Page last updated: 2024-10-30

mechlorethamine and Injuries, Radiation

mechlorethamine has been researched along with Injuries, Radiation in 27 studies

nitrogen mustard : Compounds having two beta-haloalkyl groups bound to a nitrogen atom, as in (X-CH2-CH2)2NR.

Research Excerpts

ExcerptRelevanceReference
"The majority of patients with Hodgkin's disease can be cured by combination of polychemotherapy and radiotherapy (RT) that can produce late toxic pulmonary and cardiac effects which often remain at a subclinical level."1.36Cardiopulmonary toxicity of different chemoradiotherapy combined regimens for Hodgkin's disease. ( Bonfante, V; Busia, A; Laffranchi, A; Villani, F; Viviani, S, 2010)
"Therefore, 126 patients suffering from Hodgkin's disease were investigated after a follow-up of at least 5 years from the completion of the combined treatment."1.35Cardiopulmonary response to exercise in patients with different degrees of lung toxicity after radio-chemotherapy for Hodgkin's disease. ( Bonfante, V; Busia, A; Laffranchi, A; Villani, F; Villani, M; Viviani, S, 2009)
" There were three fatal toxic events, two due to viral infection and one to a second malignant tumor (NHL)."1.28Hodgkin's disease in children: treatment with MOPP and low-dose, extended field irradiation without laparotomy. Late results and toxicity. ( Berry, M; Blanchette, V; Chan, H; Doherty, M; Doyle, J; Freedman, M; Greenberg, M; Jenkin, D; Panzarella, T; Saunders, F, 1990)
"A 27 year old man with Hodgkin's disease experienced three separate episodes of chest pain, each occurring on the sixth day of a cycle of mustargen, oncovin, procarbazine, prednisone (MOPP) combination chermotherapy."1.26Unusual cardiac reaction to chemotherapy following mediastinal irradiation in a patient with Hodgkin's disease. ( Greenwald, ES; Grossman, J; Weinstein, P, 1976)

Research

Studies (27)

TimeframeStudies, this research(%)All Research%
pre-199021 (77.78)18.7374
1990's3 (11.11)18.2507
2000's1 (3.70)29.6817
2010's2 (7.41)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Villani, F2
Busia, A2
Villani, M1
Laffranchi, A2
Viviani, S2
Bonfante, V2
Schlienger, M1
Ferroir, JP1
Huguet, F1
Deluen, F1
Pène, F1
Marseguerra, R1
Touboul, E1
HEIDELMANN, G1
ASANO, M1
ODELL, TT1
McDONALD, TP1
UPTON, AC2
FEINSTEIN, RN1
SEAHOLM, JE1
SMITH, JC2
KREPSZ, I1
PUPP, A1
GYERGYAY, F1
DICARLO, R1
PAGNINI, G1
FLIEDNER, TM1
THOMAS, ED1
MEYER, LM1
CRONKITE, EP1
JUSTIN-BESANCON, L1
GRIVAUX, M1
CORNET, A1
TOURNEUR, R1
GUERRE, J1
BOLANDE, RP1
CONKLIN, JW1
CHRISTENBERRY, KW1
ZWEIFACH, BW1
KIVY-ROSENBERG, E1
KIRCHMAIR, H1
Fuller, LM1
Gamble, JF1
Velazquez, WS1
Rodgers, RW1
Butler, JJ1
North, LB1
Martin, RG1
Gehan, EA1
Shullenberger, CC1
Aisenberg, AC1
Meyler, TS1
Blumberg, AL1
Purser, P1
Hellman, S2
Mauch, P1
Goodman, RL1
Rosenthal, DS2
Moloney, WC1
Weinstein, P1
Greenwald, ES1
Grossman, J1
Allavena, C1
Conroy, T1
Aletti, P1
Bey, P1
Lederlin, P1
Jenkin, D2
Doyle, J2
Berry, M1
Blanchette, V1
Chan, H1
Doherty, M1
Freedman, M1
Greenberg, M1
Panzarella, T1
Saunders, F1
Mauch, PM1
Canellos, GP1
Rosenberg, SA1
Kaplan, HS1
Ewing, DP1
McEwen, BW1
Atkinson, L1
Lewis, FB1
Schwartz, RS1
Dameshek, W1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Evaluation of Late Treatment Effects in Long-Term Survivors of Hodgkin's Disease Previously Treated at NIH: A Multi-Institutional Trial[NCT00924131]157 participants (Anticipated)Observational2009-04-17Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

