mechlorethamine has been researched along with Experimental Neoplasms in 165 studies
nitrogen mustard : Compounds having two beta-haloalkyl groups bound to a nitrogen atom, as in (X-CH2-CH2)2NR.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A preliminary analysis of our double high-dose chemotherapy with stem cell rescue (HD-SCR) clinical trial for breast cancer, and preclinical cross-resistant studies, suggested that melphalan (M) adversely affected response to subsequent chemotherapy, i." | 3.70 | Double high-dose chemotherapy with stem cell rescue (HD-SCR) in patients with breast cancer - effect of sequence. ( Ara, G; Bunnell, C; Elias, A; Frei, E; Richardson, P; Teicher, B; Tew, K; Wheeler, C, 2000) |
| "d-1 alone or in combination with chlormethine (Chl) 0." | 1.29 | [Antitumor activity of thevetoside alone and in combination with chlormethine in vivo]. ( Huang, ZQ; Li, CC; Zhang, XW, 1994) |
| "HN2 was a potent carcinogen, producing squamous cell carcinomas in 9 of 33 mice in 1 series." | 1.26 | Tumorigenic effect of topical mechlorethamine, BCNU and CCNU in mice. ( Smuckler, EA; Zackheim, HS, 1980) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 162 (98.18) | 18.7374 |
| 1990's | 2 (1.21) | 18.2507 |
| 2000's | 1 (0.61) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| PECZENIK, O | 1 |
| SATO, H | 5 |
| ARUJI, T | 1 |
| KAZIWARA, K | 3 |
| MASSZI, F | 1 |
| NEMETH, L | 4 |
| SELLEI, C | 2 |
| TILL, G | 1 |
| HESTON, WE | 1 |
| DVORSZKY, K | 1 |
| WARABIOKA, K | 1 |
| SATOH, H | 5 |
| KAISE, A | 1 |
| HADDOW, A | 1 |
| SKIMKIN, MB | 1 |
| ODASHIMA, S | 4 |
| NAKAMURA, K | 3 |
| ISHIDATE, M | 2 |
| SAKURAI, Y | 6 |
| YOSHIDA, T | 4 |
| IMAMURA, H | 1 |
| SHIMADA, J | 1 |
| TAKAHASHI, T | 2 |
| MANABE, H | 1 |
| SUGIMOTO, A | 1 |
| KONO, O | 1 |
| TERASHIMA, H | 1 |
| AZUMA, S | 1 |
| MURATA, Y | 1 |
| TAZAKA, S | 1 |
| ROKUJO, T | 1 |
| ISHIHARA, T | 1 |
| YOSIDA, TH | 1 |
| OBOSHI, S | 1 |
| AOKI, K | 1 |
| SAKURABA, T | 1 |
| ISHIKURA, T | 1 |
| SATO, M | 1 |
| HEBBORN, P | 1 |
| DANIELLI, JF | 1 |
| KRAVCHENKO, AI | 1 |
| DANNEBERG, P | 2 |
| DRUCKREY, H | 4 |
| KAISER, K | 2 |
| LO, HW | 3 |
| MECKE, R | 2 |
| NIEPER, HA | 2 |
| SCHMAHL, D | 4 |
| SHIRAHA, Y | 1 |
| SAKAI, K | 1 |
| KISHIWADA, Y | 1 |
| MATSUI, E | 1 |
| KONDO, T | 3 |
| TSUKUI, K | 1 |
| HONJO, O | 1 |
| YAMAUCHI, H | 1 |
| NAKAZATO, H | 1 |
| HIRONO, I | 3 |
| SAWADA, Y | 1 |
| KOLLER, PC | 1 |
| VERONESI, U | 1 |
| MCDONALD, GO | 1 |
| CRUZ, EP | 1 |
| COLE, WH | 2 |
| KELLNER, B | 2 |
| HIRSCHBERG, E | 1 |
| GELLHORN, A | 1 |
| GUMP, WS | 1 |
| LUCK, JM | 1 |
| BARVICK, L | 1 |
| GOODSON, LH | 1 |
| KIELER, E | 1 |
| NOUCHI, F | 1 |
| SAWASAKI, C | 1 |
| TOKUDA, G | 1 |
| INOUE, K | 1 |
| KAWASHIMA, Y | 1 |
| KANNO, K | 1 |
| TAMANO, T | 1 |
| ARNOLD, H | 1 |
| BOURSEAUX, F | 1 |
| BROCK, N | 3 |
| McDONALD, CT | 1 |
| HOWIE, JS | 1 |
| WEEKS, PM | 1 |
| THOMAS, CG | 1 |
| HOLCZINGER, L | 1 |
| ERNST, H | 1 |
| RATHENOW, HW | 1 |
| EICHHORN, HJ | 1 |
| WILMANNS, H | 1 |
| DISCHLER, W | 1 |
| LAPIS, K | 2 |
| HOLZER, H | 1 |
| KROGER, H | 1 |
| KUDRIAVINA, NA | 1 |
| SYRKIN, AB | 1 |
| FROHBERG, H | 1 |
| KUK, BT | 1 |
| STEINHOFF, D | 1 |
| JACKSON, K | 1 |
| McGREW, E | 1 |
| BALO, J | 2 |
| KENDREY, G | 2 |
| JUHASZ, J | 2 |
| BESZNYAK, I | 2 |
| HUMPHREY, LJ | 2 |
| HOPPE, ET | 3 |
| DEPEYSTER, FA | 2 |
| SPASSKAIA, IG | 1 |
| BIHARI, E | 1 |
| KHOMCHENOVSKII, EI | 1 |
| CLIFFTON, EE | 3 |
| AGOSTINO, D | 4 |
| PELLET, M | 1 |
| BROSSON, J | 1 |
| POHLE, K | 1 |
| MATTHIES, E | 1 |
| MENG, K | 1 |
| RYAN, RF | 1 |
| LOCHRIDGE, HL | 1 |
| JACKSON, DA | 1 |
| SAWATARI, K | 1 |
| ANDERSEN, H | 1 |
| DAVYDOVA, SIa | 1 |
| SAPOZHNIKOVA, MB | 1 |
| GATI, E | 1 |
| WOEBER, K | 1 |
| LENDLE, K | 1 |
| HEIN, W | 1 |
| EIFINGER, FF | 1 |
| SHINGLETON, WW | 1 |
| SANDERS, AP | 1 |
| ROBINSON, KP | 1 |
| ZALDIVAR, RS | 1 |
| COHN, I | 1 |
| GONZALES, EA | 1 |
| FLOYD, CE | 1 |
| FREEMAN, CM | 1 |
| ATIK, M | 1 |
| YAMADA, T | 2 |
| IWANAMI, Y | 1 |
| BABA, T | 1 |
| CALCUTT, G | 2 |
| CONNORS, TA | 1 |
| DUNNING, WF | 2 |
| TARNOWSKI, G | 1 |
| KULKA, P | 1 |
| BATES, L | 1 |
| SAFIER, S | 1 |
| SATTERWHITE, H | 1 |
| SOLNEY, E | 1 |
| DENG, RS | 1 |
| ZEZZANETO, L | 1 |
| SOERENSEN, B | 1 |
| SALIBA, AM | 1 |
| GRECCHI, R | 1 |
| THIELE, EH | 1 |
| ARISON, RN | 1 |
| BOXER, GE | 1 |
| KREPSZ, I | 1 |
| PUPP, A | 1 |
| GYERGYAY, F | 1 |
| INCH, WR | 1 |
| MCCREDIE, JA | 1 |
| CURTIS, MR | 1 |
| LAYDE, JP | 1 |
| BASERGA, R | 2 |
| ISAKA, H | 2 |
| ALEXANDER, JW | 1 |
| ALTEMEIER, WA | 1 |
| TSOU, KC | 1 |
| SU, HC | 1 |
| DECOSSE, JJ | 1 |
| ROGERS, LS | 1 |
| GOLDER, RH | 1 |
| MARTIN-GUZMAN, G | 1 |
| JONES, J | 1 |
| GOLDSTEIN, NO | 1 |
| ROTENBERG, S | 1 |
| RUTMAN, RJ | 2 |
| LEVIN, G | 1 |
