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mechlorethamine and Lymph Node Metastasis

mechlorethamine has been researched along with Lymph Node Metastasis in 42 studies

nitrogen mustard : Compounds having two beta-haloalkyl groups bound to a nitrogen atom, as in (X-CH2-CH2)2NR.

Research Excerpts

ExcerptRelevanceReference
"Ten patients with advanced stage (TNM IIB-IVB) mycosis fungoides were treated with a combination chemotherapy program consisting of bleomycin and methotrexate weekly, doxorubicin every 3 weeks, and topical nitrogen mustard daily (BAM-M)."7.67Treatment of advanced stage mycosis fungoides with bleomycin, doxorubicin, and methotrexate with topical nitrogen mustard (BAM-M). ( Adelstein, DJ; Davis, BR; Hines, JD; Zakem, MH, 1986)
"Forty-two patients with intransit metastases of melanoma in a limb were treated by isolated regional perfusion chemotherapy using mechlorethamine (nitrogen mustard)."7.67Regional isolated limb perfusion of melanoma intransit metastases using mechlorethamine (nitrogen mustard). ( Fortner, JG; Gould-Rossbach, P; Guerra, J; Horowitz, G; Knapper, WH; Ray, C; Schnog, J; Shiu, MH; Yeh, S, 1986)
"Ten patients with advanced stage (TNM IIB-IVB) mycosis fungoides were treated with a combination chemotherapy program consisting of bleomycin and methotrexate weekly, doxorubicin every 3 weeks, and topical nitrogen mustard daily (BAM-M)."3.67Treatment of advanced stage mycosis fungoides with bleomycin, doxorubicin, and methotrexate with topical nitrogen mustard (BAM-M). ( Adelstein, DJ; Davis, BR; Hines, JD; Zakem, MH, 1986)
"Forty-two patients with intransit metastases of melanoma in a limb were treated by isolated regional perfusion chemotherapy using mechlorethamine (nitrogen mustard)."3.67Regional isolated limb perfusion of melanoma intransit metastases using mechlorethamine (nitrogen mustard). ( Fortner, JG; Gould-Rossbach, P; Guerra, J; Horowitz, G; Knapper, WH; Ray, C; Schnog, J; Shiu, MH; Yeh, S, 1986)
"Thirteen patients with advanced (Stage III) malignant melanoma have been treated with high-dose chemotherapy (nitrogen mustard or a combination of BCNU and melphalan) combined with autologous, nonfrozen, bone marrow transplantation."3.66Treatment of advanced malignant melanoma with high-dose chemotherapy and autologous bone marrow transplantation. Preliminary results--Phase I study. ( Dantas, ME; Glode, LM; Koeppler, H; Morton, N; Robinson, WA; Sutherland, J; Thomas, MR, 1982)
"A group of 220 patients with mycosis fungoides (MF) and other lymphomatous diseases was treated with sustained topical applications of dilute aqueous solutions of mechlorethamine hydrochloride for intervals ranging in excess of seven years."3.65Topical chemotherapy and immunotherapy of mycosis fungoides: intermediate-term results. ( Asbell, SO; Grekin, DA; Johnson, WC; Van Scott, EJ; Vonderheid, EC, 1977)
"The treatment strategies of Hodgkin's lymphoma (HL) are different according to clinical stage and risk factors, yet the optimal treatment strategy remains unclear."1.34[Treatment results of stage IA Hodgkin lymphoma: a report of 97 cases]. ( Hu, DS; Hu, S; Song, QB; Tan, WY; Wei, L; Zeng, FY; Zhou, LQ, 2007)
"Of 6 patients who developed recurrence, 3 (7."1.33[Comparison of preliminary results of involved-field with extended field radiotherapy combined with chemotherapy for early stage Hodgkin's disease]. ( Han, JZ; Jin, J; Li, YX; Liu, XF; Liu, YP; Song, YW; Wang, SL; Wang, WH; Yu, ZH; Zhou, LQ, 2006)
"Clinical features predictive of disease progression include initial lymphadenopathy (stage IIA) and lack of complete response to initial treatment."1.30Clinical characteristics and long-term outcome of patients with generalized patch and/or plaque (T2) mycosis fungoides. ( Chow, S; Hoppe, RT; Kim, YH; Varghese, A, 1999)
"Seventeen patients with advanced stage Hodgkin's disease who relapsed or failed to respond to multiple regimens of combination chemotherapy (mostly Mechlorethamine, Vincristine, Procarbarzine, Prednisone and Adriamycin, Bleomycin, Vinblastine, Dacarbazine) were treated with accelerated hyperfractionated total lymphoid irradiation (TLI) and high-dose chemotherapy followed by autologous bone marrow transplantation (AuBMT)."1.28Total lymphoid irradiation, high-dose chemotherapy and autologous bone marrow transplantation for chemotherapy-resistant Hodgkin's disease. ( Clarkson, B; Fuks, Z; Gulati, S; Shank, B; Yahalom, J, 1989)
"The rate of recurrence formation was found to be in a significant correlation with general symptoms, age, size of the largest cluster of involved lymph nodes, combination of drugs and type of consolidating therapy."1.27[Peculiarities of the recurrence of lymphogranulomatosis in children following combined chemotherapy]. ( Kharatishvili, ZV; Kolygin, BA, 1983)
"Most of the children with Hodgkin's disease diagnosed before or during puberty can be cured with chemotherapy alone, and thus will not suffer from the damaging late effects of radiotherapy."1.27Treatment of Hodgkin's disease in children with or without radiotherapy. ( Behrendt, H; Van Bunningen, BN; Van Leeuwen, EF, 1987)
"Nineteen patients with Hodgkin's disease who relapsed primarily in nodal sites after intensive combination chemotherapy were retreated with wide-field radiation therapy alone or with additional chemotherapy between January 1971 and December 1984."1.27Wide-field radiation therapy alone or with chemotherapy for Hodgkin's disease in relapse from combination chemotherapy. ( Mauch, P; Rosenthal, D; Skarin, A; Tarbell, N; Weinstein, H, 1987)

