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mechlorethamine and Emesis

mechlorethamine has been researched along with Emesis in 17 studies

nitrogen mustard : Compounds having two beta-haloalkyl groups bound to a nitrogen atom, as in (X-CH2-CH2)2NR.

Research Excerpts

ExcerptRelevanceReference
" Therefore, in this study we evaluated, in cancer patients, the temporal relationships between the increases in plasma CgA and urinary 5-hydroxyindoleacetic acid (5-HIAA) and the development of vomiting following dacarbazine, nitrogen mustard and cyclophosphamide treatments."7.69Plasma chromogranin A marks emesis and serotonin release associated with dacarbazine and nitrogen mustard but not with cyclophosphamide-based chemotherapies. ( Cubeddu, LX; Hoffmann, I; O'Connor, DT; Parmer, RJ, 1995)
"Sixty-four patients receiving cancer chemotherapy known to induce severe emesis entered a randomized double-blind study of the antiemetic efficacy of haloperidol (Haldol) and benzquinamide (Emetecon)."5.05Specific antiemetics for specific cancer chemotherapeutic agents: haloperidol versus benzquinamide. ( Gagen, M; Neidhart, JA; Wilson, HE; Young, D, 1981)
" Therefore, in this study we evaluated, in cancer patients, the temporal relationships between the increases in plasma CgA and urinary 5-hydroxyindoleacetic acid (5-HIAA) and the development of vomiting following dacarbazine, nitrogen mustard and cyclophosphamide treatments."3.69Plasma chromogranin A marks emesis and serotonin release associated with dacarbazine and nitrogen mustard but not with cyclophosphamide-based chemotherapies. ( Cubeddu, LX; Hoffmann, I; O'Connor, DT; Parmer, RJ, 1995)
"Seventy patients with advanced Hodgkin's disease, 54 with new disease, and 16 in first relapse after initial radiotherapy, have been treated with a seven-drug, 8-month program: MOPP (nitrogen mustard, vincristine, procarbazine, prednisone)/ABV (Adriamycin [Adria Laboratories of Canada, Mississauga, Ontario], bleomycin, vinblastine) hybrid."1.27MOPP/ABV hybrid program: combination chemotherapy based on early introduction of seven effective drugs for advanced Hodgkin's disease. ( Connors, JM; Klimo, P, 1985)

Research

Studies (17)

TimeframeStudies, this research(%)All Research%
pre-199015 (88.24)18.7374
1990's2 (11.76)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
HEIDELMANN, G1
BORISON, HL1
BRAND, ED1
ORKAND, RK1
MORINI, A1
BLAKE, JM1
HAYFORD, FC1
JUSTIN-BESANCON, L1
GRIVAUX, M2
CORNET, A1
TOURNEUR, R2
GUERRE, J1
LAMOTTE-BARRILLON, S1
DOMOKOS, J1
KELEMEN, E1
Straus, DJ1
Myers, J1
Passe, S1
Young, CW1
Nisce, LZ1
Lee, BJ1
Koziner, B1
Arlin, Z1
Kempin, S1
Gee, T1
Clarkson, BD1
Neidhart, JA1
Gagen, M1
Young, D1
Wilson, HE1
Cubeddu, LX1
O'Connor, DT1
Hoffmann, I1
Parmer, RJ1
Jurcic, JG1
Koll, B1
Brown, AE1
Crown, JP1
Yahalom, J1
Gulati, SC1
Klimo, P1
Connors, JM1
Lowenthal, RM1
Jestrimski, KW1
Griffiths, JD1
Papp, RH1
Hawkins, HB1
Share, NN1
Wang, SC1
Smirnova, IN1
Traldi, A1
Vaccari, GL1
Davoli, G1

Reviews

1 review available for mechlorethamine and Emesis

ArticleYear
Corticosteroid drugs: their role in oncological practice.
    The Medical journal of Australia, 1986, Jan-20, Volume: 144, Issue:2

    Topics: Adrenal Cortex Hormones; Animals; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Breast

1986

Trials

2 trials available for mechlorethamine and Emesis

ArticleYear
The eight-drug/radiation therapy program (MOPP/ABDV/RT) for advanced Hodgkin's disease: a follow-up report.
    Cancer, 1980, Jul-15, Volume: 46, Issue:2

    Topics: Adolescent; Adult; Antineoplastic Agents; Bleomycin; Dacarbazine; Doxorubicin; Drug Administration S

1980
Specific antiemetics for specific cancer chemotherapeutic agents: haloperidol versus benzquinamide.
    Cancer, 1981, Mar-15, Volume: 47, Issue:6

    Topics: Adult; Antineoplastic Agents; Cisplatin; Clinical Trials as Topic; Double-Blind Method; Doxorubicin;

