mechlorethamine has been researched along with Leukopenia in 100 studies
nitrogen mustard : Compounds having two beta-haloalkyl groups bound to a nitrogen atom, as in (X-CH2-CH2)2NR.
Leukopenia: A decrease in the number of LEUKOCYTES in a blood sample below the normal range (LEUKOCYTE COUNT less than 4000).
| Excerpt | Relevance | Reference |
|---|---|---|
| "We undertook a phase II study of combination chemotherapy with mechlorethamine (nitrogen mustard) 6 mg/m2 intravenously day 1 and day 8, vincristine 2 mg intravenously day 1 and day 8, and procarbazine 100 mg/m2 orally days 1 through 14 (MOP) in adults with recurrent high-grade glioma." | 9.06 | Mechlorethamine, vincristine, and procarbazine chemotherapy for recurrent high-grade glioma in adults: a phase II study. ( Baptista, J; Clark, K; Coyle, T; Graziano, S; King, R; Kirshner, J; Newman-Palmer, N; Poiesz, B; Scalzo, A; Winfield, J, 1990) |
| "We undertook a phase II study of combination chemotherapy with mechlorethamine (nitrogen mustard) 6 mg/m2 intravenously day 1 and day 8, vincristine 2 mg intravenously day 1 and day 8, and procarbazine 100 mg/m2 orally days 1 through 14 (MOP) in adults with recurrent high-grade glioma." | 5.06 | Mechlorethamine, vincristine, and procarbazine chemotherapy for recurrent high-grade glioma in adults: a phase II study. ( Baptista, J; Clark, K; Coyle, T; Graziano, S; King, R; Kirshner, J; Newman-Palmer, N; Poiesz, B; Scalzo, A; Winfield, J, 1990) |
| " WIR-induced mucosal lesion formation was significantly inhibited in animals given iloprost, a stable analog of PGI2, and in those with nitrogen mustard-induced leukocytopenia." | 3.69 | Novel role of prostacyclin in stress-induced gastric mucosal lesion formation in rats. ( Harada, N; Murakami, K; Okabe, H; Okajima, K; Takatsuki, K; Tanaka, K; Uchiba, M, 1997) |
| "Rabbits with endocarditis caused by Staphylococcus epidermidis were studied to determine the parts played by granulocytes and monocytes in the prevention or outcome of therapy with cloxacillin." | 3.67 | Role of granulocytes and monocytes in the prevention and therapy of experimental Staphylococcus epidermidis endocarditis in rabbits. ( Mattie, H; Meddens, MJ; Thompson, J; van Furth, R, 1985) |
| "Thirty-four children with Hodgkin's disease were treated during the years 1969--75." | 2.64 | MVPP chemotherapy combined with radiotherapy in the treatment of Hodgkin's disease in children. ( Armata, J; Borkowski, W; Depowska, T; Depowski, M; Kaczor, Z; Stopyrowa, J; Strzeszynski, J, 1978) |
| "Of 6 patients who developed recurrence, 3 (7." | 1.33 | [Comparison of preliminary results of involved-field with extended field radiotherapy combined with chemotherapy for early stage Hodgkin's disease]. ( Han, JZ; Jin, J; Li, YX; Liu, XF; Liu, YP; Song, YW; Wang, SL; Wang, WH; Yu, ZH; Zhou, LQ, 2006) |
| "Melatonin was shown to play an important role in protecting animal cells from neutrophil-induced toxicity and damage by free radicals." | 1.31 | Potent protective effects of melatonin on experimental spinal cord injury. ( Fujimoto, T; Ikeda, T; Nakamura, T; Takagi, K, 2000) |
| "Gabexate mesilate is a synthetic protease inhibitor capable of inhibiting both coagulation and cytokine production by monocytes." | 1.30 | Gabexate mesilate, a synthetic protease inhibitor, prevents compression-induced spinal cord injury by inhibiting activation of leukocytes in rats. ( Johno, M; Kushimoto, S; Murakami, K; Naruo, M; Okabe, H; Okajima, K; Takatsuki, K; Taoka, Y; Uchiba, M, 1997) |
| "Treatment with indomethacin before stress inhibited the increase in 6-keto-PGF1alpha levels and markedly reduced mucosal blood flow." | 1.30 | Gastric prostacyclin (PGI2) prevents stress-induced gastric mucosal injury in rats primarily by inhibiting leukocyte activation. ( Harada, N; Isobe, H; Liu, W; Murakami, K; Okajima, K, 1999) |
