mechlorethamine has been researched along with Infertility in 10 studies
nitrogen mustard : Compounds having two beta-haloalkyl groups bound to a nitrogen atom, as in (X-CH2-CH2)2NR.
Infertility: A reduced or absent capacity to reproduce.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Buserelin (d-Ser-[TBU]6 LHRH ethylamide) was prescribed in two different dosage schedules to twenty men, and in a single dosage schedule to eight women." | 2.66 | Failure to preserve fertility in patients with Hodgkin's disease. ( Ahmed, R; Besser, GM; Crowther, D; Gregory, W; Malpas, JS; Rees, LH; Shalet, S; Smith, D; Waxman, JH; Wrigley, PF, 1987) |
| "Most patients with early-stage Hodgkin's disease can now be cured by one of several therapeutic approaches." | 2.37 | Early-stage Hodgkin's disease: current approaches to treatment. ( MacKenzie, R; Rusthoven, JJ, 1985) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (50.00) | 18.7374 |
| 1990's | 3 (30.00) | 18.2507 |
| 2000's | 2 (20.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| JACKSON, H | 1 |
| FOX, BW | 1 |
| CRAIG, AW | 1 |
| Diehl, V | 2 |
| Fuchs, M | 1 |
| Mauch, PM | 1 |
| Weinstein, H | 1 |
| Botnick, L | 1 |
| Belli, J | 1 |
| Cassady, JR | 1 |
| Bokemeyer, C | 1 |
| Schmoll, HJ | 1 |
| van Rhee, J | 1 |
| Kuczyk, M | 1 |
| Schuppert, F | 1 |
| Poliwoda, H | 1 |
| Carde, P | 1 |
| Cavalli, F | 1 |
| Franklin, J | 1 |
| Longo, DL | 1 |
| Glatstein, E | 1 |
| Duffey, PL | 1 |
| Young, RC | 1 |
| Hubbard, SM | 1 |
| Urba, WJ | 1 |
| Wesley, MN | 1 |
| Raubitschek, A | 1 |
| Jaffe, ES | 1 |
| Wiernik, PH | 1 |
| Glode, LM | 1 |
| Shannon, JM | 1 |
| Malik, N | 1 |
| Nett, T | 1 |
| Waxman, JH | 1 |
| Ahmed, R | 1 |
| Smith, D | 1 |
| Wrigley, PF | 1 |
| Gregory, W | 1 |
| Shalet, S | 1 |
| Crowther, D | 1 |
| Rees, LH | 1 |
| Besser, GM | 1 |
| Malpas, JS | 1 |
| Rosenberg, SA | 1 |
| Kaplan, HS | 1 |
| Rusthoven, JJ | 1 |
| MacKenzie, R | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Optimization of the Primary Therapy for Patients With Hodgkin's Lymphoma and Evaluation of the Positron Emission Tomography (PET) as a Diagnostic Tool for Primary Staging and Assessment of the Effects of the Therapy[NCT00188149] | Phase 4 | 300 participants | Interventional | 2000-05-31 | Recruiting | ||
| Ovarian Tissue Freezing For Fertility Preservation In Women Facing A Fertility Threatening Medical Diagnosis Or Treatment Regimen: A Study By The National Physicians Cooperative of the Oncofertility Consortium At Northwestern University[NCT00902720] | Phase 4 | 25 participants (Anticipated) | Interventional | 2009-05-31 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
3 reviews available for mechlorethamine and Infertility
| Article | Year |
|---|---|
Will BEACOPP be the standard for high risk Hodgkin lymphoma patients in advanced stages?
Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Clinical Trials as Topic; Cyclophosphamid | 2007 |
Is escalated BEACOPP a standard therapy for advanced Hodgkin's disease?
Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Chlorambucil; Clinical Trials, Phase III | 2000 |
Early-stage Hodgkin's disease: current approaches to treatment.
Topics: Acute Disease; Adult; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Fem | 1985 |
3 trials available for mechlorethamine and Infertility
| Article | Year |
|---|---|
Radiation therapy versus combination chemotherapy in the treatment of early-stage Hodgkin's disease: seven-year results of a prospective randomized trial.
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Female; Follow-Up Studies; | 1991 |
Failure to preserve fertility in patients with Hodgkin's disease.
Topics: Amenorrhea; Animals; Antineoplastic Combined Chemotherapy Protocols; Buserelin; Dogs; Female; Follic | 1987 |
The evolution and summary results of the Stanford randomized clinical trials of the management of Hodgkin's disease: 1962-1984.
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Child; Clinical Trials as Topic; Combine | 1985 |
4 other studies available for mechlorethamine and Infertility
| Article | Year |
|---|---|
The effect of alkylating agents on male rat fertility.
Topics: Alkylating Agents; Animals; Fertility; Fertility Agents; Germ Cells; Infertility; Male; Mechloretham | 1959 |
An evaluation of long-term survival and treatment complications in children with Hodgkin's disease.
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Child; Drug Therapy, Combination; Evalua | 1983 |
Long-term gonadal toxicity after therapy for Hodgkin's and non-Hodgkin's lymphoma.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Cyclop | 1994 |
Protection of rat spermatogenic epithelium from damage induced by procarbazine chemotherapy.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Child; Danazol; Epithelium; Estradiol; Gona | 1990 |