poliwoda, H1
Kaźmierczak, M1
Komarnicki, M1
Kroll, R1
Haim, N3
Leviov, M1
Ben-Arieh, Y1
Epelbaum, R2
Freidin, N1
Reshef, R1
Ben-Shahar, M3
Naccache, P1
Decaudin, D1
Koscielny, S1
Bendahmane, B1
Munck, JN1
Gaynor, ER2
Blumenfeld, Z2
Avivi, I1
Linn, S1
Meurman, JH2
Laine, P2
Keinànen, S1
Pyrhönen, S2
Teerenhovi, L2
Lindqvist, C2
Kamieńska, E1
Corti, C1
Theodore, C1
Bayle, C1
Rougier, P1
Nasr, F1
Cosset, JM1
Girinsky, T1
Hayat, M1
Ribrag, V1
Ritter, M1
Shen-Orr, Z1
Shariki, K1
Bairey, O1
Gabbay, U1
Blickstein, D1
Stark, P1
Prokocimer, M1
Epstein, O1
Shaklai, M1
Lahav, J1
Kuraishi, Y1
Usui, N1
Dobashi, N1
Poloni, A1
Leoni, P1
Curzi, L1
Cantori, I1
Mancini, S1
Montanari, M1
Masia, MC1
Olivieri, A1
Dubey, SP1
Sengupta, SK1
Kaleh, LK1
Morewaya, JT1
Dana, BW1
LeBlanc, M1
Kjeldsberg, C1
Forman, JD1
Unger, JM1
Balcerzak, SP1
Roy, V1
Miller, T1
Tal, R1
Botchan, A1
Hauser, R1
Yogev, L1
Paz, G1
Yavetz, H1
Cabanillas, F1
Avilés, A2
Neri, N1
Johnson, LP1
Rivkin, SE1
Weber, EL1
Bonadonna, G1
De Lena, M1
Lattuada, A1
Milani, F1
Monfardini, S1
Beretta, G1
Anderson, T1
Bender, RA1
Chabner, BA2
Berard, CW1
Norton, L1
Coltman, CA1
Luce, JK2
McKelvey, EM1
Jones, SE1
Moon, TE1
Goldberg, J1
Davey, FR1
Gottlieb, AJ1
Klein, HO1
Bar-Meir, S1
Pinkhas, J1
Golan, A1
Vries, A1
Kaufman, JH1
Ezdinli, E1
Aungst, CW1
Stutzman, L2
Schein, PS1
Canellos, GP2
Tenovuo, J1
Murtomaa, H1
Dodwell, DJ1
de Campos, ES1
Radford, JA1
White, AD1
Jones, BM1
Clark, RE1
Jacobs, A1
Wesley, MN1
Ihde, DC2
Gilliom, M1
Cossman, J1
Díaz-Maqueo, JC1
Talavera, A1
Guzmán, R1
García, EL1
Capnist, G1
Rizzoli, V1
Sertoli, M1
Rancan, L1
Gisselbrecht, C2
Lepage, E2
Sebban, C1
Coiffier, B1
Cunningham, D1
Hepplestone, A1
Gilchrist, NL1
Dagg, JH1
Evans, IL1
Soukop, M1
Sagher, D1
Karrison, T1
Schwartz, JL1
Larson, R1
Meier, P1
Strauss, B1
Brice, P1
Trédaniel, J1
Gerota, I1
Glatstein, E1
Zagonel, V1
Volpe, R1
Trovò, MG1
Carbone, A1
Ohnoshi, T1
Hayashi, K1
Ueno, K1
Tada, A1
Murashima, M1
Mizuta, J1
Tagawa, S1
Kimura, I1
Brown, T1
Dawson, AA1
Bennett, B1
Moore, NR1
España, P1
Bonilla, F1
Yebra, M1
Diego, J1
Alvarez de Mon, M1
Marazuela, M1
Durántez, A1
Anderson, CB1
Philpott, GW1
Ferguson, TB1
Knock, FE1
Galt, RM1
Oester, YT1
Sylvester, R1
Keipert, JA1
Roughon, C1
Levacher, JP1
Vaugier, G1
Van Thiel, DH1
Sherins, RJ2
Myers, GH1
De Vita, VT1
Reilly, CJ1
Han, T1
Slack, NH1
Webster, J1
Le Bourgeois, JP1
Delobel, J1
Wiltshaw, E1
Millett, Y1
Solomon, J1
Jacobs, EM2
Bateman, JR1
Lukes, RJ1
Weiner, JM1
Donohue, DM1
Carbone, PP1
Rubin, P2
Arseneau, JC1
Frei, E1
Peters, FC1
Zippin, C1
Lowenbraun, S1
Serpick, AA1
Gamble, JF1
Fuller, LM1
Butler, JJ1
Shullenberger, CC1
Muller, SA1
Schulze, TW1
Lewinski, U1
Garrett, MJ1
Glazebrook, GA1
el-Akkad, SM1
Shakir, MA1
DeConti, RC1
Kaplan, SR1
Calabresi, P1
Bruneau, R1
Lenhard, RE1
Owens, AH1
Perez, CA1
Olson, J1
Lewis, FB1
Schwartz, RS1

Clinical Trials (4)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Pilot Study of Idiotype Vaccine and EPOCH-Rituximab Chemotherapy in Untreated Mantle Cell Lymphoma[NCT00005780]Phase 226 participants (Actual)Interventional2000-06-01Completed
Ovarian Tissue Freezing For Fertility Preservation In Women Facing A Fertility Threatening Medical Diagnosis Or Treatment Regimen: A Study By The National Physicians Cooperative of the Oncofertility Consortium At Northwestern University[NCT00902720]Phase 425 participants (Anticipated)Interventional2009-05-31Recruiting
Maternal Cancer Diagnosis and Treatment During Pregnancy:a Registry for Maternal, Fetal, and Neonatal Outcomes With Longitudinal Follow up of Child Development and Maternal Psychological Well Being[NCT02749474]400 participants (Anticipated)Observational [Patient Registry]2003-07-31Recruiting
A Phase II Trial of Combined Weekly Bortezomib and Tositumomab I-131 in Patients With Relapsed or Refractory Follicular Non-Hodg[NCT00479167]Phase 21 participants (Actual)Interventional2007-05-31Terminated (stopped due to Lack of accrual and interest in study)
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Here is the Number of Participants With Serious and/or Non-serious Adverse Events Assessed by the Common Toxicity Criteria (CTC v2.0).

Here is the number of participants with serious and/or non-serious adverse events assessed by the Common Toxicity Criteria (CTC v2.0). A non-serious adverse event is any untoward medical occurrence. A serious adverse event is an adverse event or suspected adverse reaction that results in death, a life-threatening adverse drug experience, hospitalization, disruption of the ability to conduct normal life functions, congenital anomaly/birth defect or important medical events that jeopardize the patient or subject and may require medical or surgical intervention to prevent one of the previous outcomes mentioned. (NCT00005780)
Timeframe: Up to 30 days after last intervention, up to 12.5 months or 1.04 years

InterventionParticipants (Count of Participants)
Etoposide, Prednisone, Vincristine, Cyclophosphamide, Doxorubicin, and Rituximab26

Median Progression-free Survival (PFS) in Participants Treated With Etoposide, Prednisone, Vincristine, Cyclophosphamide, Doxorubicin, and Rituximab (EPOCH-R)

PFS is time from on study date until disease relapse or progression, death, or date of last follow-up. Progression was measured by the International Workshop to Standardize Response Criteria for non-Hodgkin's Lymphoma and is defined as ≥50% increase from nadir in the sum of the products of the greatest diameters (SPD) of any previously involved node or the appearance of any new lesion. (NCT00005780)
Timeframe: From participants on study date until date of disease relapse or progression, death, or date of last follow-up, assessed up to 245.8 months

InterventionMonths (Median)
Etoposide, Prednisone, Vincristine, Cyclophosphamide, Doxorubicin, and Rituximab23.5

Overall Survival (OS)

OS was determined by the Kaplan-Meier method and is defined as the time from treatment start date until date of death or last follow-up. (NCT00005780)
Timeframe: Time from treatment start date until date of death or date last follow-up, up to 250 months

InterventionMonths (Median)
Etoposide, Prednisone, Vincristine, Cyclophosphamide, Doxorubicin, and Rituximab89.7

Percentage of Participants With an Antibody Response to Idiotype Vaccine

Participants with an immune response to idiotype vaccine measured by enzyme-linked immunosorbent assay (ELISA) to detect antibody binding to tumor cells. Positive response was defined as at least a fourfold increase in antibody titer. (NCT00005780)
Timeframe: Weeks 12 to 32

