mechlorethamine has been researched along with Inflammation in 24 studies
nitrogen mustard : Compounds having two beta-haloalkyl groups bound to a nitrogen atom, as in (X-CH2-CH2)2NR.
Inflammation: A pathological process characterized by injury or destruction of tissues caused by a variety of cytologic and chemical reactions. It is usually manifested by typical signs of pain, heat, redness, swelling, and loss of function.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Glomerular fibrin deposition is important in the pathogenesis of renal failure and crescent formation in glomerulonephritis." | 7.67 | Macrophage-induced glomerular fibrin deposition in experimental glomerulonephritis in the rabbit. ( Holdsworth, SR; Tipping, PG, 1985) |
| "Glomerular fibrin deposition is important in the pathogenesis of renal failure and crescent formation in glomerulonephritis." | 3.67 | Macrophage-induced glomerular fibrin deposition in experimental glomerulonephritis in the rabbit. ( Holdsworth, SR; Tipping, PG, 1985) |
| " Dose-response experiments performed with 2 to 90 per cent (v/v) zymosan-activated plasma showed a direct correlation between the rate of neutrophil influx and the degree of vascular permeability in blood flow." | 1.26 | Vascular responses during acute neutrophilic inflammation. Their relationship to in vivo neutrophil emigration. ( Issekutz, AC, 1981) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 17 (70.83) | 18.7374 |
| 1990's | 1 (4.17) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 4 (16.67) | 24.3611 |
| 2020's | 2 (8.33) | 2.80 |
| Authors | Studies |
|---|---|
| Wahler, G | 1 |
| Heck, DE | 1 |
| Heindel, ND | 1 |
| Laskin, DL | 3 |
| Laskin, JD | 3 |
| Joseph, LB | 1 |
| Smith, LC | 1 |
| Venosa, A | 2 |
| Gow, AJ | 2 |
| Kumar, D | 1 |
| Tewari-Singh, N | 1 |
| Agarwal, C | 1 |
| Jain, AK | 1 |
| Inturi, S | 1 |
| Kant, R | 1 |
| White, CW | 1 |
| Agarwal, R | 1 |
| Gow, JG | 1 |
| Hall, L | 1 |
| Malaviya, R | 1 |
| Kunak, ZI | 1 |
| Macit, E | 1 |
| Yaren, H | 1 |
| Yaman, H | 1 |
| Cakir, E | 1 |
| Aydin, I | 1 |
| Turker, T | 1 |
| Kurt, YG | 1 |
| Ozcan, A | 1 |
| Uysal, B | 1 |
| Isbilir, S | 1 |
| Akgul, EO | 1 |
| Cayci, T | 1 |
| Korkmaz, A | 1 |
| Kenar, L | 1 |
| Całkosiński, I | 1 |
| Rosińczuk-Tonderys, J | 1 |
| Dzierzba, K | 1 |
| Bazan, J | 1 |
| Całkosińska, M | 1 |
| Majda, J | 1 |
| Dobrzyński, M | 1 |
| Bronowicka-Szydełko, A | 1 |
| ERLSBACHER, O | 1 |
| GEISBERGER, H | 1 |
| POPP, A | 1 |
| SCHEUER-KARPIN, R | 1 |
| ROCHA, H | 1 |
| FEKETY, FR | 1 |
| NOTTI, P | 1 |
| SANTORO, G | 1 |
| ALEXANDROWICZ, J | 1 |
| Uriuhara, T | 1 |
| Movat, HZ | 1 |
| Orange, RP | 1 |
| Valentine, MD | 1 |
| Austen, KF | 1 |
| Issekutz, AC | 2 |
| Ripley, M | 1 |
| Rochon, Y | 1 |
| Pi-Jimenez, E | 1 |
| Wright, B | 1 |
| Quinn, TD | 1 |
| Polk, HC | 1 |
| Edwards, MJ | 1 |
| Werb, Z | 1 |
| Dingle, JT | 1 |
| Giannella, RA | 1 |
| Jampol, LM | 1 |
| West, C | 1 |
| Goldberg, MF | 1 |
| Rosenbaum, JT | 1 |
| Raymond, W | 1 |
| Seymour, BW | 1 |
| Wolfrom, JA | 1 |
| Enkel, H | 1 |
| Howes, EL | 1 |
| Murphy, KR | 1 |
| Wilson, MC | 1 |
| Irvin, CG | 1 |
| Glezen, LS | 1 |
| Marsh, WR | 1 |
| Haslett, C | 1 |
| Henson, PM | 1 |
| Larsen, GL | 1 |
| Holdsworth, SR | 1 |
| Tipping, PG | 1 |
| Tung, KS | 1 |
| Hawk, WA | 1 |
| Goth, A | 1 |
24 other studies available for mechlorethamine and Inflammation
| Article | Year |
|---|---|
Antioxidant/stress response in mouse epidermis following exposure to nitrogen mustard.
Topics: Alkylating Agents; Animals; Antioxidants; Apoptosis; Cyclooxygenase 2; DNA Damage; Epidermis; Glutat | 2020 |
Transcriptional profiling of lung macrophages during pulmonary injury induced by nitrogen mustard.
Topics: Animals; Chemical Warfare Agents; Gene Expression Regulation; Inflammation; Lung Injury; Macrophages | 2020 |
Nitrogen mustard exposure of murine skin induces DNA damage, oxidative stress and activation of MAPK/Akt-AP1 pathway leading to induction of inflammatory and proteolytic mediators.