2 reviews available for mechlorethamine and Injuries, Radiation

ArticleYear
[Dropped Head Syndrome after whiplash injury in a patient treated for a Hodgkin's lymphoma by mantle field radiotherapy].
    Cancer radiotherapie : journal de la Societe francaise de radiotherapie oncologique, 2013, Volume: 17, Issue:1

    Topics: Accidents, Traffic; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cervical Plexus; Cerv

2013
Problems in Hodgkin's disease management.
    Blood, 1999, Feb-01, Volume: 93, Issue:3

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Bone Marrow Transplant

1999

Trials

1 trial available for mechlorethamine and Injuries, Radiation

ArticleYear
The evolution and summary results of the Stanford randomized clinical trials of the management of Hodgkin's disease: 1962-1984.
    International journal of radiation oncology, biology, physics, 1985, Volume: 11, Issue:1

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Child; Clinical Trials as Topic; Combine

1985

Other Studies

24 other studies available for mechlorethamine and Injuries, Radiation

ArticleYear
Cardiopulmonary response to exercise in patients with different degrees of lung toxicity after radio-chemotherapy for Hodgkin's disease.
    Anticancer research, 2009, Volume: 29, Issue:2

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cardiovascular Diseases; Com

2009
Cardiopulmonary toxicity of different chemoradiotherapy combined regimens for Hodgkin's disease.
    Anticancer research, 2010, Volume: 30, Issue:10

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cardiovascular Diseases; Com

2010
[Clinical experience with an antihistamine-xanthine compound, used as antiemetic in roentgen intoxication and in nitrogen mustard therapy].
    Deutsche medizinische Wochenschrift (1946), 1952, Nov-14, Volume: 77, Issue:46

    Topics: Antiemetics; Histamine H1 Antagonists; Humans; Mechlorethamine; Nitrogen Mustard Compounds; Radiatio

1952
Radiomimetic agents and x-rays in mice and AET protectiveness. Comparative pathological effects.
    Archives of pathology, 1963, Volume: 75

    Topics: Animals; beta-Aminoethyl Isothiourea; Busulfan; Mechlorethamine; Mice; Protective Agents; Radiation

1963
EFFECT OF A SEROTONIN ANTAGONIST ON RADIATION LETHALITY.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1963, Volume: 114

    Topics: Animals; Mechlorethamine; Mice; Radiation Injuries; Radiation Injuries, Experimental; Radiation-Prot

1963
RADIATION PNEUMONITIS. CASE REPORT OF BILATERAL REACTION AFTER UNILATERNAL IRRADIATION.
    The American review of respiratory disease, 1964, Volume: 89

    Topics: Child; Lymphatic Metastasis; Lymphoma; Lymphoma, Non-Hodgkin; Mechlorethamine; Mediastinal Neoplasms

1964
[THE REDUCTION OF RADIOPHOSPHORUS 32 INCORPORATION INTO CANCER CELLS BY NONTOXIC DOSES OF CYTOSTATIC SUBSTANCES].
    Radiobiologia, radiotherapia, 1963, Volume: 4

    Topics: Animals; Carcinoma; Carcinoma, Ehrlich Tumor; Cyclophosphamide; Cytostatic Agents; Mannomustine; Mec

1963
[SULFUROUS MINERAL WATER AND METHYL-BIS-(2CHLORETHYL)-AMINE].
    Bollettino della Societa italiana di biologia sperimentale, 1963, Nov-30, Volume: 39

    Topics: Amines; Animals; Mechlorethamine; Mice; Mineral Waters; Pharmacology; Radiation Injuries; Radiation

1963
THE FATE OF TRANSFUSED H3 THYMIDINE-LABELED BONE-MARROW CELLS IN IRRADIATED RECIPIENTS.
    Annals of the New York Academy of Sciences, 1964, Mar-31, Volume: 114

    Topics: Animals; Biomedical Research; Bone Marrow; Bone Marrow Cells; Bone Marrow Transplantation; Dogs; Mec

1964
[RESEARCH ON CERTAIN DIGESTIVE DYSKINESIAS AND FUNCTIONAL DISORDERS].
    Bulletins et memoires de la Societe medicale des hopitaux de Paris, 1964, May-15, Volume: 115

