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mechlorethamine and Leukemia, Lymphocytic

mechlorethamine has been researched along with Leukemia, Lymphocytic in 61 studies

nitrogen mustard : Compounds having two beta-haloalkyl groups bound to a nitrogen atom, as in (X-CH2-CH2)2NR.

Research Excerpts

ExcerptRelevanceReference
"The effect of morphine and cocaine on the transport of hydrolyzed nitrogen mustard (NH2-OH) and choline by peripheral blood cells of normal subjects and patients with chronic lymphocytic leukemia, acute lymphoblastic leukemia, and acute myeloblastic leukemia was determined."3.65Drug-induced stimulation of transport of hydrolyzed nitrogen mustard and choline by normal and leukemic human cells in vitro. ( Goldenberg, GJ, 1976)

Research

Studies (61)

TimeframeStudies, this research(%)All Research%
pre-199061 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
KLIMA, R1
HORNISCHER, R1
BERNARD, J2
MATHE, G2
WEIL, M2
HANSEN, PB1
LAMY, P1
REMIGY, E1
STEHLIN, H1
ZULIK, R1
SCHREK, R3
FRIEDMAN, IA1
LEITHOLD, L1
LAWKOWICZ, W1
BECALSKI, J1
FURMAN, GJ1
ACKERMAN, GA2
COHEN, C1
GALTON, DA1
WILTSHAW, E1
SZUR, L1
DACIE, JV1
SPRAGUE, CC1
THEOLOGIDES, A1
KENNEDY, BJ1
HILGER, E1
EVANS, AM1
RIEKHOF, P1
STEFANI, S1
ADAMS, JL1
CREPALDI, G1
PARPAJOLA, A1
BURNINGHAM, RA1
RESTREPO, A1
PUGH, RP1
BROWN, EB1
SCHLOSSMAN, SF1
KHURI, PD1
LESSNER, HE1
HARRINGTON, WJ1
FRIEDMAN, OM1
BOGER, E1
GRUBLIAUSKAS, V1
SOMMER, H1
GREEN, RA1
DIXON, H1
MORROW, LB1
ANDERSON, RE1
VESIN, S1
LIBANSKY, J1
CHUDOMEL, V1
BRABEC, V1
SOCHMAN, J1
SANDOR, L1
CERNY, V1
UJHAZY, V1
WINKLER, A1
RUNDLES, W1
GRIZZLE, J1
BONO, VH1
JONSSON, U1
HUGULEY, CM2
CORLEY, CC1
KIELER, J1
Shohat, B1
Gitter, S1
Lavie, D1
Valeriote, F1
Grates, HE1
Krikler, SH1
Bain, GO1
Gordon, PA1
Pasqualini, T1
Foldesh, J1
Djaldetti, M1
Maurice, PA1
Lederrey, C1
Grant, MD1
Coleman, M1
Goldenberg, GJ3
Brody, JI1
Stefani, SS1
Lowenthal, RM1
Jestrimski, KW1
Zandecki, M1
Dupriez, B1
Laï, JL1
Fenaux, P1
Facon, T1
Lepelley, P1
Estienne, MH1
Huart, JJ1
Jouet, JP1
de Gramont, A1
Louvet, C1
Krulik, M1
Smadja, N1
Donadio, D1
Laporte, JP1
Brissaud, P1
Delâge, JM1
Drolet, Y1
Rioux, E1
Musto, P1
Lucchi, T1
Barbieri, D1
Ferraresi, P1
Lanza, F1
Martínez-Poventud, G1
Fradera, J1
Cintrón-López, J1
Vélez-García, E1
Moe, PJ1
Frei, E2
Fox, M1
Fox, BW1
Makino, F1
Okada, S1
Humphrey, GB1
Nesbit, ME1
Chary, KK1
Krivit, W1
Schabel, FM1
Goldin, A1
Miller, DR1
Sonley, M1
Karon, M1
Breslow, N1
Hammond, D1
Wodinsky, I1
Swiniarski, J1
Kensler, CJ1
Venditti, JM1
Benckhuijsen, C1
Cook, ES1
Nutini, LG1
Hazlett, LD1
Fairley, GH1
Silber, R1
Unger, KW1
Ellman, L1
Bruneau, R1
Rubin, P1
Hotchkiss, DJ1
Lewis, FB1
Schwartz, RS1
Dameshek, W1