| " From a dose-response showing that the administration of increasing doses of tissue thromboplastin resulted in a subsequent progressive increase of thrombus weight, two concentrations of tissue thromboplastin were chosen: a high dose (550 microL/kg, IV) where thrombus formation was optimal and a concentration (7 microL/kg, IV) where tissue thromboplastin-hypercoagulability was intermediate." | 1.28 | Importance of platelets in experimental venous thrombosis in the rat. ( Bernat, A; Herbert, JM; Maffrand, JP, 1992) |
| "We chose listeriosis because resistance to Listeria monocytogenes occurs in two phases." | 1.27 | Models of T cell deficiency in listeriosis: the effects of cortisone and cyclosporin A on normal and nude BALB/c mice. ( Davis, CE; Douglas, H; Schaffner, A, 1983) |
| "One patient with Hodgkin's disease involving the liver is alive at 36 months with further therapy." | 1.26 | Adriamycin, bleomycin, DIC, CCNU, and prednisone (ABDIC) chemotherapy in MOPP-resistant Hodgkin's disease. ( Gamble, JF; Loh, KK; Rodgers, RW; Shullenberger, CC, 1980) |
| "Thirty-eight patients with advanced Hodgkin's disease were treated with a combination of cyclophosphamide, vinblastine, procarbazine, and prednisone (CVPP)." | 1.26 | Combinaed chemotherapy with cyclophosphamide, vinblastine, procarbazine, and prednisone (CVPP) for patients with advanced Hodgkin's disease. An alternative program to MOPP. ( Bloomfield, CD; Fortuny, I; Kennedy, BJ; Vosika, G; Weiss, RB, 1976) |
| "had positive reactions." | 1.24 | A comparison of the effects on the Shwartzman phenomenon of leukopenia produced by nitrogen mustard and by whole body irradiation. ( HOWLAND, JW; JOHNSTONE, DE, 1958) |
| "The inhibition of the Shwartzman phenomenon by nitrogen mustard and benzene has been confirmed and investigated further." | 1.23 | Studies on the mechanism of the Shwartzman-phenomenon; evidence for the participation of polymorphonuclear leucocytes in the phenomenon. ( GOOD, RA; STETSON, CA, 1951) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 78 (78.00) | 18.7374 |
| 1990's | 17 (17.00) | 18.2507 |
| 2000's | 5 (5.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Niu, Y | 1 |
| Shi, YK | 1 |
| He, XH | 1 |
| Feng, FY | 1 |
| Zhou, LQ | 2 |
| Gu, DZ | 1 |
| LEVINE, B | 2 |
| WEISBERGER, AS | 5 |
| STORAASLI, JP | 1 |
| SAKURAI, Y | 1 |
| MATSUI, E | 1 |
| BEVACQUA, V | 1 |
| GARAVAGLIA, GP | 1 |
| DUDIK, E | 1 |
| MASETTO, I | 1 |
| BUTTO, M | 1 |
| JOHNSTONE, DE | 1 |
| HOWLAND, JW | 1 |
| KURIAKI, K | 1 |
| HIYOSHI, K | 1 |
| MOROZOVA, EN | 1 |
| WAKIZAKA, J | 1 |
| YUGE, S | 1 |
| KAISER, GA | 1 |
| HERTER, FP | 1 |
| MARKOWITZ, AM | 1 |
| EVANS, S | 1 |
| ANDERSON, JM | 1 |
| YAMAMOTO, I | 1 |
| IWATSUBO, K | 1 |
| KIMURA, H | 1 |
| FILD, DB | 1 |
| MAIRLES, A | 1 |
| DOLENDO, ES | 1 |
| ROCHA, H | 1 |
| FEKETY, FR | 1 |
| MEYER, LM | 1 |
| FLIEDNER, TD | 1 |
| CRONKITE, EP | 1 |
| SUPPAN, A | 1 |
| UNEOBU, H | 1 |
| HIROO, T | 1 |
| FUJIMOTO, S | 1 |
| TATEBE, T | 1 |
| EISMAN, SG | 1 |
| RICHARDSON, FM | 1 |
| NORIN, T | 1 |
| BEAHRS, OH | 1 |
| CALDAROLA, VT | 1 |
| HARRISON, EG | 1 |
| SCHMIDT, D | 1 |
| CLAPP, P | 2 |
| TAYAO, MS | 2 |
| MILLER, DG | 2 |
| LAWRENCE, W | 2 |
| HERION, JC | 2 |
| HERRING, WB | 2 |
| PALMER, JG | 2 |
| WALKER, RI | 2 |
| MAHAJAN, RD | 1 |
| PAGE, R | 1 |
| ALLEN, IV | 1 |
| FIELD, JB | 1 |
| DOLENDO, EC | 1 |
| MIRELES, A | 1 |
| ERSHOFF, BH | 1 |
| BARRAN, KM | 1 |
| HELM, WH | 1 |
| KING, DA | 1 |
| HEINLE, RW | 3 |
| STETSON, CA | 1 |
| GOOD, RA | 1 |
| TAZAKI, Y | 1 |
| FUCHIGAMI, A | 1 |
| OOTA, K | 1 |
| Yamanaka, R | 1 |
| Morii, K | 1 |
| Shinbo, Y | 1 |
| Takeuchi, S | 1 |
| Tamura, T | 1 |
| Hondoh, H | 1 |
| Takahashi, H | 2 |
| Onda, K | 1 |
| Tanaka, R | 1 |
| Wang, WH | 1 |
| Li, YX | 1 |
| Song, YW | 1 |
| Jin, J | 1 |
| Liu, YP | 1 |
| Wang, SL | 1 |
| Liu, XF | 1 |
| Yu, ZH | 1 |
| Han, JZ | 1 |
| Uriuhara, T | 1 |
| Movat, HZ | 1 |
| Orange, RP | 1 |
| Valentine, MD | 1 |
| Austen, KF | 1 |
| Rodgers, RW | 1 |
| Gamble, JF | 1 |
| Loh, KK | 1 |
| Shullenberger, CC | 1 |
| Holdsworth, SR | 1 |
| Bogman, MJ | 1 |
| Cornelissen, IM | 1 |
| Berden, JH | 1 |
| De Jong, J | 1 |
| Koene, RA | 1 |
| Armata, J | 2 |
| Cyklis, R | 1 |
