mechlorethamine has been researched along with Histiocytosis, Langerhans-Cell in 30 studies
nitrogen mustard : Compounds having two beta-haloalkyl groups bound to a nitrogen atom, as in (X-CH2-CH2)2NR.
Histiocytosis, Langerhans-Cell: A group of disorders resulting from the abnormal proliferation of and tissue infiltration by LANGERHANS CELLS which can be detected by their characteristic Birbeck granules (X bodies), or by monoclonal antibody staining for their surface CD1 ANTIGENS. Langerhans-cell granulomatosis can involve a single organ, or can be a systemic disorder.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To study the exact frequency and the histological features of cutaneous intolerance to mechlorethamine (CIM) hydrochloride therapy in patients with cutaneous T-cell lymphomas, including Langerhans cell histiocytosis." | 7.70 | A prospective study of cutaneous intolerance to topical mechlorethamine therapy in patients with cutaneous T-cell lymphomas. French Study Group of Cutaneous Lymphomas. ( Avril, MF; Bagot, M; Beylot-Barry, M; Delaunay, M; Estève, E; Grange, F; Joly, P; Laroche, L; Souteyrand, P; Thomine, E; Vaillant, L; Wechsler, J, 1999) |
| "To study the exact frequency and the histological features of cutaneous intolerance to mechlorethamine (CIM) hydrochloride therapy in patients with cutaneous T-cell lymphomas, including Langerhans cell histiocytosis." | 3.70 | A prospective study of cutaneous intolerance to topical mechlorethamine therapy in patients with cutaneous T-cell lymphomas. French Study Group of Cutaneous Lymphomas. ( Avril, MF; Bagot, M; Beylot-Barry, M; Delaunay, M; Estève, E; Grange, F; Joly, P; Laroche, L; Souteyrand, P; Thomine, E; Vaillant, L; Wechsler, J, 1999) |
| "Skin lesions in Langerhans cell histiocytosis (LCH) are often painful and difficult to treat." | 1.31 | Long term follow up of topical mustine treatment for cutaneous langerhans cell histiocytosis. ( Atherton, DA; Harper, JI; Hoeger, PH; Nanduri, VR; Pritchard, J, 2000) |
| "Otitis externa is a common symptom of Langerhans' cell histiocytosis, and occurs in half of all children with the disease." | 1.29 | Otitis externa in Langerhans' cell histiocytosis--the successful use of topical nitrogen mustard. ( Albert, DM; Birchall, MA; Hadfield, PJ, 1994) |
| "In 16 children with multisystem Langerhans cell histiocytosis (mean age 22 months, range 5 to 36 months) severe symptomatic skin involvement was treated with topical nitrogen mustard (mechlorethamine hydrochloride)." | 1.28 | Topical nitrogen mustard: an effective treatment for cutaneous Langerhans cell histiocytosis. ( Atherton, DJ; Broadbent, V; Pritchard, J; Sheehan, MP, 1991) |
| "Two infants suffering from histiocytosis X were treated successfully with a topically applied nitrogen mustard." | 1.26 | Histiocytosis X in two infants--treated with topical nitrogen mustard. ( Zachariae, H, 1979) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 12 (40.00) | 18.7374 |
| 1990's | 11 (36.67) | 18.2507 |
| 2000's | 4 (13.33) | 29.6817 |
| 2010's | 2 (6.67) | 24.3611 |
| 2020's | 1 (3.33) | 2.80 |
| Authors | Studies |
|---|---|
| Bui, AN | 1 |
| Puleo, AE | 1 |
| Canales, AL | 1 |
| Jacobsen, ED | 1 |
| LeBoeuf, NR | 1 |
| Schlinsog, AS | 1 |
| Kreft, B | 1 |
| Marsch, WC | 1 |
| Régis, A | 1 |
| Ben Salem, D | 1 |
| Lambert, A | 1 |
| Couaillier, JF | 1 |
| Casasnovas, O | 1 |
| Piard, F | 1 |
| Krausé, D | 1 |
| Lindahl, LM | 1 |
| Fenger-Grøn, M | 1 |
| Iversen, L | 1 |
| Treat, JR | 1 |
| Suchin, KR | 1 |
| James, WD | 1 |
| Lee, LW | 1 |
| Azfar, RS | 1 |
| Yan, AC | 1 |
| Thivolet, J | 2 |
| Cambazard, F | 1 |
| Euvrard, S | 2 |
| Hermier, M | 1 |
| Kanitakis, J | 2 |
| Nethercott, JR | 1 |
| Murray, AH | 1 |
