mechlorethamine has been researched along with Head and Neck Neoplasms in 31 studies
nitrogen mustard : Compounds having two beta-haloalkyl groups bound to a nitrogen atom, as in (X-CH2-CH2)2NR.
Head and Neck Neoplasms: Soft tissue tumors or cancer arising from the mucosal surfaces of the LIP; oral cavity; PHARYNX; LARYNX; and cervical esophagus. Other sites included are the NOSE and PARANASAL SINUSES; SALIVARY GLANDS; THYROID GLAND and PARATHYROID GLANDS; and MELANOMA and non-melanoma skin cancers of the head and neck. (from Holland et al., Cancer Medicine, 4th ed, p1651)
Excerpt | Relevance | Reference |
---|---|---|
" In the absence of evidence of a dose-response curve for platinum, the lower dosage schedules that can be used with acceptable toxicity on an outpatient basis should be selected." | 3.75 | Chemotherapy for squamous cell carcinoma of the head and neck: a progress report. ( Glick, JH; Taylor, SG; Zehngebot, LM, 1980) |
"Thirty-four patients with recurrent squamous cell carcinoma of the head and neck were randomized to receive the five-drug chemotherapy regimen BACON (bleomycin, adriamycin, CCNU, vincristine [Oncovin], and mechlorethamine [nitrogen mustard]; 14 patients) or the same regimen plus bacillus Calmette-Gu erin (BCG) by scarification (20 patients)." | 2.64 | Chemotherapy versus chemoimmunotherapy of head and neck cancer: report of a randomized study. ( Gutterman, JU; Hersh, EM; Livingston, RB; Richman, SP; Suen, JY, 1976) |
"Besides human 2008 ovarian cancer cells we also found that human lung (A549) and head and neck cancer cells (SCC 25) were transiently sensitized by cisplatin." | 1.29 | Factors influencing the drug sensitization of human tumor cells for in situ lipofection. ( Huang, L; Son, K, 1996) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 28 (90.32) | 18.7374 |
1990's | 2 (6.45) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 1 (3.23) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Fenn, JE | 1 |
Udelsman, R | 1 |
CLIFFORD, P | 1 |
CLIFT, RA | 2 |
DUFF, JK | 1 |
HENRY, J | 1 |
LEBRUN, J | 1 |
SIMON, S | 1 |
SMETS, W | 1 |
MALHERBE, E | 2 |
SEALY, R | 2 |
HELMAN, P | 2 |
ANDERSON, J | 2 |
WESTBURY, G | 1 |
HARRIES, JR | 2 |
BROWN, F | 1 |
BEECHER, JL | 1 |
OETTGEN, HF | 1 |
HANNA, DC | 1 |
GAISFORD, JC | 1 |
GOLDWYN, RM | 1 |
APPAIX, A | 1 |
DEVIN, R | 1 |
PECH, A | 1 |
GARCIN, M | 2 |
SPITALIER, JM | 2 |
BEAHRS, OH | 1 |
CALDAROLA, VT | 1 |
HARRISON, EG | 1 |
CLAPP, P | 1 |
TAYAO, MS | 1 |
MILLER, DG | 1 |
LAWRENCE, W | 1 |
AMALRIC, R | 1 |
ROUX, G | 1 |
DUMOULIN, H | 1 |
DESGEORGE, Y | 1 |
HARTUNG, L | 1 |
KLOPP, CT | 1 |
SMITH, DF | 1 |
ALFORD, TC | 1 |
Glick, JH | 1 |
Zehngebot, LM | 1 |
Taylor, SG | 1 |
Bartual, J | 1 |
Roquette, J | 1 |
Gil, M | 1 |
Magro, E | 1 |
Bascuas, JL | 1 |
Wade, PM | 1 |
Smith, RE | 1 |
Johns, ME | 1 |
Son, K | 1 |
Huang, L | 1 |
Dubey, SP | 1 |
Sengupta, SK | 1 |
Kaleh, LK | 1 |
Morewaya, JT | 1 |
Richman, SP | 1 |
Livingston, RB | 1 |
Gutterman, JU | 1 |
Suen, JY | 1 |
Hersh, EM | 1 |
Tattersall, MH | 1 |
Tobias, JS | 1 |
Takaue, Y | 1 |
Sullivan, MP | 1 |
Ramirez, I | 1 |
Cleary, KR | 1 |
van Eys, J | 1 |
Donegan, WL | 1 |
Harris, HS | 1 |
Srivastava, SP | 1 |
Asopa, HS | 1 |
Agarwal, HS | 1 |
Gogoi, BN | 1 |
Kenis, Y | 1 |
Lawhorn, TI | 1 |
Stone, HH | 1 |
Martin, JD | 1 |
Hill, GJ | 1 |
Larsen, RR | 1 |
Pommatau, E | 1 |
Brunat, M | 1 |
Mayer, H | 1 |
Dargent, M | 1 |
Garas, J | 1 |
Nikolaides, G | 1 |
Ramantanis, G | 1 |
Tourlas, G | 1 |
Geogakas, A | 1 |
Tsatsaris, S | 1 |
Spanoudanis, C | 1 |
Politis, A | 1 |
Yonemoto, RH | 1 |
Byron, RL | 1 |
Riihimaki, DU | 1 |
Keating, JL | 1 |
4 reviews available for mechlorethamine and Head and Neck Neoplasms
Article | Year |
---|---|
Chemotherapy for squamous cell carcinoma of the head and neck: a progress report.