| Grześkowiak-Melanowska, J | 1 |
| Fisher, RI | 1 |
| DeVita, VT | 2 |
| Hubbard, SM | 1 |
| Longo, DL | 1 |
| Wesley, R | 1 |
| Chabner, BA | 1 |
| Young, RC | 1 |
| Schaffner, A | 1 |
| Douglas, H | 1 |
| Davis, CE | 1 |
| Wagener, DJ | 1 |
| Burgers, JM | 1 |
| Dekker, AW | 1 |
| Kazem, I | 1 |
| van Peperzeel, HA | 1 |
| Qasim, MM | 1 |
| Sizoo, W | 1 |
| Somers, R | 1 |
| Kroese, WF | 1 |
| Shamberger, RC | 1 |
| Devereux, DF | 1 |
| Brennan, MF | 1 |
| Yersin, BR | 1 |
| Glauser, MP | 1 |
| Freedman, LR | 1 |
| Flick, MR | 1 |
| Perel, A | 1 |
| Staub, NC | 1 |
| Canellos, GP | 1 |
| Petroni, GR | 1 |
| Barcos, M | 1 |
| Duggan, DB | 1 |
| Peterson, BA | 1 |
| Goldman, G | 1 |
| Welbourn, R | 1 |
| Klausner, JM | 1 |
| Kobzik, L | 1 |
| Valeri, CR | 1 |
| Shepro, D | 1 |
| Hechtman, HB | 1 |
| Murakami, K | 8 |
| Okajima, K | 9 |
| Uchiba, M | 6 |
| Johno, M | 5 |
| Nakagaki, T | 1 |
| Okabe, H | 4 |
| Takatsuki, K | 4 |
| Taoka, Y | 4 |
| Harada, N | 5 |
| Naruo, M | 4 |
| Tanaka, K | 1 |
| Kushimoto, S | 1 |
| Dunlop, DJ | 1 |
| Eatock, MM | 1 |
| Paul, J | 1 |
| Anderson, S | 1 |
| Reed, NS | 1 |
| Soukop, M | 1 |
| Lucie, N | 1 |
| Fitzsimmons, EJ | 1 |
| Tansey, P | 1 |
| Steward, WP | 1 |
| Liu, W | 2 |
| Isobe, H | 2 |
| Irie, T | 1 |
| Fujimoto, T | 1 |
| Nakamura, T | 1 |
| Ikeda, T | 1 |
| Takagi, K | 1 |
| Miller, AM | 1 |
| McPhaden, AR | 1 |
| Wadsworth, RM | 1 |
| Wainwright, CL | 1 |
| Bonadonna, G | 1 |
| De Lena, M | 1 |
| Lattuada, A | 1 |
| Milani, F | 1 |
| Monfardini, S | 1 |
| Beretta, G | 1 |
| Hansen, HH | 1 |
| Selawry, OS | 1 |
| Simon, R | 1 |
| Carr, DT | 1 |
| van Wyk, CE | 1 |
| Tucker, RD | 1 |
| Sealy, R | 1 |
| Stopyrowa, J | 1 |
| Depowski, M | 1 |
| Strzeszynski, J | 1 |
| Borkowski, W | 1 |
| Kaczor, Z | 1 |
| Depowska, T | 1 |
| Oblack, DL | 1 |
| Schwarz, J | 1 |
| Holder, IA | 1 |
| Bloomfield, CD | 1 |
| Weiss, RB | 1 |
| Fortuny, I | 1 |
| Vosika, G | 1 |
| Kennedy, BJ | 1 |
| Lipinski, B | 2 |
| Gurewich, V | 2 |
| Hyde, E | 1 |
| de Kreek, EJ | 1 |
| Sybesma, HB | 1 |
| Herbert, JM | 1 |
| Bernat, A | 1 |
| Maffrand, JP | 1 |
| Pérez-Tamayo, R | 2 |
| Becker, I | 2 |
| Montfort, I | 2 |
| Pérez-Montfort, R | 2 |
| Rowbotham, BJ | 1 |
| Whitaker, AN | 1 |
| Masci, PP | 1 |
| Martínez, RD | 1 |
| Olivos, A | 1 |
| Coyle, T | 1 |
| Baptista, J | 1 |
| Winfield, J | 1 |
| Clark, K | 1 |
| Poiesz, B | 1 |
| Kirshner, J | 1 |
| Scalzo, A | 1 |
| Newman-Palmer, N | 1 |
| King, R | 1 |
| Graziano, S | 1 |
| Pettipher, ER | 1 |
| Henderson, B | 1 |
| Hardingham, T | 1 |
| Ratcliffe, A | 1 |
| Albertine, KH | 1 |
| Basadre, JO | 1 |
| Sugi, K | 1 |
| Traber, DL | 1 |
| Traber, LD | 1 |
| Niehaus, GD | 1 |
| Herndon, DN | 1 |
| Schein, PS | 1 |
| Green, D | 1 |
| Dean, SW | 1 |
| McPherson, E | 1 |
| Meddens, MJ | 1 |
| Thompson, J | 1 |
| Mattie, H | 1 |
| van Furth, R | 1 |
| Cameron, JS | 1 |
| Boulton-Jones, M | 1 |
| Robinson, R | 1 |
| Ogg, C | 1 |
| Desser, RK | 1 |
| Ultmann, JE | 1 |
| Labie, C | 1 |
| Le Bars, H | 1 |
| Baetz, P | 1 |
| Martinez, P | 1 |
| Attström, R | 1 |
| Egelberg, J | 1 |
| Solomon, J | 1 |
| Jacobs, EM | 1 |
| Bateman, JR | 1 |
| Lukes, RJ | 1 |
| Weiner, JM | 1 |
| Donohue, DM | 1 |
| Fairley, GH | 1 |
| Lowenbraun, S | 1 |
| Serpick, AA | 1 |
| Horan, AH | 1 |
| Cook, ES | 1 |
| Nutini, LG | 1 |
| Saslaw, S | 1 |
| Carlisle, HN | 1 |
| Karrar, K | 1 |
| DeConti, RC | 1 |
| Kaplan, SR | 1 |
| Calabresi, P | 1 |
| Bailey, EM | 1 |
| Picken, JC | 1 |
| Du Buy, B | 1 |
| McKinna, JA | 1 |
| Kardaszewicz, E | 1 |
| Japa, J | 1 |
| Fink, ME | 1 |
| Finch, SC | 1 |
| Vettori, G | 2 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Effects of Oral Melatonin on Neurosensory Recovery Following Facial Osteotomies - A Randomised, Controlled Clinical Trial[NCT02889432] | Phase 2 | 40 participants (Anticipated) | Interventional | 2016-06-30 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for mechlorethamine and Leukopenia
| Article | Year |
|---|---|
The effect of chemotherapeutic agents on wound healing.