Reviews

5 reviews available for mechlorethamine and Leukemia, Lymphocytic

ArticleYear
Treatment of chronic lymphocytic leukemia.
    Cancer treatment reviews, 1977, Volume: 4, Issue:4

    Topics: Adrenal Cortex Hormones; Alkylating Agents; Chlorambucil; Cyclophosphamide; Drug Therapy, Combinatio

1977
Corticosteroid drugs: their role in oncological practice.
    The Medical journal of Australia, 1986, Jan-20, Volume: 144, Issue:2

    Topics: Adrenal Cortex Hormones; Animals; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Breast

1986
[Acute lymphoblastic leukemia, Burkitt-cell type, after Hodgkin's disease. Study of 2 cases].
    Nouvelle revue francaise d'hematologie, 1987, Volume: 29, Issue:6

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Hodgkin Disease; H

1987
Chemotherapy and the life cycle of leukaemic cells. A comparison between the growth characteristics of human acute leukaemia and the murine leukaemia L 1210.
    Folia medica Neerlandica, 1969, Dec-02, Volume: 12, Issue:2

    Topics: Anilides; Animals; Cell Division; Cyclophosphamide; Cytarabine; DNA, Neoplasm; Fluorouracil; Humans;

1969
Combination chemotherapy in malignant diseases.
    Journal of the Royal College of Physicians of London, 1971, Volume: 5, Issue:2

    Topics: Adult; Antineoplastic Agents; Asparaginase; Carmustine; Child; Cyclophosphamide; Cytarabine; Cytosin

1971

Other Studies

56 other studies available for mechlorethamine and Leukemia, Lymphocytic

ArticleYear
[Nitrogen mustard therapy of proliferative blood diseases; methods, experiences as well as application possibilities in therapy of carcinoma].
    Wiener medizinische Wochenschrift (1946), 1953, Jan-03, Volume: 103, Issue:1

    Topics: Hematologic Diseases; Hodgkin Disease; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid; Lymp

1953
[Trials of treatment by p-(di-2-chloroethylamino)phenylbutyric acid in Hodgkin's disease, chronic lymphoid leukemia and different sarcomas of lymphatic tissue; study of one hundred cases].
    Revue francaise d'etudes cliniques et biologiques, 1956, Volume: 1, Issue:10

    Topics: Hodgkin Disease; Leukemia; Leukemia, Lymphocytic, Chronic, B-Cell; Leukemia, Lymphoid; Lymphoid Tiss

1956
Clinical experience with CB 1348 (NN-di(2-chloroethyl, -P-aminophenylbutyric acid) in the treatment of chronic lymphatic leukaemia.
    Acta radiologica, 1957, Volume: 47, Issue:3

    Topics: Chlorambucil; Leukemia; Leukemia, Lymphocytic, Chronic, B-Cell; Leukemia, Lymphoid; Mechlorethamine;

1957
[Treatment of Hodgkin's disease, chronic lymphoid leukosis and various lymphosarcomas with p-(di-2-chloroethyl) aminophenylbutyric acid].
    Le Sang, 1957, Volume: 28, Issue:1

    Topics: Hodgkin Disease; Leukemia; Leukemia, Lymphoid; Lymphoma; Lymphoma, Non-Hodgkin; Mechlorethamine; Nit

1957
[Severe terminal purpura during CB 1348 therapy of chronic lymphoid leukemia].
    Revue medicale de Nancy, 1957, Volume: 82

    Topics: Chlorambucil; Leukemia; Leukemia, Lymphocytic, Chronic, B-Cell; Leukemia, Lymphoid; Mechlorethamine;

1957
[Therapy of malignant diseases of the lymphatic and reticular systems with a nitrogen mustard derivative].
    Arzneimittel-Forschung, 1958, Volume: 8, Issue:6