Interventionpercentage of participants (Number)
Etoposide, Prednisone, Vincristine, Cyclophosphamide, Doxorubicin, and Rituximab30

Percentage of Participants With Antibodies to Keyhole Limpet Haemocyanin (KLH)

Participants with an immune response against carrier molecule KLH measured by enzyme-linked immunosorbent assay (ELISA) to detect antibody binding to tumor cells. Positive response was defined as at least a fourfold increase in antibody titer. (NCT00005780)
Timeframe: After vaccinations administered at 0, 1, 2, 3 and 5 months

Interventionpercentage of participants (Number)
Etoposide, Prednisone, Vincristine, Cyclophosphamide, Doxorubicin, and Rituximab74

Progression Free Survival (PFS) in Participants Who Received Idiotype Vaccine

PFS is defined as the time from start of treatment until disease relapse or progression, death, or last follow-up. Progression was measured by the International Workshop to Standardize Response Criteria for non-Hodgkin's Lymphoma and is defined as ≥50% increase from nadir in the sum of the products of the greatest diameters (SPD) of any previously involved node or the appearance of any new lesion (NCT00005780)
Timeframe: Time from treatment start date until date of disease relapse or progression, death, or date last follow-up, an average of 25 months

InterventionMonths (Median)
Etoposide, Prednisone, Vincristine, Cyclophosphamide, Doxorubicin, and Rituximab25.0

Time to Recovery of CD4 T Lymphocytes (CD4+)

Recovery of CD4+ was measured by flow cytometry. Blood samples were collected via apheresis and analyzed by multicolor flow cytometry in peripheral blood mononuclear cells (PBMCs) for cluster of differentiation 4 (CD4). Time to recovery of CD4 T lymphocytes was defined as the time required for CD4 T lymphocytes to increase above the lower limit of normal of the normal laboratory value range of 359 cells/mcL (NCT00005780)
Timeframe: After chemotherapy before vaccination, up to 6 months

InterventionMonths (Median)
Etoposide, Prednisone, Vincristine, Cyclophosphamide, Doxorubicin, and Rituximab3

Percentage of Participants Whose Cancer Shrinks or Disappears After Treatment With Etoposide, Prednisone, Vincristine, Cyclophosphamide, Doxorubicin, and Rituximab (EPOCH-R)

Response was measured by the International Workshop to Standardize Response Criteria for non-Hodgkin's Lymphoma. Complete Response (CR) is a complete disappearance of all detectable clinical and radiographic evidence of disease and disappearance of all disease-related symptoms if present before therapy, and normalization of those biochemical abnormalities (e.g., Lactate dehydrogenase (LDH) definitely assignable to the lymphoma. Complete Response Unconfirmed (CRu) is as per CR criteria except that if a residual node is > 1.5cm, it must have regressed by > 75% in the sum of the products of the greatest diameters (SPD). Partial Response (PR) is ≥50% decreased in the SPD of 6 largest dominant nodes or nodal masses. Stable Disease (SD) is defined as less than a PR but not progressive disease. Progression is ≥50% increase from nadir in the SPD of any previously involved node or the appearance of any new lesion. (NCT00005780)
Timeframe: After 6 cycles of EPOCH-R therapy, an average of 18 weeks

Interventionpercentage of participants (Number)
Complete ResponseComplete Response UnconfirmedPartial ResponseStable DiseaseProgression
Etoposide, Prednisone, Vincristine, Cyclophosphamide, Doxorubicin, and Rituximab80.87.77.703.8

Percentage of Participants With Grade 3 or Higher Serious and/or Non-serious Toxicity That Occurred That is at Least Possibly Related to Drug or Vaccine

Serious and/or non-serious adverse events were assessed by the Common Toxicity Criteria (CTC v2.0). A non-serious adverse event is any untoward medical occurrence. A serious adverse event is an adverse event or suspected adverse reaction that results in death, a life-threatening adverse drug experience, hospitalization, disruption of the ability to conduct normal life functions, congenital anomaly/birth defect or important medical events that jeopardize the patient or subject and may require medical or surgical intervention to prevent one of the previous outcomes mentioned. Grade 3 is severe, Grade 4 is life-threatening, and Grade 5 is death related to adverse event. (NCT00005780)
Timeframe: Up to 30 days after last intervention, up to 12.5 months or 1.04 years

,,
Interventionpercentage of participants (Number)
Allergic reactionAnemiaFebrile neutropeniaLeukopeniaLymphopeniaNeutropeniaThrombocytopeniaThrombosisInfusion related reactionSerum glutamic oxaloacetic transaminase (SGOT) elevationSerum glutamic pyruvic transaminase (SGPT) elevationInfectionHyperglycemiaHypomagnesemiaCerebrovascular ischemiaMotor neuropathySensory neuropathyBack painDyspneaErectile dysfunction
Grade 33.869.242.3038.505015.43.83.83.815.43.83.8011.53.83.83.83.8
Grade 403.83.884.6088.57.700003.8003.800000
Grade 500000000000000000000

Percentage of Participants With Induction of Type 1 Cytokine T-cell Response

Participants with tumor specific T-cell responses during B-cell recovery was assessed in a Clinical Laboratory Improvement Amendments (CLIA) certified lab and were measured by flow cytometry and/or enzyme-linked immunosorbent spot (ELISPOT). A positive response required the response to be at least twice the negative controls. (NCT00005780)
Timeframe: After vaccinations administered at 0, 1, 2, 3 and 5 months

Interventionpercentage of participants (Number)
Peripheral blood mononuclear cells (PBMC)Granulocyte macrophage colony-stimulating factor (GM-CSF)Tumor necrosis factor α (TNFα)Interferon-gamma (IFN-γ)
Etoposide, Prednisone, Vincristine, Cyclophosphamide, Doxorubicin, and Rituximab87655274

Reviews

15 reviews available for mechlorethamine and Lymphoma, Non-Hodgkin

ArticleYear
Lipomatosis: an unusual side-effect of cytotoxic chemotherapy?
    Acta dermato-venereologica, 2010, Volume: 90, Issue:3

    Topics: Antineoplastic Combined Chemotherapy Protocols; Humans; Lipomatosis; Lymphoma, Non-Hodgkin; Male; Me

2010
[Hematologic tumors].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2003, Volume: 30, Issue:10

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cyclophosphamide; Cytarabine; Dacarbazine

2003
What is the treatment of choice for advanced-stage Hodgkin's lymphoma: ABVD, Stanford V, or BEACOPP?
    Current hematology reports, 2004, Volume: 3, Issue:1

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Combined Modality Therapy; Cyclophosphami

2004
Perspectives of the management of childhood lymphoma: experience at Tygerberg Hospital, Western Cape, South Africa.
    Transfusion and apheresis science : official journal of the World Apheresis Association : official journal of the European Society for Haemapheresis, 2005, Volume: 32, Issue:1

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Blood Transfusion; Child; Combined

2005
Non-Hodgkin's lymphoma occurring after Hodgkin's disease. Four new cases and a review of the literature.
    Cancer, 1984, Feb-01, Volume: 53, Issue:3

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy;

1984
[High dose chemotherapy followed by hematopoietic stem cell transplantation for malignant lymphoma].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1995, Volume: 22, Issue:12

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cisplatin; Combined Modality Therapy; Cyt

1995
[Recent progress in the chemotherapy of malignant lymphoma].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1995, Volume: 22, Issue:4

    Topics: Antineoplastic Combined Chemotherapy Protocols; Clinical Trials, Phase III as Topic; Cyclophosphamid

1995
Clinical analysis of 670 cases in two trials of the European Organization for the Research and Treatment of Cancer Lymphoma Cooperative Group subtyped according to the Revised European-American Classification of Lymphoid Neoplasms: a comparison with the W
    Blood, 1996, May-15, Volume: 87, Issue:10

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Bone Marrow; Combined Modality Therapy; C

1996
Chemotherapy of intermediate-grade non-Hodgkin's lymphoma: is "more" or "less" better?
    Oncology (Williston Park, N.Y.), 1995, Volume: 9, Issue:12

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Clinical Trials, Phase II as Topic; Cyclo

1995
[Chemotherapy for non-Hodgkin's lymphoma].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1998, Volume: 25, Issue:14

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Combined Modality Therapy; Cyclophosphami

1998
Chemotherapy for Hodgkin's disease and aggressive non-Hodgkin's lymphoma. More is better, or is it?
    Drugs, 1992, Volume: 44, Issue:1

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Chemotherapy, Adjuvant;

1992
Long-term follow-up of ProMACE-CytaBOM in non-Hodgkin's lymphomas.
    Annals of oncology : official journal of the European Society for Medical Oncology, 1991, Volume: 2 Suppl 1