| SUGIURA, K | 2 |
| BROWN, GB | 1 |
| YANCEY, ST | 1 |
| SATOU, H | 1 |
| KURNATOWSKI, A | 1 |
| PECK, RM | 1 |
| BREUNINGER, ER | 1 |
| MILLER, AJ | 1 |
| CREECH, HJ | 1 |
| ZIMMER, H | 1 |
| SILL, AD | 1 |
| BURKE, WJ | 1 |
| BROWN, JE | 1 |
| WEATHERBEE, C | 1 |
| CURTIS, DH | 1 |
| ZIMEL, H | 1 |
| MACRINEANU, A | 1 |
| KOJIMA, K | 1 |
| KACHI, H | 1 |
| OHASHI, A | 1 |
| SASAOKA, I | 1 |
| CONKLIN, JW | 1 |
| UPTON, AC | 1 |
| CHRISTENBERRY, KW | 1 |
| ABELL, CW | 1 |
| FALK, HL | 1 |
| SHIMKIN, MB | 2 |
| WEISBURGER, EK | 1 |
| WEISBURGER, JH | 1 |
| GUBAREFF, N | 1 |
| MIURA, Y | 2 |
| MORIYAMA, Y | 1 |
| HASEGAWA, S | 1 |
| FUKUI, N | 1 |
| O'BRIEN, DE | 1 |
| WESTOVER, JD | 1 |
| ROBINS, RK | 1 |
| CHENG, CC | 1 |
| ROGERS, S | 1 |
| KRATOCHVIL, M | 1 |
| KNOTZ, F | 1 |
| JUDIN, J | 1 |
| GODAL, A | 1 |
| WINKLER, A | 1 |
| AIKO, I | 1 |
| KAWASHIMA, N | 1 |
| KU, KY | 1 |
| LU, KH | 1 |
| HU, CC | 1 |
| ASO, Y | 1 |
| MASHIMA, Y | 1 |
| NAGATA, I | 1 |
| STEELE, WJ | 1 |
| PRICE, CC | 1 |
| STOCK, CC | 1 |
| BOYLAND, E | 1 |
| HORNING, ES | 1 |
| Bruce, WR | 1 |
| Kaplan, NC | 1 |
| Yuhas, JM | 3 |
| Spellman, JM | 1 |
| Culo, F | 1 |
| Arrick, BA | 1 |
| Nathan, CF | 1 |
| Hofer, D | 1 |
| Dubitsky, A | 1 |
| Marti, J | 1 |
| Santoro, MG | 1 |
| Reilly, P | 1 |
| Jaffe, BM | 1 |
| Presant, CA | 1 |
| Carr, D | 1 |
| Zackheim, HS | 1 |
| Smuckler, EA | 1 |
| Shafer, RH | 1 |
| Chase, ES | 1 |
| Zhang, XW | 1 |
| Huang, ZQ | 1 |
| Li, CC | 1 |
| Frei, E | 1 |
| Ara, G | 1 |
| Teicher, B | 1 |
| Bunnell, C | 1 |
| Richardson, P | 1 |
| Wheeler, C | 1 |
| Tew, K | 1 |
| Elias, A | 1 |
| Grieder, A | 1 |
| Maurer, R | 1 |
| Stähelin, H | 1 |
| Maruyama, Y | 2 |
| Terui, S | 1 |
| Inaba, M | 1 |
| Broder, LE | 1 |
| Weintraub, BD | 1 |
| Rosen, SW | 1 |
| Demirchoglian, IG | 1 |
| Babasian, OV | 1 |
| Galstian, DA | 1 |
| Tarleton, AE | 1 |
| Harman, JG | 1 |
| Wheeler, RH | 1 |
| Dirks, JW | 1 |
| Lunardi, I | 1 |
| Nemiroff, MJ | 1 |
| Raju, MR | 1 |
| Bains, E | 1 |
| Jett, J | 1 |
| Twentyman, PR | 2 |
| Bleehen, NM | 1 |
| Hall, AG | 1 |
| Tilby, MJ | 1 |
| Kwok, TT | 1 |
| Gibson, GR | 2 |
| Stephens, FO | 2 |
| Lehner, T | 1 |
| Rosenoer, VM | 1 |
| Smith, J | 1 |
| von Ardenne, M | 1 |
| Reitnauer, PG | 1 |
| Sudo, I | 1 |
| Tashiro, T | 1 |
| Ting, SM | 1 |
| Preece, AV | 1 |
| Imaizumi, M | 1 |
| Edwards, AJ | 2 |
| Rowland, GF | 2 |
| Terent'eva, TG | 1 |
| Fomina, IP | 1 |
| Navashin, SM | 1 |
| Garas, J | 1 |
| Nikolaides, G | 1 |
| Ramantanis, G | 1 |
| Tourlas, G | 1 |
| Geogakas, A | 1 |
| Tsatsaris, S | 1 |
| Spanoudanis, C | 1 |
| Politis, A | 1 |
| Kudo, T | 1 |
| Elson, LA | 1 |
| Cambanis, A | 1 |
| Dobre, V | 1 |
| Niculescu-Duvăz, I | 1 |
| Sasaki, T | 1 |
| McDonough, M | 1 |
| Thatcher, D | 1 |
| Wieder, R | 1 |
| Gaudin, D | 1 |
| Yielding, KL | 1 |
| Perez, CA | 1 |
| Olson, J | 1 |
| Girolami, A | 1 |
| Unger, E | 1 |
| Appelgren, LE | 1 |
| Bäckström, J | 1 |
| Clemedson, CJ | 1 |
| Nilsson, A | 1 |
| Sörbo, B | 1 |
| Ullberg, S | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| (PRO#11307) Phase III Randomized Study of Autologous Stem Cell Transplantation With High-dose Melphalan Versus High-dose Melphalan and Bortezomib in Patients With Multiple Myeloma 65 Year or Older[NCT01453088] | Phase 2 | 63 participants (Actual) | Interventional | 2010-06-24 | Terminated (stopped due to Lack of Accrual) | ||
| Tandem Autologous Hematopoietic Stem Cell Transplant With Melphalan Followed by Melphalan and Bortezomib in Patients With Multiple Myeloma[NCT01241708] | Phase 3 | 146 participants (Actual) | Interventional | 2010-04-08 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
(NCT01453088)
Timeframe: 1 year
| Intervention | Participants (Count of Participants) |
|---|---|
| Auto Transplant High Dose Melphalan | 27 |
| Auto Transplant High Dose Melphalan+Bortezomib | 27 |
Progression free survival of elderly patients with multiple myeloma treated with either high-dose melphalan versus high-dose melphalan and bortezomib at 3 years (NCT01453088)
Timeframe: Participants will be followed post transplant for a minimum of 3 years, and after that may be monitored as part of the study indefinitely
| Intervention | Participants (Count of Participants) |
|---|---|
| Auto Transplant High Dose Melphalan | 13 |
| Auto Transplant High Dose Melphalan+Bortezomib | 11 |
2 reviews available for mechlorethamine and Experimental Neoplasms
| Article | Year |
|---|---|
Glutathione metabolism as a determinant of therapeutic efficacy: a review.
Topics: Aminoacridines; Amsacrine; Animals; Antineoplastic Agents; Biological Transport; Carmustine; Cycloph | 1984 |
Mechanisms of action of, and modes of resistance to, alkylating agents used in the treatment of haematological malignancies.