    Topics: Hodgkin Disease; Leukemia; Leukemia, Lymphoid; Mannitol; Mechlorethamine; Neoplasms; Nitrogen Mustar

1958
Variability of the in vitro sensitivity of human leukemic lymphocytes to x-rays and chemotherapeutic agents.
    Journal of the National Cancer Institute, 1958, Volume: 20, Issue:6

    Topics: Humans; In Vitro Techniques; Leukemia; Leukemia, Lymphoid; Lymphocytes; Mechlorethamine; Nitrogen Mu

1958
[Lymphoid leukemia treated by the combination of cortisone, CB 1348 & transfusions].
    Journal de medecine de Bordeaux et du Sud-Ouest, 1958, Volume: 135, Issue:12

    Topics: Blood Transfusion; Chlorambucil; Cortisone; Leukemia; Leukemia, Lymphoid; Mechlorethamine; Nitrogen

1958
[Observations on the application of CB-1348 in lymphatic leukemias].
    Polskie Archiwum Medycyny Wewnetrznej, 1959, Volume: 29, Issue:3

    Topics: Chlorambucil; Humans; Leukemia; Leukemia, Lymphoid; Mechlorethamine; Nitrogen Mustard Compounds

1959
Effects of nitrogen mustard on the histochemistry of mouse lymphocytic leukaemia L 1210.
    Nature, 1961, Feb-18, Volume: 189

    Topics: Animals; Leukemia L1210; Leukemia, Experimental; Leukemia, Lymphoid; Lymphocytes; Mechlorethamine; M

1961
The use of chlorambucil and steroids in the treatment of chronic lymphocytic leukaemia.
    British journal of haematology, 1961, Volume: 7

    Topics: Adrenal Cortex Hormones; Chlorambucil; Humans; Leukemia; Leukemia, Lymphocytic, Chronic, B-Cell; Leu

1961
Evaluation of the effectiveness of radioactive phosphorus and chlorambucil in patients with chronic lymphocytic leukemia.
    Cancer chemotherapy reports, 1962, Volume: 16

    Topics: Chlorambucil; Leukemia; Leukemia, Lymphocytic, Chronic, B-Cell; Leukemia, Lymphoid; Lymphocytes; Mec

1962
Effect of uracil mustard in malignant lymphoma and chronic lymphatic leukemia.
    Minnesota medicine, 1962, Volume: 45

    Topics: Leukemia; Leukemia, Lymphoid; Lymphoma; Mechlorethamine; Minnesota; Nitrogen Mustard Compounds; Urac

1962
[Forms of leukosis and their therapy].
    Therapeutische Umschau. Revue therapeutique, 1963, Volume: 20

    Topics: Adrenocorticotropic Hormone; Antineoplastic Agents; Busulfan; Colchicine; Folic Acid Antagonists; Go

1963
LEUKEMIA. AN ANALYSIS OF 209 CASES FROM THE ELLIS FISCHEL STATE CANCER HOSPITAL.
    Missouri medicine, 1963, Volume: 60

    Topics: Adrenal Cortex Hormones; Anti-Bacterial Agents; Antineoplastic Agents; Busulfan; Cancer Care Facilit

1963
RESISTANCE OF PHYTOHAEMAGGLUTININ-TREATED LYMPHOCYTES TO X-RAYS AND NITROGEN MUSTARD.
    Nature, 1963, Nov-02, Volume: 200

    Topics: Antibodies; Biochemical Phenomena; Humans; Leukemia; Leukemia, Lymphoid; Lymphocytes; Mechlorethamin

1963
CHRONIC LYMPHATIC LEUKAEMIA AND ITS MANAGEMENT.
    The New Zealand medical journal, 1963, Volume: 62

    Topics: Adrenal Cortex Hormones; Chlorambucil; Geriatrics; Humans; Leukemia; Leukemia, Lymphoid; Mechloretha

1963
EXCRETION OF TRYPTOPHAN METABOLITES IN DIFFERENT FORMS OF HAEMOBLASTOSIS.
    Clinica chimica acta; international journal of clinical chemistry, 1964, Volume: 9