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cyclophosphamide; Cytarabine; Doxor

1991
[The place of bone marrow autografts in the treatment of Hodgkin's and non-Hodgkin's lymphoma].
    Nouvelle revue francaise d'hematologie, 1988, Volume: 30, Issue:1-2

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Bone Marrow Transplantation; Dacarbazine;

1988
[Current status of chemotherapy in the treatment of malignant lymphomas].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1989, Volume: 16, Issue:5

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy;

1989
Recently recognized complications of cancer chemotherapy.
    Annals of the New York Academy of Sciences, 1974, Volume: 230

    Topics: Antineoplastic Agents; Burkitt Lymphoma; Cyclophosphamide; Death, Sudden; Drug Therapy, Combination;

1974

Trials

21 trials available for mechlorethamine and Lymphoma, Non-Hodgkin

ArticleYear
Late non-neoplastic events in patients with aggressive non-Hodgkin's lymphoma in four randomized European Organisation for Research and Treatment of Cancer trials.
    Clinical lymphoma & myeloma, 2005, Volume: 6, Issue:2

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Europe; Female; Follow-Up S

2005
EORTC study of non-Hodgkin's lymphoma: phase III study comparing CHVmP-VB and ProMACE-MOPP in patients with stage II, III, and IV intermediate- and high-grade lymphoma.
    Annals of oncology : official journal of the European Society for Medical Oncology, 1994, Volume: 5 Suppl 2

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Combined Modality Therapy; C

1994
MACOP-B versus ProMACE-MOPP in the treatment of advanced diffuse non-Hodgkin's lymphoma: results of a prospective randomized trial by the non-Hodgkin's Lymphoma Cooperative Study Group.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1994, Volume: 12, Issue:7

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cyclophosphamide; Doxo

1994
Diffuse small noncleaved-cell, non-Burkitt's lymphoma in adults: a high-grade lymphoma responsive to ProMACE-based combination chemotherapy.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1994, Volume: 12, Issue:10

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Combined

1994
Efficacy of four different regimens in 64 mantle-cell lymphoma cases: clinicopathologic comparison with 498 other non-Hodgkin's lymphoma subtypes. European Organization for the Research and Treatment of Cancer Lymphoma Cooperative Group.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1995, Volume: 13, Issue:11

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Bleomyci

1995
Intermediate and high-grade gastric non-Hodgkin's lymphoma: a prospective study of non-surgical treatment with primary chemotherapy, with or without radiotherapy.
    Leukemia & lymphoma, 1995, Volume: 17, Issue:3-4

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Disease Progression;

1995
Clinical analysis of 670 cases in two trials of the European Organization for the Research and Treatment of Cancer Lymphoma Cooperative Group subtyped according to the Revised European-American Classification of Lymphoid Neoplasms: a comparison with the W
    Blood, 1996, May-15, Volume: 87, Issue:10

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Bone Marrow; Combined Modality Therapy; C

1996
Prevention of irreversible chemotherapy-induced ovarian damage in young women with lymphoma by a gonadotrophin-releasing hormone agonist in parallel to chemotherapy.
    Human reproduction (Oxford, England), 1996, Volume: 11, Issue:8

    Topics: Adolescent; Adult; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Antineoplastic Combined

1996
Inhibin A concentrations in the sera of young women during and after chemotherapy for lymphoma: correlation with ovarian toxicity.
    American journal of reproductive immunology (New York, N.Y. : 1989), 1998, Volume: 39, Issue:1

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Combined Modality Ther

1998
Interferon alpha consolidation after intensive chemotherapy does not prolong the progression-free survival of patients with low-grade non-Hodgkin's lymphoma: results of the Southwest Oncology Group randomized phase III study 8809.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2000, Volume: 18, Issue:10

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Disease Progression;

2000
Combination chemotherapy and radiotherapy in non-Hodgkin's lymphomata.
    The British journal of cancer. Supplement, 1975, Volume: 2

    Topics: Antineoplastic Agents; Bleomycin; Bone Marrow; Clinical Trials as Topic; Cyclophosphamide; Doxorubic

1975
Combination chemotherapy in non-Hodgkin's lymphoma: results of long-term followup.
    Cancer treatment reports, 1977, Volume: 61, Issue:6

    Topics: Adolescent; Adult; Aged; Bleomycin; Child; Clinical Trials as Topic; Cyclophosphamide; Doxorubicin;

1977
Chemotherapy of non-Hodgkin's lymphoma: 10 years' experience in the Southwest Oncology Group.
    Cancer treatment reports, 1977, Volume: 61, Issue:6

    Topics: Bleomycin; Clinical Trials as Topic; Cyclophosphamide; Cytarabine; Doxorubicin; Drug Administration

1977
Lymphosarcoma. A comparison of extended to conservative chemotherapy.
    Cancer, 1976, Volume: 37, Issue:3

    Topics: Adult; Aged; Carmustine; Chlorambucil; Cyclophosphamide; Drug Therapy, Combination; Female; Humans;

1976
Superiority of ProMACE-CytaBOM over ProMACE-MOPP in the treatment of advanced diffuse aggressive lymphoma: results of a prospective randomized trial.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1991, Volume: 9, Issue:1

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cyclophosphamide; Cytarabine; Doxor

1991
Long-term follow-up of ProMACE-CytaBOM in non-Hodgkin's lymphomas.
    Annals of oncology : official journal of the European Society for Medical Oncology, 1991, Volume: 2 Suppl 1

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cyclophosphamide; Cytarabine; Doxor

1991
ProMACE-MOPP vs MACOP-B in high grade non-Hodgkin's lymphomas: a randomised study in a multicenter cooperative study group (NHLCSG).
    Leukemia, 1991, Volume: 5 Suppl 1

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cyclophosphamide; Doxorubicin; Eto

1991
[Low-grade non-Hodgkin's lymphoma in the adult: new therapeutic approaches].
    Nouvelle revue francaise d'hematologie, 1987, Volume: 29, Issue:1

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Chlorambucil; Cyclophosphamide; Doxorubicin;

1987
The treatment of indolent lymphomas: watchful waiting v aggressive combined modality treatment.
    Seminars in hematology, 1988, Volume: 25, Issue:2 Suppl 2

    Topics: Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Cyclophosphamide; Doxorub

1988
Chemotherapy of lymphoma with mechlorethamine and vinblastine.
    Archives of internal medicine, 1973, Volume: 131, Issue:3

    Topics: Adult; Blood Cell Count; Blood Platelet Disorders; Clinical Trials as Topic; Evaluation Studies as T

1973
Mechlorethamine HCl and cyclophosphamide in the treatment of Hodgkin's disease and the lymphomas.
    JAMA, 1968, Feb-05, Volume: 203, Issue:6

    Topics: Chlorambucil; Clinical Trials as Topic; Cyclophosphamide; Dosage Forms; Follow-Up Studies; Hodgkin D

1968

Other Studies

142 other studies available for mechlorethamine and Lymphoma, Non-Hodgkin

ArticleYear
Evaluation of mechlorethamine, vinblastine, procarbazine, and prednisone for the treatment of resistant multicentric canine lymphoma.
    Veterinary and comparative oncology, 2023, Volume: 21, Issue:3

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Dog Diseases; Dogs; Doxorubicin; Lymphoma;

2023
Management of chlormethine gel treatment in mycosis fungoides patients in two German skin lymphoma centers.
    Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG, 2021, Volume: 19, Issue:7

    Topics: Humans; Lymphoma, Non-Hodgkin; Mechlorethamine; Mycosis Fungoides; Neoplasms, Connective Tissue; Ski

2021
Impact of lymphoma treatments on spermatogenesis and sperm deoxyribonucleic acid: a multicenter prospective study from the CECOS network.
    Fertility and sterility, 2014, Volume: 102, Issue:3

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Case-Control Studies; Combined Mod

2014
Unusual changes in lymphosarcoma under nitrogen mustard therapy.
    The American journal of pathology, 1948, Volume: 24, Issue:3

    Topics: Lymphoma; Lymphoma, Non-Hodgkin; Mechlorethamine

1948
Nitrogen mustard therapy of lymphosarcoma; report of a case.
    The Medical annals of the District of Columbia, 1948, Volume: 17, Issue:7

    Topics: Lymphoma; Lymphoma, Non-Hodgkin; Mechlorethamine; Mustard Compounds; Mustard Plant; Neoplasms; Nitro

1948
Nitrogen-mustard therapy for Hodgkin's disease, lymphosarcoma, the leukemias, and other disorders.
    Cancer, 1948, Volume: 1, Issue:3

