Page last updated: 2024-10-30

mechlorethamine and Ischemia

mechlorethamine has been researched along with Ischemia in 3 studies

nitrogen mustard : Compounds having two beta-haloalkyl groups bound to a nitrogen atom, as in (X-CH2-CH2)2NR.

Ischemia: A hypoperfusion of the BLOOD through an organ or tissue caused by a PATHOLOGIC CONSTRICTION or obstruction of its BLOOD VESSELS, or an absence of BLOOD CIRCULATION.

Research Excerpts

ExcerptRelevanceReference
"Hind limb ischemia and reperfusion have been shown to result in high plasma levels of leukotriene B4 (LTB4) and polymorphonuclear neutrophil (PMN) sequestration in the pulmonary microvasculature."7.68Oxygen free radicals are required for ischemia-induced leukotriene B4 synthesis and diapedesis. ( Goldman, G; Hechtman, HB; Klausner, JM; Shepro, D; Valeri, CR; Welbourn, R, 1992)
"Hind limb ischemia and reperfusion have been shown to result in high plasma levels of leukotriene B4 (LTB4) and polymorphonuclear neutrophil (PMN) sequestration in the pulmonary microvasculature."3.68Oxygen free radicals are required for ischemia-induced leukotriene B4 synthesis and diapedesis. ( Goldman, G; Hechtman, HB; Klausner, JM; Shepro, D; Valeri, CR; Welbourn, R, 1992)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19902 (66.67)18.7374
1990's1 (33.33)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
ALEXANDER, JW1
ALTEMEIER, WA1
Jampol, LM1
Noth, J1
Goldman, G1
Welbourn, R1
Klausner, JM1
Valeri, CR1
Shepro, D1
Hechtman, HB1

Other Studies

3 other studies available for mechlorethamine and Ischemia

ArticleYear
SUSCEPTIBILITY OF INJURED TISSUES TO HEMATOGENOUS METASTASES: AN EXPERIMENTAL STUDY.
    Annals of surgery, 1964, Volume: 159

    Topics: Abdominal Wall; Chemotherapy, Cancer, Regional Perfusion; Dextrans; Disease Susceptibility; Ischemia

1964
Further studies of the ipsilateral and contralateral responses to topical nitrogen mustard.
    Experimental eye research, 1979, Volume: 28, Issue:5

    Topics: Administration, Topical; Animals; Aqueous Humor; Eye; Eye Proteins; Iris; Ischemia; Male; Mechloreth

1979
Oxygen free radicals are required for ischemia-induced leukotriene B4 synthesis and diapedesis.
    Surgery, 1992, Volume: 111, Issue:3

    Topics: Allopurinol; Animals; Chemotaxis, Leukocyte; Chromones; Free Radicals; Hindlimb; Ischemia; Leukotrie

1992