Research

Studies (42)

TimeframeStudies, this research(%)All Research%
pre-199036 (85.71)18.7374
1990's4 (9.52)18.2507
2000's2 (4.76)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
MONROE, JL1
GHEI, PN1
DHAWAN, IK1
DUFOUR, A1
ANDRE, P1
TOKUYAMA, H1
SMITH, JC1
GRISWOLD, JD1
SMITH, ME1
IRIARTE, P1
JAGASIA, H1
THURMAN, WG1
GONDOS, B1
REINGOLD, IM1
GOLDMAN, BS1
PEARSON, FG1
Wang, WH1
Li, YX1
Song, YW1
Jin, J1
Liu, YP1
Wang, SL1
Zhou, LQ2
Liu, XF1
Yu, ZH1
Han, JZ1
Tan, WY1
Hu, DS1
Zeng, FY1
Song, QB1
Hu, S1
Wei, L1
Gilbert, JM1
Wade, PM1
Smith, RE1
Johns, ME1
Kolygin, BA1
Kharatishvili, ZV1
Chisesi, T1
Ricciardi, O1
Dal Fior, S1
Cappellari, F1
Pozza, F1
Dini, E1
Thomas, MR1
Robinson, WA1
Glode, LM1
Dantas, ME1
Koeppler, H1
Morton, N1
Sutherland, J1
Krementz, ET1
Carter, RD1
Sutherland, CM1
Muchmore, JH1
Ryan, RF1
Creech, O1
Kim, YH1
Chow, S1
Varghese, A1
Hoppe, RT2
Shields, TW1
Yee, J1
Conn, JH1
Robinette, CD1
Desforges, JF1
Rutherford, CJ1
Görlich, M1
Heise, E1
Számel, I1
Kerpel-Fronius, S1
Tormey, DC1
Vonderheid, EC1
Van Scott, EJ1
Johnson, WC1
Grekin, DA1
Asbell, SO1
Straus, DJ1
Gaynor, JJ1
Myers, J1
Merke, DP1
Caravelli, J1
Chapman, D1
Yahalom, J2
Clarkson, BD1
Viviani, S1
Bonadonna, G1
Santoro, A1
Zanini, M1
Zucali, R1
Negretti, E1
Valagussa, P1
Zakem, MH1
Davis, BR1
Adelstein, DJ1
Hines, JD1
Behrendt, H1
Van Bunningen, BN1
Van Leeuwen, EF1
Gulati, S1
Shank, B1
Clarkson, B1
Fuks, Z1
Mauch, P1
Tarbell, N1
Skarin, A1
Rosenthal, D1
Weinstein, H1
Abel, EA1
Deneau, DG1
Price, NM1
Shiu, MH1
Knapper, WH1
Fortner, JG1
Yeh, S1
Horowitz, G1
Schnog, J1
Guerra, J1
Gould-Rossbach, P1
Ray, C1
Kithier, K1
Lusher, J1
Brought, J1
Poulik, MD1
Yonemoto, RH1
Barton, DR1
Byron, RL1
Riihimaki, DU1
Linder, GT1
Crook, JN1
Cohn, I1
Knock, FE1
Galt, RM1
Oester, YT1
Sylvester, R1
Roughon, C1
Levacher, JP1
Vaugier, G1
Górecki, R1
Zajgner, J1
Wawrzeńczyk, B1
Le Bourgeois, JP1
Delobel, J1
Astrakhan, VI1
Garin, AM1
Vvedenskaia, NA1
Bychkov, MB1
Smirnova, IN1
Lehman, JA1
Smith, GV1
Cross, FS1