    Topics: Hodgkin Disease; Leukemia; Lymphoma; Lymphoma, Non-Hodgkin; Mechlorethamine; Mustard Plant; Nitrogen

1948
Nitrogen mustards in the treatment of Hodgkin's disease and lymphosarcoma.
    Southern medical journal, 1948, Volume: 41, Issue:2

    Topics: Hodgkin Disease; Lymphoma; Lymphoma, Non-Hodgkin; Mechlorethamine; Nitrogen Mustard Compounds; Sarco

1948
Nitrogen mustard as a therapeutic agent for Hodgkin's disease, lymphosarcoma and leukemia.
    Annals of internal medicine, 1947, Volume: 27, Issue:4

    Topics: Hodgkin Disease; Humans; Leukemia; Lymphoma; Lymphoma, Non-Hodgkin; Mechlorethamine

1947
Nitrogen mustard therapy; use of methyl-bis (beta-chloroethyl) amine hydrochloride and tris (beta-chloroethyl) amine hydrochloride for Hodgkin's disease, lymphosarcoma, leukemia and certain allied and miscellaneous disorders.
    Journal of the American Medical Association, 1946, Sep-21, Volume: 132

    Topics: Amines; Gas Poisoning; Hodgkin Disease; Humans; Leukemia; Lymphoma; Lymphoma, Non-Hodgkin; Mechloret

1946
First use of intravenous chemotherapy cancer treatment: rectifying the record.
    Journal of the American College of Surgeons, 2011, Volume: 212, Issue:3

    Topics: Antineoplastic Agents; Head and Neck Neoplasms; History, 20th Century; Humans; Infusions, Intravenou

2011
[Nitrogen mustard therapy of various cases of malignant lymphogranuloma and lymphosarcoma].
    Accademia medica, 1952, Volume: 67, Issue:4

    Topics: Hodgkin Disease; Lymphoma; Lymphoma, Non-Hodgkin; Mechlorethamine; Nitrogen Mustard Compounds

1952
[Nitrogen mustard therapy of proliferative blood diseases; methods, experiences as well as application possibilities in therapy of carcinoma].
    Wiener medizinische Wochenschrift (1946), 1953, Jan-03, Volume: 103, Issue:1

    Topics: Hematologic Diseases; Hodgkin Disease; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid; Lymp

1953
[Treatment of symptomatic hemolytic anemias].
    Acta haematologica, 1953, Volume: 9, Issue:4

    Topics: Anemia, Hemolytic; Hodgkin Disease; Humans; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Non-Hodgkin;

1953
Treatment of Hodgkin's disease and the lymphosarcomas.
    Journal of the American Medical Association, 1954, Jan-09, Volume: 154, Issue:2

    Topics: Hodgkin Disease; Humans; Lymphoma; Lymphoma, Non-Hodgkin; Mechlorethamine; Nitrogen Mustard Compound

1954
[An autopsy case of reticulosarcomatosis treated with nitrogen mustard-N-oxide].
    Gan, 1953, Volume: 44, Issue:2-3

    Topics: Autopsy; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Non-Hodgkin; Mechlorethamine; Neoplasms; Nitroge

1953
Disseminated lymphoblastoma resembling pulmonary tuberculosis; temporary dramatic response to nitrogen mustard therapy; case report.
    Diseases of the chest, 1954, Volume: 25, Issue:5

    Topics: Humans; Lymphoma; Lymphoma, Non-Hodgkin; Mechlorethamine; Nitrogen Mustard Compounds; Tuberculosis,

1954
[Role of chemical cytostatic treatment in therapy of hemopathies producing chronic malignant conditions].
    Haematologica, 1953, Volume: 37, Issue:11

    Topics: Ethylamines; Hodgkin Disease; Humans; Leukemia; Lymphoma; Lymphoma, Large B-Cell, Diffuse; Lymphoma,

1953
Biological actions and therapeutic applications of nitrogen mustard.
    The Quarterly journal of medicine, 1954, Volume: 23, Issue:90

    Topics: Hodgkin Disease; Leukemia; Leukemia, Myeloid; Lymphoma; Lymphoma, Non-Hodgkin; Mechlorethamine; Nitr

1954
Treatment of the resistant stages of Hodgkin's disease and lymphoblastic diseases.
    The British journal of radiology, 1954, Volume: 27, Issue:320

    Topics: Cortisone; Hodgkin Disease; Lymphocytes; Lymphoma; Lymphoma, Non-Hodgkin; Mechlorethamine; Nitrogen

1954
[Therapeutic use of embichin].
    Klinicheskaia meditsina, 1954, Volume: 32, Issue:6

    Topics: Hodgkin Disease; Lymphoma, Non-Hodgkin; Mechlorethamine; Nitrogen Mustard Compounds

1954
[Lymphosarcoma in children].
    Revista chilena de pediatria, 1954, Volume: 25, Issue:8

    Topics: Child; Infant; Lymphoma; Lymphoma, Non-Hodgkin; Mechlorethamine; Nitrogen Mustard Compounds; Radioth

1954
the use of nitrogen mustard in the treatment of lymphoblastomas.
    Southern medical journal, 1955, Volume: 48, Issue:12

    Topics: Lymphoma; Lymphoma, Non-Hodgkin; Mechlorethamine; Nitrogen Mustard Compounds

1955
Reticulo-sarcoma of the stomach successfully treated with nitrogen mustard.
    The British journal of radiology, 1956, Volume: 29, Issue:338

    Topics: Animals; Humans; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Non-Hodgkin; Mechlorethamine; Neoplasms;

1956
[The resistant stage in lymphoblastomic diseases].
    Harefuah, 1955, Apr-15, Volume: 48, Issue:8

    Topics: Cortisone; Lymphoma; Lymphoma, Non-Hodgkin; Mechlorethamine; Nitrogen Mustard Compounds

1955
Rapid and extensive development of amyloidosis in association with nitrogen mustard therapy; report of a case.
    American journal of clinical pathology, 1956, Volume: 26, Issue:1

    Topics: Amyloidosis; Humans; Lymph Nodes; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Non-Hodgkin; Mechloreth

1956
[Clinical study of the antineoplastic effect of DL-p-bis(beta-chloroethyl) aminophenylalanine].
    Minerva medica, 1956, Aug-11, Volume: 47, Issue:63-64

    Topics: Animals; Antineoplastic Agents; Humans; Lymph Nodes; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Non-

1956
[Clinical study of the antineoplastic effect of DL-p-bis(beta-chloroethyl) aminophenylalanine].
    Minerva medica, 1956, Aug-11, Volume: 47, Issue:63-64

    Topics: Animals; Antineoplastic Agents; Humans; Lymph Nodes; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Non-

1956
[Clinical study of the antineoplastic effect of DL-p-bis(beta-chloroethyl) aminophenylalanine].
    Minerva medica, 1956, Aug-11, Volume: 47, Issue:63-64

    Topics: Animals; Antineoplastic Agents; Humans; Lymph Nodes; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Non-

1956
[Clinical study of the antineoplastic effect of DL-p-bis(beta-chloroethyl) aminophenylalanine].
    Minerva medica, 1956, Aug-11, Volume: 47, Issue:63-64

    Topics: Animals; Antineoplastic Agents; Humans; Lymph Nodes; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Non-

1956
[Trials of treatment by p-(di-2-chloroethylamino)phenylbutyric acid in Hodgkin's disease, chronic lymphoid leukemia and different sarcomas of lymphatic tissue; study of one hundred cases].
    Revue francaise d'etudes cliniques et biologiques, 1956, Volume: 1, Issue:10

    Topics: Hodgkin Disease; Leukemia; Leukemia, Lymphocytic, Chronic, B-Cell; Leukemia, Lymphoid; Lymphoid Tiss

1956
[Treatment of Hodgkin's disease, chronic lymphoid leukosis and various lymphosarcomas with p-(di-2-chloroethyl) aminophenylbutyric acid].
    Le Sang, 1957, Volume: 28, Issue:1

    Topics: Hodgkin Disease; Leukemia; Leukemia, Lymphoid; Lymphoma; Lymphoma, Non-Hodgkin; Mechlorethamine; Nit

1957
[P-bis-(beta-chloroethyl) aminophenylalanine (sarcolysin) in antiblastic chemotherapy with special reference to lymphatic blood diseases].
    Haematologica, 1958, Volume: 43, Issue:4

    Topics: Hodgkin Disease; Humans; Leukemia; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Non-Hodgkin; Mechloret

1958
[Treatment of lymphosarcoma].
    Arztliche Wochenschrift, 1958, Aug-01, Volume: 13, Issue:30-31

    Topics: Lymphoma; Lymphoma, Non-Hodgkin; Mechlorethamine; Nitrogen Mustard Compounds

