Page last updated: 2024-10-30

mechlorethamine and Hypoxia

mechlorethamine has been researched along with Hypoxia in 9 studies

nitrogen mustard : Compounds having two beta-haloalkyl groups bound to a nitrogen atom, as in (X-CH2-CH2)2NR.

Hypoxia: Sub-optimal OXYGEN levels in the ambient air of living organisms.

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19905 (55.56)18.7374
1990's3 (33.33)18.2507
2000's0 (0.00)29.6817
2010's1 (11.11)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Johnson, KM1
Parsons, ZD1
Barnes, CL1
Gates, KS1
BENKO, S1
SZUCS, Z1
RAK, K1
Stratford, IJ1
Adams, GE1
Horsman, MR1
Kandaiya, S1
Rajaratnam, S1
Smith, E1
Williamson, C1
Wilson, WR2
Moselen, JW1
Cliffe, S1
Denny, WA2
Ware, DC1
Ferry, DM1
Tercel, M1
Anderson, RF1
Hill, RP1
Martin, LF1
Tucker, A1
Munroe, ML1
Reeves, JT1
Willemze, R1
Walker, RI1
Herion, JC1
Palmer, JG1
Kwon, CH1
Blanco, DR1
Baturay, N1

Other Studies

9 other studies available for mechlorethamine and Hypoxia

ArticleYear
Toward hypoxia-selective DNA-alkylating agents built by grafting nitrogen mustards onto the bioreductively activated, hypoxia-selective DNA-oxidizing agent 3-amino-1,2,4-benzotriazine 1,4-dioxide (tirapazamine).
    The Journal of organic chemistry, 2014, Aug-15, Volume: 79, Issue:16

    Topics: Alkylating Agents; Antineoplastic Agents; Cyclic N-Oxides; DNA Damage; Gas Chromatography-Mass Spect

2014
[Loading experiments on erythrocyte formation in normal dogs and in bone marrow lesions].
    Orvosi hetilap, 1957, Apr-07, Volume: 98, Issue:14

    Topics: Animals; Bone Diseases; Bone Marrow; Dogs; Erythrocytes; Hematopoietic System; Hypoxia; Mechloretham

1957
The interaction of misonidazole with radiation, chemotherapeutic agents, or heat: a preliminary report.
    Cancer clinical trials, 1980,Fall, Volume: 3, Issue:3

    Topics: Animals; Antineoplastic Agents; Cell Survival; Cells, Cultured; Cisplatin; Cricetinae; Hot Temperatu

1980
Exploiting tumor hypoxia through bioreductive release of diffusible cytotoxins: the cobalt(III)-nitrogen mustard complex SN 24771.
    International journal of radiation oncology, biology, physics, 1994, May-15, Volume: 29, Issue:2

    Topics: Antineoplastic Agents; Cell Survival; Cells, Cultured; Diffusion; Hypoxia; Mechlorethamine; Nitrogen

1994
Reduction of nitroarylmethyl quaternary ammonium prodrugs of mechlorethamine by radiation.
    Radiation research, 1998, Volume: 149, Issue:3

    Topics: Antineoplastic Agents; Hypoxia; Mechlorethamine; Nitrogen Mustard Compounds; Oxidation-Reduction; Pr

1998
Combined nitrogen mustard--radiation studies with a mouse tumor.
    International journal of radiation oncology, biology, physics, 1979, Volume: 5, Issue:9

    Topics: Animals; Cell Survival; Hypoxia; Male; Mechlorethamine; Mice; Mice, Inbred C3H; Oxygen; Sarcoma, Exp

1979
Lung mast cells and hypoxic pulmonary vasoconstriction in cats.
    Respiration; international review of thoracic diseases, 1978, Volume: 35, Issue:2

    Topics: Animals; Cats; Female; Hypoxia; Lung; Male; Mast Cells; Mechlorethamine; Pulmonary Artery; Vascular

1978
Marrow culture in diffusion chambers in rabbits. II. Effect of competing demands for red cell and white cell production on cell growth.
    Blood, 1978, Volume: 51, Issue:6

    Topics: Anemia; Animals; Bone Marrow Cells; Cells, Cultured; Endotoxins; Erythrocytes; Erythropoietin; Hemat

1978
p-(Methylsulfinyl)phenyl nitrogen mustard as a novel bioreductive prodrug selective against hypoxic tumors.
    Journal of medicinal chemistry, 1992, May-29, Volume: 35, Issue:11

    Topics: Animals; Antineoplastic Agents; Cell Survival; CHO Cells; Cricetinae; Hypoxia; Liver; Mechlorethamin

1992