Topics: Antineoplastic Agents; Bleomycin; Carcinoma, Squamous Cell; Chlorambucil; Clinical Trials as Topic; | 1980 |
Response of esthesioneuroblastoma to chemotherapy. Report of five cases and review of the literature.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Child; Combined Modality Therapy; | 1984 |
Chemotherapy of residual disease in solid tumours.
Topics: Colonic Neoplasms; Cyclophosphamide; Floxuridine; Fluorouracil; Head and Neck Neoplasms; Humans; Lun | 1971 |
Chemotherapy in solid tumors of childhood.
Topics: Abdominal Neoplasms; Adolescent; Child; Child, Preschool; Cyclophosphamide; Dactinomycin; Eye Neopla | 1972 |
3 trials available for mechlorethamine and Head and Neck Neoplasms
Article | Year |
---|---|
Chemotherapy for squamous cell carcinoma of the head and neck: a progress report.
Topics: Antineoplastic Agents; Bleomycin; Carcinoma, Squamous Cell; Chlorambucil; Clinical Trials as Topic; | 1980 |
Chemotherapy versus chemoimmunotherapy of head and neck cancer: report of a randomized study.
Topics: Adult; Aged; Antineoplastic Agents; BCG Vaccine; Bleomycin; Carcinoma, Squamous Cell; Doxorubicin; F | 1976 |
How strong is the case for intensive cancer chemotherapy?
Topics: Antineoplastic Agents; Burkitt Lymphoma; Clinical Trials as Topic; Cyclophosphamide; Dose-Response R | 1976 |
25 other studies available for mechlorethamine and Head and Neck Neoplasms
Article | Year |
---|---|
First use of intravenous chemotherapy cancer treatment: rectifying the record.
Topics: Antineoplastic Agents; Head and Neck Neoplasms; History, 20th Century; Humans; Infusions, Intravenou | 2011 |
Nitrogen-mustard therapy combined with autologous marrow infusion.
Topics: Bone Marrow; Bone Marrow Transplantation; Head and Neck Neoplasms; Mechlorethamine; Mustard Plant; N | 1961 |
[Regional intraarterial perfusion of nitrogen mustard and simultaneous irradiation of extensive cancers of the head and neck].
Topics: Head and Neck Neoplasms; Humans; Mechlorethamine; Neoplasms; Nitrogen Mustard Compounds | 1960 |
Contributions to the treatment of cancer of the head and neck. Nitrogen mustard toxicity and bone marrow infusion.
Topics: Bone Marrow; Bone Marrow Transplantation; Head; Head and Neck Neoplasms; Humans; Mechlorethamine; Ne | 1961 |
Intraarterial chemotherapy and x-ray therapy in cancer of the head and neck. Technique, methods, results and complications.
Topics: Head; Head and Neck Neoplasms; Humans; Mechlorethamine; Methotrexate; Neck; Neoplasms; Thiotepa; X-R | 1963 |
CONTINUOUS INTRA-ARTERIAL INFUSION AND INTERMITTENT INTRA-ARTERIAL INJECTION.
Topics: Antineoplastic Agents; Brain Neoplasms; Chemotherapy, Cancer, Regional Perfusion; Ethoglucid; Head a | 1963 |
HAEMODYNAMIC EFFECTS OF OCCLUSION OF ABDOMINAL AORTA DURING NITROGEN MUSTARD THERAPY.
Topics: Aorta; Aorta, Abdominal; Black People; Chemotherapy, Cancer, Regional Perfusion; Head; Head and Neck | 1963 |
INTRA-ARTERIAL NITROGEN MUSTARD FOR CONTROL OF PAIN IN HEAD AND NECK CANCER.