Topics: Adrenal Cortex Hormones; Anemia; Animals; Antineoplastic Agents; Azathioprine; Collagen; Cyclophosph | 1981 |
The sensitivity of Hodgkin's disease to chemotherapeutic agents administered singly.
Topics: Adrenal Cortex Hormones; Alopecia; Antineoplastic Agents; Bleomycin; Blood Platelet Disorders; Carmu | 1973 |
7 trials available for mechlorethamine and Leukopenia
| Article | Year |
|---|---|
Etoposide, vinblastine, and doxorubicin: an active regimen for the treatment of Hodgkin's disease in relapse following MOPP. Cancer and Leukemia Group B.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Disease-Free Survival; Doxorubici | 1995 |
Randomized multicentre trial of filgrastim as an adjunct to combination chemotherapy for Hodgkin's disease. West of Scotland Lymphoma Group.
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Chemotherapy, | 1998 |
Combination chemotherapy and radiotherapy in non-Hodgkin's lymphomata.
Topics: Antineoplastic Agents; Bleomycin; Bone Marrow; Clinical Trials as Topic; Cyclophosphamide; Doxorubic | 1975 |
Combination chemotherapy of advanced lung cancer: a randomized trial.
Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Agents; Carcinoma, Bronchogenic; Carcinoma, Small Cell; | 1976 |
MVPP chemotherapy combined with radiotherapy in the treatment of Hodgkin's disease in children.
Topics: Adolescent; Antineoplastic Agents; Child; Child, Preschool; Clinical Trials as Topic; Drug Evaluatio | 1978 |
Mechlorethamine, vincristine, and procarbazine chemotherapy for recurrent high-grade glioma in adults: a phase II study.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Drug Administration Schedule; Female; G | 1990 |
Chemotherapy of lymphoma with mechlorethamine and vinblastine.
Topics: Adult; Blood Cell Count; Blood Platelet Disorders; Clinical Trials as Topic; Evaluation Studies as T | 1973 |
91 other studies available for mechlorethamine and Leukopenia
| Article | Year |
|---|---|
[Combined-modality therapy for 150 cases of early-stage Hodgkin's lymphoma].
Topics: Adolescent; Adult; Aged; Alopecia; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Child; | 2008 |
Augmentation of nitrogen mustard induced leukopenia by cortisone.
Topics: Cortisone; Leukocyte Disorders; Leukocytes; Leukopenia; Mechlorethamine | 1953 |
Optical isomers of cysteine in the prevention of leukopenia induced by nitrogen mustard.
Topics: Cysteine; Leukocyte Count; Leukocyte Disorders; Leukopenia; Mechlorethamine; Nitrogen Mustard Compou | 1954 |
[Effect of some sulfhydryl containing compounds on nitrogen mustard N-oxide induced leukopenia].
Topics: Leukocyte Count; Leukocyte Disorders; Leukopenia; Mechlorethamine; Nitrogen Mustard Compounds; Sulfh | 1954 |
[Inhibitory effect of cysteine on leukopenia produced by nitrogen mustard].
Topics: Cysteine; Leukocyte Count; Leukopenia; Mechlorethamine; Nitrogen Mustard Compounds | 1954 |
[Mitomen (nitrogen mustard oxide) causing leukopenia].
Topics: Leukocyte Count; Leukocyte Disorders; Leukopenia; Mechlorethamine; Nitrogen Mustard Compounds; Oxide | 1956 |
[Effect of massive doses of vitamin B12 on leucopenias caused by azoiprite].
Topics: Corrinoids; Leukocyte Count; Leukopenia; Mechlorethamine; Nitrogen Mustard Compounds; Vitamin B 12 | 1956 |
A comparison of the effects on the Shwartzman phenomenon of leukopenia produced by nitrogen mustard and by whole body irradiation.
