mechlorethamine has been researched along with Hypospermatogenesis in 11 studies
nitrogen mustard : Compounds having two beta-haloalkyl groups bound to a nitrogen atom, as in (X-CH2-CH2)2NR.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Buserelin (d-Ser-[TBU]6 LHRH ethylamide) was prescribed in two different dosage schedules to twenty men, and in a single dosage schedule to eight women." | 2.66 | Failure to preserve fertility in patients with Hodgkin's disease. ( Ahmed, R; Besser, GM; Crowther, D; Gregory, W; Malpas, JS; Rees, LH; Shalet, S; Smith, D; Waxman, JH; Wrigley, PF, 1987) |
| "More than 50% of patients with non Hodgkin's lymphomas (NHL) are long-term survivors." | 1.29 | [Semen preservation and gonadal toxicity in the treatment of non Hodgkin lymphoma. Experience at the Gustave-Roussy Institute from 1980 to 1993]. ( Auger, J; Bendahmane, B; Decaudin, D; Koscielny, S; Munck, JN; Naccache, P, 1996) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (63.64) | 18.7374 |
| 1990's | 4 (36.36) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| DAGG, CP | 1 |
| KARNOFSKY, DA | 1 |
| TOOLAN, HW | 1 |
| RODDY, J | 1 |
| Dein, RA | 1 |
| Mennuti, MT | 1 |
| Kovach, P | 1 |
| Gabbe, SG | 1 |
| Pasqualini, T | 1 |
| Waxman, JH | 2 |
| Terry, YA | 1 |
| Wrigley, PF | 2 |
| Malpas, JS | 2 |
| Rees, LH | 2 |
| Besser, GM | 2 |
| Lister, TA | 1 |
| Whitehead, E | 1 |
| Shalet, SM | 1 |
| Jones, PH | 1 |
| Beardwell, CG | 1 |
| Deakin, DP | 1 |
| Dhabhar, BN | 1 |
| Malhotra, H | 1 |
| Joseph, R | 1 |
| Garde, S | 1 |
| Bhasin, S | 1 |
| Sheth, A | 1 |
| Advani, SH | 2 |
| Naccache, P | 1 |
| Decaudin, D | 1 |
| Koscielny, S | 1 |
| Bendahmane, B | 1 |
| Auger, J | 1 |
| Munck, JN | 1 |
| Kulkarni, SS | 1 |
| Sastry, PS | 1 |
| Saikia, TK | 1 |
| Parikh, PM | 1 |
| Gopal, R | 1 |
| Andrieu, JM | 1 |
| Colonna, P | 1 |
| Viviani, S | 1 |
| Santoro, A | 1 |
| Ragni, G | 1 |
| Bonfante, V | 1 |
| Bestetti, O | 1 |
| Bonadonna, G | 1 |
| Ahmed, R | 1 |
| Smith, D | 1 |
| Gregory, W | 1 |
| Shalet, S | 1 |
| Crowther, D | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Ovarian Tissue Freezing For Fertility Preservation In Women Facing A Fertility Threatening Medical Diagnosis Or Treatment Regimen: A Study By The National Physicians Cooperative of the Oncofertility Consortium At Northwestern University[NCT00902720] | Phase 4 | 25 participants (Anticipated) | Interventional | 2009-05-31 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for mechlorethamine and Hypospermatogenesis
| Article | Year |
|---|---|
The reproductive potential of young men and women with Hodgkin's disease.
Topics: Adult; Amenorrhea; Antineoplastic Combined Chemotherapy Protocols; Congenital Abnormalities; Female; | 1984 |
3 trials available for mechlorethamine and Hypospermatogenesis
| Article | Year |
|---|---|
Are ABVD and MOPP/ABV truly equivalent for treating Hodgkin's disease at advanced stages?
Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Dacarbazine; Disease-Free Survival; Doxor | 1998 |
Gonadal toxicity after combination chemotherapy for Hodgkin's disease. Comparative results of MOPP vs ABVD.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Dacarbazine; Doxorubic | 1985 |
Failure to preserve fertility in patients with Hodgkin's disease.
Topics: Amenorrhea; Animals; Antineoplastic Combined Chemotherapy Protocols; Buserelin; Dogs; Female; Follic | 1987 |
7 other studies available for mechlorethamine and Hypospermatogenesis
| Article | Year |
|---|---|
Serial passage of human tumors in chick embryo: growth inhibition by nitrogen mustard.
Topics: Humans; Male; Mechlorethamine; Neoplasm Transplantation; Neoplasms; Nitrogen Mustard Compounds; Olig | 1954 |
[Testicular damage caused by chemotherapy in acute lymphoblastic leukemia].
Topics: Adolescent; Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Child; C | 1983 |
Gonadal function in Hodgkin's disease: long-term follow-up of chemotherapy.
Topics: Adolescent; Adult; Amenorrhea; Antineoplastic Combined Chemotherapy Protocols; Child; Drug Therapy, | 1982 |
Gonadal function after combination chemotherapy for Hodgkin's disease in childhood.
Topics: Adolescent; Antineoplastic Agents; Child; Child, Preschool; Drug Therapy, Combination; Female; Hodgk | 1982 |
Gonadal function in prepubertal boys following treatment for Hodgkin's disease.
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Cyclophosphamid | 1993 |
[Semen preservation and gonadal toxicity in the treatment of non Hodgkin lymphoma. Experience at the Gustave-Roussy Institute from 1980 to 1993].
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Combined Modality Ther | 1996 |
Gonadal function following ABVD therapy for Hodgkin's disease.
Topics: Adolescent; Adult; Antibiotics, Antineoplastic; Antineoplastic Agents; Antineoplastic Agents, Alkyla | 1997 |