Topics: Head; Head and Neck Neoplasms; Injections; Injections, Intra-Arterial; Mechlorethamine; Neoplasms; P | 1963 |
[REGIONAL CHEMOTHERAPY OF HEAD AND NECK CANCER (APROPOS OF 24 INFUSIONS AND 19 REGIONAL ARTERIAL PERFUSIONS)].
Topics: Antineoplastic Agents; Chemotherapy, Cancer, Regional Perfusion; Facial Neoplasms; Head; Head and Ne | 1963 |
TREATMENT OF CANCER OF THE HEAD AND NECK BY CHEMOTHERAPY.
Topics: Alopecia; Diarrhea; Erythema; Head; Head and Neck Neoplasms; Injections, Intra-Arterial; Leukopenia; | 1964 |
RESULTS OF REGIONAL CHEMOTHERAPY OF NEOPLASMS OF THE UPPER BODY BY TEMPORARY MID-TORSO VASCULAR OCCLUSION.
Topics: Alkylating Agents; Bone Marrow; Breast Neoplasms; Catheterization; Chemotherapy, Cancer, Regional Pe | 1964 |
HEMODYNAMIC EFFECTS OF OCCLUSION OF THE ABDOMINAL AORTA DURING NITROGEN-MUSTARD THERAPY.
Topics: Aorta; Aorta, Abdominal; Blood Pressure Determination; Blood Volume Determination; Chemotherapy, Can | 1964 |
[APROPOS OF TREATMENT OF ADVANCED TUMORS OF THE HEAD AND NECK BY SIMULTANEOUS COMBINED RADIATION-ARTERIAL INFUSIONS OF NITROGEN MUSTARD].
Topics: Drug Therapy; Facial Neoplasms; Head and Neck Neoplasms; Humans; Injections, Intra-Arterial; Mandibu | 1964 |
Palliation achieved in carcinoma of the head and neck with intra-arterial chemotherapy.
Topics: Head and Neck Neoplasms; Humans; Mechlorethamine; Neck; Nitrogen Mustard Compounds; Palliative Care | 1961 |
Twelve years of experience with cytotoxic therapy in malignant tumors of the neck and head.
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cyclophosphamide; | 1982 |
Factors influencing the drug sensitization of human tumor cells for in situ lipofection.
Topics: Animals; Antineoplastic Agents; Bleomycin; Cation Exchange Resins; Chloramphenicol O-Acetyltransfera | 1996 |
Adult head and neck lymphomas in Papua New Guinea: a retrospective study of 70 cases.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Burkitt Lymphoma; Combined Modali | 1999 |
Second malignant neoplasm in treated Hodgkin's disease. Report of a patient and scope of the problem.
Topics: Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Child; Combined Modality Therapy; G | 1986 |
Factors influencing the success of arterial infusion chemotherapy for cancer of the head and neck.
Topics: Age Factors; Aged; Antineoplastic Agents; Bleomycin; Carcinoma, Basal Cell; Carcinoma, Squamous Cell | 1972 |
Intra-arterial cytotoxic therapy and x-ray therapy for cancer of the head and neck.
Topics: Adenoma, Pleomorphic; Carcinoma, Squamous Cell; Facial Neoplasms; Fibrosarcoma; Head; Head and Neck | 1965 |
The use and efficacy of intra--arterial injections of chemotherapeutic drugs in advanced cases of oral carcinomas.
Topics: Cyclophosphamide; Facial Neoplasms; Head and Neck Neoplasms; Humans; Injections, Intra-Arterial; Mec | 1967 |
Cancer chemotherapy. I. Methods, agents and overall results in 400 patients.
Topics: Adenocarcinoma; Amides; Androgens; Breast Neoplasms; Colonic Neoplasms; Cyclophosphamide; Estrogens; | 1972 |
Complete regression of metastatic tumors of the adult with antimitotic treatment.
Topics: Adolescent; Adult; Antineoplastic Agents; Choriocarcinoma; Cyclophosphamide; Dactinomycin; Female; F | 1974 |
Surgical chemotherapy for treatment of experimental tumors (animals) and far advanced tumors (humans).
Topics: Animals; Chemotherapy, Cancer, Regional Perfusion; Head and Neck Neoplasms; Humans; Injections, Intr | 1972 |
Historic and current intra-arterial chemotherapy.
Topics: Antineoplastic Agents; Carcinoma, Squamous Cell; Catheterization; Chemotherapy, Cancer, Regional Per | 1970 |