| Medwidsky, W | 1 |
| Chalvardjian, A | 1 |
| Lookingbill, DP | 1 |
| Berman, B | 1 |
| Chang, DL | 1 |
| Shupack, JL | 1 |
| Lemarchand-Venencie, F | 1 |
| Saurat, JH | 1 |
| Goodfellow, A | 1 |
| Cream, JJ | 1 |
| Seed, WA | 1 |
| Rodriguez-Valdes, J | 1 |
| Cordoba, M | 1 |
| Perez-Espinosa, J | 1 |
| Forssman, T | 1 |
| Fluhr, J | 1 |
| Djawari, D | 1 |
| Gloor, M | 1 |
| Rumpelt, HJ | 1 |
| Estève, E | 2 |
| Pruvost, F | 1 |
| Bensaïd, P | 1 |
| Machet, MC | 1 |
| de Muret, A | 1 |
| Vaillant, L | 2 |
| Lorette, G | 1 |
| Hadfield, PJ | 1 |
| Birchall, MA | 1 |
| Albert, DM | 1 |
| Sayrak, H | 1 |
| Doğan, B | 1 |
| Harmanyeri, Y | 1 |
| Oztek, I | 1 |
| Cingil, H | 1 |
| Irving, RM | 1 |
| Broadbent, V | 3 |
| Jones, NS | 1 |
| Gerlach, B | 1 |
| Stein, A | 1 |
| Fischer, R | 1 |
| Wozel, G | 1 |
| Dittert, DD | 1 |
| Richter, G | 1 |
| Morand, JJ | 1 |
| Colineau, X | 1 |
| Carsuzaa, F | 1 |
| Lescout, JM | 1 |
| Carloz, E | 1 |
| Jacquet, P | 1 |
| Benderitter, T | 1 |
| Bagot, M | 1 |
| Joly, P | 1 |
| Souteyrand, P | 1 |
| Beylot-Barry, M | 1 |
| Delaunay, M | 1 |
| Avril, MF | 1 |
| Laroche, L | 1 |
| Grange, F | 1 |
| Thomine, E | 1 |
| Wechsler, J | 1 |
| Hoeger, PH | 1 |
| Nanduri, VR | 1 |
| Harper, JI | 1 |
| Atherton, DA | 1 |
| Pritchard, J | 2 |
| Zachariae, H | 1 |
| Saurel, J | 1 |
| Savin de Larclause, AM | 1 |
| Mercier, M | 1 |
| Rabreau, M | 1 |
| Tessier, D | 1 |
| Clément, A | 1 |
| Shanley, DJ | 1 |
| Lerud, KS | 1 |
| Luetkehans, TJ | 1 |
| Sheehan, MP | 1 |
| Atherton, DJ | 2 |
| Schmitt, D | 1 |
| Wong, E | 1 |
| Holden, CA | 1 |
| Verret, JL | 1 |
| Hadet, M | 1 |
| Brunet, A | 1 |
| Elnekave, FL | 1 |
| Avenel, M | 1 |
| Monk, BE | 1 |
| McKee, PH | 1 |
| du Vivier, A | 1 |
1 review available for mechlorethamine and Histiocytosis, Langerhans-Cell
| Article | Year |
|---|---|
[Langerhans-cell histiocytosis of the vulva. General review and a case history].
Topics: Administration, Topical; Aged; Aged, 80 and over; Biopsy; Female; Histiocytosis, Langerhans-Cell; Hu | 1992 |
29 other studies available for mechlorethamine and Histiocytosis, Langerhans-Cell
| Article | Year |
|---|---|
Cutaneous Langerhans Cell Histiocytosis Responsive to Topical Nitrogen Mustard.
Topics: Administration, Cutaneous; Aged; Aged, 80 and over; Alkylating Agents; Biopsy; Female; Histiocytosis | 2020 |
Cutaneous Langerhans cell histiocytosis - an indication for dermatological pharmacotherapy with topical nitrogen mustard.
Topics: Administration, Cutaneous; Adolescent; Dermatologic Agents; Hand Dermatoses; Histiocytosis, Langerha | 2018 |
[Concomitant pulmonary Langerhans cell histiocytosis and malignant lymphoma: report of two cases].
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Biopsy; Bleomycin; Combined Modality Therapy; | 2009 |
Topical nitrogen mustard therapy in patients with Langerhans cell histiocytosis.
Topics: Administration, Cutaneous; Adolescent; Adult; Child; Child, Preschool; Dermatitis, Irritant; Dermato | 2012 |
Topical nitrogen mustard ointment with occlusion for Langerhans' cell histiocytosis of the scalp.
Topics: Administration, Cutaneous; Adult; Antineoplastic Agents, Alkylating; Histiocytosis, Langerhans-Cell; | 2003 |
A 4-month-old boy with diaper dermatitis. Langerhans cell histiocytosis.
Topics: Adrenal Cortex Hormones; Alkylating Agents; Diagnosis, Differential; Diaper Rash; Histiocytosis, Lan | 2008 |
[Isolated cutaneous Langerhans histiocytosis. Clinical and immunohistologic improvement after local application of nitrogen mustard].
Topics: Administration, Topical; Fluorescent Antibody Technique; Histiocytosis, Langerhans-Cell; Humans; Inf | 1984 |
Histiocytosis X in two adults. Treatment with topical mechlorethamine.