    Topics: Cortisone; Cyclophosphamide; Genetic Diseases, X-Linked; Hodgkin Disease; Humans; Kynurenic Acid; Ky

1964
WEEKLY HIGH-DOSAGE GLUCOCORTICOSTEROID TREATMENT OF LYMPHOCYTIC LEUKEMIAS AND LYMPHOMAS.
    The New England journal of medicine, 1964, May-28, Volume: 270

    Topics: Anemia; Anemia, Hemolytic; Betamethasone; Chlorambucil; Dexamethasone; Geriatrics; Humans; Leukemia;

1964
SYNTHESIS OF N-PHOSPHORYLATED DERIVATIVES OF NITROGEN MUSTARDS WITH LATENT CYTOTOXICITY.
    Journal of medicinal chemistry, 1963, Volume: 6

    Topics: Animals; Chemistry, Pharmaceutical; Leukemia; Leukemia L1210; Leukemia, Experimental; Leukemia, Lymp

1963
EXPECTANCY FOR LIFE IN CHRONIC LYMPHATIC LEUKEMIA.
    Blood, 1965, Volume: 25

    Topics: Adrenal Cortex Hormones; Alkylating Agents; Antineoplastic Agents; Child; Chlorambucil; Cyclophospha

1965
ACTIVE TUBERCULOSIS IN LEUKEMIA. MALIGNANT LYMPHOMA AND MYELOFIBROSIS.
    Archives of pathology, 1965, Volume: 79

    Topics: Alkylating Agents; Aminopterin; Busulfan; Hodgkin Disease; Humans; Leukemia; Leukemia, Lymphoid; Leu

1965
[Combination of microdosage of chloralkylamines with roentgen irradiation in the treatment of hemoblastoses and hemoblastomas].
    Casopis lekaru ceskych, 1952, Nov-14, Volume: 91, Issue:45-46

    Topics: Hodgkin Disease; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid; Lymphatic Vessels; Mechlorethamine

1952
Treatment of malignant lymphomas and lymphadenoses with leukeran.
    Neoplasma, 1959, Volume: 6

    Topics: Chlorambucil; Hodgkin Disease; Leukemia; Leukemia, Lymphoid; Lymphoma; Mechlorethamine; Nitrogen Mus

1959
Clinical evaluation of the effect of degranol.
    Neoplasma, 1959, Volume: 6

    Topics: Hodgkin Disease; Leukemia; Leukemia, Lymphoid; Lymphocytes; Mannitol; Mannomustine; Mechlorethamine;

1959
Comparison of CB-1348 (chlorambucil, leukeran) and CB-1364.
    Cancer chemotherapy reports, 1962, Volume: 16

    Topics: Antineoplastic Agents; Chlorambucil; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid; Mechlo

1962
Nitrogen mustard therapy in Hodgkin's disease, lympho-reticulosarcomatosis and lymphatic leukaemia.
    Acta radiologica, 1951, Volume: 36, Issue:6

    Topics: Hodgkin Disease; Leukemia; Leukemia, Lymphoid; Lymphoma; Lymphoma, Non-Hodgkin; Mechlorethamine; Nit

1951
Action of elatericin A on human leukemic and normal lymphocytes.
    Journal of the National Cancer Institute, 1967, Volume: 38, Issue:1

    Topics: Aminopterin; Animals; Antineoplastic Agents; Azirines; Cathartics; Cell Nucleus; Chlorambucil; Cyclo

1967
Dose and interval relationship for the interaction of WR-2721 and nitrogen mustard with normal and malignant cells.
    International journal of radiation oncology, biology, physics, 1984, Volume: 10, Issue:9

    Topics: Amifostine; Animals; Dose-Response Relationship, Drug; Drug Synergism; Female; Hematopoietic Stem Ce

1984
Burkitt cell leukemia following treatment of Hodgkin's disease: report of a case and review of the literature.
    American journal of hematology, 1984, Volume: 17, Issue:2

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; B-Lymphocytes; Hodgkin Disease; Humans; Leuke