Topics: Alkylating Agents; Animals; Antineoplastic Agents; DNA Damage; DNA, Neoplasm; Drug Design; Drug Resi | 1992 |
Mechanisms of action of, and modes of resistance to, alkylating agents used in the treatment of haematological malignancies.
Topics: Alkylating Agents; Animals; Antineoplastic Agents; DNA Damage; DNA, Neoplasm; Drug Design; Drug Resi | 1992 |
Mechanisms of action of, and modes of resistance to, alkylating agents used in the treatment of haematological malignancies.
Topics: Alkylating Agents; Animals; Antineoplastic Agents; DNA Damage; DNA, Neoplasm; Drug Design; Drug Resi | 1992 |
Mechanisms of action of, and modes of resistance to, alkylating agents used in the treatment of haematological malignancies.
Topics: Alkylating Agents; Animals; Antineoplastic Agents; DNA Damage; DNA, Neoplasm; Drug Design; Drug Resi | 1992 |
163 other studies available for mechlorethamine and Experimental Neoplasms
| Article | Year |
|---|---|
Inhibition of tumour-growth after oral and parenteral treatment with nitrogen mustards and triethylene malamine.
Topics: Animals; Humans; Mechlorethamine; Neoplasms; Neoplasms, Experimental; Nitrogen Mustard Compounds; Tr | 1952 |
[On inhibitory effects of nitrogen mustard N-oxide (MBAO) upon the ascites hepatoma].
Topics: Animals; Ascites; Carcinoma, Hepatocellular; Liver Neoplasms; Mechlorethamine; Neoplasms, Experiment | 1952 |
[Experiments with various mitosis and ferment inhibitory substances on Paramecia and on animal tumors].
Topics: Animals; Ciliophora; Coloring Agents; Mechlorethamine; Mitosis; Neoplasms; Neoplasms, Experimental; | 1952 |
Occurrence of tumors in mice injected subcutaneously with sulfur mustard and nitrogen mustard.
Topics: Animals; Mechlorethamine; Mice; Mustard Gas; Neoplasms; Neoplasms, Experimental; Nitrogen Mustard Co | 1953 |
[Cancerogenic and other side-effects of podophyllin and nitrogen mustards].
Topics: Animals; Liver Neoplasms; Lung Neoplasms; Mechlorethamine; Neoplasms, Experimental; Nitrogen Mustard | 1953 |
[Experimental carcinogenesis with methyl di-(2-chloroethyl) amine-N-oxide hydrochloride (nitromin); preliminary report].
Topics: Amines; Animals; Carcinogenesis; Mechlorethamine; Neoplasms, Experimental; Oxides | 1953 |
[Nitromin inhibition of azo dye carcinogenesis; preliminary report].
Topics: Animals; Azo Compounds; Carcinogenesis; Carcinogens; Liver Neoplasms; Mechlorethamine; Neoplasms, Ex | 1953 |
[Oral administration of nitromin to the Yoshida sarcoma and the ascites hepatoma animals].
Topics: Administration, Oral; Animals; Ascites; Carcinoma, Hepatocellular; Liver Neoplasms; Liver Neoplasms, | 1953 |
Mode of action of carcinogenic agents on cells.
Topics: Animals; Carcinogens; Mechlorethamine; Neoplasms, Experimental; Nitrogen Mustard Compounds | 1953 |
Pulmonary-tumor induction in mice with chemical agents used in the clinical management of lymphomas.
Topics: Animals; Carcinogens; Lung Neoplasms; Lymphoma; Mechlorethamine; Mice; Neoplasms, Experimental; Nitr | 1954 |
Nitromin effect on epidermal carcinogenesis with methylcholanthrene; preliminary report.
Topics: Animals; Carcinogenesis; Epidermis; Mechlorethamine; Methylcholanthrene; Neoplasms, Experimental; Ni | 1954 |
[Experimental studies on chemotherapy of malignant growth employing Yoshida sarcoma animals. V. Evaluation and comparison of curative effects of compounds tested using the diagram of percentage survival].
Topics: Animals; Mechlorethamine; Neoplasms, Experimental; Nitrogen Mustard Compounds; Physiological Phenome | 1954 |
[Histochemical influences of nitromin on the ascites hepatoma].
Topics: Animals; Ascites; Carcinoma, Hepatocellular; Liver Neoplasms; Liver Neoplasms, Experimental; Mechlor | 1954 |
Nitromin effect on azo dye carcinogenesis. I.
Topics: Animals; Azo Compounds; Carcinogenesis; Carcinogens; Carcinoma, Hepatocellular; Coloring Agents; Liv | 1954 |
A study of growth of ascites hepatoma and Yoshida sarcoma in rats and changes caused by nitromin treatment.
Topics: Animals; Ascites; Carcinoma, Hepatocellular; Liver Neoplasms; Liver Neoplasms, Experimental; Mechlor | 1954 |
[Inhibitory action of the chemical compounds which inhibit Yoshida sarcoma].
Topics: Animals; Law Enforcement; Mechlorethamine; Neoplasms, Experimental; Nitrogen Mustard Compounds; Sarc | 1954 |
Studies on chemotherapy of cancer using ascites tumors of animals.
Topics: Animals; Ascites; Carcinoma, Ehrlich Tumor; Humans; Mechlorethamine; Neoplasms; Neoplasms, Experimen | 1955 |
Nitromin effect on the methylcholanthrene tumor in mice.
Topics: Animals; Mechlorethamine; Methylcholanthrene; Mice; Neoplasms; Neoplasms, Experimental; Nitrogen Mus | 1955 |
[Nitrominresistant line developed in the Ehrlich ascites carcinoma].
Topics: Animals; Ascites; Carcinoma; Mechlorethamine; Neoplasms, Experimental; Nitrogen Mustard Compounds | 1955 |
[Effect of nitromin and sarkomycin on some ascitic tumors].
Topics: Animals; Anti-Bacterial Agents; Antibiotics, Antitubercular; Mechlorethamine; Neoplasms; Neoplasms, | 1955 |
Selectivity of enzyme-activated nitrogen mustards.
Topics: Animals; Enzyme Activation; Enzyme Activators; Mechlorethamine; Neoplasms, Experimental; Nitrogen Mu | 1956 |
[Alkoxy derivatives of benzyl, di-(beta-chloroethyl), amine in experimental chemotherapy of neoplasms].
Topics: Alcohols; Amines; Animals; Mechlorethamine; Neoplasms; Neoplasms, Experimental; Nitrogen Mustard Com | 1955 |
[Comparative investigation of the chemotherapeutic action of N-oxide-mustard gas and other alkylating compounds in rat tumors].
Topics: Alkylating Agents; Animals; Ethylenediamines; Mechlorethamine; Mustard Gas; Neoplasms; Neoplasms, Ex | 1956 |
[Comparative investigation of the chemotherapeutic action of N-oxide-mustard gas and other alkylating compounds in rat tumors].
Topics: Alkylating Agents; Animals; Ethylenediamines; Mechlorethamine; Mustard Gas; Neoplasms; Neoplasms, Ex | 1956 |
[Comparative investigation of the chemotherapeutic action of N-oxide-mustard gas and other alkylating compounds in rat tumors].
Topics: Alkylating Agents; Animals; Ethylenediamines; Mechlorethamine; Mustard Gas; Neoplasms; Neoplasms, Ex | 1956 |
[Comparative investigation of the chemotherapeutic action of N-oxide-mustard gas and other alkylating compounds in rat tumors].
Topics: Alkylating Agents; Animals; Ethylenediamines; Mechlorethamine; Mustard Gas; Neoplasms; Neoplasms, Ex | 1956 |
[Effects of antitumor substances following intraarterial injections in rat tumors].