Topics: Animals; Chemical Warfare Agents; DNA Damage; Gene Expression Regulation, Enzymologic; Histones; Inf | 2015 |
Regulation of Nitrogen Mustard-Induced Lung Macrophage Activation by Valproic Acid, a Histone Deacetylase Inhibitor.
Topics: Animals; Bronchoalveolar Lavage Fluid; Cell Proliferation; Histone Deacetylase Inhibitors; Inflammat | 2017 |
Protective effects of melatonin and S-methylisothiourea on mechlorethamine induced nephrotoxicity.
Topics: Animals; Chemical Warfare Agents; Disease Models, Animal; Inflammation; Isothiuronium; Kidney Diseas | 2012 |
Mechlorethamine (NTG) effects on the erythrocytic and leukocytic blood parameters during experimentally induced pleuritis in rats.
Topics: Alkylating Agents; Animals; Carrageenan; Disease Models, Animal; Dose-Response Relationship, Drug; E | 2012 |
[Antiphlogistic therapy with nitrogen mustards].
Topics: Inflammation; Mechlorethamine; Nitrogen Mustard Compounds | 1956 |
[Nitrogen mustard as an antiphlogistic drug].
Topics: Inflammation; Mechlorethamine; Nitrogen Mustard Compounds | 1956 |
ACUTE INFLAMMATION IN THE RENAL CORTEX AND MEDULLA FOLLOWING THERMAL INJURY.
Topics: Animals; Burns; Burns, Electric; Escherichia coli; Escherichia coli Infections; Hydronephrosis; Infl | 1964 |
[Experimental research on the antiphlogistic power of nitrogen mustard].
Topics: Inflammation; Mechlorethamine; Nitrogen Mustard Compounds | 1961 |
The curative properties of nitrogen mustard (nitrogranulogen) in inflammatory diseases.
Topics: Humans; Inflammation; Mechlorethamine; Nitrogen Mustard Compounds | 1950 |
Role of PMN-leukocyte lysosomes in tissue injury, inflammation and hypersensitivity. V. Partial suppresssion in leukopenic rabbits of vascular hyper-permeability due to thermal injury.
Topics: Animals; Burns; Capillary Permeability; Inflammation; Leukopenia; Lysosomes; Mechlorethamine; Micros | 1967 |
Release of slow-reacting substance of anaphylaxis in the rat: polymorphonuclear leukocyte.
Topics: Anaphylaxis; Animals; Antigens; Complement System Proteins; Inflammation; Leukopenia; Male; Mast Cel | 1967 |
A role for hemolysin in Escherichia coli-induced inflammation in granulocytopenic rabbits.
Topics: Agranulocytosis; Animals; Blood Platelets; Capillary Permeability; Escherichia coli Infections; Fema | 1984 |
Vascular responses during acute neutrophilic inflammation. Their relationship to in vivo neutrophil emigration.
Topics: Animals; Aspirin; Capillary Permeability; Cell Movement; Chemotactic Factors; Escherichia coli; Hype | 1981 |
Hyperthermic isolated limb perfusion increases circulating levels of inflammatory cytokines.
Topics: Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Cancer, Regional Perfusion; Combined M | 1995 |
Lysosomes as modulators of cellular functions. Influence on the synthesis and secretion of non-lysosomal materials.
Topics: Animals; Arthritis; Cell Membrane; Cytoskeleton; Endocytosis; Exocytosis; Eye; Fibroblasts; Hydrolas | 1976 |
Importance of the intestinal inflammatory reaction in salmonella-mediated intestinal secretion.
Topics: Animals; Cholera Toxin; Ileum; Inflammation; Intestinal Diseases; Intestinal Mucosa; Leukocyte Count | 1979 |
Therapy of scleritis with cytotoxic agents.
Topics: Adult; Antineoplastic Agents; Cyclophosphamide; Dapsone; Drug Therapy, Combination; Eye Diseases; Fe | 1978 |
The effect of corticosteroids or nitrogen mustard on aqueous humor chemotactic activity induced by intravitreal endotoxin.
Topics: Animals; Aqueous Humor; Chemotactic Factors; Chemotaxis, Leukocyte; Endotoxins; Inflammation; Male; | 1986 |
The requirement for polymorphonuclear leukocytes in the late asthmatic response and heightened airways reactivity in an animal model.
Topics: Animals; Asthma; Bronchi; Bronchial Provocation Tests; Bronchial Spasm; Immune Sera; Inflammation; L | 1986 |
Macrophage-induced glomerular fibrin deposition in experimental glomerulonephritis in the rabbit.
Topics: Animals; Basement Membrane; Blood Coagulation Tests; Disease Models, Animal; Fibrin; Glomerulonephri | 1985 |
In vivo study of the inflammatory basophilic responses in mucosal colitis and transmural colitis.
Topics: Adrenocorticotropic Hormone; Adult; Basophils; Colitis; Colonic Diseases, Functional; Diagnosis, Dif | 1968 |
Interaction of carbohydrates and anti-inflammatory drugs with mast cells in the rat.
Topics: Animals; Anti-Inflammatory Agents; Carbohydrates; Colchicine; Depression, Chemical; Dextrans; Drug A | 1968 |