1984
[Testicular damage caused by chemotherapy in acute lymphoblastic leukemia].
    Medicina, 1983, Volume: 43, Issue:5

    Topics: Adolescent; Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Child; C

1983
[The effect of alkylating agents on DNA, RNA and protein synthesis by leukemic lymphocytes in vitro].
    Harefuah, 1979, Feb-01, Volume: 96, Issue:3

    Topics: Blood Proteins; Cyclophosphamide; DNA; Humans; Leukemia, Lymphoid; Lymphocytes; Mechlorethamine; RNA

1979
Increased sensitivity of chronic lymphocytic leukemia lymphocytes to alkylating agents due to a deficient DNA repair mechanism.
    European journal of cancer, 1977, Volume: 13, Issue:9

    Topics: DNA Repair; DNA, Neoplasm; Dose-Response Relationship, Drug; Humans; Hypersensitivity, Delayed; Leuk

1977
Hodgkin disease with acute lymphoblastic leukemia.
    JAMA, 1975, Feb-10, Volume: 231, Issue:6

    Topics: Acute Disease; Adolescent; Daunorubicin; Drug Therapy, Combination; Hodgkin Disease; Humans; Leukemi

1975
The role of drug transport in resistance to nitrogen mustard and other alkylating agents in L518Y lymphoblsts.
    Cancer research, 1975, Volume: 35, Issue:7

    Topics: Alkylating Agents; Animals; Binding, Competitive; Biological Transport; Carmustine; Cell Line; Chlor

1975
Drug-induced stimulation of transport of hydrolyzed nitrogen mustard and choline by normal and leukemic human cells in vitro.
    Cancer research, 1976, Volume: 36, Issue:3

    Topics: Biological Transport; Choline; Cocaine; Dose-Response Relationship, Drug; In Vitro Techniques; Leuke

1976
Differential uptake of alkylating agents by normal and leukemic lymphocytes.
    Cancer, 1975, Volume: 36, Issue:6

    Topics: Adult; Aged; Alkylating Agents; B-Lymphocytes; Cyclophosphamide; Cytotoxicity Tests, Immunologic; Fl

1975
Cytarabine: cytocidal effect on normal and leukemic lymphocytes. Synergism with x rays and comparison with mechlorethamine.
    Experimental and molecular pathology, 1976, Volume: 24, Issue:1

    Topics: Cytarabine; Deoxycytidine; Humans; Leukemia, Lymphoid; Lymphocytes; Mechlorethamine; Radiation Effec

1976
Erythrocyte mean corpuscular volume during cytotoxic therapy is a predictive parameter of secondary leukemia in Hodgkin's disease.
    Cancer, 1987, Jan-15, Volume: 59, Issue:2

    Topics: Antineoplastic Combined Chemotherapy Protocols; Erythrocyte Indices; Hodgkin Disease; Humans; Leukem

1987
[Acute lymphoblastic leukemia L3 in Hodgkin's disease in remission: primary or secondary leukosis?].
    Recenti progressi in medicina, 1985, Volume: 76, Issue:4

    Topics: Antineoplastic Combined Chemotherapy Protocols; Hodgkin Disease; Humans; Karyotyping; Leukemia, Lymp

1985
Chronic lymphocytic leukemia: a study of 53 patients and review of the literature.
    Boletin de la Asociacion Medica de Puerto Rico, 1985, Volume: 77, Issue:11

    Topics: Adult; Age Factors; Aged; Antineoplastic Combined Chemotherapy Protocols; Chlorambucil; Combined Mod

1985
Varicella in immunodepressed children.
    Postgraduate medical journal, 1985, Volume: 61 Suppl 4

    Topics: Antineoplastic Combined Chemotherapy Protocols; Chickenpox; Child; Female; Hodgkin Disease; Humans;

1985
Current status and new vistas in combination chemotherapy.
    The Mount Sinai journal of medicine, New York, 1985, Volume: 52, Issue:6

    Topics: Antineoplastic Combined Chemotherapy Protocols; Child; Combined Modality Therapy; Hodgkin Disease; H

1985
Repair replication and unscheduled DNA synthesis in mammalian cell lines showing differential sensitivity to alkylating agents.
    Mutation research, 1973, Volume: 19, Issue:1