Topics: Animals; Injections, Intra-Arterial; Mechlorethamine; Neoplasms; Neoplasms, Experimental; Nitrogen M | 1956 |
Life-prolongation of Yoshida sarcoma rat under a concomitant treatment of nitromin and cysteine.
Topics: Animals; Cysteine; Humans; Life Support Care; Mechlorethamine; Neoplasms, Experimental; Nitrogen Mus | 1956 |
On production of metastases from rat tumor by nitrogen-mustard-N-oxide, x-ray, and cortisone.
Topics: Animals; Cortisone; Mechlorethamine; Mustard Plant; Neoplasms; Neoplasms, Experimental; Neoplasms, S | 1956 |
[Oncological and hematological observations on rats repeatedly injected with nitromin].
Topics: Animals; Blood; Internal Medicine; Mechlorethamine; Neoplasms, Experimental; Nitrogen Mustard Compou | 1956 |
Studies on resistant of cancer cells to nitrogen-mustard-N-oxide.
Topics: Animals; Humans; Mechlorethamine; Mustard Plant; Neoplasms, Experimental; Nitrogen; Nitrogen Mustard | 1956 |
Influence of tumor-inhibiting agents upon tumor immunity; studies with the MBAO-resistant subline of the Yoshida sarcoma.
Topics: Animals; Mechlorethamine; Neoplasms; Neoplasms, Experimental; Nitrogen Mustard Compounds; Sarcoma, Y | 1956 |
Discussion on the screening test of cancer chemotherapy.
Topics: Animals; Mechlorethamine; Neoplasms, Experimental; Nitrogen Mustard Compounds | 1956 |
Effect of p-(naphthol-2-azo-1) benzoxyethyl bis (beta-chloroethyl) amine on the methylcholanthrene tumors in mice and azo-dye hepatoma in rats.
Topics: Amines; Animals; Carcinoma, Hepatocellular; Liver Neoplasms; Mechlorethamine; Methylcholanthrene; Mi | 1956 |
The effects of a nitrogen mustard derivative of phenylalanine on experimental tumours.
Topics: Animals; Mechlorethamine; Neoplasms, Experimental; Nitrogen Mustard Compounds; Phenylalanine | 1956 |
The effect of cancer inhibitor drugs on the take of Walker carcinosarcoma 256 in rats.
Topics: Animals; Antineoplastic Agents; Carcinoma 256, Walker; Mechlorethamine; Neoplasms, Experimental; Nit | 1957 |
[Cure of experimental tumors by operation under chemotherapeutic protection].
Topics: Animals; Humans; Mechlorethamine; Neoplasms, Experimental; Nitrogen Mustard Compounds | 1957 |
Pathological and clinical effects of 1.6-bis(beta-chloraethylamino)-1.6-desoxy-D-mannite-dichlorhydrate/BCM.
Topics: Animals; Mannitol; Mechlorethamine; Neoplasms, Experimental; Nitrogen Mustard Compounds | 1957 |
Laboratory evaluation of a new nitrogen mustard, 2-[di-(2-chloroethyl)amino-methyl]benzimidazole, and of other 2-chloroethyl compounds.
Topics: Animals; Benzimidazoles; Mechlorethamine; Neoplasms, Experimental; Nitrogen Mustard Compounds | 1957 |
The action of the phenylalanine mustards and of several homologs on mouse melanoma.
Topics: Animals; Mechlorethamine; Melanoma; Melphalan; Neoplasms, Experimental; Nitrogen Mustard Compounds | 1957 |
Some observations on C57BL mice with mammary adenocarcinoma EO771 receiving combination chemotherapy.
Topics: Adenocarcinoma; Animals; Drug Therapy, Combination; Erythromycin; Folic Acid Antagonists; Mechloreth | 1957 |
The effect of methyl-bis-(beta-chloroethyl)-amine-N-oxide on two transplanted mouse mammary carcinomas.
Topics: Amines; Animals; Breast; Mechlorethamine; Neoplasms, Experimental; Nitrogen Mustard Compounds; Oxide | 1958 |
Experimental studies on chemotherapy of malignant growth employing Yoshida sarcoma animals. XVI. Determination of minimum effective dose (MED) of nitromin and other compounds by means of cytochemical detection of the PAS positive substances.
Topics: Animals; Mechlorethamine; Neoplasms, Experimental; Nitrogen Mustard Compounds; Physiological Phenome | 1957 |
[Influences of the transplantation of Yoshida ascites sarcoma and the administration of nitrogen mustard N-oxide (N.M.O. ) upon the nitrogen equilibrium of rats].
Topics: Animals; Ascites; Mechlorethamine; Neoplasms, Experimental; Nitrogen; Nitrogen Mustard Compounds; Ra | 1957 |
Experimental studies on the effects of nitromin upon tumor growth, with special respect to inhibition of metastasis production.
Topics: Animals; Mechlorethamine; Neoplasms; Neoplasms, Experimental; Neoplasms, Second Primary; Nitrogen Mu | 1957 |
[Oral administration of nitromin to the animals bearing Yoshida sarcoma and ascites hepatoma. II].
Topics: Administration, Oral; Animals; Ascites; Carcinoma, Hepatocellular; Liver Neoplasms; Mechlorethamine; | 1957 |
Chemotherapeutic action of a cyclic nitrogen mustard phosphamide ester (B 518-ASTA) in experimental tumours of the rat.
Topics: Animals; Cyclophosphamide; Dimethoate; Esters; Mechlorethamine; Neoplasms; Neoplasms, Experimental; | 1958 |
Limiting factors in the prophylaxis of the spread of cancer at operation by chemotherapeutic methods.
Topics: Animals; Humans; Mechlorethamine; Neoplasms; Neoplasms, Experimental; Nitrogen Mustard Compounds | 1957 |
[Effect of fractionated doses of BCM [1,6-bix (beta-chloroethylamino)-1,6-desoxy-D-mannitol dihydrochloride] on guérin carcinoma of the rat].
Topics: Animals; Carcinoma; Dose Fractionation, Radiation; Mannitol; Mechlorethamine; Neoplasms, Experimenta | 1957 |
[Studies with the P32 indicator method on the inhibiting effect of nitrogen mustard N-oxide on Walker carcinoma and normal tissue of rats].
Topics: Animals; Carcinoma; Mechlorethamine; Neoplasms, Experimental; Nitrogen Mustard Compounds; Rats | 1958 |
[Effect of a cyclic nitrogen mustard-phosphamidester on experimentally induced tumors in rats; chemotherapeutic effect and pharmacological properties of B 518 ASTA].
Topics: Animals; Cyclophosphamide; Mechlorethamine; Neoplasms, Experimental; Nitrogen Mustard Compounds; Rat | 1958 |
[Complete cure of large Yoshida sarcomas with N-oxyd-mustard].
Topics: Animals; Mechlorethamine; Mustard Plant; Neoplasms, Experimental; Nitrogen Mustard Compounds; Sarcom | 1958 |
[Comparative studies of the effect of recent nitrogen derivatives on cancer in animals].
Topics: Animals; Mechlorethamine; Neoplasms; Neoplasms, Experimental; Nitrogen; Nitrogen Mustard Compounds | 1958 |
[Mechanism of action of B 518 (endoxan-Asia) jensen sarcoma and inhibition of chemotherapy of tumors by the vitamin nicotine acid amide].
Topics: Amides; Animals; Asia; Cyclophosphamide; Mechlorethamine; Neoplasms; Neoplasms, Experimental; Niacin | 1958 |
[Effect of barbamil on the therapeutic effect & toxicity of dopane].
Topics: Amobarbital; Animals; Mechlorethamine; Neoplasms, Experimental; Nitrogen Mustard Compounds; Uracil | 1958 |
[Effect of nitrogen mustard oxide on inoculation tumor].
