mechlorethamine has been researched along with Lymphoma, AIDS-Related in 6 studies
nitrogen mustard : Compounds having two beta-haloalkyl groups bound to a nitrogen atom, as in (X-CH2-CH2)2NR.
Lymphoma, AIDS-Related: B-cell lymphoid tumors that occur in association with AIDS. Patients often present with an advanced stage of disease and highly malignant subtypes including BURKITT LYMPHOMA; IMMUNOBLASTIC LARGE-CELL LYMPHOMA; PRIMARY EFFUSION LYMPHOMA; and DIFFUSE, LARGE B-CELL, LYMPHOMA. The tumors are often disseminated in unusual extranodal sites and chromosomal abnormalities are frequently present. It is likely that polyclonal B-cell lymphoproliferation in AIDS is a complex result of EBV infection, HIV antigenic stimulation, and T-cell-dependent HIV activation.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The proportion of intravenous drug abusers (IVDA) in HIV-HD (38%) is higher than in French HIV-infected population as a whole (20." | 3.78 | Human immunodeficiency virus associated Hodgkin's disease: report of 45 cases from the French Registry of HIV-Associated Tumors. ( Andrieu, JM; Brice, P; Colonna, P; Gastaut, JA; Lévy, R; Raphaël, M; Taillan, B; Tourani, JM, 1995) |
| "Hodgkin lymphoma is considered a common type of non-AIDS defining tumor among patients infected with HIV, commonly presenting as a widespread disease and with different pathologic features compared with Hodgkin lymphoma in the general population." | 1.34 | Hodgkin lymphoma among patients infected with HIV in post-HAART era. ( Buccheri, V; Calore, EE; Chamone, DA; Pessoa, VP; Pracchia, LF; Tanaka, PY, 2007) |
| "The occurrence of HIV associated non-Hodgkin's lymphoma (NHL) is a well recognized event." | 1.29 | Hodgkin's disease and non-Hodgkin's lymphoma in an HIV positive patient. ( Brody, J; Goh, JC; Kaplan, MH; Koduru, P; Lichtman, SM; Susin, M, 1993) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (50.00) | 18.2507 |
| 2000's | 3 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Spina, M | 2 |
| Gabarre, J | 2 |
| Rossi, G | 1 |
| Fasan, M | 2 |
| Schiantarelli, C | 1 |
| Nigra, E | 1 |
| Mena, M | 1 |
| Antinori, A | 1 |
| Ammassari, A | 1 |
| Talamini, R | 1 |
| Vaccher, E | 3 |
| di Gennaro, G | 1 |
| Tirelli, U | 3 |
| Tanaka, PY | 1 |
| Pessoa, VP | 1 |
| Pracchia, LF | 1 |
| Buccheri, V | 1 |
| Chamone, DA | 1 |
| Calore, EE | 1 |
| Lévy, R | 1 |
| Colonna, P | 1 |
| Tourani, JM | 1 |
| Gastaut, JA | 1 |
| Brice, P | 1 |
| Raphaël, M | 1 |
| Taillan, B | 1 |
| Andrieu, JM | 1 |
| Errante, D | 1 |
| Dolcetti, R | 1 |
| Gloghini, A | 1 |
| Serraino, D | 1 |
| Franceschi, S | 1 |
| Boiocchi, M | 1 |
| Carbone, A | 1 |
| Lichtman, SM | 1 |
| Brody, J | 1 |
| Kaplan, MH | 1 |
| Susin, M | 1 |
| Koduru, P | 1 |
| Goh, JC | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| "Prospective Non Randomized Study With Chemotherapy in Patients With Hodgkin's Disease and HIV Infection: Stanford V Regimen For Low Risk Patients, EBVP Regimen For High Risk Patients"[NCT00003262] | Phase 2 | 30 participants (Anticipated) | Interventional | 1997-05-31 | Active, not recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for mechlorethamine and Lymphoma, AIDS-Related
| Article | Year |
|---|---|
Human immunodeficiency virus associated Hodgkin's disease: report of 45 cases from the French Registry of HIV-Associated Tumors.
Topics: Adult; AIDS-Related Opportunistic Infections; Antineoplastic Combined Chemotherapy Protocols; Bleomy | 1995 |
3 trials available for mechlorethamine and Lymphoma, AIDS-Related
| Article | Year |
|---|---|
Stanford V regimen and concomitant HAART in 59 patients with Hodgkin disease and HIV infection.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Antiretroviral Therapy, Highly Active; | 2002 |
Human immunodeficiency virus associated Hodgkin's disease: report of 45 cases from the French Registry of HIV-Associated Tumors.
Topics: Adult; AIDS-Related Opportunistic Infections; Antineoplastic Combined Chemotherapy Protocols; Bleomy | 1995 |
Stanford V regimen and concomitant highly active antiretroviral therapy is feasible and active in patients with Hodgkin's disease and HIV infection.
Topics: Adult; Anti-HIV Agents; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Doxorubicin; Etop | 2000 |
3 other studies available for mechlorethamine and Lymphoma, AIDS-Related
| Article | Year |
|---|---|
Hodgkin lymphoma among patients infected with HIV in post-HAART era.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Antiretroviral Therapy, Highly Active; Bleomy | 2007 |
Hodgkin's disease and human immunodeficiency virus infection: clinicopathologic and virologic features of 114 patients from the Italian Cooperative Group on AIDS and Tumors.
Topics: Acquired Immunodeficiency Syndrome; Adult; Antineoplastic Combined Chemotherapy Protocols; Base Sequ | 1995 |
Hodgkin's disease and non-Hodgkin's lymphoma in an HIV positive patient.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Child; Cyclophosphamide; Dexametha | 1993 |