Page last updated: 2024-10-30

mechlorethamine and Heart Diseases

mechlorethamine has been researched along with Heart Diseases in 9 studies

nitrogen mustard : Compounds having two beta-haloalkyl groups bound to a nitrogen atom, as in (X-CH2-CH2)2NR.

Heart Diseases: Pathological conditions involving the HEART including its structural and functional abnormalities.

Research Excerpts

ExcerptRelevanceReference
" It is suggested that total focal dosage used after chemotherapy be reviewed since total dosage for the entire lymph collector in excess of 30 Gy might contribute to hazards of cardiopathology."1.35[Multivariate analysis of risk of cardiac complications in Hodgkin's lymphoma]. ( Bozhenko, VK; Datsenko, PV; Ivashin, AV; Mel'nik, IuD; Pan'shin, GA; Podol'skiĭ, PN; Sotnikov, VM, 2009)
"Cardiotoxicity is a well recognized side effect of anthracyclines (doxorubicin and epirubicin) or antracenadiones (mitoxantrone) at cumulative or high doses."1.29Late cardiac toxicity of doxorubicin, epirubicin, and mitoxantrone therapy for Hodgkin's disease in adults. ( Arévila, N; Avilés, A; Díaz Maqueo, JC; García, R; Gómez, T; Nambo, MJ, 1993)
"Although most patients with Hodgkin's disease refractory to MOPP treatment will respond to either ABVD or B-CAVe chemotherapy, subsequent long-term disease-free survival is unusual."1.27Combination chemotherapy for advanced Hodgkin's disease after failure of MOPP: ABVD and B-CAVe. ( Harker, WG; Kushlan, P; Rosenberg, SA, 1984)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19905 (55.56)18.7374
1990's2 (22.22)18.2507
2000's2 (22.22)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Podol'skiĭ, PN1
Datsenko, PV1
Pan'shin, GA1
Sotnikov, VM1
Mel'nik, IuD1
Ivashin, AV1
Bozhenko, VK1
SANSON, J1
SLODKI, S1
GRUHN, JG1
TOURNEUR, R1
GRIVAUX, M1
LAMOTTE-BARRILLON, S1
Diehl, V1
Fuchs, M1
Harker, WG1
Kushlan, P1
Rosenberg, SA1
Avilés, A1
Arévila, N1
Díaz Maqueo, JC1
Gómez, T1
García, R1
Nambo, MJ1
Allavena, C1
Conroy, T1
Aletti, P1
Bey, P1
Lederlin, P1
Santoro, A1
Bonadonna, G1
Valagussa, P1
Zucali, R1
Viviani, S1
Villani, F1
Pagnoni, AM1
Bonfante, V1
Musumeci, R1
Crippa, F1
Watchie, J1
Coleman, CN1
Raffin, TA1
Cox, RS1
Raubitschek, AA1
Fahey, T1
Hoppe, RT1
Van Kessel, A1

Reviews

1 review available for mechlorethamine and Heart Diseases

ArticleYear
Will BEACOPP be the standard for high risk Hodgkin lymphoma patients in advanced stages?
    Transfusion and apheresis science : official journal of the World Apheresis Association : official journal of the European Society for Haemapheresis, 2007, Volume: 37, Issue:1

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Clinical Trials as Topic; Cyclophosphamid

2007

Trials

1 trial available for mechlorethamine and Heart Diseases

ArticleYear
Long-term results of combined chemotherapy-radiotherapy approach in Hodgkin's disease: superiority of ABVD plus radiotherapy versus MOPP plus radiotherapy.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1987, Volume: 5, Issue:1

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Clinical Trials as Topic; Combined

1987

Other Studies

7 other studies available for mechlorethamine and Heart Diseases

ArticleYear
[Multivariate analysis of risk of cardiac complications in Hodgkin's lymphoma].
    Voprosy onkologii, 2009, Volume: 55, Issue:4

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Female; Heart;

2009
MYOCARDIAL ABSCESSES.
    American heart journal, 1963, Volume: 66

    Topics: Abscess; Anti-Bacterial Agents; Aspergillosis; Candidiasis; Clostridium; Electrocardiography; Escher

1963
[DIGESTIVE INTOLERANCE TO DIGITALIN, CYTOSTATIC DRUGS AND VARIOUS THERAPEUTIC DRUGS. THEIR TREATMENT WITH METHOCLOPRAMIDE].
    La semaine des hopitaux : organe fonde par l'Association d'enseignement medical des hopitaux de Paris, 1964, Oct-14, Volume: 40

    Topics: Antiemetics; Antitubercular Agents; Cobalt Isotopes; Cyclophosphamide; Cytostatic Agents; Digitalis

1964
Combination chemotherapy for advanced Hodgkin's disease after failure of MOPP: ABVD and B-CAVe.
    Annals of internal medicine, 1984, Volume: 101, Issue:4

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Combined Modalit

1984
Late cardiac toxicity of doxorubicin, epirubicin, and mitoxantrone therapy for Hodgkin's disease in adults.
    Leukemia & lymphoma, 1993, Volume: 11, Issue:3-4

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Doxorubicin; Epirubicin; Female; Follow-Up St

1993
Late cardiopulmonary toxicity after treatment for Hodgkin's disease.
    British journal of cancer, 1992, Volume: 65, Issue:6

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Exerci

1992
Minimal long-term cardiopulmonary dysfunction following treatment for Hodgkin's disease.
    International journal of radiation oncology, biology, physics, 1987, Volume: 13, Issue:4

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Body Composition; Elec

1987