Topics: Animals; Mechlorethamine; Neoplasms; Neoplasms, Experimental; Nitrogen Mustard Compounds; Oxides; Va | 1958 |
[Experimental principles of anti-tumor chemotherapy].
Topics: Animals; Mechlorethamine; Neoplasms; Neoplasms, Experimental; Nitrogen Mustard Compounds | 1958 |
[Combination of surgery and chemotherapy in cancer; model experiment on a resistant tumor in the rat].
Topics: Animals; Antineoplastic Agents; Mechlorethamine; Neoplasms, Experimental; Nitrogen Mustard Compounds | 1958 |
Prophylactic treatment of the Murphy Sturm rat lymphosarcoma with nitrogen mustard.
Topics: Lymphoma, Non-Hodgkin; Mechlorethamine; Neoplasms, Experimental; Nitrogen Mustard Compounds | 1958 |
Effect of 1, 6-di-(2-bromoethylamino)-1, 6-dideoxy-D-mannitol dihydrobromide on tumours of laboratory animals.
Topics: Animals; Animals, Laboratory; Mannitol; Mechlorethamine; Neoplasms; Neoplasms, Experimental; Nitroge | 1959 |
The action of 3,5,3 L-triiodothyronine and nitrogen mustard on the take of the Walker 256 rat tumor.
Topics: Animals; Mechlorethamine; Neoplasms; Neoplasms, Experimental; Nitrogen Mustard Compounds; Rats; Trii | 1958 |
[Combined effect of radioactive methionine and of sarcolysin on animal tumors].
Topics: Animals; Mechlorethamine; Melphalan; Methionine; Neoplasms; Neoplasms, Experimental; Nitrogen Mustar | 1959 |
[Effects of radiotherapy and chemotherapy on metastases of Guerin rat carcinoma].
Topics: Animals; Mannitol; Mechlorethamine; Neoplasms, Experimental; Neoplasms, Second Primary; Nitrogen Mus | 1959 |
[Method of control of gastrointestinal side effects during chlorethylamine therapy].
Topics: Animals; Gastrointestinal Tract; Humans; Mechlorethamine; Neoplasms, Experimental; Nitrogen Mustard | 1959 |
The effect of nitrogen mustard on circulating cancer cells and pulmonary metastases from an experimental cecal carcinoma.
Topics: Animals; Cecal Neoplasms; Cecum; Humans; Lung Neoplasms; Mechlorethamine; Neoplasms; Neoplasms, Expe | 1961 |
[Effect of the injection of methylbis(beta-chloroethyl) amine (caryolisine) on Ehrlich's experimental ascitic cancer].
Topics: Amines; Animals; Injections; Mechlorethamine; Neoplasms; Neoplasms, Experimental; Nitrogen Mustard C | 1961 |
[Daily periodic variations in the potency of the cancerostatic effect of nitrogen mustard oxide in Ehrlich ascites carcinoma in mice].
Topics: Animals; Ascites; Carcinoma; Mechlorethamine; Mice; Neoplasms, Experimental; Nitrogen Mustard Compou | 1961 |
Effects of colchicine and nitrogen mustard on Ehrlich's ascitic tumor in mice.
Topics: Animals; Carcinoma, Ehrlich Tumor; Colchicine; Mechlorethamine; Mice; Neoplasms, Experimental; Nitro | 1960 |
Antitumor activity of derivatives of nitrogen mustard containing a 2-chloroethyl group.
Topics: Animals; Mechlorethamine; Neoplasms, Experimental; Nitrogen Mustard Compounds | 1961 |
Mitomen chemotherapy given in relation to operation for Yoshida ascitic sarcoma in rats.
Topics: Animals; Mechlorethamine; Neoplasms, Experimental; Nitrogen Mustard Compounds; Rats; Sarcoma, Experi | 1959 |
[The effect of sarcolysin and dopan on the biosynthesis of pyrimidines of nucleic acid in transplanted tumors and tissues of the recipient organism].
Topics: Mechlorethamine; Melphalan; Neoplasms; Neoplasms, Experimental; Nitrogen Mustard Compounds; Nucleic | 1960 |
[On the resistance of tumor cells to chemotherapeutic agents].
Topics: Animals; Antineoplastic Agents; Biochemical Phenomena; Colchicine; Mechlorethamine; Neoplasms, Exper | 1960 |
[Can "specific" tumor therapy be improved by warmth?].
Topics: Animals; Body Temperature; Mechlorethamine; Neoplasms, Experimental; Nitrogen Mustard Compounds | 1960 |
Tumour-inhibiting action of 1,6-di-(2-bromoethyl-amino)-1,6-dideoxy-D-mannitol dihydrobromide [(DBM (R13)].
Topics: Animals; Humans; Mannitol; Mechlorethamine; Neoplasms; Neoplasms, Experimental; Nitrogen Mustard Com | 1959 |
Production of pulmonary metastases of the carcinosarcoma Walker 256. The effect of nitrogen mustard and Nitromin on growth potential.
Topics: Animals; Carcinosarcoma; Lung Neoplasms; Mechlorethamine; Neoplasms, Experimental; Nitrogen Mustard | 1962 |
Experimental abdominal perfusion with C-14-labeled nitrogen mustard.
Topics: Abdomen; Abdominal Cavity; Animals; Carbon; Carbon Radioisotopes; Mechlorethamine; Neoplasms, Experi | 1962 |
The comparison of intravenous and intra-arterial nitrogen mustard after the arterial injection of tumor cells.
Topics: Administration, Intravenous; Injections, Intra-Arterial; Injections, Intravenous; Mechlorethamine; N | 1963 |
Cancer research in Chile.
Topics: Antineoplastic Agents; Chile; Hexestrol; Lung Neoplasms; Mechlorethamine; Methylcholanthrene; Neopla | 1962 |
Influence of nitrogen mustard on tumor implantation.
Topics: Animals; Carcinoma; Carcinoma, Brown-Pearce; Mechlorethamine; Neoplasms; Neoplasms, Experimental | 1963 |
THE TRANSPORT OF14 C-LABELED NITROGEN MUSTARD N-OXIDE THROUGH CELLULAR MEMBRANE TREATED WITH TWEEN 80 IN VITRO.
Topics: Animals; Carbon Isotopes; Carcinoma, Hepatocellular; Cytoplasm; In Vitro Techniques; Liver Neoplasms | 1963 |
TUMOUR SULPHYDRYL LEVELS AND SENSITIVITY TO THE NITROGEN MUSTARD MEROPHAN.
Topics: Animals; Lymphoma; Mammary Neoplasms, Animal; Mammary Neoplasms, Experimental; Mechlorethamine; Mela | 1963 |
PROSTATE CANCER IN THE RAT.
Topics: Androgens; Estradiol Congeners; Estrogens; Estrone; Humans; Male; Mechlorethamine; Neoplasms; Neopla | 1963 |
EFFECTS OF CHEMICAL TREATMENT IN VITRO OF NELSON MOUSE ASCITES TUMOR CELLS ON THEIR TRANSPLANTABILITY AND ON SOME INDICES OF GLUCOSE METABOLISM.
Topics: Animals; Antineoplastic Agents; Ascites; Aziridines; Carbohydrate Metabolism; Carbon Isotopes; Carbo | 1963 |
[TUMOUR CHEMOTHERAPY. XII. SYNTHESIS OF NITROGEN MUSTARD RELATED TO ANTIARTHRITICS].
Topics: Chemistry, Pharmaceutical; Mechlorethamine; Neoplasms; Neoplasms, Experimental; Nitrogen Mustard Com | 1962 |
[TEST OF THE ACTION OF SOME NITROGEN MUSTARD DERIVATIVES ON STICKER'S LYMPHOSARCOMA].