1958
Prophylactic treatment of the Murphy Sturm rat lymphosarcoma with nitrogen mustard.
    Surgery, 1958, Volume: 44, Issue:6

    Topics: Lymphoma, Non-Hodgkin; Mechlorethamine; Neoplasms, Experimental; Nitrogen Mustard Compounds

1958
A CLINICAL study of the comparative effect of nitrogen mustard and DON in patients with bronchogenic carcinoma, Hodgkin's disease, lymphosarcoma, and melanoma.
    Journal of the National Cancer Institute, 1959, Volume: 22, Issue:2

    Topics: Antineoplastic Agents; Carcinoma, Bronchogenic; Hodgkin Disease; Humans; Leucine; Lymphoma; Lymphoma

1959
Hyperuricemia with uric acid nephropathy following nitrogen mustard therapy of lymphosarcoma; report of a case.
    The Medical annals of the District of Columbia, 1959, Volume: 28, Issue:2

    Topics: Hyperuricemia; Lymphoma; Lymphoma, Non-Hodgkin; Mechlorethamine; Nitrogen Mustard Compounds; Uric Ac

1959
A cytological evaluation of combined therapy in the 6C3HED lymphosarcoma. I. -SH-containing analogs in combination with nitrogen mustard and mapharsen.
    Cancer research, 1960, Volume: 20

    Topics: Antineoplastic Agents; Arsenicals; Humans; Lymphoma; Lymphoma, Non-Hodgkin; Mechlorethamine; Organic

1960
[A case of prolonged remission of lymphosarcomatosis after sarcolysin and roentgen-ray therapy].
    Voprosy onkologii, 1960, Volume: 6(11)

    Topics: Lymphoma, Non-Hodgkin; Mechlorethamine; Melphalan; Nitrogen Mustard Compounds

1960
The action of nitrogen mustards on the glycolysis and hexokinase activity of rat reticulo-sarcoma ascites cells.
    Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift fur Augenheilkunde, 1961, Volume: 14

    Topics: Animals; Ascites; Carbohydrate Metabolism; Carbohydrates; Glycolysis; Hexokinase; Lymphoma, Large B-

1961
A comparative study of the effectiveness of HN2 and cyclophosphamide in bronchogenic carcinoma, Hodgkin's disease and lymphosarcoma.
    Cancer chemotherapy reports, 1962, Volume: 16

    Topics: Antineoplastic Agents; Carcinoma, Bronchogenic; Cyclophosphamide; Hodgkin Disease; Lung Neoplasms; L

1962
Topical nitrogen mustard in cutaneous lymphosarcoma (mycosis fungoides).
    Canadian Medical Association journal, 1962, Dec-15, Volume: 87

    Topics: Humans; Lymphoma, Non-Hodgkin; Mechlorethamine; Musculoskeletal Diseases; Mycosis Fungoides; Skin Ne

1962
THE MALIGNANT LYMPHOMAS.
    The American journal of nursing, 1963, Volume: 63

    Topics: Adrenal Cortex Hormones; Chlorambucil; Cyclophosphamide; Hodgkin Disease; Humans; Lymphoma; Lymphoma

1963
[TEST OF THE ACTION OF SOME NITROGEN MUSTARD DERIVATIVES ON STICKER'S LYMPHOSARCOMA].
    Revista brasileira de cirurgia, 1963, Volume: 46

    Topics: Animals; Cyclophosphamide; Dogs; Lymphoma; Lymphoma, Non-Hodgkin; Mechlorethamine; Neoplasms; Neopla

1963
RADIATION PNEUMONITIS. CASE REPORT OF BILATERAL REACTION AFTER UNILATERNAL IRRADIATION.
    The American review of respiratory disease, 1964, Volume: 89

    Topics: Child; Lymphatic Metastasis; Lymphoma; Lymphoma, Non-Hodgkin; Mechlorethamine; Mediastinal Neoplasms

1964
EXCRETION OF TRYPTOPHAN METABOLITES IN DIFFERENT FORMS OF HAEMOBLASTOSIS.
    Clinica chimica acta; international journal of clinical chemistry, 1964, Volume: 9

    Topics: Cortisone; Cyclophosphamide; Genetic Diseases, X-Linked; Hodgkin Disease; Humans; Kynurenic Acid; Ky

1964
COMPRESSION OF THE SPINAL CORD IN PATIENTS WITH MALIGNANT LYMPHOMA.
    Radiology, 1964, Volume: 82

    Topics: Hodgkin Disease; Humans; Lymphoma; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Non-Hodgkin; Mechloret

1964
COMPARISON OF EFFECTS OF CHEMOTHERAPY AND LOCAL IRRADIATION ON THE VASCULARITY OF A TRANSPLANTED MOUSE LYMPHOSARCOMA; A STUDY USING ANGIOGRAPHY AND MICROANGIOGRAPHY.
    Radiology, 1964, Volume: 82

    Topics: Angiography; Animals; Blood Vessels; Lymphoma; Lymphoma, Non-Hodgkin; Mechlorethamine; Mice; Neoplas

1964
WEEKLY HIGH-DOSAGE GLUCOCORTICOSTEROID TREATMENT OF LYMPHOCYTIC LEUKEMIAS AND LYMPHOMAS.
    The New England journal of medicine, 1964, May-28, Volume: 270

    Topics: Anemia; Anemia, Hemolytic; Betamethasone; Chlorambucil; Dexamethasone; Geriatrics; Humans; Leukemia;

1964
PHAGOCYTOSIS IN RETICULUM CELL SARCOMA.
    Cancer, 1964, Volume: 17

    Topics: Adolescent; Black People; Child; Chlorambucil; Cyclophosphamide; Dactinomycin; Geriatrics; Leukemia;

1964
PRIMARY RETICULUM CELL SARCOMA OF THE LUNG WITH ENDOBRONCHIAL INVOLVEMENT. CASE REPORT.
    Diseases of the chest, 1964, Volume: 45

    Topics: Biopsy; Bronchial Neoplasms; Bronchoscopy; Cytodiagnosis; Humans; Lung Neoplasms; Lymphoma, Large B-

1964
[HISTOPATHOLOGICAL EFFECTS OF ANTINEOPLASTIC AGENTS ON MALIGNANT LYMPHOMA].
    Nagasaki Igakkai zasshi = Nagasaki medical journal, 1964, Volume: 39

    Topics: Antineoplastic Agents; Child; Chlorambucil; Cyclophosphamide; Dactinomycin; Geriatrics; Hodgkin Dise

1964
STUDIES ON REGIONAL PERFUSION AND INTRA-ARTERIAL INFUSION FOR CANCER CHEMOTHERAPY.
    Surgery, 1964, Volume: 55

    Topics: Antineoplastic Agents; Breast Neoplasms; Celiac Artery; Chemotherapy, Cancer, Regional Perfusion; Co

1964
LONG TERM RESULTS ACHIEVED WITH THE USE OF ALKYLATING AGENTS IN MALIGNANT LYMPHOMA AND HODGKIN'S DISEASE.
    Acta - Unio Internationalis Contra Cancrum, 1964, Volume: 20

    Topics: Alkylating Agents; Chlorambucil; Cyclophosphamide; Hodgkin Disease; Humans; Lymphoma; Lymphoma, Larg

1964
LYMPHANGIOGRAPHY FOR MALIGNANT DISEASES IN CHILDREN.
    JAMA, 1964, May-11, Volume: 188

    Topics: Adolescent; Child; Hodgkin Disease; Humans; Infant; Leukemia; Leukemia, Myeloid; Lymph Nodes; Lympha

1964
NONSURGICAL TREATMENT OF PULMONARY CANCER.
    Modern treatment, 1964, Volume: 1

    Topics: Adenocarcinoma, Bronchiolo-Alveolar; Adrenal Cortex Hormones; Alkylating Agents; Antineoplastic Agen

1964
THE MANAGEMENT OF LEUKEMIA AND LYMPHOMA.
    Applied therapeutics, 1964, Volume: 6

    Topics: Adrenal Cortex Hormones; Busulfan; Chlorambucil; Cortisone; Cyclophosphamide; Hodgkin Disease; Human

1964
RELATIONSHIP BETWEEN CELL TYPE, GLUCOSE CONCENTRATION, AND RESPONSE TO TREATMENT IN NEOPLASTIC EFFUSIONS.
    Cancer, 1964, Volume: 17

    Topics: Adenocarcinoma, Bronchiolo-Alveolar; Adolescent; Alkylating Agents; Antimetabolites; Antineoplastic

1964
LYMPHOSARCOMA OF THE ILEUM. A CASE REPORT AND DISCUSSION.
    The Journal of the Kansas Medical Society, 1964, Volume: 65