Reviews

2 reviews available for mechlorethamine and Lymph Node Metastasis

ArticleYear
Response of esthesioneuroblastoma to chemotherapy. Report of five cases and review of the literature.
    Cancer, 1984, Mar-01, Volume: 53, Issue:5

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Child; Combined Modality Therapy;

1984
Combined chemotherapy and surgery in breast cancer: a review.
    Cancer, 1975, Volume: 36, Issue:3

    Topics: Breast Neoplasms; Cyclophosphamide; Female; Fluorouracil; Humans; Lymphatic Metastasis; Mechloretham

1975

Trials

3 trials available for mechlorethamine and Lymph Node Metastasis

ArticleYear
Adjuvant chemotherapy of large bowel cancer.
    Cancer treatment reviews, 1982, Volume: 9, Issue:3

    Topics: Antineoplastic Agents; Clinical Trials as Topic; Colonic Neoplasms; Drug Therapy, Combination; Floxu

1982
Prognostic factors among 185 adults with newly diagnosed advanced Hodgkin's disease treated with alternating potentially noncross-resistant chemotherapy and intermediate-dose radiation therapy.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1990, Volume: 8, Issue:7

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Dacarbazine; Doxorubicin; Female;

1990
Alternating versus hybrid MOPP-ABVD in Hodgkin's disease: the Milan experience.
    Annals of oncology : official journal of the European Society for Medical Oncology, 1991, Volume: 2 Suppl 2

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Combined Modality Therapy; Dacarba

1991

Other Studies

37 other studies available for mechlorethamine and Lymph Node Metastasis

ArticleYear
THE MORBIDITY AND EFFICACY OF TOPICAL NITROGEN MUSTARD AS A SURGICAL ADJUVANT: A CLINICAL STUDY.
    Bulletin - Geisinger Medical Center, 1963, Volume: 15

    Topics: Adjuvants, Immunologic; Adjuvants, Pharmaceutic; Breast Neoplasms; Chemotherapy, Cancer, Regional Pe

1963
SQUAMOUS CELL CARCINOMA IN A CASE OF LUPUS VULGARIS (LUPUS CARCINOMA).
    Journal of the Indian Medical Association, 1963, Sep-16, Volume: 41

    Topics: Carcinoma; Carcinoma, Squamous Cell; Facial Neoplasms; Humans; Lupus Vulgaris; Lymphatic Metastasis;

1963
[APROPOS OF THE TREATMENT OF TUMORS OF THE TESTICLE].
    Journal d'urologie et de nephrologie, 1963, Volume: 69

    Topics: Castration; Choriocarcinoma; Dactinomycin; Female; Humans; Lung Neoplasms; Lymphatic Metastasis; Mal

1963
[CHEMOTHERAPY AND THE SPREAD OF CANCER].
    Rinsho geka. Journal of clinical surgery, 1963, Volume: 18

    Topics: Blood Circulation; Liver Neoplasms; Lymphatic Metastasis; Massage; Mechlorethamine; Neoplasm Metasta

1963
RADIATION PNEUMONITIS. CASE REPORT OF BILATERAL REACTION AFTER UNILATERNAL IRRADIATION.
    The American review of respiratory disease, 1964, Volume: 89

    Topics: Child; Lymphatic Metastasis; Lymphoma; Lymphoma, Non-Hodgkin; Mechlorethamine; Mediastinal Neoplasms

1964
NEUROBLASTOMA IN INFANCY AND CHILDHOOD.
    The Medical annals of the District of Columbia, 1964, Volume: 33

    Topics: Adrenal Gland Neoplasms; Antineoplastic Agents; Bone Neoplasms; Child; Humans; Infant; Lymphatic Met