    Topics: Alkylating Agents; Animals; Autoradiography; Cell Line; Cell Survival; Centrifugation, Density Gradi

1973
Comparative studies of the effects of carcinogenic and antitumor agents on the DNA replication of cultured mammalian cells.
    Mutation research, 1974, Volume: 23, Issue:3

    Topics: Animals; Antineoplastic Agents; Carcinogens; Cell Line; Cells, Cultured; Centrifugation, Zonal; DNA

1974
Impaired lymphocyte transformation in leukemic patients after intensive therapy.
    Cancer, 1972, Volume: 29, Issue:2

    Topics: Adolescent; Antineoplastic Agents; Child; Child, Preschool; Cobalt Isotopes; Cytarabine; Female; Hum

1972
Comparative chemotherapy of AKR lymphoma and human hematological neoplasia.
    Cancer research, 1974, Volume: 34, Issue:1

    Topics: Animals; Antineoplastic Agents; Biological Assay; Carmustine; Cyclohexanes; Cyclophosphamide; Cytara

1974
Additive therapy in the maintenance of remission in acute lymphoblastic leukemia of childhood: the effect of the initial leukocyte count.
    Cancer, 1974, Volume: 34, Issue:3

    Topics: Adolescent; Age Factors; Blood; Brain Neoplasms; Child; Child, Preschool; Dactinomycin; Digestive Sy

1974
Drug-induced stimulation of nitrogen mustard and choline transport and other systems in L5178Y lymphoblasts in vitro.
    Cancer research, 1974, Volume: 34, Issue:10

    Topics: Amino Acids; Aminoisobutyric Acids; Aminolevulinic Acid; Animals; Atropine; Biological Transport; Ce

1974
Combination radiotherapy and chemotherapy for P388 lymphocytic leukemia in vivo.
    Cancer chemotherapy reports. Part 2, 1974, Volume: 4, Issue:1

    Topics: Alanine; Animals; Cisplatin; Cobalt Radioisotopes; Cyclophosphamide; Cytarabine; Female; Fluorouraci

1974
Counteraction of leukopenia caused by mechlorethamine and azathioprine.
    Journal of surgical oncology, 1971, Volume: 3, Issue:2

    Topics: Animals; Antineoplastic Agents; Azathioprine; Dogs; Erythrocyte Count; Female; Kidney Transplantatio

1971
Short-term effects of actinomycin D and nitrogen mustard on murine lymphocytic leukemia P388.
    Journal of the National Cancer Institute, 1971, Volume: 47, Issue:6

    Topics: Animals; Cell Nucleolus; Dactinomycin; Depression, Chemical; Glucosephosphate Dehydrogenase; Histocy

1971
RNA metabolism in normal and leukaemic leucocytes: further studies on RNA synthesis.
    British journal of haematology, 1968, Volume: 14, Issue:3

    Topics: Antimetabolites; Busulfan; Carbon Isotopes; Chromatography; Humans; Leukemia; Leukemia, Lymphoid; Le

1968
The management of pleural effusions and chylothorax in lymphoma.
    Radiology, 1965, Volume: 85, Issue:6

    Topics: Adult; Chylothorax; Exudates and Transudates; Female; Humans; Leukemia, Lymphoid; Lymphoma, Large B-

1965
Hemolytic anemia and thrombocytopenia (ITP type) in chronic lymphocytic leukemia following nitrogen mustard therapy.
    Cancer, 1966, Volume: 19, Issue:6

    Topics: Aged; Anemia, Hemolytic, Autoimmune; Blood Platelet Disorders; Bone Marrow Cells; Hemoglobinometry;

1966
X-radiation and alkylating agents as possible "trigger" mechanisms in the autoimmune complications of malignant lymphophroliferative disease.
    Clinical and experimental immunology, 1966, Volume: 1, Issue:1

    Topics: Adult; Aged; Anemia, Hemolytic, Autoimmune; Chlorambucil; Humans; Leukemia, Lymphoid; Lymphoma, Non-

1966