    Topics: Ascites; Ileum; Intestinal Neoplasms; Lymph Nodes; Lymphoma, Non-Hodgkin; Mechlorethamine; Neoplasm

1964
LYMPHOSARCOMA PRODUCING MIKULICZ SYNDROME.
    IMJ. Illinois medical journal, 1964, Volume: 126

    Topics: Drug Therapy; Geriatrics; Humans; Lymphoma; Lymphoma, Non-Hodgkin; Mechlorethamine; Mikulicz' Diseas

1964
LONG-TERM RESULTS OF X-RAY TREATMENT IN MALIGNANT DISEASE OF THE LYMPHO-RETICULAR SYSTEM.
    Acta - Unio Internationalis Contra Cancrum, 1964, Volume: 20

    Topics: Classification; England; Hodgkin Disease; Humans; Lymphoma; Lymphoma, Follicular; Lymphoma, Non-Hodg

1964
ACTIVE TUBERCULOSIS IN LEUKEMIA. MALIGNANT LYMPHOMA AND MYELOFIBROSIS.
    Archives of pathology, 1965, Volume: 79

    Topics: Alkylating Agents; Aminopterin; Busulfan; Hodgkin Disease; Humans; Leukemia; Leukemia, Lymphoid; Leu

1965
INTENSIVE NITROGEN MUSTARD THERAPY WITH ABDOMINAL AORTIC OCCLUSION IN NASOPHARYNGEAL CARCINOMA.
    British journal of cancer, 1965, Volume: 19

    Topics: Adenocarcinoma; Antineoplastic Agents; Aorta; Aorta, Abdominal; Busulfan; Carcinoma; Carcinoma, Squa

1965
[Results of prolonged treatment with chloronaphthyne in a case of reticulum cell sarcoma; preliminary note].
    Gazzetta medica italiana, 1955, Volume: 114, Issue:4

    Topics: Abdomen; Abdominal Neoplasms; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Non-Hodgkin; Mechlorethamin

1955
Effect of chlorambucil on synthesis of protein and nucleic acids in tumor-bearing mice.
    Cancer research, 1960, Volume: 20

    Topics: Animals; Chlorambucil; Lymphoma, Non-Hodgkin; Mechlorethamine; Mice; Neoplasms; Nitrogen Mustard Com

1960
[The use of nitrogen mustard in the treatment of lymphatic diseases of a malignant type].
    Prensa medica argentina, 1959, Oct-09, Volume: 46

    Topics: Hodgkin Disease; Humans; Lymphoma; Lymphoma, Follicular; Lymphoma, Large B-Cell, Diffuse; Lymphoma,

1959
[Results obtained with the use of chlorambucil in the treatment of malignant lymphopathies].
    La Semana medica, 1961, Jul-31, Volume: 119

    Topics: Chlorambucil; Hodgkin Disease; Humans; Lymphoma; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Non-Hodg

1961
Graft-versus-lymphoma effect of donor lymphocyte infusion in indolent lymphomas relapsed after allogeneic stem cell transplantation.
    Bone marrow transplantation, 2003, Volume: 32, Issue:12

    Topics: Adult; Antibodies, Monoclonal; Antibodies, Monoclonal, Murine-Derived; Antineoplastic Combined Chemo

2003
Nitrogen mustards in the treatment of neoplastic disease.
    Advances in internal medicine, 1950, Volume: 4

    Topics: Hodgkin Disease; Leukemia; Lung Neoplasms; Lymphoma; Lymphoma, Non-Hodgkin; Mechlorethamine; Mycosis

1950
[Blood proteins and lymphosarcoma].
    Revista clinica espanola, 1950, May-31, Volume: 37, Issue:4

    Topics: Blood Proteins; Lymphoma, Non-Hodgkin; Mechlorethamine; Neoplasms; Nitrogen Mustard Compounds; Sarco

1950
The partition of radio-phosphorus (P32) in blood, urine and tumor tissue in patients with Hodgkin's disease and lymphosarcoma before and after treatment with nitrogen mustard [methyl bis (beta-chloroethyl) amine].
    Journal of the National Cancer Institute, 1950, Volume: 11, Issue:2

    Topics: Amines; Hodgkin Disease; Humans; Lymphoma; Lymphoma, Non-Hodgkin; Mechlorethamine; Neoplasms; Phosph

1950
Treatment of lymphosarcoma with nitrogen mustard.
    Journal of the American Veterinary Medical Association, 1951, Volume: 118, Issue:888

    Topics: Animals; Dogs; Lymphoma; Lymphoma, Non-Hodgkin; Mechlorethamine; Neoplasms; Nitrogen Mustard Compoun

1951
[Effect of methyl-bis (beta-chloroethyl)amine hydrochloride on Hodgkin's disease, lymphosarcoma, leukemia and neoplasms].
    Rivista di patologia e clinica, 1951, Volume: 6, Issue:1

    Topics: Amines; Hodgkin Disease; Humans; Leukemia; Lymphoma; Lymphoma, Non-Hodgkin; Mechlorethamine; Neoplas

1951
[Ileo-mesenteric lymphosarcomata; trial treatment with nitrogen mustard].
    La semaine des hopitaux : organe fonde par l'Association d'enseignement medical des hopitaux de Paris, 1951, Mar-30, Volume: 27, Issue:24

    Topics: Ileum; Lymphoma; Lymphoma, Non-Hodgkin; Mechlorethamine; Mesentery; Neoplasms; Nitrogen Mustard Comp

1951
[Nitrogen mustard in the treatment of Hodgkin's disease, lymphosarcoma, leukemia and related diseases].
    Arquivos de clinica, 1951, Volume: 12, Issue:3

    Topics: Hodgkin Disease; Leukemia; Lymphoma; Lymphoma, Non-Hodgkin; Mechlorethamine; Nitrogen Mustard Compou

1951
[Naphthyl-chloroethylamine therapy of Hodgkin's disease and allied forms].
    Accademia medica, 1950, Volume: 65, Issue:12

    Topics: Cystitis; Hodgkin Disease; Lymphogranuloma Venereum; Lymphoma, Non-Hodgkin; Mechlorethamine; Neoplas

1950
The principles of radiation therapy of lymphoblastoma.
    The Journal of the Egyptian Medical Association, 1951, Volume: 34, Issue:5

    Topics: Hodgkin Disease; Leukemia; Lymphoma, Non-Hodgkin; Mechlorethamine; Nitrogen Mustard Compounds; Sarco

1951
[On nitrogen mustard therapy of mycosis fungoides. II. Histologic studies].
    Dermatologische Wochenschrift, 1951, Volume: 123, Issue:21

    Topics: Lymphoma; Lymphoma, Non-Hodgkin; Mechlorethamine; Mycosis Fungoides; Nitrogen Mustard Compounds

1951
[Case of mycosis fungoides treated with nitrogen mustard].
    Actas dermo-sifiliograficas, 1951, Volume: 42, Issue:9

    Topics: Lymphoma; Lymphoma, Non-Hodgkin; Mechlorethamine; Mycosis Fungoides; Nitrogen Mustard Compounds

1951
Nitrogen mustard therapy in Hodgkin's disease, lympho-reticulosarcomatosis and lymphatic leukaemia.
    Acta radiologica, 1951, Volume: 36, Issue:6

    Topics: Hodgkin Disease; Leukemia; Leukemia, Lymphoid; Lymphoma; Lymphoma, Non-Hodgkin; Mechlorethamine; Nit

1951
[Case of mycosis fungoides].
    Actas dermo-sifiliograficas, 1951, Volume: 43, Issue:2

    Topics: Lymphoma; Lymphoma, Non-Hodgkin; Mechlorethamine; Mycosis Fungoides; Nitrogen Mustard Compounds

1951
Therapeutic options in patients with lymphoma and severe liver dysfunction.
    Mayo Clinic proceedings, 2004, Volume: 79, Issue:2

    Topics: Adrenal Cortex Hormones; Adult; Aged; Aged, 80 and over; Alkaline Phosphatase; Antibodies, Monoclona

2004
[A case of lymphosarcoma treated with nitrogen mustard].
    Minerva medica, 1949, Sep-08, Volume: 40, Issue:44 Pt 2

    Topics: Humans; Lymphoma, Non-Hodgkin; Mechlorethamine; Neoplasms; Nitrogen Mustard Compounds; Sarcoma

1949
Lymphosarcoma treated with nitrogen mustard; report of a case.
    Archives of dermatology and syphilology, 1950, Volume: 61, Issue:1

    Topics: Lymphoma; Lymphoma, Non-Hodgkin; Mechlorethamine; Neoplasms; Nitrogen Mustard Compounds; Sarcoma