Topics: Animals; Hypersensitivity; Leukocyte Count; Leukopenia; Mechlorethamine; Rabbits; Shwartzman Phenome | 1958 |
[Leukopenia and decrease of glutathione in the liver caused by nitrogen mustard oxide and protection by some sulfhydryl compounds of nucleic acids and their derivatives].
Topics: Glutathione; Leukocyte Count; Leukopenia; Liver; Mechlorethamine; Nitrogen Mustard Compounds; Nuclei | 1958 |
[The effect of pentoxyl on the lipids of the bone marrow of rabbits in experimental leukopenia].
Topics: Animals; Bone Marrow; Leukocyte Disorders; Leukopenia; Lipid Metabolism; Lipids; Mechlorethamine; Ni | 1961 |
[Measures against leukopenia in the chemotherapy of cancer. 2. A study of methods of administering antineoplastic agents].
Topics: Antineoplastic Agents; Leukopenia; Mechlorethamine; Neoplasms; Thiamine; Vitamin K; Vitamins | 1963 |
AUTOLOGOUS MARROW IN TREATMENT OF NITROGEN MUSTARD-INDUCED MARROW DEPRESSION.
Topics: Bone Marrow; Bone Marrow Transplantation; Depression; Dogs; Leukopenia; Mechlorethamine; Research; T | 1963 |
THE KINETICS OF THE SPECIFIC ANTAGONISM IN VIVO OF INTRA-ARTERIAL METHYL-BIS(BETA-CHLOROETHYL)AMINE HYDROCHLORIDE BY INTRAVENOUS SOLUTIONS OF HYDROUS SODIUM THIOSULFATE.
Topics: Amines; Animals; Dogs; Femoral Artery; Femoral Vein; Hematocrit; Infusions, Parenteral; Injections, | 1963 |
[STUDIES ON NITROGEN MUSTARD DERIVATIVES, WITH SPECIAL REFERENCE TO THE PHARMACOLOGICAL ACTION OF NITROGEN MUSTARD DERIVATIVES CONTAINING ONLY L BETA-CHLOROETHYL GROUP].
Topics: Analgesics; Analgesics, Non-Narcotic; Antipyretics; Ganglionic Blockers; Injections, Subcutaneous; L | 1963 |
[ATTENUATION OF THE TOXIC EFFECT OF EMBICHIN (HN2) WITH A SEROTONIN ANTAGONIST].
Topics: Epinephrine; Leukocyte Count; Leukopenia; Mechlorethamine; Mice; Pyrazoles; Selective Serotonin Reup | 1963 |
ACUTE INFLAMMATION IN THE RENAL CORTEX AND MEDULLA FOLLOWING THERMAL INJURY.
Topics: Animals; Burns; Burns, Electric; Escherichia coli; Escherichia coli Infections; Hydronephrosis; Infl | 1964 |
AUTOLOGOUS BONE-MARROW TRANSFUSION FOLLOWING CHEMOTHERAPY.
Topics: Autoradiography; Biomedical Research; Blood Cell Count; Blood Platelets; Bone Marrow; Bone Marrow Tr | 1964 |
[ON THE PROBLEM OF CYSTOSTATICS AND LEUKOPENIA].
Topics: Antineoplastic Agents; Autonomic Nervous System Diseases; Bone Marrow Examination; Cyclophosphamide; | 1964 |
[OBSERVATIONS ON THE LEUKOCYTOTIC ACTION OF 2-(ALPHA-PHENYL-2-CARBETHOXYMETHYL)-THIAZOLIDINE-4-CARBOXYLIC ACID].
Topics: Blood; Leukocytes; Leukocytosis; Leukopenia; Mechlorethamine; Pharmacology; Rabbits; Research; Thiaz | 1964 |
CANCER CHEMOTHERAPY.
Topics: Adrenal Cortex Hormones; Aminopterin; Androgens; Antimetabolites; Antineoplastic Agents; Blood Plate | 1964 |
MELPHALAN (PHENYLALANIN NITROGEN MUSTARD) -TREATMENT IN MYELOMATOSIS.
Topics: Albuminuria; Blood Protein Electrophoresis; Humans; Leukocyte Disorders; Leukopenia; Mechlorethamine | 1964 |
TREATMENT OF CANCER OF THE HEAD AND NECK BY CHEMOTHERAPY.
Topics: Alopecia; Diarrhea; Erythema; Head; Head and Neck Neoplasms; Injections, Intra-Arterial; Leukopenia; | 1964 |
[ON AN ATTEMPT AT COMPENSATION OF LEUKOTOXIC SIDE-EFFECTS DURING THE USE OF CYTOSTATICS, BY SUBSTANCES FROM THE TISSUE- OR CELLULAR THERAPY GROUP].
Topics: Cell- and Tissue-Based Therapy; Cytostatic Agents; Leukopenia; Mechlorethamine; Pharmacology; Rats; | 1964 |
RESULTS OF REGIONAL CHEMOTHERAPY OF NEOPLASMS OF THE UPPER BODY BY TEMPORARY MID-TORSO VASCULAR OCCLUSION.
Topics: Alkylating Agents; Bone Marrow; Breast Neoplasms; Catheterization; Chemotherapy, Cancer, Regional Pe | 1964 |
CR51-LABELED ENDOTOXIN DISTRIBUTION IN GRANULOCYTOPENIC ANIMALS.
