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mechlorethamine and Lupus Nephritis

mechlorethamine has been researched along with Lupus Nephritis in 5 studies

nitrogen mustard : Compounds having two beta-haloalkyl groups bound to a nitrogen atom, as in (X-CH2-CH2)2NR.

Lupus Nephritis: Glomerulonephritis associated with autoimmune disease SYSTEMIC LUPUS ERYTHEMATOSUS. Lupus nephritis is histologically classified into 6 classes: class I - normal glomeruli, class II - pure mesangial alterations, class III - focal segmental glomerulonephritis, class IV - diffuse glomerulonephritis, class V - diffuse membranous glomerulonephritis, and class VI - advanced sclerosing glomerulonephritis (The World Health Organization classification 1982).

Research Excerpts

ExcerptRelevanceReference
"Twenty-two patients with histologically demonstrated diffuse proliferative lupus nephritis (DPLN) and glomerular thrombosis received a 14-day course of ancrod, followed in most by nitrogen mustard (mechlorethamine hydrochloride) 0."3.68Diffuse proliferative lupus nephritis: long-term observations in patients treated with ancrod. ( Hariharan, S; Kant, KS; Pollak, VE; Wadhwa, NK; Weiss, MA, 1990)
"Risk of ESRD by WHO class at 5 years was as follows: class III, 0%; IV, 9%; V, 16% (P = ."1.29Lupus in the 1980s: III. Influence of clinical variables, biopsy, and treatment on the outcome in 150 patients with lupus nephritis seen at a single center. ( Azen, C; Fichman, M; Klinenberg, JR; Metzger, AL; Nessim, S; Neumann, K; Wallace, DJ, 1995)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19902 (40.00)18.7374
1990's3 (60.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
WILSON, RM1
MAHER, JF1
SCHREINER, GE1
Wallace, DJ2
Metzger, AL2
Neumann, K1
Azen, C1
Nessim, S1
Fichman, M1
Klinenberg, JR1
Hariharan, S1
Pollak, VE1
Kant, KS1
Weiss, MA1
Wadhwa, NK1
Dillard, MG1

Other Studies

5 other studies available for mechlorethamine and Lupus Nephritis

ArticleYear
Lupus nephritis. Clinical and histologic survey.
    Archives of internal medicine, 1963, Volume: 111

    Topics: Adrenocorticotropic Hormone; Humans; Lupus Erythematosus, Systemic; Lupus Nephritis; Mechlorethamine

1963
Successful use of nitrogen mustard for cyclophosphamide resistant diffuse proliferative lupus glomerulonephritis: report of 2 cases.
    The Journal of rheumatology, 1995, Volume: 22, Issue:4

    Topics: Adolescent; Adult; Cyclophosphamide; Drug Resistance; Female; Glomerulonephritis; Humans; Lupus Neph

1995
Lupus in the 1980s: III. Influence of clinical variables, biopsy, and treatment on the outcome in 150 patients with lupus nephritis seen at a single center.
    Seminars in arthritis and rheumatism, 1995, Volume: 25, Issue:1

    Topics: Adult; Anti-Inflammatory Agents; Azathioprine; Biopsy; Blood Component Removal; Chlorambucil; Cyclop

1995
Diffuse proliferative lupus nephritis: long-term observations in patients treated with ancrod.
    Clinical nephrology, 1990, Volume: 34, Issue:2

    Topics: Adult; Ancrod; Blood Pressure; Creatinine; Drug Therapy, Combination; Female; Follow-Up Studies; Hum

1990
Systemic lupus erythematosus--the nephrologist's viewpoint.
    Transplantation proceedings, 1987, Volume: 19, Issue:2 Suppl 2

    Topics: Azathioprine; Cyclophosphamide; Female; Humans; Lupus Nephritis; Male; Mechlorethamine; Prednisone;

1987
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