Topics: Administration, Topical; Adult; Aged; Female; Histiocytosis, Langerhans-Cell; Humans; Ilium; Male; M | 1983 |
Histiocytosis X confined to the skin of the scalp.
Topics: Administration, Topical; Adult; Female; Histiocytosis, Langerhans-Cell; Humans; Mechlorethamine; Sca | 1984 |
Histiocytosis X: treatment with topical nitrogen mustard.
Topics: Administration, Topical; Aged; Female; Histiocytosis, Langerhans-Cell; Humans; Mechlorethamine | 1980 |
[Topical therapy using nitrogen mustard (chlormethine hydrochlorate) for cutaneous manifestations of histiocytosis X (author's transl)].
Topics: Administration, Topical; Female; Histiocytosis, Langerhans-Cell; Humans; Infant; Male; Mechlorethami | 1982 |
Histiocytosis X with unusual facial and axillary ulceration responding to topical nitrogen mustard.
Topics: Adult; Axilla; Facial Dermatoses; Histiocytosis, Langerhans-Cell; Humans; Male; Mechlorethamine; Ski | 1982 |
Hand-Schüller-Christian disease: a case report.
Topics: Cytoplasmic Granules; Female; Histiocytosis, Langerhans-Cell; Humans; Mechlorethamine; Middle Aged; | 1982 |
[Treatment of Langerhans-cell histiocytosis by oral cyclosporin A and topical nitrogen mustard].
Topics: Administration, Oral; Administration, Topical; Cyclosporine; Histiocytosis, Langerhans-Cell; Humans; | 1994 |
[Langerhans-cell histiocytosis in an adult with initial vulvar involvement: 2 cases].
Topics: Adult; Diagnosis, Differential; Female; Granuloma; Histiocytes; Histiocytosis, Langerhans-Cell; Huma | 1994 |
Otitis externa in Langerhans' cell histiocytosis--the successful use of topical nitrogen mustard.
Topics: Administration, Topical; Child; Child, Preschool; Female; Histiocytosis, Langerhans-Cell; Humans; In | 1994 |
Langerhans cell histiocytosis in an adult.
Topics: Administration, Topical; Adult; Axilla; Diabetes Insipidus; Etoposide; Female; Histiocytosis, Langer | 1994 |
Langerhans' cell histiocytosis in childhood: management of head and neck manifestations.
Topics: Age of Onset; Child, Preschool; Combined Modality Therapy; Ear Diseases; Female; Head; Histiocytosis | 1994 |
[Langerhans cell histiocytosis in the elderly].
Topics: Adult; Aged; Child, Preschool; Etoposide; Female; Histiocytosis, Langerhans-Cell; Humans; Immunoenzy | 1998 |
[Vulvar and gingival ulcers and skull tumors].
Topics: Female; Gingival Hypertrophy; Histiocytosis, Langerhans-Cell; Humans; Mechlorethamine; Middle Aged; | 1998 |
A prospective study of cutaneous intolerance to topical mechlorethamine therapy in patients with cutaneous T-cell lymphomas. French Study Group of Cutaneous Lymphomas.
Topics: Administration, Cutaneous; Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkyla | 1999 |
Long term follow up of topical mustine treatment for cutaneous langerhans cell histiocytosis.
Topics: Administration, Topical; Alkylating Agents; Child; Child, Preschool; Dermatologic Agents; Female; Fo | 2000 |
Histiocytosis X in two infants--treated with topical nitrogen mustard.
Topics: Administration, Topical; Child, Preschool; Female; Histiocytosis, Langerhans-Cell; Humans; Infant; M | 1979 |
Development of pulmonary histiocytosis X after chemotherapy for Hodgkin disease.
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Dacarbazine; Doxorubicin; Fem | 1990 |
Topical nitrogen mustard: an effective treatment for cutaneous Langerhans cell histiocytosis.
Topics: Administration, Topical; Child, Preschool; Drug Evaluation; Female; Histiocytosis, Langerhans-Cell; | 1991 |
Ultrastructural observation of Charcot-Leyden crystals in mechlorethamine-treated cutaneous lesions of histiocytosis X.
Topics: Crystallization; Histiocytosis, Langerhans-Cell; Humans; Infant; Male; Mechlorethamine; Microscopy, | 1986 |
Histiocytosis X presenting as intertrigo and responding to topical nitrogen mustard.
Topics: Female; Histiocytosis, Langerhans-Cell; Humans; Infant; Intertrigo; Mechlorethamine | 1986 |
[Histiocytosis X with perianovulvar eosinophilic granuloma. Favorable effect of the local application of nitrogen mustard onto anovulvar lesions].
Topics: Administration, Topical; Aged; Anus Diseases; Eosinophilic Granuloma; Female; Histiocytosis, Langerh | 1985 |
Histiocytosis X of the scalp and face responding to topical nitrogen mustard.
Topics: Administration, Topical; Adult; Facial Neoplasms; Histiocytosis, Langerhans-Cell; Humans; Male; Mech | 1985 |