mechlorethamine has been researched along with Keratoacanthoma in 2 studies
nitrogen mustard : Compounds having two beta-haloalkyl groups bound to a nitrogen atom, as in (X-CH2-CH2)2NR.
Keratoacanthoma: A benign, non-neoplastic, usually self-limiting epithelial lesion closely resembling squamous cell carcinoma clinically and histopathologically. It occurs in solitary, multiple, and eruptive forms. The solitary and multiple forms occur on sunlight exposed areas and are identical histologically; they affect primarily white males. The eruptive form usually involves both sexes and appears as a generalized papular eruption.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Despite the dramatic response of Hodgkin's disease to intensive chemotherapy, the skin lesion was rapidly transformed into squamous cell carcinoma in 10 weeks." | 1.26 | Rapid development of keratoacanthoma and accelerated transformation into squamous cell carcinoma of the skin: a mutagenic effect of polychemotherapy in a patient with Hodgkin's disease? ( Poleksic, S; Yeung, KY, 1978) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kopf, AW | 1 |
| Bart, RS | 1 |
| Poleksic, S | 1 |
| Yeung, KY | 1 |
2 other studies available for mechlorethamine and Keratoacanthoma
| Article | Year |
|---|---|
Development of more keratoacanthomas following skin testing with nitrogen mustard in a patient with the multiple keratoacanthoma syndrome.
Topics: Adult; Drug Hypersensitivity; Humans; Keratoacanthoma; Male; Mechlorethamine; Skin Tests; Time Facto | 1979 |
Rapid development of keratoacanthoma and accelerated transformation into squamous cell carcinoma of the skin: a mutagenic effect of polychemotherapy in a patient with Hodgkin's disease?
Topics: Antineoplastic Agents; Carcinoma, Squamous Cell; Drug Therapy, Combination; Hodgkin Disease; Humans; | 1978 |