Topics: Animals; Cyclophosphamide; Dogs; Lymphoma; Lymphoma, Non-Hodgkin; Mechlorethamine; Neoplasms; Neopla | 1963 |
ONCOLYSIS BY CLOSTRIDIA. III. EFFECTS OF CLOSTRIDIA AND CHEMOTHERAPEUTIC AGENTS ON RODENT TUMORS.
Topics: Adenocarcinoma; Animals; Antimetabolites; Antineoplastic Agents; Aziridines; Bacteriological Techniq | 1964 |
[THE REDUCTION OF RADIOPHOSPHORUS 32 INCORPORATION INTO CANCER CELLS BY NONTOXIC DOSES OF CYTOSTATIC SUBSTANCES].
Topics: Animals; Carcinoma; Carcinoma, Ehrlich Tumor; Cyclophosphamide; Cytostatic Agents; Mannomustine; Mec | 1963 |
THE ADVERSE EFFECTS OF CANCER CHEMOTHERAPY.
Topics: Animals; Antineoplastic Agents; Azaguanine; Carcinoma, Ehrlich Tumor; Cortisone; Cyclophosphamide; D | 1964 |
EFFECT OF LOCAL CHEMOTHERAPY OR A SMALL DOSE OF RADIOTHERAPY ON CANCER RECURRENCE.
Topics: Animals; Anti-Infective Agents, Local; Breast Neoplasms; Carcinoma; Halogens; Humans; Hydrocarbons, | 1964 |
COMPARATIVE RESPONSE OF A SPECTRUM OF TRANSPLANTABLE RAT NEOPLASMS TO NITROGEN MUSTARD, TRIETHYLENEMELAMINE, AND A GROUP OF BENZALDEHYDE MUSTARD DERIVATIVES.
Topics: Animals; Benzaldehydes; Carcinoma, Bronchogenic; Carcinoma, Hepatocellular; Female; Humans; Injectio | 1964 |
THE EFFECT OF NITROGEN MUSTARD ON THE LIFE CYCLE OF EHRLICH ASCITES TUMOR CELLS IN VIVO.
Topics: Animals; Carcinoma; Carcinoma, Ehrlich Tumor; Cystine; DNA; DNA, Neoplasm; Leucine; Mechlorethamine; | 1964 |
HETEROGENEITY OF CANCER CELL POPULATION WITH RESPECT TO NATURAL DRUG RESISTANCE OF CONSTITUENT CELLS.
Topics: Carcinoma, Hepatocellular; Drug Resistance; Liver Neoplasms; Mechlorethamine; Neoplasms; Neoplasms, | 1964 |
SUSCEPTIBILITY OF INJURED TISSUES TO HEMATOGENOUS METASTASES: AN EXPERIMENTAL STUDY.
Topics: Abdominal Wall; Chemotherapy, Cancer, Regional Perfusion; Dextrans; Disease Susceptibility; Ischemia | 1964 |
SYNTHESIS OF POSSIBLE CANCER CHEMOTHERAPEUTIC COMPOUNDS BASED ON ENZYME APPROACH. V. TETRAZOLIUM NITROGEN MUSTARDS.
Topics: Animals; Carcinoma; Carcinoma 256, Walker; Chemistry, Pharmaceutical; Leukemia; Leukemia, Experiment | 1963 |
EFFECT OF HYPERBARIC OXYGEN AND CANCER CHEMOTHERAPY ON GROWTH OF ANIMAL TUMORS.
Topics: Animals; Cricetinae; Humans; Hyperbaric Oxygenation; Injections, Intraperitoneal; Lung Neoplasms; Me | 1964 |
EXPERIMENTAL CHEMOTHERAPY STUDIES. 3. PROPERTIES OF DNA FROM ASCITES CELLS TREATED IN VIVO WITH NITROGEN MUSTARD.
Topics: Animals; Ascites; Carbon Isotopes; Carcinoma; Carcinoma, Ehrlich Tumor; DNA; DNA, Viral; Mechloretha | 1964 |
A NITROGEN MUSTARD DERIVATIVE OF 6-MERCAPTOPURINE.
Topics: Animals; Chemistry, Pharmaceutical; Cricetinae; Mechlorethamine; Mercaptopurine; Mice; Neoplasms; Ne | 1964 |
PLASMA CELL NEOPLASM ARISING IN A CAF MOUSE. CHARACTERISTICS AND RESPONSE TO CERTAIN CHEMOTHERAPEUTIC AGENTS.
Topics: Adenocarcinoma; Alkylating Agents; Animals; Antineoplastic Agents; Bence Jones Protein; Cecum; Cyclo | 1964 |
MUTUAL ADHESIVENESS OF TUMOR CELLS IN "HEPATOMA ISLAND" OF THE RAT ASCITES HEPATOMA. 3. THE INFLUENCE OF NITROGEN MUSTARD N-OXIDE.
Topics: Adhesiveness; Ascites; Carcinoma, Hepatocellular; Islands; Liver Neoplasms; Mechlorethamine; Neoplas | 1964 |
[STUDIES ON THE EFFECT OF NEW NITROGEN MUSTARD ANALOGES ON NK/LY TRANSPLANTABLE TUMORS].
Topics: Animals; Mechlorethamine; Mice; Neoplasm Transplantation; Neoplasms; Neoplasms, Experimental; Nitrog | 1964 |
ACRIDINE AND QUINOLINE ANALOGS OF NITROGEN MUSTARD WITH AMIDE SIDE CHAINS.
Topics: Acridines; Amides; Animals; Chemistry, Pharmaceutical; Mechlorethamine; Mice; Neoplasms; Neoplasms, | 1964 |
POTENTIAL ANTICANCER AGENTS. IV. HETEROCYCLIC PHOSPHORAMIDE NITROGEN MUSTARDS.
Topics: Antineoplastic Agents; Carcinoma 256, Walker; Chemistry, Pharmaceutical; Mechlorethamine; Neoplasms; | 1964 |
CYANO ANALOGS OF PHENOLIC NITROGEN MUSTARDS.
Topics: Animals; Carcinoma; Carcinoma 256, Walker; Chemistry, Pharmaceutical; Leukemia L1210; Mechlorethamin | 1964 |
"NATURAL" DRUG RESISTANCE OF THE ASCITES HEPATOMA IN THE RAT.
Topics: Animals; Ascites; Carcinoma, Hepatocellular; Drug Resistance; Drug Tolerance; Freezing; Genetics; Li | 1964 |
CANCER METASTASIS AND ASCITES TUMORS.
Topics: Animals; Anti-Bacterial Agents; Antineoplastic Agents; Ascites; Carcinoma, Ehrlich Tumor; Carcinoma, | 1964 |
[RESEARCH ON THE ANTIBLASTIC ACTION OF A NITROGEN MUSTARD OF THE URETHANE TYPE BOUND TO HYDROCORTISONE].
Topics: Animals; Carcinoma; Carcinoma 256, Walker; Carcinoma, Ehrlich Tumor; Hydrocortisone; Mammary Neoplas | 1964 |
[DEVELOPMENT OF FREE-CELL SUBLINES OF THE ASCITES HEPATOMA AH-130 AND THEIR BIOLOGICAL PROPERTIES].
Topics: Ascites; Carcinoma, Hepatocellular; Chromosomes; Electrons; Liver Neoplasms; Mechlorethamine; Micros | 1964 |
FURTHER OBSERVATIONS ON LATE SOMATIC EFFECTS OF RADIOMIMETIC CHEMICALS AND X-RAYS IN MICE.
Topics: Aging; Busulfan; Cataract; Female; Humans; Leukemia; Leukemia, Myeloid; Longevity; Lung Neoplasms; L | 1965 |
URACIL MUSTARD: A POTENT INDUCER OF LUNG TUMORS IN MICE.