    Topics: Antiemetics; Apomorphine; Cobalt Isotopes; Cyclophosphamide; Digitalis Glycosides; Dyskinesias; Dysp

1964
RADIATION AND DRUG INDUCED HYALINIZATION OF THE STOMACH.
    Archives of pathology, 1965, Volume: 79

    Topics: Antineoplastic Agents; Child; Chlorambucil; Cyclophosphamide; Drug Therapy; Ganglioneuroma; Gastroin

1965
FURTHER OBSERVATIONS ON LATE SOMATIC EFFECTS OF RADIOMIMETIC CHEMICALS AND X-RAYS IN MICE.
    Cancer research, 1965, Volume: 25

    Topics: Aging; Busulfan; Cataract; Female; Humans; Leukemia; Leukemia, Myeloid; Longevity; Lung Neoplasms; L

1965
MICROCIRCULATORY EFFECTS OF WHOLE-BODY X-IRRADIATION AND RADIOMIMETIC PROCEDURES.
    The American journal of physiology, 1965, Volume: 208

    Topics: Blood Vessels; Carbon; Cortisone; Edetic Acid; Endotoxins; Epinephrine; Heparin; Histamine; Mechlore

1965
[Fatal panmyelopathy under combined therapy with roentgen rays and nitrogen mustard (mitomem)].
    Wiener klinische Wochenschrift, 1960, Apr-22, Volume: 72

    Topics: Bone Marrow; Bone Marrow Diseases; Mechlorethamine; Nitrogen Mustard Compounds; Radiation Injuries;

1960
Evaluation of the significance of prognostic factors in stage III Hodgkin's disease treated with MOPP and radiotherapy.
    Cancer, 1980, Mar-15, Volume: 45, Issue:6

    Topics: Adult; Antineoplastic Agents; Drug Therapy, Combination; Evaluation Studies as Topic; Female; Hepati

1980
Total skin electron beam therapy in mycosis fungoides.
    Cancer, 1978, Volume: 42, Issue:3

    Topics: Administration, Topical; Adult; Aged; Erythema; Female; Humans; Male; Mechlorethamine; Methods; Midd

1978
The place of radiation therapy in the treatment of Hodgkin's disease.
    Cancer, 1978, Volume: 42, Issue:2 Suppl

    Topics: Adult; Drug Therapy, Combination; Female; Hodgkin Disease; Humans; Male; Mechlorethamine; Myocardial

1978
Unusual cardiac reaction to chemotherapy following mediastinal irradiation in a patient with Hodgkin's disease.
    The American journal of medicine, 1976, Volume: 60, Issue:1

    Topics: Adult; Drug Therapy, Combination; Heart; Hodgkin Disease; Humans; Male; Mechlorethamine; Mediastinal

1976
Late cardiopulmonary toxicity after treatment for Hodgkin's disease.
    British journal of cancer, 1992, Volume: 65, Issue:6

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Exerci

1992
Hodgkin's disease in children: treatment with MOPP and low-dose, extended field irradiation without laparotomy. Late results and toxicity.
    Medical and pediatric oncology, 1990, Volume: 18, Issue:4

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Combined Modali

1990
Pediatric Hodgkin's disease. Later results and toxicity--the Toronto experience.
    Cancer treatment and research, 1989, Volume: 41

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Child; Combined Modality Therapy; Follow

1989
Reduction of fatal complications from combined modality therapy in Hodgkin's disease.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1985, Volume: 3, Issue:4

    Topics: Actuarial Analysis; Acute Disease; Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Pro

1985
Combined chemotherapy and radiotherapy in carcinoma of the lung.
    The Medical journal of Australia, 1965, Sep-04, Volume: 2, Issue:10

    Topics: Adult; Aged; Humans; Lung Neoplasms; Mechlorethamine; Middle Aged; Oxides; Palliative Care; Radiatio

1965
X-radiation and alkylating agents as possible "trigger" mechanisms in the autoimmune complications of malignant lymphophroliferative disease.
    Clinical and experimental immunology, 1966, Volume: 1, Issue:1

    Topics: Adult; Aged; Anemia, Hemolytic, Autoimmune; Chlorambucil; Humans; Leukemia, Lymphoid; Lymphoma, Non-

1966