Page last updated: 2024-10-30

mechlorethamine and Eye Injuries

mechlorethamine has been researched along with Eye Injuries in 6 studies

nitrogen mustard : Compounds having two beta-haloalkyl groups bound to a nitrogen atom, as in (X-CH2-CH2)2NR.

Eye Injuries: Damage or trauma inflicted to the eye by external means. The concept includes both surface injuries and intraocular injuries.

Research Excerpts

ExcerptRelevanceReference
" SM can cause devastating injuries, depending on the dosage of SM exposure, route of exposure, as well as the physiological conditions of the individuals exposed."2.82Research models of sulfur mustard- and nitrogen mustard-induced ocular injuries and potential therapeutics. ( Agarwal, R; Mishra, N, 2022)
"Corneal edema was assessed by pachymetry and the extent of neovascularization was graded by length of longest vessel in each quadrant."1.36Doxycycline hydrogels as a potential therapy for ocular vesicant injury. ( Anumolu, SS; Babin, MC; Beloni, J; Desantis, A; Deshmukh, M; Gallo, MA; Gerecke, DR; Gordon, MK; Hahn, RA; Heindel, ND; Lacey, CJ; Schlager, JJ; Sinko, PJ; Svoboda, KK, 2010)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19902 (33.33)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (33.33)24.3611
2020's2 (33.33)2.80

Authors

AuthorsStudies
Mishra, N1
Agarwal, R1
Umejiego, E1
Paramo, R1
Zafiris, A1
Mullane, E1
Bargagna-Mohan, P1
Mohan, R1
Ilhan, A1
Yolcu, U1
Oztas, E1
Erdem, U1
UHDE, GI1
Gordon, MK1
Desantis, A1
Deshmukh, M1
Lacey, CJ1
Hahn, RA1
Beloni, J1
Anumolu, SS1
Schlager, JJ1
Gallo, MA1
Gerecke, DR1
Heindel, ND1
Svoboda, KK1
Babin, MC1
Sinko, PJ1
Bito, LZ1

Reviews

2 reviews available for mechlorethamine and Eye Injuries

ArticleYear
Research models of sulfur mustard- and nitrogen mustard-induced ocular injuries and potential therapeutics.
    Experimental eye research, 2022, Volume: 223

    Topics: Animals; Chemical Warfare Agents; Cornea; Eye Injuries; Humans; Irritants; Mechlorethamine; Mustard

2022
Species differences in the responses of the eye to irritation and trauma: a hypothesis of divergence in ocular defense mechanisms, and the choice of experimental animals for eye research.
    Experimental eye research, 1984, Volume: 39, Issue:6

    Topics: Aging; Animals; Anterior Chamber; Aotus trivirgatus; Aqueous Humor; Biological Evolution; Blood; Cat

1984

Other Studies

4 other studies available for mechlorethamine and Eye Injuries

ArticleYear
A corneo-retinal hypercitrullination axis underlies ocular injury to nitrogen mustard.
    Experimental eye research, 2023, Volume: 231

    Topics: Animals; Cornea; Eye Injuries; Gliosis; Irritants; Mechlorethamine; Mice; Mustard Gas; Retina; Retin

2023
Therapeutic effects of proanthocyanidin and coenzyme Q10 on nitrogen mustard-induced ocular injury.
    Arquivos brasileiros de oftalmologia, 2018, Volume: 81, Issue:3

    Topics: Animals; Antioxidants; Burns, Chemical; Chemical Warfare Agents; Disease Models, Animal; Eye Injurie

2018
Burns of the upper respiratory tract and eyes from a nitrogen mustard gas (1149); a clinical study.
    Archives of otolaryngology, 1946, Volume: 44, Issue:6

    Topics: Burns; Ethylamines; Eye Injuries; Gas Poisoning; Humans; Mechlorethamine; Mustard Gas; Mustard Plant

1946
Doxycycline hydrogels as a potential therapy for ocular vesicant injury.
    Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics, 2010, Volume: 26, Issue:5

    Topics: Animals; Anti-Bacterial Agents; Basement Membrane; Corneal Diseases; Corneal Edema; Corneal Neovascu

2010