1950
[Treatment of a lymphosarcoma of the neck by combination of nitrogen mustard, radiotherapy and surgery].
    La Presse medicale, 1950, Apr-15, Volume: 58, Issue:23

    Topics: Lymphoma; Lymphoma, Non-Hodgkin; Mechlorethamine; Neck; Neoplasms; Nitrogen Mustard Compounds; Radio

1950
[Clinical analysis of reactive thymic hyperplasia following chemotherapy for childhood malignant lymphoma].
    Ai zheng = Aizheng = Chinese journal of cancer, 2006, Volume: 25, Issue:4

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Child; Child, Preschool; Daca

2006
Topical mechlorethamine and clobetasol in multifocal primary cutaneous marginal zone-B cell lymphoma.
    The British journal of dermatology, 2006, Volume: 154, Issue:6

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Clobetasol; Humans; Lymphoma, B-Cell; Lymphom

2006
Nitrogen mustard therapy; the use of methyl bis (B chloroethyl) amine hydrochloride in Hodgkin's disease, leukemia, lymphosarcoma and cancer of the lung.
    The American journal of the medical sciences, 1949, Volume: 217, Issue:2

    Topics: Amines; Ethylamines; Hodgkin Disease; Humans; Leukemia; Lung Diseases; Lung Neoplasms; Lymphoma; Lym

1949
The use of nitrogen mustard in Hodgkin's disease and lymphosarcoma.
    Annals of internal medicine, 1949, Volume: 30, Issue:2

    Topics: Ethylamines; Hodgkin Disease; Lymphoma; Lymphoma, Non-Hodgkin; Mechlorethamine; Neoplasms; Sarcoma

1949
Action of elatericin A on human leukemic and normal lymphocytes.
    Journal of the National Cancer Institute, 1967, Volume: 38, Issue:1

    Topics: Aminopterin; Animals; Antineoplastic Agents; Azirines; Cathartics; Cell Nucleus; Chlorambucil; Cyclo

1967
[Lymphomas. Treatment of malignant lymphomas. Current observations and future prospects].
    Revue medicale de Bruxelles, 1982, Volume: 3, Issue:4

    Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cyclophosphamide;

1982
Combination chemotherapy ("MABOP") in advanced refractory lymphocytic lymphoma with unfavorable histology.
    Haematologica, 1982, Volume: 67, Issue:5

    Topics: Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Doxor

1982
Landmark article Sept. 21, 1946: Nitrogen mustard therapy. Use of methyl-bis(beta-chloroethyl)amine hydrochloride and tris(beta-chloroethyl)amine hydrochloride for Hodgkin's disease, lymphosarcoma, leukemia and certain allied and miscellaneous disorders.
    JAMA, 1984, May-04, Volume: 251, Issue:17

    Topics: History, 20th Century; Hodgkin Disease; Humans; Leukemia; Lymphoma, Non-Hodgkin; Mechlorethamine; Ne

1984
Composite lymphoma: a case report.
    Irish journal of medical science, 1984, Volume: 153, Issue:2

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Hodgkin Disease; Humans; Lymph Nodes; Lymphoma

1984
Deferral of initial therapy for advanced indolent lymphomas.
    Cancer treatment reports, 1982, Volume: 66, Issue:3

    Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Drug Therap

1982
Hodgkin's disease and non-Hodgkin's lymphoma in an HIV positive patient.
    Leukemia & lymphoma, 1993, Volume: 9, Issue:4-5

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Child; Cyclophosphamide; Dexametha

1993
Myelodysplastic syndrome after autologous transplant for lymphoma.
    Blood, 1994, Dec-01, Volume: 84, Issue:11

    Topics: Antineoplastic Combined Chemotherapy Protocols; Hematopoietic Stem Cell Transplantation; Hodgkin Dis

1994
Excretion of Ascaris lumbricoides during total body irradiation.
    Bone marrow transplantation, 1994, Volume: 13, Issue:4

    Topics: Adult; Animals; Antineoplastic Combined Chemotherapy Protocols; Ascariasis; Ascaris lumbricoides; Bo

1994
Relapsing chickenpox in a young man with non-Hodgkin's lymphoma.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 1994, Volume: 18, Issue:5

    Topics: Acyclovir; Adult; Antineoplastic Combined Chemotherapy Protocols; Chickenpox; Cyclophosphamide; Doxo

1994
2 chlorodeoxyadenosine activity and cross resistance patterns in primary cultures of human hematologic neoplasms.
    British journal of cancer, 1993, Volume: 67, Issue:1

    Topics: Cladribine; Cytarabine; Doxorubicin; Drug Resistance; Drug Screening Assays, Antitumor; Humans; Leuk

1993
Long-term gonadal toxicity after therapy for Hodgkin's and non-Hodgkin's lymphoma.
    Annals of hematology, 1994, Volume: 68, Issue:3

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Cyclop

1994
[Non-Hodgkin's lymphoma in a patient after many years of remission of Hodgkin's disease].
    Acta haematologica Polonica, 1995, Volume: 26, Issue:3

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Female; Hodgkin Disease; Humans; Lymphoma, No

1995
[Semen preservation and gonadal toxicity in the treatment of non Hodgkin lymphoma. Experience at the Gustave-Roussy Institute from 1980 to 1993].
    Bulletin du cancer, 1996, Volume: 83, Issue:4

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Combined Modality Ther

1996
Five-year follow-up of saliva in patients treated for lymphomas.
    Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics, 1997, Volume: 83, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Albumins; Amylases; Analysis of Variance; Antineoplastic Combined Ch

1997
[Treatment results and prognostic significance of selected clinical and laboratory features in children diagnosed with malignant lymphoma].
    Annales Academiae Medicae Stetinensis, 1996, Volume: 42

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Bleomycin; Child; Child, P

1996
High incidence of secondary myelodysplastic syndromes following PROMACE-MOPP and involved field radiotherapy for localized gastric non-Hodgkin's lymphomas.
    Hematological oncology, 1996, Volume: 14, Issue:4

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Cyclophosphamide; Doxorubi

1996
Levels of proteins C and S do not decline subsequent to first line chemotherapy in lymphoma patients.
    Hematological oncology, 1997, Volume: 15, Issue:3

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; alpha-2-Antiplasmin; Antineoplastic Combined Chemotherap

1997
Ex vivo pharmacological purging of leukapheresis collections with nitrogen mustard: amifostine pretreatment improves both early and late peripheral blood progenitor cell recovery.
    Experimental hematology, 1999, Volume: 27, Issue:10

    Topics: Amifostine; Animals; Bone Marrow Purging; Cell Survival; Cells, Cultured; Colony-Forming Units Assay

1999
Adult head and neck lymphomas in Papua New Guinea: a retrospective study of 70 cases.
    The Australian and New Zealand journal of surgery, 1999, Volume: 69, Issue:11

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Burkitt Lymphoma; Combined Modali

1999
Follow-up of sperm concentration and motility in patients with lymphoma.
    Human reproduction (Oxford, England), 2000, Volume: 15, Issue:9

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cryopreservation; Daca

2000
Interferon does not prolong progression-free survival after ProMACE-MOPP.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2000, Sep-15, Volume: 18, Issue:18

    Topics: Antineoplastic Combined Chemotherapy Protocols; Clinical Trials, Phase III as Topic; Cyclophosphamid

2000
Hematological malignancies and pregnancy: a final report of 84 children who received chemotherapy in utero.
    Clinical lymphoma, 2001, Volume: 2, Issue:3

    Topics: Acute Disease; Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Behavior; Bleomyci

2001
Palliation in malignant pleural effusion.
    The American surgeon, 1975, Volume: 41, Issue:9

    Topics: Adenocarcinoma; Adult; Aged; Breast Neoplasms; Drainage; Female; Hodgkin Disease; Humans; Lung Neopl

1975
Histiocytic lymphoma of B cell origin.
    Archives of internal medicine, 1977, Volume: 137, Issue:6

    Topics: B-Lymphocytes; Cell Membrane; Humans; Immunoglobulins; Lymphoma, Large B-Cell, Diffuse; Lymphoma, No

1977
[Combination chemotherapy and synchronization therapy in lymphogranulomatosis and non-Hodgkin's lymphomas].
    Hamatologie und Bluttransfusion, 1976, Volume: 18

    Topics: Antineoplastic Agents; Cyclophosphamide; Drug Therapy, Combination; Hodgkin Disease; Humans; Lymphom

1976
Malignant lymphoma presenting as unilateral exophtalmos and thyroid nodule (author's transl)
    Haematologica, 1975, Volume: 60, Issue:1