Topics: Adipose Tissue; Biological Transport; Blood; Blood Platelets; Bone Marrow; Chromium Isotopes; Endoto | 1964 |
SYSTEMIC THIOSULFATE PROTECTION DURING FRACTIONATED REGIONAL NITROGEN MUSTARD THERAPY.
Topics: Biomedical Research; Carcinoma; Carcinoma, Squamous Cell; Dogs; Geriatrics; Infusions, Parenteral; I | 1964 |
THE EFFECT OF GRANULOCYTOPENIA ON EXPERIMENTAL TUBERCULIN FEVER.
Topics: Agranulocytosis; Fever; Hypersensitivity; Hypersensitivity, Delayed; Leukopenia; Lipopolysaccharides | 1965 |
INFLUENCE OF SEROTONIN ANTAGONISTS ON NITROGEN MUSTARD INTOXICATION.
Topics: Injections; Injections, Intraperitoneal; Leukopenia; Mechlorethamine; Mice; Pharmacology; Research; | 1965 |
EFFECTS OF ENDOTOXIN AND NITROGEN MUSTARD ON LEUKOCYTE KINETICS.
Topics: Bone Marrow Cells; Cell Division; Drug Tolerance; Endotoxins; Histology; Kinetics; Leukocyte Disorde | 1965 |
BRONCHIAL CARCINOMA TREATED WITH NITROGEN MUSTARD AND CYCLOPHOSPHAMIDE.
Topics: Adenocarcinoma; Bronchial Neoplasms; Carcinoid Tumor; Carcinoma; Carcinoma, Bronchogenic; Carcinoma, | 1965 |
The protective effect of cysteine on leucopenia induced by nitrogen mustard.
Topics: Cysteine; Leukocyte Disorders; Leukocytes; Leukopenia; Mechlorethamine; Nitrogen Mustard Compounds | 1950 |
Protective effect of cysteine against leucopenia induced by nitrogen mustard.
Topics: Cysteine; Leukocyte Disorders; Leukocytes; Leukopenia; Mechlorethamine; Nitrogen Mustard Compounds | 1950 |
Studies on the mechanism of the Shwartzman-phenomenon; evidence for the participation of polymorphonuclear leucocytes in the phenomenon.
Topics: Leukopenia; Mechlorethamine; Nitrogen Mustard Compounds; Shwartzman Phenomenon | 1951 |
Precipitous leucopenia in a N-mustard treated leukemia; (an autopsy case).
Topics: Autopsy; Humans; Leukemia; Leukemia, Myeloid; Leukopenia; Mechlorethamine; Mustard Plant; Nitrogen M | 1951 |
Some structural requirements for the prevention of leukopenia induced by nitrogen mustard.
Topics: Humans; Leukocytes; Leukopenia; Mechlorethamine | 1952 |
Modified ProMACE-MOPP hybrid regimen with moderate-dose methotrexate for patients with primary CNS lymphoma.
Topics: Adult; Aged; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Centra | 2005 |
[Comparison of preliminary results of involved-field with extended field radiotherapy combined with chemotherapy for early stage Hodgkin's disease].
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Combined Modalit | 2006 |
Role of PMN-leukocyte lysosomes in tissue injury, inflammation and hypersensitivity. V. Partial suppresssion in leukopenic rabbits of vascular hyper-permeability due to thermal injury.
Topics: Animals; Burns; Capillary Permeability; Inflammation; Leukopenia; Lysosomes; Mechlorethamine; Micros | 1967 |
Release of slow-reacting substance of anaphylaxis in the rat: polymorphonuclear leukocyte.
Topics: Anaphylaxis; Animals; Antigens; Complement System Proteins; Inflammation; Leukopenia; Male; Mast Cel | 1967 |
Adriamycin, bleomycin, DIC, CCNU, and prednisone (ABDIC) chemotherapy in MOPP-resistant Hodgkin's disease.
Topics: Adolescent; Adult; Aged; Antineoplastic Agents; Bleomycin; Dacarbazine; Doxorubicin; Drug Administra | 1980 |
Fc dependence of macrophage accumulation and subsequent injury in experimental glomerulonephritis.
Topics: Animals; Complement System Proteins; Fluorescent Antibody Technique; Glomerulonephritis; Kidney; Kid | 1983 |
A comparative study of total body irradiation as a method of inducing granulocyte depletion in mice.
Topics: Animals; Complement System Proteins; Goats; Immune Sera; Leukocyte Count; Leukopenia; Mechlorethamin | 1984 |
[Effect of splenectomy on the leukocyte count during the treatment of children with Hodgkin's disease].
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Hodgkin Disease | 1984 |
Diffuse aggressive lymphomas: increased survival after alternating flexible sequences of proMACE and MOPP chemotherapy.
Topics: Adolescent; Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bloo | 1983 |
Models of T cell deficiency in listeriosis: the effects of cortisone and cyclosporin A on normal and nude BALB/c mice.
Topics: Animals; Bone Marrow; Cortisone; Cyclosporins; Disease Models, Animal; Female; Immunologic Deficienc | 1983 |
Sequential non-cross-resistant chemotherapy regimens (MOPP and CAVmP) in Hodgkin's disease stage IIIB and IV.
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; | 1983 |
Effect of nitrogen mustard on natural history of right-sided streptococcal endocarditis in rabbits: role for cellular host defenses.
Topics: Agranulocytosis; Animals; Endocarditis, Bacterial; Granulocytes; Leukocytes; Leukopenia; Mechloretha | 1982 |
Leukocytes are required for increased lung microvascular permeability after microembolization in sheep.