1964
RETINAL INVOLVEMENT IN ADULT CYTOMEGALIC INCLUSION DISEASE.
    Archives of ophthalmology (Chicago, Ill. : 1960), 1964, Volume: 72

    Topics: Adult; Choroid; Cryptococcosis; Cyclophosphamide; Cytomegalovirus Infections; Eye Manifestations; Ge

1964
LYMPHANGIOGRAPHY FOR MALIGNANT DISEASES IN CHILDREN.
    JAMA, 1964, May-11, Volume: 188

    Topics: Adolescent; Child; Hodgkin Disease; Humans; Infant; Leukemia; Leukemia, Myeloid; Lymph Nodes; Lympha

1964
MEDIASTINAL GANGLIONEUROBLASTOMA METASTASIZING TO SCALENE LYMPH NODES IN AN ADULT. REPORT OF A CASE AND REVIEW OF THE LITERATURE.
    The Journal of thoracic and cardiovascular surgery, 1964, Volume: 47

    Topics: Autopsy; Black People; Brain Neoplasms; Carcinoma; Carcinoma, Bronchogenic; Diagnosis, Differential;

1964
MALIGNANT PERICARDIAL EFFUSION. REVIEW OF HOSPITAL EXPERIENCE AND REPORT OF A CASE SUCCESSFULLY TREATED BY TALC POUDRAGE.
    Canadian journal of surgery. Journal canadien de chirurgie, 1965, Volume: 8

    Topics: Breast Neoplasms; Cardiac Surgical Procedures; Cardiac Tamponade; Drug Therapy; Exudates and Transud

1965
[Comparison of preliminary results of involved-field with extended field radiotherapy combined with chemotherapy for early stage Hodgkin's disease].
    Zhonghua zhong liu za zhi [Chinese journal of oncology], 2006, Volume: 28, Issue:3

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Combined Modalit

2006
[Treatment results of stage IA Hodgkin lymphoma: a report of 97 cases].
    Ai zheng = Aizheng = Chinese journal of cancer, 2007, Volume: 26, Issue:12

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Co

2007
[Peculiarities of the recurrence of lymphogranulomatosis in children following combined chemotherapy].
    Voprosy onkologii, 1983, Volume: 29, Issue:8

    Topics: Age Factors; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Child; Cyclophos

1983
Treatment of early stage Hodgkin's disease with radiation therapy plus short-cycle (3 MOPP) adjuvant chemotherapy.
    Tumori, 1983, Oct-31, Volume: 69, Issue:5

    Topics: Age Factors; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Evaluation S

1983
Treatment of advanced malignant melanoma with high-dose chemotherapy and autologous bone marrow transplantation. Preliminary results--Phase I study.
    American journal of clinical oncology, 1982, Volume: 5, Issue:6

    Topics: Adolescent; Adult; Antineoplastic Agents; Bone Marrow Transplantation; Brain Neoplasms; Carmustine;

1982
Regional chemotherapy for melanoma. A 35-year experience.
    Annals of surgery, 1994, Volume: 220, Issue:4

    Topics: Adult; Aged; Chemotherapy, Cancer, Regional Perfusion; Clinical Trials as Topic; Combined Modality T

1994
Clinical characteristics and long-term outcome of patients with generalized patch and/or plaque (T2) mycosis fungoides.
    Archives of dermatology, 1999, Volume: 135, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Cause of Death; Disease Progression; Female; Humans; Lymph Nodes; Ly

1999
Relationship of cell type and lymph node metastasis to survival after resection of bronchial carcinoma.
    The Annals of thoracic surgery, 1975, Volume: 20, Issue:5

    Topics: Adenocarcinoma; Adult; Aged; Bronchial Neoplasms; Carcinoma, Small Cell; Carcinoma, Squamous Cell; C

1975
Management of Hodgkin's disease.
    Comprehensive therapy, 1979, Volume: 5, Issue:2

    Topics: Adolescent; Adult; Antineoplastic Agents; Drug Therapy, Combination; Hodgkin Disease; Humans; Lympha

1979
Chemotherapeutic agents and estradiol receptor binding capacity.
    Oncology, 1979, Volume: 36, Issue:4

    Topics: Animals; Antineoplastic Agents; Breast Neoplasms; Carcinoma; Dianhydrogalactitol; Estradiol; Female;

1979
Topical chemotherapy and immunotherapy of mycosis fungoides: intermediate-term results.
    Archives of dermatology, 1977, Volume: 113, Issue:4

    Topics: Administration, Topical; Aged; Desensitization, Immunologic; Dinitrochlorobenzene; Drug Hypersensiti

