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mechlorethamine and Glomerulosclerosis, Focal Segmental

mechlorethamine has been researched along with Glomerulosclerosis, Focal Segmental in 3 studies

nitrogen mustard : Compounds having two beta-haloalkyl groups bound to a nitrogen atom, as in (X-CH2-CH2)2NR.

Glomerulosclerosis, Focal Segmental: A clinicopathological syndrome or diagnostic term for a type of glomerular injury that has multiple causes, primary or secondary. Clinical features include PROTEINURIA, reduced GLOMERULAR FILTRATION RATE, and EDEMA. Kidney biopsy initially indicates focal segmental glomerular consolidation (hyalinosis) or scarring which can progress to globally sclerotic glomeruli leading to eventual KIDNEY FAILURE.

Research Excerpts

ExcerptRelevanceReference
"Mechlorethamine has been assessed in 28 patients with idiopathic nephrotic syndrome previously treated with prednisone only."7.67[Effect of mechlorethamine in idiopathic nephrotic syndrome in childhood]. ( Canals, MJ; Cervera, A; Gómez Campderá, FJ; Gómez Campderá, J; López Gómez, JM; Luque, A; Morales, JL, 1984)
"Mechlorethamine has been assessed in 28 patients with idiopathic nephrotic syndrome previously treated with prednisone only."3.67[Effect of mechlorethamine in idiopathic nephrotic syndrome in childhood]. ( Canals, MJ; Cervera, A; Gómez Campderá, FJ; Gómez Campderá, J; López Gómez, JM; Luque, A; Morales, JL, 1984)
"Approximately 30% of children with focal segmental glomerulosclerosis enter remission following treatment with corticosteroids."2.38Immunosuppressive therapy in the nephrotic syndrome in children. ( Trompeter, RS, 1989)
"This case shows that relapse of Hodgkin's disease may occur after a 10 year interval and furthermore it may preceded by nephrotic syndrome."1.27Glomerulonephritis preceding late relapse of Hodgkin's disease. ( Lynn, WA; Marcus, RE, 1988)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19903 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Gómez Campderá, FJ1
López Gómez, JM1
Cervera, A1
Gómez Campderá, J1
Canals, MJ1
Morales, JL1
Luque, A1
Trompeter, RS1
Lynn, WA1
Marcus, RE1

Reviews

1 review available for mechlorethamine and Glomerulosclerosis, Focal Segmental

ArticleYear
Immunosuppressive therapy in the nephrotic syndrome in children.
    Pediatric nephrology (Berlin, Germany), 1989, Volume: 3, Issue:2

    Topics: Adrenal Cortex Hormones; Child; Child, Preschool; Chlorambucil; Cyclophosphamide; Cyclosporins; Glom

1989

Other Studies

2 other studies available for mechlorethamine and Glomerulosclerosis, Focal Segmental

ArticleYear
[Effect of mechlorethamine in idiopathic nephrotic syndrome in childhood].
    Anales espanoles de pediatria, 1984, Volume: 20, Issue:8

    Topics: Child; Child, Preschool; Chlorambucil; Cyclophosphamide; Drug Tolerance; Female; Glomerulosclerosis,

1984
Glomerulonephritis preceding late relapse of Hodgkin's disease.
    Postgraduate medical journal, 1988, Volume: 64, Issue:751

    Topics: Antineoplastic Combined Chemotherapy Protocols; Female; Glomerulonephritis; Glomerulosclerosis, Foca

1988