Topics: Animals; Body Water; Capillary Permeability; Embolism, Air; Female; Hemodynamics; Leukocytes; Leukop | 1981 |
Leukocytes mediate acid aspiration-induced multiorgan edema.
Topics: Animals; Edema; Hydrochloric Acid; Hydrogen Peroxide; Kidney; Leukopenia; Lung; Male; Mechlorethamin | 1993 |
Activated protein C prevents LPS-induced pulmonary vascular injury by inhibiting cytokine production.
Topics: Amino Acid Chloromethyl Ketones; Animals; Anticoagulants; Antithrombins; Blood Vessels; Cytokines; F | 1997 |
Reduction of spinal cord injury by administration of iloprost, a stable prostacyclin analog.
Topics: Animals; Epoprostenol; Iloprost; Leukopenia; Male; Mechlorethamine; Peroxidase; Rats; Rats, Wistar; | 1997 |
Novel role of prostacyclin in stress-induced gastric mucosal lesion formation in rats.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase | 1997 |
Gabexate mesilate, a synthetic protease inhibitor, prevents compression-induced spinal cord injury by inhibiting activation of leukocytes in rats.
Topics: Amino Acid Chloromethyl Ketones; Animals; Anticoagulants; Antithrombins; Factor Xa; Gabexate; Hepari | 1997 |
Activated protein C reduces the severity of compression-induced spinal cord injury in rats by inhibiting activation of leukocytes.
Topics: Animals; Anticoagulants; Leukocytes; Leukopenia; Male; Mechlorethamine; Peroxidase; Protein C; Rats; | 1998 |
Antithrombin III (AT III) prevents LPS-induced pulmonary vascular injury: novel biological activity of AT III.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Anticoagulants; Antithrombin III; Blood Coagulation Disorders | 1997 |
Role of neutrophil elastase in compression-induced spinal cord injury in rats.
Topics: Animals; Cephalosporins; Leukocyte Elastase; Leukopenia; Male; Mechlorethamine; Peroxidase; Proteins | 1998 |
Role of neutrophil elastase in stress-induced gastric mucosal injury in rats.
Topics: Animals; Capillary Permeability; Cephalosporins; Disease Models, Animal; Gastric Mucosa; Glycine; Le | 1998 |
Gastric prostacyclin (PGI2) prevents stress-induced gastric mucosal injury in rats primarily by inhibiting leukocyte activation.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Anti-Inflammatory Agents, Non-Steroidal; Epoprostenol; Gastri | 1999 |
Potent protective effects of melatonin on experimental spinal cord injury.
Topics: Animals; Leukopenia; Lipid Peroxidation; Locomotion; Male; Mechlorethamine; Melatonin; Peroxidase; R | 2000 |
Inhibition by leukocyte depletion of neointima formation after balloon angioplasty in a rabbit model of restenosis.
Topics: Angioplasty, Balloon; Animals; Antibodies, Monoclonal; Arterial Occlusive Diseases; Cell Adhesion; F | 2001 |
Enhancement of tissue damage by Candida albicans in cortisone or nitrogen mustard-treated mice.
Topics: Animals; Candidiasis; Cortisone; Creatine Kinase; Female; Kidney; Leukopenia; Mechlorethamine; Mice; | 1979 |
Combinaed chemotherapy with cyclophosphamide, vinblastine, procarbazine, and prednisone (CVPP) for patients with advanced Hodgkin's disease. An alternative program to MOPP.
Topics: Adolescent; Adult; Age Factors; Aged; Alopecia; Antineoplastic Agents; Cyclophosphamide; Drug Therap | 1976 |
Thrombin elaboration in endotoxin-induced intravascular fibrin deposition. A leukocyte dependent process distinct from systemic hypercoagulability.
Topics: Animals; Blood Coagulation Disorders; Blood Vessels; Disseminated Intravascular Coagulation; Endotox | 1976 |
[From tumors to scales].
Topics: Agranulocytosis; Humans; Immunologic Deficiency Syndromes; Leg Ulcer; Leukopenia; Male; Mechloretham | 1975 |
The effect of leukopenia versus thrombocytopenia on endotoxin induced intravascular coagulation.
Topics: Animals; Blood Cell Count; Blood Platelets; Disseminated Intravascular Coagulation; Drug Interaction | 1976 |
Importance of platelets in experimental venous thrombosis in the rat.
Topics: Animals; Blood Platelets; Clopidogrel; Disease Models, Animal; Heparin; Hirudins; Leukopenia; Male; | 1992 |
[Role of leukocytes and amebic proteases in experimental testicular necrosis produced in the rat by Entamoeba histolytica].
Topics: alpha-Macroglobulins; Animals; Endopeptidases; Entamoeba histolytica; Entamoebiasis; Leukopenia; Mal | 1990 |
Plasma cross-linked fibrin degradation product (XLFbDP) assays in an in vivo model of fibrinolysis.
Topics: Aminocaproic Acid; Animals; Antibodies, Monoclonal; Fibrin; Fibrin Fibrinogen Degradation Products; | 1990 |
[The mechanism of natural resistance in the rat to Entamoeba histolytica].
Topics: Animals; Complement System Proteins; Cricetinae; Entamoeba histolytica; Entamoebiasis; Female; Immun | 1990 |
Cartilage proteoglycan depletion in acute and chronic antigen-induced arthritis.
