mechlorethamine has been researched along with Kidney Failure, Chronic in 3 studies
nitrogen mustard : Compounds having two beta-haloalkyl groups bound to a nitrogen atom, as in (X-CH2-CH2)2NR.
Kidney Failure, Chronic: The end-stage of CHRONIC RENAL INSUFFICIENCY. It is characterized by the severe irreversible kidney damage (as measured by the level of PROTEINURIA) and the reduction in GLOMERULAR FILTRATION RATE to less than 15 ml per min (Kidney Foundation: Kidney Disease Outcome Quality Initiative, 2002). These patients generally require HEMODIALYSIS or KIDNEY TRANSPLANTATION.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Twenty-two patients with histologically demonstrated diffuse proliferative lupus nephritis (DPLN) and glomerular thrombosis received a 14-day course of ancrod, followed in most by nitrogen mustard (mechlorethamine hydrochloride) 0." | 3.68 | Diffuse proliferative lupus nephritis: long-term observations in patients treated with ancrod. ( Hariharan, S; Kant, KS; Pollak, VE; Wadhwa, NK; Weiss, MA, 1990) |
| "Risk of ESRD by WHO class at 5 years was as follows: class III, 0%; IV, 9%; V, 16% (P = ." | 1.29 | Lupus in the 1980s: III. Influence of clinical variables, biopsy, and treatment on the outcome in 150 patients with lupus nephritis seen at a single center. ( Azen, C; Fichman, M; Klinenberg, JR; Metzger, AL; Nessim, S; Neumann, K; Wallace, DJ, 1995) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (33.33) | 18.7374 |
| 1990's | 2 (66.67) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Neumann, K | 1 |
| Wallace, DJ | 1 |
| Azen, C | 1 |
| Nessim, S | 1 |
| Fichman, M | 1 |
| Metzger, AL | 1 |
| Klinenberg, JR | 1 |
| Hariharan, S | 1 |
| Pollak, VE | 1 |
| Kant, KS | 1 |
| Weiss, MA | 1 |
| Wadhwa, NK | 1 |
| Ultmann, JE | 1 |
| Nixon, DD | 1 |
1 review available for mechlorethamine and Kidney Failure, Chronic
| Article | Year |
|---|---|
The therapy of lymphoma.
Topics: Adrenal Cortex Hormones; Asparaginase; Bone Marrow Diseases; Chlorambucil; Cyclophosphamide; Cytarab | 1969 |
2 other studies available for mechlorethamine and Kidney Failure, Chronic
| Article | Year |
|---|---|
Lupus in the 1980s: III. Influence of clinical variables, biopsy, and treatment on the outcome in 150 patients with lupus nephritis seen at a single center.
Topics: Adult; Anti-Inflammatory Agents; Azathioprine; Biopsy; Blood Component Removal; Chlorambucil; Cyclop | 1995 |
Diffuse proliferative lupus nephritis: long-term observations in patients treated with ancrod.
Topics: Adult; Ancrod; Blood Pressure; Creatinine; Drug Therapy, Combination; Female; Follow-Up Studies; Hum | 1990 |