1981

Other Studies

14 other studies available for mechlorethamine and Emesis

ArticleYear
[Clinical experience with an antihistamine-xanthine compound, used as antiemetic in roentgen intoxication and in nitrogen mustard therapy].
    Deutsche medizinische Wochenschrift (1946), 1952, Nov-14, Volume: 77, Issue:46

    Topics: Antiemetics; Histamine H1 Antagonists; Humans; Mechlorethamine; Nitrogen Mustard Compounds; Radiatio

1952
Emetic action of nitrogen mustard (mechlorethamine hydrochloride) in dogs and cats.
    The American journal of physiology, 1958, Volume: 192, Issue:2

    Topics: Animals; Cats; Dogs; Emetics; Mechlorethamine; Nitrogen Mustard Compounds; Vomiting

1958
[Use of chlorpromazine in the treatment of vomiting caused by methyl-bis-(beta-chlorethyl)amine].
    La Riforma medica, 1958, May-24, Volume: 72, Issue:21

    Topics: Amines; Chlorpromazine; Humans; Mechlorethamine; Nitrogen Mustard Compounds; Vomiting

1958
Use of triflupromazine hydrochloride for control of emetic reactions to nitrogen mustard therapy.
    New York state journal of medicine, 1960, Jul-01, Volume: 60

    Topics: Emetics; Humans; Mechlorethamine; Nitrogen Mustard Compounds; Phenothiazines; Triflupromazine; Vomit

1960
[RESEARCH ON CERTAIN DIGESTIVE DYSKINESIAS AND FUNCTIONAL DISORDERS].
    Bulletins et memoires de la Societe medicale des hopitaux de Paris, 1964, May-15, Volume: 115

    Topics: Antiemetics; Apomorphine; Cobalt Isotopes; Cyclophosphamide; Digitalis Glycosides; Dyskinesias; Dysp

1964
[DIGESTIVE INTOLERANCE TO DIGITALIN, CYTOSTATIC DRUGS AND VARIOUS THERAPEUTIC DRUGS. THEIR TREATMENT WITH METHOCLOPRAMIDE].
    La semaine des hopitaux : organe fonde par l'Association d'enseignement medical des hopitaux de Paris, 1964, Oct-14, Volume: 40

    Topics: Antiemetics; Antitubercular Agents; Cobalt Isotopes; Cyclophosphamide; Cytostatic Agents; Digitalis

1964
[Clinical and animal experiments on the prevention of vomiting and of bone marrow damage due to nitrogen mustard by the use of pyridoxine and choline, respectively].
    Orvosi hetilap, 1950, Jun-04, Volume: 91, Issue:23

    Topics: Animal Experimentation; Animals; Biomedical Research; Bone Marrow; Choline; Humans; Mechlorethamine;

1950
Plasma chromogranin A marks emesis and serotonin release associated with dacarbazine and nitrogen mustard but not with cyclophosphamide-based chemotherapies.
    British journal of cancer, 1995, Volume: 72, Issue:4

    Topics: Adult; Antineoplastic Agents; Chromogranin A; Chromogranins; Cyclophosphamide; Dacarbazine; Female;

1995
Excretion of Ascaris lumbricoides during total body irradiation.
    Bone marrow transplantation, 1994, Volume: 13, Issue:4

    Topics: Adult; Animals; Antineoplastic Combined Chemotherapy Protocols; Ascariasis; Ascaris lumbricoides; Bo

1994
MOPP/ABV hybrid program: combination chemotherapy based on early introduction of seven effective drugs for advanced Hodgkin's disease.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1985, Volume: 3, Issue:9

    Topics: Actuarial Analysis; Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomyc

1985
Mallory-Weiss tear and cytotoxic-induced emesis.
    The Medical journal of Australia, 1986, Jan-20, Volume: 144, Issue:2

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Hodgkin Disease; Humans; Male; Mallory-Weiss

1986
Emesis induced by the intracerebroventricular administration of hydergine and mechlorethamine hydrochloride.
    The Journal of pharmacology and experimental therapeutics, 1966, Volume: 154, Issue:2

    Topics: Animals; Cerebral Ventricles; Chlorpromazine; Dogs; Emetics; Ergoloid Mesylates; Mechlorethamine; Pe

1966
[Results of treatment of tonsillar tumors by olivomycin].
    Antibiotiki, 1969, Volume: 14, Issue:3

    Topics: Adolescent; Adult; Antibiotics, Antineoplastic; Carcinoma, Squamous Cell; Chlorpromazine; Cyclophosp

1969
[Use of the imide of N-phthalylglutamic acid (thalidomide) in the symptomatic therapy of vomiting of many patients with malignant neoplasms or caused by the administration of mechlorethamine HCl].
    Il Cancro, 1965, Volume: 18, Issue:4

    Topics: Adolescent; Adult; Aged; Child; Female; Humans; Male; Mechlorethamine; Middle Aged; Neoplasms; Thali

1965