Topics: Animals; Antigens; Arthritis; Arthritis, Experimental; Cartilage, Articular; Glycosaminoglycans; Imm | 1989 |
Lung injury and neutrophil density during air embolization in sheep after leukocyte depletion with nitrogen mustard.
Topics: Animals; Arteries; Capillaries; Cell Count; Embolism, Air; Endothelium; Leukocyte Count; Leukocytes; | 1988 |
The effect of leukocyte depletion on smoke inhalation injury in sheep.
Topics: Animals; Burns, Inhalation; Capillary Permeability; Hemodynamics; Leukopenia; Lymph; Mechlorethamine | 1988 |
6-[Bis(2-chloroethyl)amino]-6-deoxygalactopyranose hydrochloride (C6-galactose mustard), a new alkylating agent with reduced bone marrow toxicity.
Topics: Animals; Bone Marrow; DNA Replication; Drug Evaluation, Preclinical; Female; Galactosamine; Hematopo | 1987 |
Role of granulocytes and monocytes in the prevention and therapy of experimental Staphylococcus epidermidis endocarditis in rabbits.
Topics: Animals; Blood Bactericidal Activity; Cloxacillin; Endocarditis; Endocarditis, Bacterial; Etoposide; | 1985 |
Treatment of lupus nephritis with cyclophosphamide.
Topics: Adolescent; Adult; Age Factors; Azathioprine; Biopsy; Chlorambucil; Cortisone; Cyclophosphamide; Fem | 1970 |
[Study of the activity of a phytohemagglutinin on the bone marrow of the rabbit subjected to experimental leukopenia and on the splenic reticulo-histiocytic system of the rat].
Topics: Animals; Bone Marrow; Lectins; Leukopenia; Mechlorethamine; Mononuclear Phagocyte System; Rats; Sple | 1967 |
Effect of experimental leukopenia on chronic gingival inflammation in dogs. 1. Induction of leukopenia by nitrogen mustard.
Topics: Animals; Chronic Disease; Dogs; Gingivitis; Leukopenia; Mechlorethamine; Muramidase | 1971 |
The use of different drugs and combinations in the treatment of Hodgkin's disease.
Topics: Administration, Oral; Anemia; Drug Evaluation; Drug Therapy, Combination; Hodgkin Disease; Humans; I | 1973 |
Combination chemotherapy with nitrogen mustard, vincristine, procarbazine, and prednisone in lymphosarcoma and reticulum cell sarcoma.
Topics: Adult; Aged; Antineoplastic Agents; Benzoates; Bone Marrow; Female; Follow-Up Studies; Humans; Leuko | 1970 |
The suppression of inflammatory edema at the nidation site by sodium salicylate and nitrogen mustard in the rat.
Topics: Animals; Anti-Inflammatory Agents; Capillary Permeability; Decidua; Depression, Chemical; Dye Diluti | 1971 |
Counteraction of leukopenia caused by mechlorethamine and azathioprine.
Topics: Animals; Antineoplastic Agents; Azathioprine; Dogs; Erythrocyte Count; Female; Kidney Transplantatio | 1971 |
Nonhuman primates in evaluation of hematotoxicity.
Topics: Animals; Busulfan; Chlorambucil; Cyclophosphamide; Dactinomycin; Drug-Related Side Effects and Adver | 1969 |
Importance of dose schedules in adjuvant chemotherapy.
Topics: Administration, Oral; Antineoplastic Agents; Bronchial Neoplasms; Cyclophosphamide; Evaluation Studi | 1972 |
Endotoxin stimulation in patients with lymphoma: correlation with the myelosuppressive effects of alkylating agents.
Topics: Agranulocytosis; Alkylating Agents; Bone Marrow Cells; Bone Marrow Examination; Cyclophosphamide; En | 1972 |
Effects of two alkylating agents in calves.
Topics: Alkylating Agents; Animals; Biological Assay; Blood Cells; Blood Proteins; Body Weight; Cattle; Catt | 1971 |
Role of the granulocyte in the pyrogenic response to intra-cisternal endotoxin.
Topics: Animals; Endotoxins; Escherichia coli; Fever; Leukocytes; Leukopenia; Mechlorethamine; Pyrogens; Rab | 1966 |
The use of chemotherapy in advanced carcinoma of the rectum.
Topics: Cyclophosphamide; Fluorouracil; Humans; Injections, Intra-Arterial; Leukopenia; Male; Mechlorethamin | 1969 |
[Effect of long-term immunosuppressive treatment on the hematopoietic system].
Topics: Anemia, Aplastic; Azathioprine; Hematopoiesis; Hematopoietic System; Humans; Immunosuppressive Agent | 1970 |
Serum muramidase and granulocyte turnover.
Topics: Agranulocytosis; Immune Sera; Leukocytes; Leukopenia; Mechlorethamine; Muramidase; Time Factors | 1968 |
[Action of phytohemagglutinins on experimental leukopenias produced by antitumor chemotherapy. I. Studies in the rabbit].
Topics: Animals; Antineoplastic Agents; Busulfan; Cyclophosphamide; Lectins; Leukopenia; Mechlorethamine; Ra | 1968 |
[Action of phytoagglutinins on experimental leukopenias produced by antitumor chemotherapy. II. Studies in the rat].
Topics: Animals; Antineoplastic Agents; Lectins; Leukopenia; Mechlorethamine; Rats | 1968 |