    Topics: Axilla; Exophthalmos; Heart Neoplasms; Humans; Lymphoma; Lymphoma, Non-Hodgkin; Male; Mechlorethamin

1975
Non-Hodgkin's lymphoma: patterns of relapse from complete remission after combination chemotherapy.
    Cancer, 1975, Volume: 35, Issue:2

    Topics: Antineoplastic Agents; Bone Marrow; Cyclophosphamide; Drug Therapy, Combination; Humans; Lymph Nodes

1975
Salivary flow and composition in lymphoma patients before, during and after treatment with cytostatic drugs.
    European journal of cancer. Part B, Oral oncology, 1992, Volume: 28B, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Analysis of Variance; Antineoplastic Combined Chemotherapy Protocols

1992
Chromosome aberrations following cytotoxic therapy in patients in complete remission from lymphoma.
    Carcinogenesis, 1992, Volume: 13, Issue:7

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Cells, Cultured; Chromosome Aberrations

1992
Growth and development of children of mothers treated with chemotherapy during pregnancy: current status of 43 children.
    American journal of hematology, 1991, Volume: 36, Issue:4

    Topics: Acute Disease; Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Behavior; Bleomyci

1991
Failure of conventional chemotherapy in aggressive lymphomas.
    Postgraduate medical journal, 1987, Volume: 63, Issue:735

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cyclophosphamide; Doxorubici

1987
Low O6-alkylguanine DNA alkyltransferase activity in the peripheral blood lymphocytes of patients with therapy-related acute nonlymphocytic leukemia.
    Cancer research, 1988, Jun-01, Volume: 48, Issue:11

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Dacarbazine; Doxorubicin; Hodgkin Disease

1988
Non-Hodgkin's lymphoma in the elderly: a retrospective evaluation of toxicity related to aggressive vs. conservative treatments.
    Tumori, 1988, Aug-31, Volume: 74, Issue:4

    Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cyclophosphamide

1988
The effects of four drug regimens on sister chromatid exchange frequency in patients with lymphomas.
    Cancer genetics and cytogenetics, 1988, Volume: 36, Issue:1

    Topics: Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; DNA Damage; Doxorubicin; Hodgkin D

1988
[Second tumors in patients treated for Hodgkin's disease].
    Revista clinica espanola, 1988, Volume: 182, Issue:6

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Combined Modali

1988
The treatment of malignant pleural effusions.
    Cancer, 1974, Volume: 33, Issue:4

    Topics: Adenocarcinoma; Adolescent; Adult; Aged; Breast Neoplasms; Carcinoma, Small Cell; Carcinoma, Squamou

1974
In vitro estimate of sensitivity of individual human tumors to antitumor agents.
    Oncology, 1974, Volume: 30, Issue:1

    Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Arsenicals; Benzoates; Breast Neoplasms; Carbon Radi

1974
Temporary resolution of geographic tongue with cytotoxic therapy.
    Australian paediatric journal, 1974, Volume: 10, Issue:4

    Topics: Child; Drug Therapy, Combination; Glossitis, Benign Migratory; Humans; Lymphoma, Non-Hodgkin; Male;

1974
[False facial cellulitis: hematosarcoma].
    Revue de stomatologie et de chirurgie maxillo-faciale, 1973, Volume: 74, Issue:2

    Topics: Cellulitis; Diagnosis, Differential; Drug Therapy, Combination; Facial Neoplasms; Humans; Hydrazines

1973
Evidence for a specific seminiferous tubular factor affecting follicle-stimulating hormone secretion in man.
    The Journal of clinical investigation, 1972, Volume: 51, Issue:4

    Topics: Adult; Biopsy; Cell Count; Clomiphene; Cyclophosphamide; Follicle Stimulating Hormone; Hodgkin Disea

1972
Reticulum cell sarcoma. A review of radiotherapeutic experience.
    Cancer, 1972, Volume: 29, Issue:5

    Topics: Adolescent; Adult; Aged; Chlorambucil; Female; Follow-Up Studies; Humans; Lymphoma, Non-Hodgkin; Mal

1972
[Chylous effusion during reticulosarcoma].
    La Nouvelle presse medicale, 1973, Jan-13, Volume: 2, Issue:2

    Topics: Abdominal Neoplasms; Chylothorax; Humans; Hydrazines; Inguinal Canal; Lumbosacral Region; Lymphatic

1973
The place of chemotherapy in Hodgkin's disease and allied disorders.
    Proceedings of the Royal Society of Medicine, 1972, Volume: 65, Issue:12

    Topics: Blood Cell Count; Hodgkin Disease; Humans; Laparotomy; Liver Function Tests; Lymphoma, Large B-Cell,

1972
Management of patients with non-Hodgkin's lymphoma.
    Archives of internal medicine, 1973, Volume: 131, Issue:3

    Topics: Antineoplastic Agents; Burkitt Lymphoma; Cyclophosphamide; Hodgkin Disease; Humans; Lymphography; Ly

1973
Updated Hodgkin's disease. C. Advanced disease and special problems. Comment: the non-Hodgkin's lymphomas.
    JAMA, 1973, Jan-08, Volume: 223, Issue:2

    Topics: Burkitt Lymphoma; Cyclophosphamide; Hodgkin Disease; Humans; Leukemia; Lymphoma; Lymphoma, Large B-C

1973
Status and perspectives in chemotherapy of Hodgkin's disease.
    Archives of internal medicine, 1973, Volume: 131, Issue:3

    Topics: Animals; Antineoplastic Agents; Benzoates; Breast Neoplasms; Burkitt Lymphoma; Cyclophosphamide; Cyt

1973
Combination chemotherapy with nitrogen mustard, vincristine, procarbazine, and prednisone in lymphosarcoma and reticulum cell sarcoma.
    Cancer, 1970, Volume: 25, Issue:5

    Topics: Adult; Aged; Antineoplastic Agents; Benzoates; Bone Marrow; Female; Follow-Up Studies; Humans; Leuko

1970
Combined chemotherapy and radiotherapy for advanced Hodgkin's disease and reticulum cell sarcoma: a preliminary report.
    Southern medical journal, 1971, Volume: 64, Issue:7

    Topics: Adolescent; Adult; Aged; Blood Cell Count; Cyclophosphamide; Female; Hodgkin Disease; Humans; Lympho

1971
Mucha-Habermann disease mistaken for reticulum cell sarcoma.
    Archives of dermatology, 1971, Volume: 103, Issue:4

    Topics: Aged; Arthritis, Rheumatoid; Biopsy; Diagnosis, Differential; Female; Humans; Hypothyroidism; Lympho

1971
[Prolonged remission of reticulum cell sarcoma].
    Harefuah, 1971, Feb-01, Volume: 80, Issue:3

    Topics: Cyclophosphamide; Follow-Up Studies; Humans; Lymphoma, Non-Hodgkin; Male; Mechlorethamine; Middle Ag

1971
Combination chemotherapy in malignant disease.
    Clinical radiology, 1971, Volume: 22, Issue:4

    Topics: Administration, Oral; Blood Cell Count; Breast Neoplasms; Bronchial Neoplasms; Child, Preschool; Fem

1971
Endotoxin stimulation in patients with lymphoma: correlation with the myelosuppressive effects of alkylating agents.
    Blood, 1972, Volume: 39, Issue:5

    Topics: Agranulocytosis; Alkylating Agents; Bone Marrow Cells; Bone Marrow Examination; Cyclophosphamide; En

1972
The management of pleural effusions and chylothorax in lymphoma.
    Radiology, 1965, Volume: 85, Issue:6

    Topics: Adult; Chylothorax; Exudates and Transudates; Female; Humans; Leukemia, Lymphoid; Lymphoma, Large B-

1965
Recent advances in chemotherapy of lymphoma.
    The Johns Hopkins medical journal, 1967, Volume: 121, Issue:2

    Topics: Alkylating Agents; Chlorambucil; Cyclophosphamide; Hodgkin Disease; Humans; Lymphoma; Lymphoma, Larg

1967
Preoperative irradiation and chemotherapy in the prevention of surgical failures: experimental observations on an animal tumor model.
    Annals of surgery, 1969, Volume: 169, Issue:4

    Topics: Animals; Antineoplastic Agents; Cyclophosphamide; Lymphoma, Non-Hodgkin; Mechlorethamine; Mice; Mode

1969
X-radiation and alkylating agents as possible "trigger" mechanisms in the autoimmune complications of malignant lymphophroliferative disease.
    Clinical and experimental immunology, 1966, Volume: 1, Issue:1

    Topics: Adult; Aged; Anemia, Hemolytic, Autoimmune; Chlorambucil; Humans; Leukemia, Lymphoid; Lymphoma, Non-

1966