Topics: DNA; Lung Neoplasms; Mechlorethamine; Mice; Neoplasms; Neoplasms, Experimental; Nitrogen Mustard Com | 1965 |
HEPATIC AND PULMONARY METASTASES FROM A RESECTABLE EXPERIMENTAL CECAL CARCINOMA: THE EFFECT OF HEPATIC PERFUSION WITH NITROGEN MUSTARD COMBINED WITH SYSTEMIC HEPARIN AND FIBRINOLYSIN.
Topics: Blood; Cecal Neoplasms; Fibrinolysin; Heparin; Liver Neoplasms; Lung Neoplasms; Mechlorethamine; Neo | 1964 |
STUDIES ON THE METABOLISM OF RAT-ASCITES-HEPATOMA WITH NITROGEN MUSTARD SENSITIVE AND RESISTANT STRAINS. 8. EFFECT OF CHROMOMYCIN A3 ON THE NUCLEAR RNA METABOLISM.
Topics: Anti-Bacterial Agents; Ascites; Carcinoma, Hepatocellular; Cell Nucleus; Chromomycin A3; Dactinomyci | 1965 |
SYNTHESIS AND ANTITUMOR ACTIVITY OF 9-SUBSTITUTED NITROGEN MUSTARD DERIVATIVES OF 6-ALKYLTHIOPURINES.
Topics: Animals; Chemistry, Pharmaceutical; Mechlorethamine; Mice; Neoplasms; Neoplasms, Experimental; Nitro | 1965 |
The in vitro initiation of pulmonary adenomas in mouse lung tissue with nitrogen mustard. I. The influences of concentration of agent, duration of exposure, and mitotic state of the tissue at the time of exposure.
Topics: Adenoma; Animals; In Vitro Techniques; Lung Neoplasms; Mechlorethamine; Mice; Neoplasms, Experimenta | 1955 |
Increased antitumor action of nitrogen mutard caused by induced hypothyroidism.
Topics: Animals; Hypothyroidism; Mechlorethamine; Neoplasms, Experimental; Nitrogen; Nitrogen Mustard Compou | 1960 |
An experimental study in local (regional) chemotherapy of the intrahepatically implanted Brown--Pearce tumour in the rabbit.
Topics: Animals; Liver Neoplasms, Experimental; Mechlorethamine; Neoplasms; Neoplasms, Experimental; Nitroge | 1959 |
Anti-cancer action of derivatives of 2-chloroethylamine.
Topics: Animals; Ethylamines; Humans; Mechlorethamine; Neoplasms; Neoplasms, Experimental; Nitrogen Mustard | 1959 |
Experimental studies on the effects of nitromin (nitrogen mustard N-oxide) upon tumor growth, with special respect to inhibition of metastasis formation.
Topics: Animals; Mechlorethamine; Neoplasms; Neoplasms, Experimental; Neoplasms, Second Primary; Nitrogen Mu | 1959 |
[Electron microscope studies of cancer cells. Influence of nitromin on ascites hepatoma].
Topics: Animals; Ascites; Carcinoma, Hepatocellular; Electrons; Liver Neoplasms; Mechlorethamine; Microscopy | 1962 |
[Studies on the effect of sarcolysine on transplantable tumors of mice].
Topics: Animals; Mechlorethamine; Melphalan; Mice; Neoplasms, Experimental; Nitrogen Mustard Compounds | 1961 |
Studies on the metabolism of rat-ascites-tumor with nitrogen mustard sensitive and resistant strains. VII. Effect of ubiquinone a vitamin K3 on succinate- and alpha-glyceropnosphate-neotetrazolium reductase.
Topics: Animals; Ascites; Carcinoma, Hepatocellular; Coenzymes; Electron Transport Complex II; Liver Neoplas | 1962 |
Experimental chemotherapy studies. I. Chemical and metabolic investigations of chloroquine mustard.
Topics: Animals; Chloroquine; Mechlorethamine; Mustard Plant; Neoplasms, Experimental; Nitrogen Mustard Comp | 1961 |
Studies in a tumor spectrum. I. Comparison of the action of methylbis (2-chloroethyl)amine and 3-bis(2-chloroethyl)aminomethyl-4-methoxymethyl -5-hydroxy-6-methylpyridine on the growth of a variety of mouse and rat tumors.
Topics: Amines; Animals; Ethylamines; Mechlorethamine; Mice; Neoplasms; Neoplasms, Experimental; Nitrogen Mu | 1952 |
The induction of tumours with nitrogen mustards.
Topics: Animals; Ethylamines; Lipids; Mechlorethamine; Neoplasms; Neoplasms, Experimental | 1949 |
A model system for examining the action of anti-cancer agents at the cellular level in vivo.
Topics: Animals; Antineoplastic Agents; Azaserine; Cyclophosphamide; Dactinomycin; Fluorouracil; Hematopoies | 1967 |
Dichloroethyl carbamoyl ester of delta-9-tetrahydrocannabinol. Chemical synthesis and biological testing and evaluation as a potentially site-specific anti-tumor agent.
Topics: Animals; Antineoplastic Agents; Cells, Cultured; Dronabinol; Drug Evaluation, Preclinical; Drug Syne | 1984 |
The role of WR-2721 in radiotherapy and/or chemotherapy.
Topics: Alkylating Agents; Amifostine; Animals; Breast Neoplasms; Cyclophosphamide; Humans; In Vitro Techniq | 1980 |
Prostaglandin E augments the effect of chemotherapy on B-16 melanoma in vivo.
Topics: Animals; Antineoplastic Agents; Dopamine; Doxorubicin; Drug Therapy, Combination; Female; Fluorourac | 1982 |
Amphotericin B (Fungizone R) enhancement of nitrogen mustard uptake by human tumor cells.
Topics: Amphotericin B; Biological Transport; Carcinoma, Squamous Cell; Carrier Proteins; Cells, Cultured; C | 1980 |
Tumorigenic effect of topical mechlorethamine, BCNU and CCNU in mice.
Topics: Animals; Carcinogens; Carcinoma, Squamous Cell; Carmustine; Lomustine; Mechlorethamine; Mice; Neopla | 1980 |
DNA damage in rat 9L cells treated with nitrogen mustard and 1,3-bis(2-chloroethyl)-1-nitrosourea assayed by viscoelastometry and S1 nuclease.
Topics: Animals; Brain Neoplasms; Carmustine; Cell Line; Cross-Linking Reagents; Deoxyribonucleases; DNA, Ne | 1980 |
[Antitumor activity of thevetoside alone and in combination with chlormethine in vivo].
Topics: Animals; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Cardiac | 1994 |
Double high-dose chemotherapy with stem cell rescue (HD-SCR) in patients with breast cancer - effect of sequence.
Topics: Alkylating Agents; Animals; Antineoplastic Agents; Breast Neoplasms; Carmustine; Cell Survival; Cisp | 2000 |
Comparative study of early effects of epipodophyllotoxin derivatives and other cytostatic agents on mastocytoma cultures.
Topics: Antineoplastic Agents; Bleomycin; Cell Division; Cell Line; Colchicine; Cytarabine; DNA, Neoplasm; E | 1977 |
Action of radiation or alkylating agents on LSA lymphoma during growth.
Topics: Alkylating Agents; Animals; Carmustine; Cell Survival; Cobalt Radioisotopes; Cyclophosphamide; Dose- | 1979 |
Experimental study on drug sensitivity of the rat ascites hepatoma cells in embryonated eggs.
Topics: Animals; Carcinoma, Hepatocellular; Chick Embryo; Drug Evaluation, Preclinical; Fluorouracil; Liver | 1975 |
Role of DNA repair in natural resistance of rat ascites hepatomas to nitrogen mustard.
Topics: Animals; Biological Transport; Carcinoma, Hepatocellular; Cell Line; Cell Survival; Choline; DNA Rep | 1977 |
Differential protection of normal and malignant tissues against the cytotoxic effects of mechlorethamine.