1977
Treatment of advanced stage mycosis fungoides with bleomycin, doxorubicin, and methotrexate with topical nitrogen mustard (BAM-M).
    Cancer, 1986, Dec-15, Volume: 58, Issue:12

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Chemical and Drug Induced Li

1986
Treatment of Hodgkin's disease in children with or without radiotherapy.
    Cancer, 1987, Jun-01, Volume: 59, Issue:11

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Child; Child, Preschool; Daca

1987
Total lymphoid irradiation, high-dose chemotherapy and autologous bone marrow transplantation for chemotherapy-resistant Hodgkin's disease.
    International journal of radiation oncology, biology, physics, 1989, Volume: 17, Issue:5

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Bone Marrow Transplantation; Combi

1989
Wide-field radiation therapy alone or with chemotherapy for Hodgkin's disease in relapse from combination chemotherapy.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1987, Volume: 5, Issue:4

    Topics: Actuarial Analysis; Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Child, Presch

1987
Mycosis fungoides: management with topical nitrogen mustard.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1987, Volume: 5, Issue:11

    Topics: Adult; Aged; Aged, 80 and over; Drug Evaluation; Female; Humans; Lymphatic Metastasis; Male; Mechlor

1987
Regional isolated limb perfusion of melanoma intransit metastases using mechlorethamine (nitrogen mustard).
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1986, Volume: 4, Issue:12

    Topics: Adult; Aged; Chemotherapy, Cancer, Regional Perfusion; Extremities; Female; Humans; Hyperthermia, In

1986
Effect of therapy on the serum level of alpha-1 fetoprotein in embryonal cell carcinoma.
    The Journal of pediatrics, 1972, Volume: 81, Issue:1

    Topics: Alpha-Globulins; Child, Preschool; Cyclophosphamide; Dactinomycin; Fetal Proteins; Humans; Immunodif

1972
Conservative mediastinal node dissection for the treatment of carcinoma of the breast.
    Surgery, gynecology & obstetrics, 1973, Volume: 136, Issue:3

    Topics: Adult; Aged; Breast Neoplasms; California; Carcinoma, Intraductal, Noninfiltrating; Evaluation Studi

1973
Primary liver carcinoma.
    Cancer, 1974, Volume: 33, Issue:6

    Topics: Adolescent; Adrenal Gland Neoplasms; Adult; Aged; Biopsy; Bone Neoplasms; Carcinoma, Hepatocellular;

1974
In vitro estimate of sensitivity of individual human tumors to antitumor agents.
    Oncology, 1974, Volume: 30, Issue:1

    Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Arsenicals; Benzoates; Breast Neoplasms; Carbon Radi

1974
[False facial cellulitis: hematosarcoma].
    Revue de stomatologie et de chirurgie maxillo-faciale, 1973, Volume: 74, Issue:2

    Topics: Cellulitis; Diagnosis, Differential; Drug Therapy, Combination; Facial Neoplasms; Humans; Hydrazines

1973
Mechanisms of lymphorrhage into the serous cavities with description of a case.
    Polish medical journal, 1972, Volume: 11, Issue:5

    Topics: Adult; Anti-Bacterial Agents; Chylothorax; Chylous Ascites; Cyclophosphamide; Dexamethasone; Drainag

1972
[Chylous effusion during reticulosarcoma].
    La Nouvelle presse medicale, 1973, Jan-13, Volume: 2, Issue:2

    Topics: Abdominal Neoplasms; Chylothorax; Humans; Hydrazines; Inguinal Canal; Lumbosacral Region; Lymphatic

1973
[Chemotherapy in the terminal stages of tumors].
    Voprosy onkologii, 1968, Volume: 14, Issue:6

    Topics: Alkylating Agents; Bone Neoplasms; Cyclophosphamide; Dysgerminoma; Lymphatic Metastasis; Lymphoma, L

1968
[Results of treatment of tonsillar tumors by olivomycin].
    Antibiotiki, 1969, Volume: 14, Issue:3

    Topics: Adolescent; Adult; Antibiotics, Antineoplastic; Carcinoma, Squamous Cell; Chlorpromazine; Cyclophosp

1969
Lymphatic extension of carcinoma of the lung to the anterior chest wall.
    American journal of surgery, 1965, Volume: 110, Issue:6

    Topics: Biopsy; Carcinoma, Squamous Cell; Cobalt Isotopes; Humans; Lung Neoplasms; Lymph Node Excision; Lymp

1965