mechlorethamine has been researched along with Intraocular Pressure in 14 studies
nitrogen mustard : Compounds having two beta-haloalkyl groups bound to a nitrogen atom, as in (X-CH2-CH2)2NR.
Intraocular Pressure: The pressure of the fluids in the eye.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Application of nitrogen mustard to the eye of rabbits causes an anterior segment irritation and a biphasic elevation of intraocular pressure." | 3.69 | Influence of diltiazem on the ocular irritative response to nitrogen mustard. ( Belmonte, C; Gallar, J; Gonzalez, GG, 1995) |
| "The effect of intraperitoneal injections of dipyridamole on the elevations of intraocular pressure and anterior chamber aqueous humor protein produced by topical application of prostaglandin E2 was studied in rabbits." | 3.66 | Effect of dipyridamole on prostaglandin-induced ocular hypertension in rabbits. ( Podos, SM, 1979) |
| "In the DRS-treated group, the corneal opacity and corneal neovascularization were less severe, and development of iris atrophy was delayed." | 1.39 | Use of amphoteric rinsing solution for treatment of ocular tissues exposed to nitrogen mustard. ( Avni, I; Barkana, Y; Berenshtein, E; Chevion, M; Goldich, Y; Rosner, M; Zadok, D, 2013) |
| "Colchicine pretreatment also inhibited the ocular hypertensive response to topically administered formaldehyde." | 1.27 | Inhibition of the acute ocular responses to nitrogen mustard by colchicine. ( Bhattacherjee, P; Williams, RN, 1984) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 10 (71.43) | 18.7374 |
| 1990's | 1 (7.14) | 18.2507 |
| 2000's | 2 (14.29) | 29.6817 |
| 2010's | 1 (7.14) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Goldich, Y | 1 |
| Barkana, Y | 1 |
| Zadok, D | 1 |
| Avni, I | 1 |
| Berenshtein, E | 3 |
| Rosner, M | 1 |
| Chevion, M | 3 |
| Banin, E | 2 |
| Morad, Y | 2 |
| Obolensky, A | 2 |
| Yahalom, C | 1 |
| Goldich, J | 1 |
| Adibelli, FM | 1 |
| Zuniga, G | 1 |
| DeAnda, M | 1 |
| Pe'er, J | 1 |
| DAVSON, H | 1 |
| HUBER, A | 1 |
| Averbukh, E | 1 |
| Cole, DF | 1 |
| Camras, CB | 2 |
| Bito, LZ | 4 |
| Williams, RN | 1 |
| Bhattacherjee, P | 1 |
| Klein, EM | 1 |
| Gonzalez, GG | 1 |
| Gallar, J | 1 |
| Belmonte, C | 1 |
| Eakins, KE | 1 |
| Podos, SM | 1 |
| Maul, E | 1 |
| Sears, ML | 1 |
2 reviews available for mechlorethamine and Intraocular Pressure
| Article | Year |
|---|---|
Species differences in the responses of the eye to irritation and trauma: a hypothesis of divergence in ocular defense mechanisms, and the choice of experimental animals for eye research.
Topics: Aging; Animals; Anterior Chamber; Aotus trivirgatus; Aqueous Humor; Biological Evolution; Blood; Cat | 1984 |
Prostaglandin and non-prostaglandin mediated breeakdown of the blood-aqueous barrier.
Topics: Animals; Aqueous Humor; Aspirin; Blood; Capillary Permeability; Eye; Humans; Indomethacin; Intraocul | 1977 |
12 other studies available for mechlorethamine and Intraocular Pressure
| Article | Year |
|---|---|
Use of amphoteric rinsing solution for treatment of ocular tissues exposed to nitrogen mustard.
Topics: Animals; Atrophy; Burns, Chemical; Chemical Warfare Agents; Corneal Diseases; Corneal Neovasculariza | 2013 |
Injury induced by chemical warfare agents: characterization and treatment of ocular tissues exposed to nitrogen mustard.
Topics: Administration, Topical; Animals; Anterior Eye Segment; Burns, Chemical; Chemical Warfare Agents; De | 2003 |
Effects of nitrogen mustard on the intraocular pressure.
Topics: Eye; Eye Diseases; Intraocular Pressure; Mechlorethamine; Nitrogen Mustard Compounds; Tonometry, Ocu | 1950 |
Treatment of ocular tissues exposed to nitrogen mustard: beneficial effect of zinc desferrioxamine combined with steroids.
Topics: Animals; Atrophy; Burns, Chemical; Chemical Warfare Agents; Corneal Diseases; Corneal Neovasculariza | 2005 |
PREVENTION OF EXPERIMENTAL OCULAR HYPERTENSION WITH POLYPHLORETIN PHOSPHATE.
Topics: Alkylating Agents; Animals; Aqueous Humor; Blood Pressure; Disease Models, Animal; Eye Proteins; Int | 1961 |
The pathophysiological effects of nitrogen mustard on the rabbit eye. II. The inhibition of the initial hypertensive phase by capsaicin and the apparent role of substance P.
Topics: Animals; Capsaicin; Denervation; Ethanol; Eye; Fatty Acids, Unsaturated; Indomethacin; Intraocular P | 1980 |
Inhibition of the acute ocular responses to nitrogen mustard by colchicine.
Topics: Animals; Aqueous Humor; Colchicine; Dose-Response Relationship, Drug; Endophthalmitis; Eye; Eye Prot | 1984 |
Species variations in the pathophysiologic responses of vertebrate eyes to a chemical irritant, nitrogen mustard.
Topics: Animals; Anterior Chamber; Aotus trivirgatus; Cats; Ducks; Eye; Guinea Pigs; Indomethacin; Intraocul | 1983 |
The pathophysiological effects of nitrogen mustard on the rabbit eye. I. The biphasic intraocular pressure response and the role of prostaglandins.
Topics: Animals; Aqueous Humor; Cornea; Ethanol; Indomethacin; Intraocular Pressure; Leukocyte Count; Mechlo | 1980 |
Influence of diltiazem on the ocular irritative response to nitrogen mustard.
Topics: Administration, Topical; Animals; Diltiazem; Endophthalmitis; Eye; Injections, Intravenous; Intraocu | 1995 |
Effect of dipyridamole on prostaglandin-induced ocular hypertension in rabbits.
Topics: Administration, Topical; Animals; Aqueous Humor; Dipyridamole; Eye Proteins; Injections, Intraperito | 1979 |
Objective evaluation of experimental ocular irritation.
Topics: Animals; Aqueous Humor; Conjunctiva; Constriction; Eye; Eye Diseases; Hyperemia; Intraocular Pressur | 1976 |