Page last updated: 2024-10-30

mechlorethamine and Gaucher Disease

mechlorethamine has been researched along with Gaucher Disease in 1 studies

nitrogen mustard : Compounds having two beta-haloalkyl groups bound to a nitrogen atom, as in (X-CH2-CH2)2NR.

Gaucher Disease: An autosomal recessive disorder caused by a deficiency of acid beta-glucosidase (GLUCOSYLCERAMIDASE) leading to intralysosomal accumulation of glycosylceramide mainly in cells of the MONONUCLEAR PHAGOCYTE SYSTEM. The characteristic Gaucher cells, glycosphingolipid-filled HISTIOCYTES, displace normal cells in BONE MARROW and visceral organs causing skeletal deterioration, hepatosplenomegaly, and organ dysfunction. There are several subtypes based on the presence and severity of neurological involvement.

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19901 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Sharer, LR1
Barondess, JA1
Silver, RT1
Gray, GF1

Other Studies

1 other study available for mechlorethamine and Gaucher Disease

ArticleYear
Association of Hodgkin disease and Gaucher disease.
    Archives of pathology, 1974, Volume: 98, Issue:6

    Topics: Adult; Autopsy; Biopsy; Gaucher Disease; Hodgkin Disease; Humans; Liver; Lymph Nodes; Lymphocytes; M

1974