Topics: Amifostine; Animals; Bone Marrow; Drug Tolerance; Female; Lethal Dose 50; Lung Neoplasms; Mechloreth | 1979 |
Influence of chemotherapeutic agents on chorionic gonadotropin-alpha subunit secretion in a human lung cancer cell line (ChaGo): discordance of cytotoxic and secretory effects.
Topics: Antineoplastic Agents; Cell Division; Cell Line; Chorionic Gonadotropin; Dactinomycin; Hormones, Ect | 1978 |
[Comparative characteristics of the toxicity and antitumor activity of a number of haloid derivatives of embikhin and Nor HN2].
Topics: Animals; Drug Evaluation, Preclinical; Female; Lethal Dose 50; Male; Mechlorethamine; Mice; Neoplasm | 1979 |
In vitro analysis of the response of multicellular tumor spheroids exposed to chemotherapeutic agents in vitro or in vivo.
Topics: Animals; Antineoplastic Agents; Cell Division; Cell Line; Cyclophosphamide; Dose-Response Relationsh | 1978 |
Effect of hyperbaric oxygen on the cytotoxicity of adriamycin and nitrogen mustard in cultured Burkitt's lymphoma cells.
Topics: Burkitt Lymphoma; Cell Survival; Cells, Cultured; Doxorubicin; Hyperbaric Oxygenation; Mechlorethami | 1979 |
Study of in vivo tumor state and response to therapy by analysis of DNA distribution.
Topics: Animals; Carmustine; Cell Survival; Cobalt Radioisotopes; DNA, Neoplasm; Female; Hydroxyurea; Kineti | 1976 |
Changes in sensitivity to cytotoxic agents occurring during the life history of monolayer cultures of a mouse tumour cell line.
Topics: Alkylating Agents; Animals; Antibiotics, Antineoplastic; Carmustine; Cell Division; Cell Line; Cell | 1975 |
The response to cytotoxic drugs of EMT6 cells treated either as intact or disaggregated spheroids.
Topics: Animals; Antineoplastic Agents; Cell Aggregation; Cell Line; Cell Survival; Dose-Response Relationsh | 1985 |
Experimental use of cetrimide in the prevention of wound implantation with cancer cells.
Topics: Animals; Anti-Infective Agents, Local; Antineoplastic Agents; Mechlorethamine; Mice; Neoplasm Metast | 1966 |
Amyloidosis in mice bearing a transplantable plasma cell tumour.
Topics: Amyloidosis; Animals; Cortisone; Diet; Electrophoresis; gamma-Globulins; Mechlorethamine; Melphalan; | 1967 |
[On the dosage range and scattering of effective dosage in the human body in cancer chemotherapy with N-oxide-mustard].
Topics: Animals; Carcinoma, Ehrlich Tumor; Mechlorethamine; Neoplasms, Experimental; Rabbits | 1966 |
[Histochemical and biochemical studies on the effects of anticancer agents on glycogen metabolism in AH13 ascites hepatoma].
Topics: Animals; Antineoplastic Agents; Ascites; Carcinoma, Hepatocellular; Cyclophosphamide; Female; Glucos | 1969 |
Increase of glycogen and oligosaccharide contents in ascites tumor cells under the influence of alkylating agents.
Topics: Alkylating Agents; Animals; Antineoplastic Agents; Ascites; Carcinoma, Hepatocellular; Cobalt Isotop | 1969 |
Tissue NAD levels and the response to irradiation of cytotoxic drugs.
Topics: Animals; beta-Aminoethyl Isothiourea; Cysteamine; Female; Lymphoma; Male; Mechlorethamine; Mice; NAD | 1970 |
Study on the sensitivity test of carcinostatic agents by acid phosphatase activity.
Topics: Acid Phosphatase; Adult; Aged; Animals; Antineoplastic Agents; Chromomycins; Cyclophosphamide; Femal | 1972 |
Relative effects of varying concentrations of cytotoxic drugs in vitro on tumour and reticulo-endothelial tissue.
Topics: Animals; Antineoplastic Agents; DNA; DNA, Neoplasm; Fluorouracil; Glucose; In Vitro Techniques; Mamm | 1968 |
[Experimental study of the antineoplastic effect of the antibiotic polymycin].
Topics: Animals; Anti-Bacterial Agents; Antibiotics, Antineoplastic; Antifungal Agents; Antiviral Agents; As | 1970 |
Surgical chemotherapy for treatment of experimental tumors (animals) and far advanced tumors (humans).
Topics: Animals; Chemotherapy, Cancer, Regional Perfusion; Head and Neck Neoplasms; Humans; Injections, Intr | 1972 |
Differential effects of nitrogen mustard, melphalan and vinblastine on the metabolism of mouse tumour and spleen slices.
Topics: Adenocarcinoma; Animals; DNA; Female; Mechlorethamine; Melphalan; Mice; Neoplasms, Experimental; Pro | 1969 |
Studies on the role of host resistance in the therapy of mouse ascites hepatoma MH 134.
Topics: Animals; Hemolysin Proteins; Mechlorethamine; Mice; Mitomycins; Neoplasms, Experimental; Spleen | 1967 |
Growth inhibitory and haematological effects of alkylating agents and attempts at their modification to give greater selectivity of anti-tumour action.
Topics: Alkylating Agents; Animals; Body Weight; Carcinoma 256, Walker; Chemical Phenomena; Chemistry; Chlor | 1968 |
Potential anticancer agents. V. New aromatic nitrogen mustards related to 3-[N,N-bis(2-chloroethyl)amino]-4-methylbenzoic acid.
Topics: Amides; Animals; Antineoplastic Agents; Benzoates; Carcinoma 256, Walker; Chemical Phenomena; Chemis | 1969 |
Relation of thymidine index to pulmonary tumor response in mice receiving urethan and other carcinogens.
Topics: Animals; Autoradiography; Carbamates; Carcinogens; Cytarabine; Dactinomycin; DNA; Fluorouracil; Inje | 1969 |
Response of a "resistant" plasmacytoma to alkylating agents and x-ray in combination with the "excision" repair inhibitors caffeine and chloroquine.
Topics: Animals; Caffeine; Chloroquine; Cricetinae; Cyclophosphamide; Depression, Chemical; DNA, Neoplasm; M | 1969 |
Preoperative irradiation and chemotherapy in the prevention of surgical failures: experimental observations on an animal tumor model.
Topics: Animals; Antineoplastic Agents; Cyclophosphamide; Lymphoma, Non-Hodgkin; Mechlorethamine; Mice; Mode | 1969 |
[Importance of nitrogen mustard as a co-adjuvant therapy of an experimental lung tumor].
Topics: Animals; Lung Neoplasms; Mechlorethamine; Neoplasms, Experimental; Pneumonectomy; Rabbits | 1964 |
The effect of x-irradiation on the take and growth of the guerin-tumour. II. Histological experiments.
Topics: Animals; Mannomustine; Mechlorethamine; Melphalan; Neoplasm Transplantation; Neoplasms, Experimental | 1965 |
Cetrimide as an irrigant in wounds seeded with cancer.
Topics: Animals; Anti-Infective Agents, Local; Female; Hydrogen Peroxide; Mechlorethamine; Mice; Neoplasm Me | 1966 |
Autoradiographic whole body studies of 14C-nitrogen mustard in normal and tumour-bearing mice.
Topics: Animals; Autoradiography; Carbon Isotopes; Mechlorethamine; Mice; Neoplasms, Experimental | 1966 |
Experimental studies on lung tumor by implantation of tumor cells through the air passage.
Topics: Animals; Antibiotics, Antineoplastic; Antineoplastic Agents; In Vitro Techniques; Lung Neoplasms; Ma | 1966 |